Medical News

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• Adolescents at high psychosis risk exhibit emotion recognition deficits
• Patterns of Axis I comorbidity differ by age in bipolar patients
• Low carnitine levels linked to fatigue severity in chronic hepatitis C patients
• CT technique detects more post-TKA thrombosis than traditional methods
• Type 2 diabetics with NSTE-ACS have antiplatelet-resistant thrombi
• sCAD begins in the outer artery wall layers
• Genetic screening identifies most children with autosomal dominant hypercholesterolemia
• Multiple risk factors should be considered for CV risk stratification
• Type 2 diabetics with NSTE-ACS have antiplatelet-resistant thrombi
• hsCRP may differentiate HNF1A-MODY from Type 2 diabetes
• Coronary calcium scanning aids long-term CV risk factor control
• Half of AF cases preventable through better risk-factor control
• Statins reduce relapse rates after prostate radiotherapy
• Cancer recurrence worries affect women differently

Adolescents at high psychosis risk exhibit emotion recognition deficits Posted: 31 Mar 2011 05:00 PM PDT Adolescents at ultra-high risk for psychosis often misattribute facial expressions of emotion, with an increased degree of misattribution associated with reduced inhibitory control, research shows.

Patterns of Axis I comorbidity differ by age in bipolar patients Posted: 31 Mar 2011 05:00 PM PDT Results from an Italian study show that patterns of Axis I comorbidity and substance abuse differ by age in patients with bipolar disorder.

Low carnitine levels linked to fatigue severity in chronic hepatitis C patients Posted: 31 Mar 2011 05:00 PM PDT Study findings suggest that plasma carnitine levels are inversely correlated with fatigue severity in patients with chronic hepatitis C.

CT technique detects more post-TKA thrombosis than traditional methods Posted: 30 Mar 2011 05:00 PM PDT Multislice computed tomography is more sensitive than conventional techniques for the detection of deep vein thrombosis and pulmonary arterial thrombosis in patients who have undergone total knee arthroplasty, study findings indicate.

Type 2 diabetics with NSTE-ACS have antiplatelet-resistant thrombi Posted: 30 Mar 2011 05:00 PM PDT Patients with Type 2 diabetes have a greater thrombus burden after experiencing non-ST elevation acute coronary syndrome than nondiabetics, say UK researchers.

sCAD begins in the outer artery wall layers Posted: 30 Mar 2011 05:00 PM PDT Pathologic changes in the arterial walls of patients with spontaneous cervical artery dissection are confined mainly to the outer layers, shows research published in the journal Neurology.

Genetic screening identifies most children with autosomal dominant hypercholesterolemia Posted: 30 Mar 2011 05:00 PM PDT Study findings indicate that most of the genes underlying autosomal dominant hypercholesterolemia are now known, suggesting that genetic testing can successfully identify the vast majority of children with this condition.

Multiple risk factors should be considered for CV risk stratification Posted: 30 Mar 2011 05:00 PM PDT Cardiovascular risk assessment should focus on multiple risk factors rather than only one, say researchers who found that harmful increases in femoral and carotid intima media thickness were associated with increases in the number of risk factors in asymptomatic young adults.

Type 2 diabetics with NSTE-ACS have antiplatelet-resistant thrombi Posted: 30 Mar 2011 05:00 PM PDT Patients with Type 2 diabetes have a greater thrombus burden after experiencing non-ST elevation acute coronary syndrome than nondiabetics, say UK researchers.

hsCRP may differentiate HNF1A-MODY from Type 2 diabetes Posted: 30 Mar 2011 05:00 PM PDT Findings from a UK study indicate that patients with maturity onset diabetes of the young, resulting from HNF1A mutations, have lower levels of high-sensitivity C-reactive protein than patients with other forms of diabetes.

Coronary calcium scanning aids long-term CV risk factor control Posted: 30 Mar 2011 05:00 PM PDT The use of coronary artery calcium scanning in asymptomatic individuals is associated with improved risk-factor control as compared with usual care, a randomized trial has found.

Half of AF cases preventable through better risk-factor control Posted: 30 Mar 2011 05:00 PM PDT The burden of atrial fibrillation could be halved through optimal control of cardiovascular risk factors, a US study suggests.

