Medical News

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• Extreme psoriasis increases mortality risk, not through CVD
• UK acute upper GI bleed rates declining
• UK acute upper GI bleed rates declining
• Longer INR follow-up interval linked to worse anticoagulation control
• Third ventricle involvement predicts ICH outcomes
• Tamoxifen compliance low in younger breast cancer survivors
• Combination therapy reduces sPLA2 activity
• Dietary advice can reduce saturated fat intake in children
• Angiography patients often have undetected diabetes and IGT
• Microvascular risk differs with gender and age at onset of Type 1 diabetes
• Use of evidence-based STEMI treatments cuts mortality risk
• Morning MIs linked to larger infarct size
• Tamoxifen compliance low in younger breast cancer survivors

Extreme psoriasis increases mortality risk, not through CVD Posted: 28 Apr 2011 05:00 PM PDT Patients with "exceptionally severe" psoriasis have an increased mortality risk compared with those with less extreme forms of the condition, but as a result of diseases other than cardiovascular disease, report researchers.

UK acute upper GI bleed rates declining Posted: 28 Apr 2011 05:00 PM PDT Findings from a 2007 UK audit show that rates of acute upper gastrointestinal bleeding have fallen by 4% since 1993.

UK acute upper GI bleed rates declining Posted: 28 Apr 2011 05:00 PM PDT Findings from a 2007 UK audit show that rates of acute upper gastrointestinal bleeding have fallen by 4% since 1993.

Longer INR follow-up interval linked to worse anticoagulation control Posted: 27 Apr 2011 05:00 PM PDT The interval between an initial out-of-range international normalized ratio value and a repeat test varies widely from clinic to clinic, even though long follow-up intervals are associated with worse anticoagulation control, US researchers report.

Third ventricle involvement predicts ICH outcomes Posted: 27 Apr 2011 05:00 PM PDT The volume of blood in the third ventricle is strong predictor of outcome in patients with intracerebral hemorrhage with severe ventricular involvement, research shows.

Tamoxifen compliance low in younger breast cancer survivors Posted: 27 Apr 2011 05:00 PM PDT Approximately half of women under 40 years of age with breast cancer discontinue tamoxifen therapy within 5 years of treatment initiation, study findings indicate.

Combination therapy reduces sPLA2 activity Posted: 27 Apr 2011 05:00 PM PDT Treatment with atorvastatin plus ezetimibe can significantly reduce the activity of secretory phospholipase A2 in patients with coronary artery disease, study results show.

Dietary advice can reduce saturated fat intake in children Posted: 27 Apr 2011 05:00 PM PDT Australian researchers say that promoting the consumption of reduced-fat dairy foods can significantly reduce saturated fat, but not energy, intake in children.

Angiography patients often have undetected diabetes and IGT Posted: 27 Apr 2011 05:00 PM PDT Previously undetected impaired glucose tolerance and Type 2 diabetes are common in patients undergoing angiography for suspected angina, suggest study results.

Microvascular risk differs with gender and age at onset of Type 1 diabetes Posted: 27 Apr 2011 05:00 PM PDT The risk for developing microvascular complications in adulthood among people with Type 1 diabetes is highly dependent on gender and age-at-onset of diabetes, say researchers.

Use of evidence-based STEMI treatments cuts mortality risk Posted: 27 Apr 2011 05:00 PM PDT The increasing use of evidence-based, guideline-recommended treatments for ST-elevation myocardial infarction has been accompanied by "large and sustained" reductions in mortality, an analysis of Swedish registry data reveals.

Morning MIs linked to larger infarct size Posted: 27 Apr 2011 05:00 PM PDT Infarct size varies according to the time of day that an ST-segment elevation myocardial infarction occurs, research from Spain suggests.

Tamoxifen compliance low in younger breast cancer survivors Posted: 27 Apr 2011 05:00 PM PDT Approximately half of women under 40 years of age with breast cancer discontinue tamoxifen therapy within 5 years of treatment initiation, study findings indicate.

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Medical News

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• Cannabis use linked to psychiatric hospitalization
• Bipolar disorder linked to increased adiposity in women
• Large registry study finds no excess cancer risk with ARB use
• High BMI linked to lower mortality after PCI, more metabolic abnormalities
• GPs promote physical activity in inactive patients
• Ketogenic diet alone can reverse diabetic nephropathy
• Diabetes may worsen post-PCI quality of life
• More data suggest calcium raises cardiac risk
• Large registry study finds no excess cancer risk with ARB use

Cannabis use linked to psychiatric hospitalization Posted: 27 Apr 2011 05:00 PM PDT There is a significant and positive dose-response relationship between cannabis use and risk for psychiatric hospitalization, study results suggest.

