| Gouty tophi predict cardiovascular remodeling Posted: 15 Jan 2014 04:00 PM PST Research shows that the severity of gout, rather than uric acid level, is significantly associated with changes in left ventricular diastolic function and left atrial volume.  |
| Obesity interferes with blood pressure control Posted: 12 Jan 2014 04:00 PM PST Patients who are overweight or obese have a high risk for uncontrolled blood pressure, despite often taking multiple antihypertensive agents, say researchers.  |
| Diabetes blamed for brain neurochemical abnormalities in bipolar disorder Posted: 16 Dec 2013 04:00 PM PST Diabetes may underlie some of the neurochemical abnormalities observed in the brains of patients with bipolar disorder, say researchers.  |
| Type 2 diabetes cytokine elevation places teeth at risk Posted: 20 Nov 2013 04:00 PM PST Scientists have detected significant differences in the cytokine and chemokine make up of gingival crevicular fluid taken from chronic periodontitis patients with uncontrolled Type 2 diabetes and those without.  |
| Ambulatory BP best for assessing diabetes CV risk Posted: 03 Nov 2013 04:00 PM PST Ambulatory blood pressure monitoring should be used to monitor patients with Type 2 diabetes who have a high risk for developing cardiovascular complications, say researchers.  |
| <i>BRCA1/2 </i>mutations may alter endometrial, ovarian function Posted: 21 Oct 2013 05:00 PM PDT Scientists have detected significant differences in endometrial thickness and hormone levels in women with and without BRCA1/2 mutations that may play a role in cancer susceptibility or development.  |
| Cardiometabolic risk high for schizophrenia patients Posted: 16 Oct 2013 05:00 PM PDT The risk for abdominal obesity may be increased as much as fourfold for patients with multi-episode schizophrenia compared with the rest of the population, reveal findings from a meta-analysis.  |
| DiaRem score predicts diabetes remission after gastric bypass Posted: 19 Sep 2013 05:00 PM PDT A new scoring system offers a "scientifically valid" way of predicting the 5-year likelihood for diabetes remission in patients undergoing gastric bypass surgery, say the researchers who developed the score.  |
| Dual-pronged approach to diabetes and COPD needed Posted: 16 Sep 2013 05:00 PM PDT Researchers from the USA have found that patients with diabetes and a history of smoking have significantly impaired lung function, even in the absence of overt chronic obstructive pulmonary disease.  |
| Gene variations predict breast cancer sleep disturbance Posted: 15 Sep 2013 05:00 PM PDT Researchers have identified cytokine gene variations in women with breast cancer that may help to identify those at increased risk for sleep disturbance following surgery.  |
| Milestone for ischemic preconditioning Posted: 20 Aug 2013 05:00 PM PDT A randomized, controlled trial provides the first strong evidence that remote ischemic preconditioning can reduce mortality among patients undergoing coronary artery bypass graft surgery.  |
| Diabetes plus obesity increases RCC recurrence risk Posted: 12 Aug 2013 05:00 PM PDT Patients with renal cell carcinoma are at increased risk for recurrence following surgery if they also have Type 2 diabetes, a retrospective analysis shows.  |
| Multiple BP components give better vascular risk picture Posted: 04 Aug 2013 05:00 PM PDT Considering just one component of blood pressure may give an incomplete picture of a person's cardiovascular risk, study findings suggest.  |
| Diabetes worsens schizophrenia cognitive impairment Posted: 17 Jul 2013 05:00 PM PDT Diabetes exacerbates cognitive impairment in patients with schizophrenia, particularly in immediate memory and attention, say researchers.  |
| Pulmonary effects leave cardiac red herring in COPD, emphysema Posted: 19 Jun 2013 05:00 PM PDT US researchers have found evidence that impaired left ventricular filling in patients with chronic obstructive pulmonary disease and emphysema is caused by reduced left ventricular preload due to upstream pulmonary causes, as opposed to intrinsic diastolic dysfunction.  |
| Biventricular pacing best in atrioventricular block patients Posted: 28 Apr 2013 05:00 PM PDT Use of biventricular rather than conventional right ventricular pacing results in better clinical outcomes in patients who have heart failure with atrioventricular block and left ventricular systolic dysfunction, show the results of BLOCK HF.  |