Statins reduce relapse rates after prostate radiotherapy Posted: 28 Mar 2011 05:00 PM PDT Statins may reduce the likelihood of relapse after radiotherapy for prostate cancer, indicate US study results.

Cancer recurrence worries affect women differently Posted: 27 Mar 2011 05:00 PM PDT Factors unrelated to recurrence risk define women's tendency to worry about breast cancer recurrence, say US researchers.

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Medical News

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• Exhaled biomarkers show limited value in gauging asthma control
• Eating disorders common in women with bipolar I disorder
• Substance abuse linked to involuntary hospitalization in FEP patients
• Acute statin therapy improves survival after ischemic stroke
• Response inhibition deficits may indicate familial liability for psychotic BD I
• Airport body scanners pose ‘trivial’ cancer risk
• Acute statin therapy improves survival after ischemic stroke
• Obesity linked to cardiac dysfunction
• Diabetes/hyperglycemia risk loci linked with lipoprotein traits
• Autonomic imbalance found in comorbid diabetes/hypertension
• Lowering the troponin I diagnostic threshold improves ACS outcomes
• Antidepressant drug adherence linked to reduced MI risk

Exhaled biomarkers show limited value in gauging asthma control Posted: 30 Mar 2011 05:00 PM PDT Assessment of gas and pH levels in exhaled breath may offer a new way to gauge asthma control, according to researchers writing in the journal Respiratory Medicine.

Eating disorders common in women with bipolar I disorder Posted: 30 Mar 2011 05:00 PM PDT Eating disorders are common in women with bipolar I disorder and are associated with increased severity of the mood condition, say researchers.

Substance abuse linked to involuntary hospitalization in FEP patients Posted: 30 Mar 2011 05:00 PM PDT Substance abuse is associated with an increased risk for involuntary hospitalization in patients with first-episode psychosis, study results show.

Acute statin therapy improves survival after ischemic stroke Posted: 29 Mar 2011 05:00 PM PDT Prestroke and acute poststroke statin therapy can significantly improve survival rates in ischemic stroke patients, show study results.

Response inhibition deficits may indicate familial liability for psychotic BD I Posted: 29 Mar 2011 05:00 PM PDT Patients with bipolar I disorder who have a history of psychotic symptoms and their unaffected first-degree relatives exhibit impairments in response inhibition, researchers have found.

Airport body scanners pose ‘trivial’ cancer risk Posted: 29 Mar 2011 05:00 PM PDT US researchers estimate that the risk for cancer associated with airport body scanners is extremely small, even among frequent fliers.

Acute statin therapy improves survival after ischemic stroke Posted: 29 Mar 2011 05:00 PM PDT Prestroke and acute poststroke statin therapy can significantly improve survival rates in ischemic stroke patients, show study results.

Obesity linked to cardiac dysfunction Posted: 29 Mar 2011 05:00 PM PDT Results from a Swedish study indicate that obesity is significantly associated with cardiac dysfunction.

Diabetes/hyperglycemia risk loci linked with lipoprotein traits Posted: 29 Mar 2011 05:00 PM PDT Several genetic risk loci for Type 2 diabetes and hyperglycemia are also associated with lipoprotein traits, an international research team has shown.

Autonomic imbalance found in comorbid diabetes/hypertension Posted: 29 Mar 2011 05:00 PM PDT The presence of Type 2 diabetes in individuals with treatment-resistant hypertension is associated with autonomic imbalance, lower adiponectin levels, and higher body mass index, a Brazilian study has found.

Lowering the troponin I diagnostic threshold improves ACS outcomes Posted: 29 Mar 2011 05:00 PM PDT The use of a sensitive troponin I assay in patients admitted to hospital with suspected acute coronary syndrome can improve diagnosis and clinical outcomes, study findings suggest.

Antidepressant drug adherence linked to reduced MI risk Posted: 29 Mar 2011 05:00 PM PDT Results from a large US study indicate that adherence to 12 weeks of continuous antidepressant pharmacotherapy may reduce the risk for myocardial infarction in depressed patients with no history of cardiac disease.

