Medical News

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• Topical simvastatin may be answer to nonhealing diabetic wounds
• Air quality in cities linked to inflammatory risk in diabetes
• Infrared therapy could help prevent anal cancer in HIV-positive population
• Tdap well tolerated in over-65s
• Phone, letter prompts improve statin uptake
• Orthopedic surgery relieves breast cancer metastases
• Infrared therapy could help prevent anal cancer in HIV-positive population
• Asthma and nasal congestion common insomnia triggers
• Altered cognition, attitudes mostly state related in bipolar disorder

Topical simvastatin may be answer to nonhealing diabetic wounds Posted: 29 Nov 2012 04:00 PM PST Topical simvastatin significantly accelerates wound healing in mice and may be a good treatment option for diabetic patients with nonhealing wounds, say researchers.

Air quality in cities linked to inflammatory risk in diabetes Posted: 29 Nov 2012 04:00 PM PST Exposure to traffic-related air pollutants is associated with a rapid increase in systemic inflammation in patients with diabetes, report Indian researchers.

Infrared therapy could help prevent anal cancer in HIV-positive population Posted: 29 Nov 2012 04:00 PM PST Infrared coagulopathy treatment of a potential precursor of anal cancer is effective and warrants further study as a way to reduce anal cancer incidence and mortality among HIV-infected people, report researchers.

Tdap well tolerated in over-65s Posted: 29 Nov 2012 04:00 PM PST Off-label use of tetanus–diptheria–acellular pertussis vaccine in senior patients results in no more adverse events than the tetanus and diphtheria vaccine, a US study shows.

Phone, letter prompts improve statin uptake Posted: 29 Nov 2012 04:00 PM PST Telephoning and writing to individuals who have not filled their new prescription for statin medication significantly improves rates of prescription uptake, show US study results.

Orthopedic surgery relieves breast cancer metastases Posted: 29 Nov 2012 04:00 PM PST Results of a review demonstrate the key role orthopedic surgery can play in the care of breast cancer patients with bone metastases.

Infrared therapy could help prevent anal cancer in HIV-positive population Posted: 29 Nov 2012 04:00 PM PST Infrared coagulopathy treatment of a potential precursor of anal cancer is effective and warrants further study as a way to reduce anal cancer incidence and mortality among HIV-infected people, report researchers.

Asthma and nasal congestion common insomnia triggers Posted: 29 Nov 2012 04:00 PM PST Insomnia is a common problem in patients with asthma, suggests research published in Allergy.

Altered cognition, attitudes mostly state related in bipolar disorder Posted: 22 Nov 2012 04:00 PM PST Altered cognitive processes and attitudes in patients with bipolar disorder are mostly associated with symptomatology, say researchers.

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iPhone Medical News

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FH Diagnosis | Medical App Review Posted: 29 Nov 2012 03:38 AM PST FH Diagnosis is a free iPhone app designed to assist in the diagnosis of Familial Hypercholesterolaemia (FH) using the Dutch Lipid, MEDPED, and Simon Broome criteria for FH. These complex diagnostic criteria are rarely used, except in lipid-specialty clinics, for the diagnosis of potential FH.  This easy to use app provides a tool that any healthcare professional can use to establish a diagnosis of FH and start appropriate treatment for this disorder that can lead to premature cardiovascular death. The user interface of FH Diagnosis is straight forward, nothing is complicated or difficult to use. FH Diagnosis is strongly recommended for primary care providers and specialist physicians who manage patients with lipid disorders.   The medical content advisor for FH Diagnosis is Gregory Thomas, MD, MPH, FACC, FASNC. Dr Thomas is known for co-leading the interdisciplinary team that found atherosclerosis in ancient Egyptian mummies.  (JAMA 2009;302(19):2091-2094.) This app was created by KKIT Creations LLC using support from Genzyme, a pharmaceutical company.  There appears to be no promotional bias in this app.

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Medical News

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• Evidence of neurobiologic differences between bipolar subtypes
• Poor empathy may feature in common psychiatric conditions
• Evidence of neurobiologic differences between bipolar subtypes
• Poor empathy may feature in common psychiatric conditions
• Poor empathy may feature in common psychiatric conditions
• Imaging window into future for brain injury patients
• High–fructose corn syrup use linked to diabetes
• Reoperation not reliable indicator for hernia recurrence
• Regorafenib phase III results strongly support use in GIST
• Regorafenib phase III results strongly support use in GIST

Evidence of neurobiologic differences between bipolar subtypes Posted: 29 Nov 2012 04:00 PM PST Taiwanese researchers have found differences in fronto-limbic metabolism and executive function between patients with bipolar disorder I and II.

