Medical News

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• Age critical for VKA dosing in children
• Anesthesia choices affect pre-eclamptic women’s stroke risk after cesarean
• Post-thrombolysis hemorrhage scores of ‘limited’ value
• Adalimumab effective for hand and foot psoriasis
• Diabetes linked to poor prognosis in breast cancer survivors
• Lipoprotein subclasses do not predict CVD risk in FH and FCH patients
• Continued statin use post-MI can still be improved
• HbA1c extremes linked to increased cardiovascular event risk in diabetics
• Moderate increases in alcohol intake reduce Type 2 diabetes risk in men
• Cardioprotective ‘polypill’ trial begins
• PCI best reperfusion strategy in elderly STEMI patients
• Diabetes linked to poor prognosis in breast cancer survivors
• Anesthesia choices affect pre-eclamptic women’s stroke risk after cesarean
• Simple risk index predicts postoperative pulmonary complications
• Prehospital intubation cleared of raising pneumonia risk
• Safety initiative cuts errors in patient-controlled analgesia

Age critical for VKA dosing in children Posted: 06 Jan 2011 04:00 PM PST Age is the most important variable in determining vitamin K antagonist dose in children, whereas genetic polymorphisms have very little impact, study findings indicate.

Anesthesia choices affect pre-eclamptic women’s stroke risk after cesarean Posted: 06 Jan 2011 04:00 PM PST Women with pre-eclampsia who undergo cesarean section are less likely to suffer a stroke during the subsequent 6 years if they are given neuraxial, rather than general, anesthesia, research suggests.

Post-thrombolysis hemorrhage scores of ‘limited’ value Posted: 06 Jan 2011 04:00 PM PST Two scores developed to predict intracerebral hemorrhage in stroke patients treated with tissue plasminogen activator prove to have poor discriminatory value in a validation cohort.

Adalimumab effective for hand and foot psoriasis Posted: 06 Jan 2011 04:00 PM PST Adalimumab is an effective and well tolerated treatment for chronic plaque psoriasis of the hands and feet, report researchers who found efficacy was maintained for at least 28 weeks.

Diabetes linked to poor prognosis in breast cancer survivors Posted: 06 Jan 2011 04:00 PM PST Chronic hyperglycemia, as indicated by elevated glycated hemoglobin levels, is independently associated with an increased risk for all-cause mortality in breast cancer survivors, US researchers report.

Lipoprotein subclasses do not predict CVD risk in FH and FCH patients Posted: 06 Jan 2011 04:00 PM PST Patients with familial hypercholesterolemia and familial combined hyperlipidemia have an increased atherosclerotic burden in comparison with healthy controls, but lipoprotein subclasses do not substantially contribute to the development of carotid atherosclerosis in these patients, report Spanish researchers.

Continued statin use post-MI can still be improved Posted: 06 Jan 2011 04:00 PM PST Although statin use post-myocardial infarction has increased considerably in the UK, researchers say that long-term adherence in those from lower socio-economic groups, smokers, and older patients can still be improved.

HbA1c extremes linked to increased cardiovascular event risk in diabetics Posted: 06 Jan 2011 04:00 PM PST Researchers report that patients with Type 2 diabetes who achieve a very low glycated hemoglobin level or fail to reduce their levels sufficiently are at increased risk for cardiovascular events.

Moderate increases in alcohol intake reduce Type 2 diabetes risk in men Posted: 06 Jan 2011 04:00 PM PST Small daily increases in alcohol intake are associated with decreased risk for Type 2 diabetes in men who are initially rare or light drinkers, show study findings.

Cardioprotective ‘polypill’ trial begins Posted: 06 Jan 2011 04:00 PM PST A phase III trial to assess the effect of a four-component "polypill" on primary prevention of ischemic heart disease and stroke in individuals aged 50 years and older begins in the UK this week, the investigators have announced.

PCI best reperfusion strategy in elderly STEMI patients Posted: 06 Jan 2011 04:00 PM PST Myocardial reperfusion using primary percutaneous coronary intervention may produce better short-term outcomes than fibrinolysis in ST-elevation myocardial infarction patients aged 75 years or older, researchers report.

Diabetes linked to poor prognosis in breast cancer survivors Posted: 06 Jan 2011 04:00 PM PST Chronic hyperglycemia, as indicated by elevated glycated hemoglobin levels, is independently associated with an increased risk for all-cause mortality in breast cancer survivors, US researchers report.

Anesthesia choices affect pre-eclamptic women’s stroke risk after cesarean Posted: 06 Jan 2011 04:00 PM PST Women with pre-eclampsia who undergo cesarean section are less likely to suffer a stroke during the subsequent 6 years if they are given neuraxial, rather than general, anesthesia, research suggests.

Simple risk index predicts postoperative pulmonary complications Posted: 06 Jan 2011 04:00 PM PST A straightforward risk score based on easily available clinical variables appears to be highly accurate at identifying patients at risk for postoperative pulmonary complications, say the score's developers.

Prehospital intubation cleared of raising pneumonia risk Posted: 06 Jan 2011 04:00 PM PST The risk for ventilator-associated pneumonia in trauma patients is not influenced by whether patients undergo intubation before or on arrival at hospital, shows US research.

Safety initiative cuts errors in patient-controlled analgesia Posted: 06 Jan 2011 04:00 PM PST A comprehensive safety program can markedly reduce errors relating to patient-controlled analgesia, say researchers.

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