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Medical News

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• ‘CAT’ score helps monitor response to pulmonary rehabilitation
• Language lateralization reduced in first-episode schizophrenia
• Celiac disease screening program may be feasible
• Targeting novel protein may improve thrombolysis
• Post-marketing study CAS outcomes a poor reflection of reality
• Statins reduce relapse rates after prostate radiotherapy
• Researchers recommend CAC scanning for cardiac management
• Long-term obesity increases mortality risk
• Sulfonylurea use may increase risk for hospitalization with MI
• IDF statement supports bariatric surgery for eligible diabetes patients
• AF inducible after SVT ablation
• Physical, sexual activity may raise acute cardiac events risk

‘CAT’ score helps monitor response to pulmonary rehabilitation Posted: 29 Mar 2011 05:00 PM PDT The COPD assessment test, a new disease-specific measure of health status, is a simple and valuable tool for assessing response to pulmonary rehabilitation, study findings suggest.

Language lateralization reduced in first-episode schizophrenia Posted: 29 Mar 2011 05:00 PM PDT First-episode, antipsychotic-naïve schizophrenia patients show reduced language lateralization, suggesting that this deficiency is not a result of treatment, say researchers.

Celiac disease screening program may be feasible Posted: 29 Mar 2011 05:00 PM PDT Findings from a US community-based study demonstrate that undiagnosed celiac disease is a readily identifiable and "relatively" common condition in the general population.

Targeting novel protein may improve thrombolysis Posted: 28 Mar 2011 05:00 PM PDT French researchers suggest that protease nexin-1 may be an important regulator of thrombolysis.

Post-marketing study CAS outcomes a poor reflection of reality Posted: 28 Mar 2011 05:00 PM PDT Carotid artery stenting outcomes derived from post-marketing surveillance studies are "unlikely" to reflect outcomes in real-world clinical practice, say researchers.

Statins reduce relapse rates after prostate radiotherapy Posted: 28 Mar 2011 05:00 PM PDT Statins may reduce the likelihood of relapse after radiotherapy for prostate cancer, indicate US study results.

Researchers recommend CAC scanning for cardiac management Posted: 28 Mar 2011 05:00 PM PDT US researchers say that coronary artery calcium scanning can improve cardiac management without incurring significant increases in downstream medical costs.

Long-term obesity increases mortality risk Posted: 28 Mar 2011 05:00 PM PDT The amount of time a person lives with obesity significantly affects their risk for mortality, say researchers.

Sulfonylurea use may increase risk for hospitalization with MI Posted: 28 Mar 2011 05:00 PM PDT Diabetic patients treated with sulfonylureas may be at increased risk for hospitalization with myocardial infarction compared with patients treated with other medications, say researchers.

IDF statement supports bariatric surgery for eligible diabetes patients Posted: 28 Mar 2011 05:00 PM PDT The International Diabetes Federation has released a position statement supporting the use of bariatric surgery to treat diabetes in suitable patients.

AF inducible after SVT ablation Posted: 28 Mar 2011 05:00 PM PDT Study findings show that atrial fibrillation can be induced in more than a quarter of successfully ablated supraventricular tachycardia patients who have no prior history of the atrial arrhythmia.

Physical, sexual activity may raise acute cardiac events risk Posted: 28 Mar 2011 05:00 PM PDT Every episode of physical and sexual activity may increase an individual's immediate risk for myocardial infarction and sudden cardiac death, suggest results from a systematic review and meta-analysis.

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Medical News

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• Many depressive patients fall into ‘soft bipolar spectrum’
• Subjective QoL, psychosocial functioning independent in schizophrenia
• Warfarin therapy feasible for Budd-Chiari Syndrome
• Coiling trumps clipping for unruptured aneurysms in elderly
• Cancer recurrence worries affect women differently
• Non-linear variables are key to successful ovarian cancer prediction
• Low-dose OC relieves menstrual pain in endometriosis
• Non-linear variables are key to successful ovarian cancer prediction
• Contraception advice should be given alongside teratogenic prescriptions
• Just as important for expectant fathers, as expectant mothers, to quit smoking
• ‘Mindfulness’ training could reduce burden of hot flashes
• Lipoprotein(a) levels may identify FH patients at high coronary risk
• CRP plays no part in coronary artery disease
• Link between PCOS and diabetes confirmed
• Proliferative diabetic retinopathy linked to defective heart muscle perfusion
• Conflicts of interest common among CVD guideline development committees

Many depressive patients fall into ‘soft bipolar spectrum’ Posted: 28 Mar 2011 05:00 PM PDT Around 85% of patients who present with depression may show some degree of bipolarity based on the concept of the soft bipolar spectrum, study results show.