Bipolar disorder linked to increased adiposity in women Posted: 27 Apr 2011 05:00 PM PDT Results from an Australian study suggest a trend toward increased adiposity among women with bipolar disorder compared with mentally healthy women.

Large registry study finds no excess cancer risk with ARB use Posted: 26 Apr 2011 05:00 PM PDT An analysis of more than 100,000 patients taking angiotensin receptor blockers has found no signal that these drugs are associated with an increased risk for cancer, with the exception of a small increase in male genital cancers.

High BMI linked to lower mortality after PCI, more metabolic abnormalities Posted: 26 Apr 2011 05:00 PM PDT Study results indicate that patients with a high body mass index have low rates of all-cause mortality after percutaneous coronary intervention.

GPs promote physical activity in inactive patients Posted: 26 Apr 2011 05:00 PM PDT General practitioners can significantly increase the physical activity levels of inactive patients through "physical activity promotion programs," but the effect wears off over time, say researchers.

Ketogenic diet alone can reverse diabetic nephropathy Posted: 26 Apr 2011 05:00 PM PDT Results from a study in mice suggest that consumption of a ketogenic diet may be sufficient to reverse the symptoms of diabetic nephropathy.

Diabetes may worsen post-PCI quality of life Posted: 26 Apr 2011 05:00 PM PDT Patients with diabetes have poorer health-related quality of life at the time of percutaneous coronary intervention for acute coronary syndrome and at 6 months after the procedure compared with those without diabetes, researchers report.

More data suggest calcium raises cardiac risk Posted: 26 Apr 2011 05:00 PM PDT Latest research has shown further evidence for a link between calcium, or calcium combined with vitamin D supplementation, and cardiovascular disease.

Large registry study finds no excess cancer risk with ARB use Posted: 26 Apr 2011 05:00 PM PDT An analysis of more than 100,000 patients taking angiotensin receptor blockers has found no signal that these drugs are associated with an increased risk for cancer, with the exception of a small increase in male genital cancers.

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Medical News

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• Increased BD prevalence in Australia
• Physical HRQL linked to physical leisure activity, BMI in schizophrenia
• 1-month survival after colorectal cancer surgery varies markedly across England
• 1-month survival after colorectal cancer surgery varies markedly across England
• Clot risk higher with drospirenone than levonorgestrel oral contraceptives
• Von Willebrand Factor levels predict adverse events in AF
• Intracranial atherosclerosis underlies many post-CABG strokes
• Von Willebrand Factor levels predict adverse events in AF
• Clot risk higher with drospirenone than levonorgestrel oral contraceptives
• Patients failing to reach combined CRP, LDL goals
• Legislative changes required to tackle Canadian obesity epidemic
• Gestational diabetes prevalence varies with definition
• Low serum amylase raises metabolic syndrome, diabetes risk
• Intracranial atherosclerosis underlies many post-CABG strokes
• Stent thrombosis risk similar throughout 2 years after PCI
• Sudden cardiac death in the young more common than previously thought

Increased BD prevalence in Australia Posted: 26 Apr 2011 05:00 PM PDT There has been a significant increase in the detection and prevalence of bipolar disorder among the population of Australia since 1998, study results suggest.

Physical HRQL linked to physical leisure activity, BMI in schizophrenia Posted: 26 Apr 2011 05:00 PM PDT Reduced physical health-related quality of life in patients with schizophrenia is associated with a lack of leisure time physical activity, as well as an increased body mass index, research shows.

1-month survival after colorectal cancer surgery varies markedly across England Posted: 26 Apr 2011 05:00 PM PDT Significant variation in 30-day survival post-colorectal cancer surgery exists among National Health Service hospital trusts in England, according to findings from a UK study conducted throughout 1998–2006.

1-month survival after colorectal cancer surgery varies markedly across England Posted: 26 Apr 2011 05:00 PM PDT Significant variation in 30-day survival post-colorectal cancer surgery exists among National Health Service hospital trusts in England, according to findings from a UK study conducted throughout 1998–2006.

