Medical News

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• ICS use in pregnancy “unlikely to affect fetal growth”
• Hypertension, not the metabolic syndrome, increases mortality risk in over-65s
• Hypertension, not the metabolic syndrome, increases mortality risk in over-65s
• Cannabis use linked to brain matter deficits in young schizophrenics
• PCI outcomes worsened by concurrent diabetes, hypertension
• Pioglitazone better for cardiovascular health than rosiglitazone
• MDQ ineffective for BD screening in clinical practice
• Processing inflexibility may underlie cognitive deficits in schizophrenia
• Study confirms ‘pathophysiological distinctions’ in bipolar disorder, MDD
• Folate may improve negative symptoms in some schizophrenia patients
• Lymphocyte levels may predict HF mortality risk
• Cyclothymic features in depression pose risk for bipolarity
• Illness beliefs impact QoL in early psychosis
• Impulsivity is trait feature in adolescent bipolar disorder

ICS use in pregnancy “unlikely to affect fetal growth” Posted: 20 Mar 2011 05:00 PM PDT Inhaled corticosteroid use during pregnancy does not affect glucocorticoid-regulated pathways in the placenta and fetus and is therefore unlikely to affect fetal growth, say researchers.

Hypertension, not the metabolic syndrome, increases mortality risk in over-65s Posted: 20 Mar 2011 05:00 PM PDT Results from a large French study indicate that although hypertension per se is an accurate predictor of all-cause mortality risk in individuals aged over 65 years, the metabolic syndrome is not.

Hypertension, not the metabolic syndrome, increases mortality risk in over-65s Posted: 20 Mar 2011 05:00 PM PDT Results from a large French study indicate that although hypertension per se is an accurate predictor of all-cause mortality risk in individuals aged over 65 years, the metabolic syndrome is not.

Cannabis use linked to brain matter deficits in young schizophrenics Posted: 17 Mar 2011 05:00 PM PDT Cannabis use is associated with grey and white matter deficits in patients with adolescent-onset schizophrenia, research shows.

PCI outcomes worsened by concurrent diabetes, hypertension Posted: 17 Mar 2011 05:00 PM PDT Diabetic patients who undergo percutaneous coronary intervention have a higher risk for adverse outcomes than nondiabetics who have the same procedure, study findings suggest.

Pioglitazone better for cardiovascular health than rosiglitazone Posted: 17 Mar 2011 05:00 PM PDT Results from a systematic review and meta-analysis suggest that rosiglitazone treatment is associated with significantly worse cardiovascular outcomes and higher mortality rates than pioglitazone.

MDQ ineffective for BD screening in clinical practice Posted: 17 Mar 2011 05:00 PM PDT Results from a US study do not support the use of Mood Disorders Questionnaire for bipolar disorder screening in psychiatric clinical practice because of low positive predictive values.

Processing inflexibility may underlie cognitive deficits in schizophrenia Posted: 16 Mar 2011 05:00 PM PDT Patients with schizophrenia have difficulty processing information when it requires a global strategy and instead show a preference for focusing on details, study results show.

Study confirms ‘pathophysiological distinctions’ in bipolar disorder, MDD Posted: 16 Mar 2011 05:00 PM PDT There are subtle but significant differences in gray matter architecture between patients with bipolar disorder and those with major depressive disorder who both present with psychotic features at a similar early disease stage, study results show.

Folate may improve negative symptoms in some schizophrenia patients Posted: 15 Mar 2011 05:00 PM PDT Folate supplementation appears to improve negative symptoms in schizophrenia patients, but only among those with a genetic variant of a folate-metabolizing enzyme, study results show.

Lymphocyte levels may predict HF mortality risk Posted: 15 Mar 2011 05:00 PM PDT Study findings indicate that the total lymphocyte count in heart failure patients is inversely associated with their 5-year mortality risk.

Cyclothymic features in depression pose risk for bipolarity Posted: 15 Mar 2011 05:00 PM PDT Patients with recurrent depressive disorder who score highly on measures of cyclothmic temperament frequently display risk factors for bipolarity such as early age at first depressive episode and suicidal ideation, study results show.

Illness beliefs impact QoL in early psychosis Posted: 14 Mar 2011 05:00 PM PDT The way in which individuals with psychosis perceive their illness has a significant impact on their quality of life and, by extension, overall outcome, study results show.

Impulsivity is trait feature in adolescent bipolar disorder Posted: 14 Mar 2011 05:00 PM PDT Impulsivity is a trait-based feature of adolescent bipolar disorder and thus a core feature of the illness, study results have confirmed.

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