Poor empathy may feature in common psychiatric conditions Posted: 29 Nov 2012 04:00 PM PST Individuals with schizophrenia, bipolar disorder, or depression may be less empathic than individuals without these conditions, according to German study results.

Evidence of neurobiologic differences between bipolar subtypes Posted: 29 Nov 2012 04:00 PM PST Taiwanese researchers have found differences in fronto-limbic metabolism and executive function between patients with bipolar disorder I and II.

Poor empathy may feature in common psychiatric conditions Posted: 29 Nov 2012 04:00 PM PST Individuals with schizophrenia, bipolar disorder, or depression may be less empathic than individuals without these conditions, according to German study results.

Poor empathy may feature in common psychiatric conditions Posted: 29 Nov 2012 04:00 PM PST Individuals with schizophrenia, bipolar disorder, or depression may be less empathic than individuals without these conditions, according to German study results.

Imaging window into future for brain injury patients Posted: 28 Nov 2012 04:00 PM PST A model based on quantitative diffusion tensor imaging findings predicts outcomes after severe traumatic brain injury better than current methods, shows a multicenter study.

High–fructose corn syrup use linked to diabetes Posted: 28 Nov 2012 04:00 PM PST Countries that have opted to use high-fructose corn syrup in their food and drink industry have a 20% higher mean prevalence of diabetes than countries that have minimal use of or do not use the sweetener.

Reoperation not reliable indicator for hernia recurrence Posted: 28 Nov 2012 04:00 PM PST Using reoperation rates as the indicator for recurrence after ventral hernia repair may underestimate the true recurrence rate, according to Danish study findings.

Regorafenib phase III results strongly support use in GIST Posted: 28 Nov 2012 04:00 PM PST Regorafenib is effective for patients with gastrointestinal stromal tumors who have failed to respond to treatment with imatinib and sunitinib, trial results show.

Regorafenib phase III results strongly support use in GIST Posted: 28 Nov 2012 04:00 PM PST Regorafenib is effective for patients with gastrointestinal stromal tumors who have failed to respond to treatment with imatinib and sunitinib, trial results show.

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iPhone Medical News

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Ward Round Picture Quiz | Medical App Review Posted: 27 Nov 2012 11:26 PM PST Ward Round Picture Quiz is a medical gamification project by Guerilla Tea.  Ward Round Picture Quiz a visual diagnosis quiz app that is packaged in an easy to use UI with good quality clinical images.   This app is great for medical students, residents, and anyone else interested in how healthcare professionals diagnose patients.  The quizzes are clearly something a medical student or resident could use while waiting for a conference or clinic to start! The clinical content was developed by Adrian Raudaschl, MBChB from Glasgow University in Scotland. Key points Great user interface Good clinical content Challenge your diagnostic skills in a fun way.

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Medical News

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• Bipolarity common in major depressive episode patients
• Suicide ‘a major concern’ in childhood psychosis
• Bipolarity common in major depressive episode patients
• Suicide ‘a major concern’ in childhood psychosis
• Bleeding risk modifies perioperative beta-blocker benefits
• Factors increasing risk for pertussis in children evaluated
• Hemorrhage risk ‘higher than reported’ for AF warfarin users

Bipolarity common in major depressive episode patients Posted: 28 Nov 2012 04:00 PM PST Results from an Egyptian study show that a substantial proportion of patients being treated for a major depressive episode may have underlying bipolarity.

Suicide ‘a major concern’ in childhood psychosis Posted: 28 Nov 2012 04:00 PM PST Children and adolescents with a first episode of psychosis should be monitored closely for suicidal behavior, say researchers who found that more than 12% of such patients attempted suicide over a 24-month period.

Bipolarity common in major depressive episode patients Posted: 28 Nov 2012 04:00 PM PST Results from an Egyptian study show that a substantial proportion of patients being treated for a major depressive episode may have underlying bipolarity.

Suicide ‘a major concern’ in childhood psychosis Posted: 28 Nov 2012 04:00 PM PST Children and adolescents with a first episode of psychosis should be monitored closely for suicidal behavior, say researchers who found that more than 12% of such patients attempted suicide over a 24-month period.