Clot risk higher with drospirenone than levonorgestrel oral contraceptives Posted: 25 Apr 2011 05:00 PM PDT Two studies published in the BMJ show that oral contraceptives containing the progestogen hormone drospirenone confer around twice the risk for venous thromboembolism as those containing levonorgestrel.

Von Willebrand Factor levels predict adverse events in AF Posted: 25 Apr 2011 05:00 PM PDT A high level of von Willebrand Factor is an independent risk factor for mortality and bleeding in patients with atrial fibrillation, research suggests.

Intracranial atherosclerosis underlies many post-CABG strokes Posted: 25 Apr 2011 05:00 PM PDT Atherosclerosis accounts for about half of strokes that occur soon after coronary artery bypass graft surgery, with intracranial atherosclerosis being the strongest risk factor, research suggests.

Von Willebrand Factor levels predict adverse events in AF Posted: 25 Apr 2011 05:00 PM PDT A high level of von Willebrand Factor is an independent risk factor for mortality and bleeding in patients with atrial fibrillation, research suggests.

Clot risk higher with drospirenone than levonorgestrel oral contraceptives Posted: 25 Apr 2011 05:00 PM PDT Two studies published in the BMJ show that oral contraceptives containing the progestogen hormone drospirenone confer around twice the risk for venous thromboembolism as those containing levonorgestrel.

Patients failing to reach combined CRP, LDL goals Posted: 25 Apr 2011 05:00 PM PDT Most dyslipidemic patients are not reaching the combined C-reactive protein and low-density lipoprotein cholesterol targets, suggests an analysis of the L-TAP 2 study.

Legislative changes required to tackle Canadian obesity epidemic Posted: 25 Apr 2011 05:00 PM PDT Researchers say that legislative approaches are needed to tackle the rising prevalence of overweight and obesity among Canadian children and adults.

Gestational diabetes prevalence varies with definition Posted: 25 Apr 2011 05:00 PM PDT Researchers report that the prevalence of gestational diabetes mellitus is higher when defined using International Association of Diabetes and Pregnancy Study Groups criteria than with World Health Organization criteria.

Low serum amylase raises metabolic syndrome, diabetes risk Posted: 25 Apr 2011 05:00 PM PDT Study results indicate that people with low serum amylase levels have an increased risk for cardiometabolic conditions, such as the metabolic syndrome and diabetes.

Intracranial atherosclerosis underlies many post-CABG strokes Posted: 25 Apr 2011 05:00 PM PDT Atherosclerosis accounts for about half of strokes that occur soon after coronary artery bypass graft surgery, with intracranial atherosclerosis being the strongest risk factor, research suggests.

Stent thrombosis risk similar throughout 2 years after PCI Posted: 25 Apr 2011 05:00 PM PDT Stent thrombosis within 2 years after percutaneous coronary intervention in acute myocardial infarction is relatively common, with the risk remaining unchanged from the acute through to the very late stage, concludes an analysis of the Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction trial.

Sudden cardiac death in the young more common than previously thought Posted: 25 Apr 2011 05:00 PM PDT The incidence of sudden cardiac death in young people is higher than previously thought, research from Denmark suggests.

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Health Informatics News

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Balding? Artas robot ready to harvest your hair Posted: 26 Apr 2011 05:00 AM PDT Have a seat and let the robotic hair picker get to work. Sorry, blonds and redheads. It only works on patients with straight brown or black hair.

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Medical News

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Hippocampal BDNF, trkB-TK+, and GAD67 expression reduced in BD Posted: 25 Apr 2011 05:00 PM PDT Brain-derived neurotrophic factor, tyrosine kinase receptor, and glutamic acid decarboxylase mRNA expression is reduced in the hippocampus of patients with schizophrenia, bipolar disorder, and major depression, research shows.

Increased BMI linked to brain volume reductions in BD Posted: 25 Apr 2011 05:00 PM PDT An elevated body mass index is associated with white matter volume and temporal lobe volume reductions in patients with bipolar disorder, study results suggest.