Subjective QoL, psychosocial functioning independent in schizophrenia Posted: 28 Mar 2011 05:00 PM PDT Subjective quality of life and psychosocial functioning are independent constructs in schizophrenia and should be assessed separately, results of a study suggest.

Warfarin therapy feasible for Budd-Chiari Syndrome Posted: 27 Mar 2011 05:00 PM PDT Chinese researchers have shown that warfarin may be suitable for the treatment of chronic inferior vena cava thrombosis in patients with Budd-Chiari syndrome.

Coiling trumps clipping for unruptured aneurysms in elderly Posted: 27 Mar 2011 05:00 PM PDT If elderly patients are to undergo treatment of unruptured cerebral aneurysms it should be with endovascular coiling rather than surgical clipping, say researchers.

Cancer recurrence worries affect women differently Posted: 27 Mar 2011 05:00 PM PDT Factors unrelated to recurrence risk define women's tendency to worry about breast cancer recurrence, say US researchers.

Non-linear variables are key to successful ovarian cancer prediction Posted: 27 Mar 2011 05:00 PM PDT Statistical models that use clinical and demographic characteristics to estimate the probability of ovarian cancer can be made more accurate by adjusting for non-linear relationships between key variables, show US study results.

Low-dose OC relieves menstrual pain in endometriosis Posted: 27 Mar 2011 05:00 PM PDT Low-dose oral contraceptives are a possible treatment option for women with primary dysmenorrhea, show results of a randomized controlled trial.

Non-linear variables are key to successful ovarian cancer prediction Posted: 27 Mar 2011 05:00 PM PDT Statistical models that use clinical and demographic characteristics to estimate the probability of ovarian cancer can be made more accurate by adjusting for non-linear relationships between key variables, show US study results.

Contraception advice should be given alongside teratogenic prescriptions Posted: 27 Mar 2011 05:00 PM PDT Study results indicate a need for increased awareness in primary care-specific training of the risks associated with prescribing teratogenic medications, and furthermore, the need for concurrent contraceptive counseling.

Just as important for expectant fathers, as expectant mothers, to quit smoking Posted: 27 Mar 2011 05:00 PM PDT Being exposed to secondhand smoke during pregnancy increases the risk for stillbirth, and the baby being born with a congenital malformation, show study results.

‘Mindfulness’ training could reduce burden of hot flashes Posted: 27 Mar 2011 05:00 PM PDT Mindfulness-based stress reduction training could dramatically reduce the bother and distress menopausal women experience from hot flashes, report US researchers.

Lipoprotein(a) levels may identify FH patients at high coronary risk Posted: 27 Mar 2011 05:00 PM PDT Levels of lipoprotein (Lp)(a) may be an important marker of coronary heart disease risk in patients with familial hypercholesterolemia, say researchers.

CRP plays no part in coronary artery disease Posted: 27 Mar 2011 05:00 PM PDT Study findings do not support a causal role for C-reactive protein in the development of coronary artery disease, say researchers.

Link between PCOS and diabetes confirmed Posted: 27 Mar 2011 05:00 PM PDT Middle-aged women with polycystic ovary syndrome have a greater long-term risk for developing Type 2 diabetes and impaired glucose tolerance than their peers without PCOS, report researchers.

Proliferative diabetic retinopathy linked to defective heart muscle perfusion Posted: 27 Mar 2011 05:00 PM PDT The frequency of defects in heart muscle perfusion at rest and after exercise increase with increasing severity of diabetic retinopathy, suggest study results.

Conflicts of interest common among CVD guideline development committees Posted: 27 Mar 2011 05:00 PM PDT An assessment of the most recently published US cardiovascular disease clinical practical guidelines reveals that more than 50% of individuals involved in the development of these guidelines disclosed a conflict of interest.

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