Medical News

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• Beetle protein makes novel thrombolytic agent
• Post-stroke fatigue tied to patient mood
• Systemic inflammation associated with atherosclerosis in psoriasis patients
• Heterogenous lung cancer resistance mechanisms reported
• Intensive statin therapy reduces risk for nonfatal CV events
• Study finds gender differences in adolescent NAFLD
• Obstructive sleep apnea may increase sight-threatening retinopathy risk
• Diabetes may raise liver-related death risk
• Mortality benefit of PCI over thrombolysis is shrinking
• HF clinical trials ‘continue to discriminate against older patients’
• Ketamine analgesia suppresses inflammatory reaction during CABG
• Postoperative NSAIDs reduce rescue medication needs
• More evidence against intra-operative transfusion for anemia patients
• Prophylactic midazolam quells ketamine reaction in adults

Beetle protein makes novel thrombolytic agent Posted: 31 Mar 2011 05:00 PM PDT Eupolytin1, a protein obtained from the mid-gut of the Chinese ground beetle, has both direct and indirect fibrinolytic properties that make it potentially useful in the treatment of thrombosis, Chinese researchers report.

Post-stroke fatigue tied to patient mood Posted: 31 Mar 2011 05:00 PM PDT Poor mental and emotional health may contribute to fatigue in stroke survivors, say UK researchers.

Systemic inflammation associated with atherosclerosis in psoriasis patients Posted: 31 Mar 2011 05:00 PM PDT Young patients with psoriasis have significantly increased arterial thickness, but no difference in vascular endothelial dysfunction compared with age- and gender-matched controls, show study results.

Heterogenous lung cancer resistance mechanisms reported Posted: 31 Mar 2011 05:00 PM PDT US researchers have identified several known and novel mechanisms by which lung cancer becomes resistant to treatment with tyrosine kinase inhibitors.

Intensive statin therapy reduces risk for nonfatal CV events Posted: 31 Mar 2011 05:00 PM PDT Intensive statin therapy can reduce the risk for nonfatal cardiovascular events compared with lower dose regimens, suggest results of a meta-analysis including more than 40,000 patients.

Study finds gender differences in adolescent NAFLD Posted: 31 Mar 2011 05:00 PM PDT The male phenotype of non-alcoholic fatty liver disease is associated with more adverse metabolic features and greater visceral adiposity than the female phenotype, despite the lower prevalence of NAFLD, say researchers.

Obstructive sleep apnea may increase sight-threatening retinopathy risk Posted: 31 Mar 2011 05:00 PM PDT Patients with diabetes who also suffer from obstructive sleep apnea are at significantly increased risk for sight threatening retinopathy relative to those without the breathing disorder, suggest study findings.

Diabetes may raise liver-related death risk Posted: 31 Mar 2011 05:00 PM PDT UK researchers report that diabetic patients are 70% more likely to die from liver disease than nondiabetics.

Mortality benefit of PCI over thrombolysis is shrinking Posted: 31 Mar 2011 05:00 PM PDT The advent of modern thrombolytic techniques has significantly attenuated the mortality benefit associated with primary percutaneous coronary intervention over thrombolysis for the treatment of ST-segment elevation myocardial infarction, Belgian researchers believe.

HF clinical trials ‘continue to discriminate against older patients’ Posted: 31 Mar 2011 05:00 PM PDT Older patients continue to be excluded from heart failure clinical trials, often without good justification, the PREDICT study has found.

Ketamine analgesia suppresses inflammatory reaction during CABG Posted: 31 Mar 2011 05:00 PM PDT Using ketamine for analgesia during coronary artery bypass graft surgery dampens the inflammatory response associated with the procedure, research shows.

Postoperative NSAIDs reduce rescue medication needs Posted: 31 Mar 2011 05:00 PM PDT Giving patients regular doses of non-steroidal anti-inflammatory drugs after outpatient surgery reduces their need for rescue analgesics and improves their perceived quality of recovery, shows a randomized trial.

More evidence against intra-operative transfusion for anemia patients Posted: 31 Mar 2011 05:00 PM PDT Further evidence against the common practice of giving intra-operative blood transfusions to patients with severe anemia is published in the journal Anesthesiology.

Prophylactic midazolam quells ketamine reaction in adults Posted: 31 Mar 2011 05:00 PM PDT Giving prophylactic midazolam to adults undergoing emergency sedation with ketamine markedly reduces their risk for emergence agitation, shows a randomized trial.

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