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Medical News

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• Most physicians recognize ovarian cancer symptoms, order accurate tests
• Most physicians recognize ovarian cancer symptoms, order accurate tests
• Dual contraception holds promise, but high-risk groups need intervention
• Low body weight could indicate bone loss risk during menopause
• Women worry that men would forget to take contraceptive pill
• No increased cleft risk after corticosteroid use during pregnancy
• Ambulatory BP parameters predict CV risk in diabetic patients
• Lactobacilli peptidoglycans may protect against IBD effects
• Verbal memory linked to employment in schizophrenia patients
• ‘Forgetfulness’ main reason for nonadherence in BD patients
• Early cannabis abuse linked to younger age at psychosis onset
• Hypertension link to diabetes stronger in Whites than African Americans
• Coffee consumption unlikely to influence HF event risk in women
• Gender differences in mania symptomatology
• Cultural factors influence hallucination types in schizophrenia
• CBCL-JBD phenotype does not predict Axis I disorders

Most physicians recognize ovarian cancer symptoms, order accurate tests Posted: 24 Apr 2011 05:00 PM PDT The majority of physicians would recommend diagnostic tests that are likely to lead to a correct diagnosis when presented with a patient with symptoms suggestive of ovarian cancer, show study results.

Most physicians recognize ovarian cancer symptoms, order accurate tests Posted: 24 Apr 2011 05:00 PM PDT The majority of physicians would recommend diagnostic tests that are likely to lead to a correct diagnosis when presented with a patient with symptoms suggestive of ovarian cancer, show study results.

Dual contraception holds promise, but high-risk groups need intervention Posted: 24 Apr 2011 05:00 PM PDT Dual-method contraception could prevent sexually transmitted diseases and unwanted pregnancies, but it must be consistent and maintained, report researchers.

Low body weight could indicate bone loss risk during menopause Posted: 24 Apr 2011 05:00 PM PDT Chinese study results suggest that there may be a link between low weight at menopause, and experiencing greater and faster bone loss, particularly at the spine.

Women worry that men would forget to take contraceptive pill Posted: 24 Apr 2011 05:00 PM PDT UK study results show that women would doubt men's ability to remember to take a contraceptive pill, if one was made available.

No increased cleft risk after corticosteroid use during pregnancy Posted: 24 Apr 2011 05:00 PM PDT Corticosteriod use does not significantly increase the risk for orofacial defects when used during the first trimester of pregnancy, show Danish study results.

Ambulatory BP parameters predict CV risk in diabetic patients Posted: 24 Apr 2011 05:00 PM PDT Ambulatory measures of blood pressure are able to predict the risk for cardiovascular (CV) events in people with Type 2 diabetes, study findings indicate.

Lactobacilli peptidoglycans may protect against IBD effects Posted: 24 Apr 2011 05:00 PM PDT Peptidoglycan and derived muropeptides assist probiotic functionality and may represent a useful therapeutic strategy in patients with inflammatory bowel disease, French researchers report.

Verbal memory linked to employment in schizophrenia patients Posted: 20 Apr 2011 05:00 PM PDT Results from an Italian study show that verbal memory is significantly associated with the attainment of competitive employment among patients with schizophrenia.

‘Forgetfulness’ main reason for nonadherence in BD patients Posted: 20 Apr 2011 05:00 PM PDT The main reasons for medication nonadherence in patients with bipolar disorder are forgetfulness and problems with side effects, results from a US study suggest.

Early cannabis abuse linked to younger age at psychosis onset Posted: 19 Apr 2011 05:00 PM PDT Cannabis abuse or dependency before the age of 14 years is associated with a reduced age at psychosis onset in first-episode patients, study results suggest.

Hypertension link to diabetes stronger in Whites than African Americans Posted: 19 Apr 2011 05:00 PM PDT Prehypertension and hypertension are independently associated with increased risk for Type 2 diabetes in people of White ethnicity, suggest study results.

Coffee consumption unlikely to influence HF event risk in women Posted: 19 Apr 2011 05:00 PM PDT The amount of coffee a middle-aged or older woman drinks does not affect her risk for developing heart failure, findings from a large observational study suggest.

Gender differences in mania symptomatology Posted: 19 Apr 2011 05:00 PM PDT There are significant differences between men and women with bipolar disorder regarding the symptomatology of manic episodes, results from an Indian study show.

Cultural factors influence hallucination types in schizophrenia Posted: 18 Apr 2011 05:00 PM PDT The prevalence of auditory, visual, and cenesthetic hallucinations in patients with schizophrenia is significantly influenced by cultural as well as clinical factors, study results show.

CBCL-JBD phenotype does not predict Axis I disorders Posted: 18 Apr 2011 05:00 PM PDT Researchers have found no evidence to suggest that children with attention-deficit hyperactivity disorder who have the Child Behavior Checklist-Juvenile Bipolar Disorder phenotype will go on to develop bipolar disorder or other Axis I disorders in late adolescence.

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