| Protective ventilation strategy offers post-op lung benefits Posted: 24 Apr 2013 05:00 PM PDT Patients who receive a lung-protective ventilation strategy during abdominal surgery benefit from better respiratory function and fewer signs of infection afterward, a study finds.  |
| Tamoxifen breast changes predict survival Posted: 22 Apr 2013 05:00 PM PDT Women with breast cancer who experience a tamoxifen-related decrease in mammographic density have significantly better survival than patients whose breast density is unaffected by the agent, suggest study findings.  |
| Simple assessment predicts need for reintubation Posted: 17 Apr 2013 05:00 PM PDT A simple scoring system allows anesthesiologists to reliably predict severe postoperative respiratory complications, researchers report in Anesthesiology.  |
| ‘Breathprint’ offers efficient diagnosis of heart failure Posted: 16 Apr 2013 05:00 PM PDT Analysis of a single exhaled breath of air or "breathprint" can be used to quickly diagnose patients with heart failure, shows research.  |
| Genotoxic properties of nitrous oxide revealed yet again Posted: 10 Apr 2013 05:00 PM PDT Nitrous oxide administered to adult patients undergoing major elective open colorectal surgery is associated with DNA damage in peripheral leukocytes, a study finds  |
| Radiotherapy ‘does not preclude’ immediate breast reconstruction Posted: 08 Apr 2013 05:00 PM PDT Women who receive radiotherapy after free-flap breast reconstruction are no more likely to require revision surgery than those who do not, say US researchers who believe immediate autologous surgery is feasible in this group.  |
| Ultrasound enables fuss-free lumbar puncture Posted: 04 Apr 2013 05:00 PM PDT Use of ultrasound imaging helps to minimize adjustments, failures, and trauma during lumbar puncture or epidural catheterization, conclude the authors of a systematic review and meta-analysis.  |
| Awareness during general anesthesia ‘may be underestimated’ Posted: 21 Mar 2013 05:00 PM PDT There is a low rate of accidental awareness during general anesthesia in the UK, survey results show.  |
| Colonoscopy may be more risky under anesthesia Posted: 14 Mar 2013 05:00 PM PDT The risk for aspiration and other complications related to colonoscopy may be increased if the procedure is performed under propofol-induced deep sedation, US study findings suggest.  |
| EEG patterns track propofol effects Posted: 06 Mar 2013 04:00 PM PST Researchers have identified electroencephalogram signatures of changes in consciousness caused by propofol.  |
| Heed the fire triangle for safe electrocautery Posted: 04 Mar 2013 04:00 PM PST Most fires in the operating room are caused by electrocautery, according to a US review of surgical malpractice claims.  |
| Epidural pain relief best after open colorectal surgery Posted: 28 Feb 2013 04:00 PM PST Epidural analgesia provides more pain relief than continuous wound filtration with local anesthetic in patients undergoing fast-track open colorectal surgery, research shows.  |
| Symptom severity, hospice patient distress not necessarily linked Posted: 19 Feb 2013 04:00 PM PST End-stage heart failure patients being treated in hospices have multiple symptoms with potential to cause distress, indicate US study findings.  |
| Copper depletion may prevent breast cancer recurrence Posted: 17 Feb 2013 04:00 PM PST Early trial findings suggest that copper depletion may promote tumor dormancy in patients at high risk for recurrent breast cancer.  |
| Arrhythmia may confound heart failure treatment Posted: 10 Feb 2013 04:00 PM PST Meta-analysis findings question whether beta-blocker treatment remains effective in patients who have heart failure with reduced left ventricular ejection fraction if they also have atrial fibrillation.  |
| Breast cancer genes modify age at menopause Posted: 03 Feb 2013 04:00 PM PST Women with the BRCA1 or BRCA2 mutation begin menopause at a significantly younger median age than noncarriers, US researchers warn.  |
| Dual renin angiotensin system blockade: too many cons Posted: 03 Feb 2013 04:00 PM PST Any benefit of dual blockade of the renin angiotensin system is limited to its effects on surrogate endpoints, and outweighed by an excessive risk for adverse events such as hypotension, hyperkalemia, and renal failure, argue hypertension experts.  |
