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Personalized asthma strategies needed to tackle comorbidities Posted: 30 Dec 2013 04:00 PM PST Results from a German national health survey indicate that asthma patients with multiple comorbidities are at increased risk for unplanned hospital admissions.

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Poverty, not smoking, linked to COPD mortality Posted: 29 Dec 2013 04:00 PM PST An international study shows that national mortality rates for chronic obstructive pulmonary disease do not correlate well with the prevalence of smoking in low-income countries but do show a strong inverse correlation with wealth.

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Perinatal probiotic supplements do not prevent childhood asthma Posted: 26 Dec 2013 04:00 PM PST There is insufficient evidence to support the use of probiotic supplements during pregnancy or infancy to prevent the development of asthma in infants, Canadian researchers report.

Perinatal probiotic supplements do not prevent childhood asthma Posted: 26 Dec 2013 04:00 PM PST There is insufficient evidence to support the use of probiotic supplements during pregnancy or infancy to prevent the development of asthma in infants, Canadian researchers report.

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Asthma link to mood disorders strengthened Posted: 23 Dec 2013 04:00 PM PST Results from a prospective study support a relationship between asthma in adolescence and future diagnosis of mood disorders.

Asthma link to mood disorders strengthened Posted: 23 Dec 2013 04:00 PM PST Results from a prospective study support a relationship between asthma in adolescence and future diagnosis of mood disorders.

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• Treating depression fails to reverse cognitive deficits in bipolar disorder
• Treating depression fails to reverse cognitive deficits in bipolar disorder
• Schizophrenia brain marker matches genetic risk
• Schizophrenia brain marker matches genetic risk

Treating depression fails to reverse cognitive deficits in bipolar disorder Posted: 23 Dec 2013 04:00 PM PST Successful treatment of depression with total sleep deprivation does not improve neuropsychologic deficits in bipolar patients, despite improving clinical symptoms, Italian researchers report.

Treating depression fails to reverse cognitive deficits in bipolar disorder Posted: 23 Dec 2013 04:00 PM PST Successful treatment of depression with total sleep deprivation does not improve neuropsychologic deficits in bipolar patients, despite improving clinical symptoms, Italian researchers report.

Schizophrenia brain marker matches genetic risk Posted: 23 Dec 2013 04:00 PM PST Polygenic risk for schizophrenia correlates with neural inefficiency in the left dorsolateral prefrontal cortex, say researchers.

Schizophrenia brain marker matches genetic risk Posted: 23 Dec 2013 04:00 PM PST Polygenic risk for schizophrenia correlates with neural inefficiency in the left dorsolateral prefrontal cortex, say researchers.

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• Genotyping strategy could boost celiac screening efficacy
• Duration of common pediatric respiratory infections estimated
• Young women more likely to have negative urodynamics experience
• Older age linked to poor inhaler technique
• Duration of common pediatric respiratory infections estimated
• Low testosterone levels linked to nocturia in men
• Young women more likely to have negative urodynamics experience

Genotyping strategy could boost celiac screening efficacy Posted: 22 Dec 2013 04:00 PM PST Genotyping for human leukocyte antigen followed by biopsy is a sensitive strategy for detecting histopathologic lesions in the close relatives of people with celiac disease, research indicates.

Duration of common pediatric respiratory infections estimated Posted: 22 Dec 2013 04:00 PM PST An international research team has systematically reviewed the literature to formulate up-to-date estimates of the duration of common childhood respiratory tract infections.

Young women more likely to have negative urodynamics experience Posted: 22 Dec 2013 04:00 PM PST Research from the USA suggests that while urodynamic testing is well-tolerated by women on the whole, patients who are younger, or have anxiety or depression may have more negative experiences of the procedure than other patients.

Older age linked to poor inhaler technique Posted: 22 Dec 2013 04:00 PM PST Poor metered dose inhaler technique is common among older patients with asthma and is associated with reduced controller medication adherence, prospective study findings show.

Duration of common pediatric respiratory infections estimated Posted: 22 Dec 2013 04:00 PM PST An international research team has systematically reviewed the literature to formulate up-to-date estimates of the duration of common childhood respiratory tract infections.