Bleeding risk modifies perioperative beta-blocker benefits Posted: 27 Nov 2012 04:00 PM PST Perioperative use of beta blockers seems to be beneficial unless patients experience heavy bleeding, in which case it may be detrimental, say researchers.

Factors increasing risk for pertussis in children evaluated Posted: 27 Nov 2012 04:00 PM PST Research shows that children with pertussis infection are significantly less likely to have had all five diphtheria, tetanus, and acellular pertussis vaccine doses than uninfected children.

Hemorrhage risk ‘higher than reported’ for AF warfarin users Posted: 27 Nov 2012 04:00 PM PST Real-world findings for atrial fibrillation patients using warfarin point to a significantly higher risk for hemorrhage than reported for clinical trials.

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Medical News

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• Gastritis linked to mood, anxiety disorders
• Digoxin for atrial fibrillation questioned
• Gastritis linked to mood, anxiety disorders
• Polydipsia linked to brain alterations in schizophrenia
• Polydipsia linked to brain alterations in schizophrenia
• Young vascular systems adapt to obesity
• Targeted preventive cardiac screening in US athletes ‘would limit cost’
• Young vascular systems adapt to obesity
• Latest research allays IUD pelvic disease fear
• Simple measures halve ventilator-associated pneumonia
• Latest research allays IUD pelvic disease fear
• Simple measures halve ventilator-associated pneumonia
• Heart failure risk comparable for rheumatoid arthritis drug classes

Gastritis linked to mood, anxiety disorders Posted: 27 Nov 2012 04:00 PM PST Patients with gastritis are at significantly increased risk for mood and anxiety disorders, study results suggest.

Digoxin for atrial fibrillation questioned Posted: 27 Nov 2012 04:00 PM PST Experts are calling into question the widespread use of digoxin for atrial fibrillation, in the wake of findings linking the drug to increased mortality.

Gastritis linked to mood, anxiety disorders Posted: 27 Nov 2012 04:00 PM PST Patients with gastritis are at significantly increased risk for mood and anxiety disorders, study results suggest.

Polydipsia linked to brain alterations in schizophrenia Posted: 27 Nov 2012 04:00 PM PST Psychogenic polydipsia is associated with significantly reduced left insula volume in patients with schizophrenia, researchers report.

Polydipsia linked to brain alterations in schizophrenia Posted: 27 Nov 2012 04:00 PM PST Psychogenic polydipsia is associated with significantly reduced left insula volume in patients with schizophrenia, researchers report.

Young vascular systems adapt to obesity Posted: 26 Nov 2012 04:00 PM PST Researchers have identified physiologic changes in the vascular systems of children that appear to be an adaptive response to obesity.

Targeted preventive cardiac screening in US athletes ‘would limit cost’ Posted: 26 Nov 2012 04:00 PM PST Research published in the Journal of the American College of Cardiology suggests that a national echocardiographic screening program for US athletes would be prohibitively expensive.

Young vascular systems adapt to obesity Posted: 26 Nov 2012 04:00 PM PST Researchers have identified physiologic changes in the vascular systems of children that appear to be an adaptive response to obesity.

Latest research allays IUD pelvic disease fear Posted: 26 Nov 2012 04:00 PM PST The risk for developing pelvic inflammatory disease following an intrauterine device insertion is low, irrespective of whether a woman has been screened beforehand for gonorrhea and Chlamydia, research findings show.

Simple measures halve ventilator-associated pneumonia Posted: 26 Nov 2012 04:00 PM PST Adding a bundle of low-cost interventions to surveillance significantly reduces rates of ventilator-associated pneumonia in adult intensive care units in developing countries, shows an international study.

Latest research allays IUD pelvic disease fear Posted: 26 Nov 2012 04:00 PM PST The risk for developing pelvic inflammatory disease following an intrauterine device insertion is low, irrespective of whether a woman has been screened beforehand for gonorrhea and Chlamydia, research findings show.

Simple measures halve ventilator-associated pneumonia Posted: 26 Nov 2012 04:00 PM PST Adding a bundle of low-cost interventions to surveillance significantly reduces rates of ventilator-associated pneumonia in adult intensive care units in developing countries, shows an international study.

Heart failure risk comparable for rheumatoid arthritis drug classes Posted: 18 Nov 2012 04:00 PM PST Rheumatoid arthritis patients have no greater risk for heart failure with tumor necrosis factor-alpha therapy than with nonbiologic disease-modifying antirheumatic drugs, research suggests.

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