| MRI ‘good accuracy’ for detecting residual breast cancer Posted: 20 Jan 2013 04:00 PM PST Magnetic resonance imaging is superior to mammography for the detection of residual breast cancer after neoadjuvant chemotherapy, research confirms.  |
| Poor awareness, misunderstanding hinder palliative care for heart failure Posted: 01 Jan 2013 04:00 PM PST A lack of awareness among heart failure patients prevents them accessing palliative care services during the late stages of their disease, indicate US study findings.  |
| Diuretic-based antihypertensive therapy touted for obese Posted: 23 Dec 2012 04:00 PM PST Diuretic-based antihypertensive regimens may be preferable to calcium channel blocker-based therapy in patients who are obese, suggest researchers writing in The Lancet.  |
| Diuretic-based antihypertensive therapy touted for obese Posted: 23 Dec 2012 04:00 PM PST Diuretic-based antihypertensive regimens may be preferable to calcium channel blocker-based therapy in patients who are obese, suggest researchers writing in The Lancet.  |
| Lapatinib benefits found for HER2-positive early-stage patients Posted: 16 Dec 2012 04:00 PM PST Women with early-stage, HER2-positive breast cancer who are unable to use trastuzumab may benefit from adjuvant lapatinib treatment, suggest phase III trial findings published in Lancet Oncology.  |
| <sup>18</sup>FDG–PET–CT improves breast cancer staging Posted: 16 Dec 2012 04:00 PM PST A prospective study has shown fluorodeoxyglucose positron emission tomography/computed tomography to be a powerful tool for the detection of nodal and distant metastatic disease in patients with breast cancer.  |
| ATLAS holds up 10-year tamoxifen regime Posted: 09 Dec 2012 04:00 PM PST Results from the ATLAS study indicate that women with estrogen receptor-positive breast cancer should consider taking tamoxifen for up to 10 years after diagnosis.  |
| 'Puppy fat' notion dismissed Posted: 04 May 2006 05:00 PM PDT The concept that "puppy fat" will disappear as a child grows up is a myth, suggests research that shows children who are overweight or obese when they enter secondary school rarely slim down by the time they leave.  |
| Folic acid linked to IVF twin birth rate Posted: 04 May 2006 05:00 PM PDT Fortifying flour with folic acid could boost the number of twin births among women who conceive through in vitro fertilisation, study findings indicate.  |
| Sunscreen labels to be overhauled Posted: 04 May 2006 05:00 PM PDT Sunscreens carry misleading labelling, claims the European Commission, which wants manufacturers to adhere to a standardised, simple system.  |
| Roasted vegetables pose tooth erosion risk Posted: 04 May 2006 05:00 PM PDT Eating oven-roasted vegetables may be a popular way of incorporating the recommended five portions of fruit and vegetables into the diet, but the acidity of the dish is hazardous for the teeth, say researchers.  |
| Newborns with jaundice 'develop normally' Posted: 03 May 2006 05:00 PM PDT Parents and clinicians may be reassured by US study findings that show newborns with jaundice develop normally, providing proper treatment is given.  |
| Hopes raised for preventative breast cancer drug Posted: 03 May 2006 05:00 PM PDT A novel drug has shown such promise in preventing secondary breast cancer in premenopausal women that researchers are calling for a trial into the value of the compound as a prophylaxis for young women at high risk of the disease.  |
| Mouse model sheds light on autism Posted: 03 May 2006 05:00 PM PDT Scientists in the USA have genetically engineered mice to display characteristics of autism spectrum disorders that could potentially boost understanding of the behavioural condition.  |
| Stent promise for arterial leg disease Posted: 03 May 2006 05:00 PM PDT Patients with arterial disease in the legs may benefit more from insertion of flexible nickel–titanium stents than from standard angioplasty surgery, research findings suggest.  |
| Epileptics need warning over death risk Posted: 02 May 2006 05:00 PM PDT Neurologists should tell epilepsy patients of the increased risk of mortality associated with seizures, UK experts warned today.  |
| Middle-aged Americans less healthy than English Posted: 02 May 2006 05:00 PM PDT The health of middle-aged people in England is much better than that of their counterparts in the USA, say investigators, who remain uncertain as to why this is the case.  |