Low testosterone levels linked to nocturia in men Posted: 22 Dec 2013 04:00 PM PST Research from South Korea indicates that low testosterone levels are associated with nocturia in men, independent of both age and prostate volume.

Young women more likely to have negative urodynamics experience Posted: 22 Dec 2013 04:00 PM PST Research from the USA suggests that while urodynamic testing is well-tolerated by women on the whole, patients who are younger, or have anxiety or depression may have more negative experiences of the procedure than other patients.

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• Inflammatory burden increased in overweight bipolar disorder patients
• Inflammatory burden increased in overweight bipolar disorder patients
• Further boost for copy number variant role in schizophrenia
• Cycle test reliable for dyspnea evaluation in obese COPD patients
• Further boost for copy number variant role in schizophrenia

Inflammatory burden increased in overweight bipolar disorder patients Posted: 19 Dec 2013 04:00 PM PST Breakdown of the amino acid tryptophan is increased in euthymic, overweight individuals with bipolar disorder, show preliminary results from the BIPFAT study.

Inflammatory burden increased in overweight bipolar disorder patients Posted: 19 Dec 2013 04:00 PM PST Breakdown of the amino acid tryptophan is increased in euthymic, overweight individuals with bipolar disorder, show preliminary results from the BIPFAT study.

Further boost for copy number variant role in schizophrenia Posted: 19 Dec 2013 04:00 PM PST A large study confirms that 11 previously identified copy number variants are likely associated with schizophrenia.

Cycle test reliable for dyspnea evaluation in obese COPD patients Posted: 19 Dec 2013 04:00 PM PST Dyspnea in obese individuals with chronic obstructive pulmonary disease can be evaluated reliably by cycle ergometry as well as a treadmill test, researchers have found.

Further boost for copy number variant role in schizophrenia Posted: 19 Dec 2013 04:00 PM PST A large study confirms that 11 previously identified copy number variants are likely associated with schizophrenia.

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• Shared genetic risk for bipolar disorder and BMI
• Shared genetic risk for bipolar disorder and BMI
• Neurocognitive abnormalities ‘fundamental’ to schizophrenia
• Childhood asthma secondhand smoke education vital
• Neurocognitive abnormalities ‘fundamental’ to schizophrenia

Shared genetic risk for bipolar disorder and BMI Posted: 18 Dec 2013 04:00 PM PST Researchers have found a positive association in the heritability of bipolar disorder and body mass index, supporting the theory that there is some interaction in the genetic mechanisms underlying these two traits.

Shared genetic risk for bipolar disorder and BMI Posted: 18 Dec 2013 04:00 PM PST Researchers have found a positive association in the heritability of bipolar disorder and body mass index, supporting the theory that there is some interaction in the genetic mechanisms underlying these two traits.

Neurocognitive abnormalities ‘fundamental’ to schizophrenia Posted: 18 Dec 2013 04:00 PM PST Rare copy-number variants that confer a high risk for schizophrenia or autism are associated with impaired cognition in carriers without psychiatric disorders, researchers report in Nature.

Childhood asthma secondhand smoke education vital Posted: 18 Dec 2013 04:00 PM PST A US study has found that smokers caring for children with asthma often underestimate levels of secondhand smoke exposure.

Neurocognitive abnormalities ‘fundamental’ to schizophrenia Posted: 18 Dec 2013 04:00 PM PST Rare copy-number variants that confer a high risk for schizophrenia or autism are associated with impaired cognition in carriers without psychiatric disorders, researchers report in Nature.

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• Diet may not fully explain cardiometabolic problems in bipolar disorder
• Head injuries increase risk for psychiatric disorders
• Diet may not fully explain cardiometabolic problems in bipolar disorder
• Head injuries increase risk for psychiatric disorders
• COPD undertreatment widespread
• Hispanic mortality paradox found in RA patients
• Diet may not fully explain cardiometabolic problems in bipolar disorder
• Head injuries increase risk for psychiatric disorders
• Cardiovascular disease in asthma needs attention

Diet may not fully explain cardiometabolic problems in bipolar disorder Posted: 17 Dec 2013 04:00 PM PST The diet of patients with bipolar disorder or schizophrenia seems to be no worse than that of mentally healthy people, a study suggests.

Head injuries increase risk for psychiatric disorders Posted: 17 Dec 2013 04:00 PM PST A Danish study of a large cohort of individuals who presented at hospital with head injuries has found that they were at increased risk for later developing schizophrenia, bipolar disorder, depression, and organic mental disorders.

Diet may not fully explain cardiometabolic problems in bipolar disorder Posted: 17 Dec 2013 04:00 PM PST The diet of patients with bipolar disorder or schizophrenia seems to be no worse than that of mentally healthy people, a study suggests.

Head injuries increase risk for psychiatric disorders Posted: 17 Dec 2013 04:00 PM PST A Danish study of a large cohort of individuals who presented at hospital with head injuries has found that they were at increased risk for later developing schizophrenia, bipolar disorder, depression, and organic mental disorders.

COPD undertreatment widespread Posted: 17 Dec 2013 04:00 PM PST A study has shown that undertreatment of chronic obstructive pulmonary disease is highly prevalent.

Hispanic mortality paradox found in RA patients Posted: 17 Dec 2013 04:00 PM PST The so-called "Hispanic survival paradox" has been found to extend to patients with rheumatoid arthritis, whereby Hispanic people with the condition tend have more severe symptoms but equivalent mortality to non-Hispanic White individuals.

Diet may not fully explain cardiometabolic problems in bipolar disorder Posted: 17 Dec 2013 04:00 PM PST The diet of patients with bipolar disorder or schizophrenia seems to be no worse than that of mentally healthy people, a study suggests.

Head injuries increase risk for psychiatric disorders Posted: 17 Dec 2013 04:00 PM PST A Danish study of a large cohort of individuals who presented at hospital with head injuries has found that they were at increased risk for later developing schizophrenia, bipolar disorder, depression, and organic mental disorders.

Cardiovascular disease in asthma needs attention Posted: 16 Dec 2013 04:00 PM PST Researchers say that there should be a greater emphasis on preventing cardiovascular disease in people with asthma after finding that it was the leading cause of death in hospitalized asthma patients.

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• Diabetes blamed for brain neurochemical abnormalities in bipolar disorder
• Diabetes blamed for brain neurochemical abnormalities in bipolar disorder
• Unexpected toxicity of pazopanib/pemetrexed in NSCLC halts study
• Selenium fails to protect NSCLC patients against second primary tumors
• Unexpected toxicity of pazopanib/pemetrexed in NSCLC halts study
• Selenium fails to protect NSCLC patients against second primary tumors
• Diabetes blamed for brain neurochemical abnormalities in bipolar disorder
• Rich club disconnectivity may be ‘core’ schizophrenia feature
• Rich club disconnectivity may be ‘core’ schizophrenia feature

Diabetes blamed for brain neurochemical abnormalities in bipolar disorder Posted: 16 Dec 2013 04:00 PM PST Diabetes may underlie some of the neurochemical abnormalities observed in the brains of patients with bipolar disorder, say researchers.

Diabetes blamed for brain neurochemical abnormalities in bipolar disorder Posted: 16 Dec 2013 04:00 PM PST Diabetes may underlie some of the neurochemical abnormalities observed in the brains of patients with bipolar disorder, say researchers.

Unexpected toxicity of pazopanib/pemetrexed in NSCLC halts study Posted: 16 Dec 2013 04:00 PM PST A phase II study comparing first-line combination pazopanib/pemetrexed chemotherapy with the standard cisplatin/pemetrexed treatment in non-small-cell lung cancer was terminated early owing to an increased frequency of adverse events in the experimental arm.

Selenium fails to protect NSCLC patients against second primary tumors Posted: 16 Dec 2013 04:00 PM PST Selenium supplementation does not reduce the risk for second primary tumors in patients with resected non–small-cell lung cancer, researchers say.

Unexpected toxicity of pazopanib/pemetrexed in NSCLC halts study Posted: 16 Dec 2013 04:00 PM PST A phase II study comparing first-line combination pazopanib/pemetrexed chemotherapy with the standard cisplatin/pemetrexed treatment in non-small-cell lung cancer was terminated early owing to an increased frequency of adverse events in the experimental arm.

Selenium fails to protect NSCLC patients against second primary tumors Posted: 16 Dec 2013 04:00 PM PST Selenium supplementation does not reduce the risk for second primary tumors in patients with resected non–small-cell lung cancer, researchers say.

Diabetes blamed for brain neurochemical abnormalities in bipolar disorder Posted: 16 Dec 2013 04:00 PM PST Diabetes may underlie some of the neurochemical abnormalities observed in the brains of patients with bipolar disorder, say researchers.

Rich club disconnectivity may be ‘core’ schizophrenia feature Posted: 16 Dec 2013 04:00 PM PST The impaired "rich club" connectivity observed in the brains of patients with schizophrenia is also present in their unaffected siblings, report researchers.

Rich club disconnectivity may be ‘core’ schizophrenia feature Posted: 16 Dec 2013 04:00 PM PST The impaired "rich club" connectivity observed in the brains of patients with schizophrenia is also present in their unaffected siblings, report researchers.

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• ‘Window for intervention’ to forestall hypertensive cognitive decline
• Interactive booklet boosts parents’ RTI confidence
• Chest wall resection effective for recurrent mesothelioma
• Erlotinib ‘dose-to-rash’ strategy effective in advanced NSCLC
• Chest wall resection effective for recurrent mesothelioma
• Erlotinib ‘dose-to-rash’ strategy effective in advanced NSCLC
• Interactive booklet boosts parents’ RTI confidence
• Fat mass not linked to lung function in children with asthma
• Incision technique shows potential for bladder neck contracture
• Potential dual benefits to tackling LUTS progression risk factors

‘Window for intervention’ to forestall hypertensive cognitive decline Posted: 15 Dec 2013 04:00 PM PST Newly diagnosed hypertension is predictive of cognitive decline in middle-aged individuals and is worse in those with poorly controlled blood pressure, Dutch researchers have found.

Interactive booklet boosts parents’ RTI confidence Posted: 15 Dec 2013 04:00 PM PST An interactive booklet given to parents in primary care can help them to be more knowledgeable and feel more confident about when and when not to consult a doctor for their child's respiratory tract infections.

Chest wall resection effective for recurrent mesothelioma Posted: 15 Dec 2013 04:00 PM PST Salvage chest wall resection could lengthen survival in patients with isolated chest wall recurrence of malignant pleural mesothelioma, research indicates.

Erlotinib ‘dose-to-rash’ strategy effective in advanced NSCLC Posted: 15 Dec 2013 04:00 PM PST Erlotinib as first-line therapy in patients with advanced non-small-cell lung cancer is equivalent to chemotherapy with regard to overall survival, an "all-comers" phase II trial has shown.

Chest wall resection effective for recurrent mesothelioma Posted: 15 Dec 2013 04:00 PM PST Salvage chest wall resection could lengthen survival in patients with isolated chest wall recurrence of malignant pleural mesothelioma, research indicates.

Erlotinib ‘dose-to-rash’ strategy effective in advanced NSCLC Posted: 15 Dec 2013 04:00 PM PST Erlotinib as first-line therapy in patients with advanced non-small-cell lung cancer is equivalent to chemotherapy with regard to overall survival, an "all-comers" phase II trial has shown.

Interactive booklet boosts parents’ RTI confidence Posted: 15 Dec 2013 04:00 PM PST An interactive booklet given to parents in primary care can help them to be more knowledgeable and feel more confident about when and when not to consult a doctor for their child's respiratory tract infections.

Fat mass not linked to lung function in children with asthma Posted: 15 Dec 2013 04:00 PM PST A study suggests that the relationship between body mass and lung function in children with asthma is more nuanced than previously thought.

Incision technique shows potential for bladder neck contracture Posted: 15 Dec 2013 04:00 PM PST A US team reports that deep lateral transurethral incisions are a promising technique for the treatment of recurrent bladder neck contracture in men following prostate surgery.

Potential dual benefits to tackling LUTS progression risk factors Posted: 15 Dec 2013 04:00 PM PST Research shows that several risk factors associated with Type 2 diabetes and cardiovascular disease also predict the progression of storage and voiding lower urinary tract symptoms in men, suggesting that targeting these could have multiple benefits.

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