Medical News

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• BMI, age, parity linked to increased BP in pregnancy
• BMI, age, parity linked to increased BP in pregnancy
• Sleep spindle impairments linked to cognitive deficits in early psychosis
• Caudate choline levels reduced in medicated BD patients
• Heart rate variability linked to psychosis severity in schizophrenia
• Creativity levels increased during bipolar mania
• IQ link to schizophrenia confirmed
• Intensive glucose lowering unlikely to be effective for preventing CV events
• Cerebellar volumes reduced in bipolar I disorder patients
• Harm avoidance increases with genetic loading for schizophrenia
• BMI, fasting glucose influence Type 2 diabetes risk from hypertension
• Bipolar patients show poor decision-making in all illness phases

BMI, age, parity linked to increased BP in pregnancy Posted: 30 Jul 2011 05:00 PM PDT Obesity, older age, and lower parity are associated with increased mean blood pressure (BP) in pregnant women, UK researchers say.

BMI, age, parity linked to increased BP in pregnancy Posted: 30 Jul 2011 05:00 PM PDT Obesity, older age, and lower parity are associated with increased mean blood pressure (BP) in pregnant women, UK researchers say.

Sleep spindle impairments linked to cognitive deficits in early psychosis Posted: 28 Jul 2011 05:00 PM PDT Impairments in sleep spindles are associated with cognitive deficits in patients with early psychosis, show study findings.

Caudate choline levels reduced in medicated BD patients Posted: 28 Jul 2011 05:00 PM PDT Results from a US study suggest that medicated patients with bipolar disorder have reduced choline levels in the caudate nucleus of the basal ganglia, which is involved in mood expression and regulation.

Heart rate variability linked to psychosis severity in schizophrenia Posted: 27 Jul 2011 05:00 PM PDT Heart rate variability in patients with schizophrenia is significantly associated with the severity of their psychosis symptoms, researchers report.

Creativity levels increased during bipolar mania Posted: 27 Jul 2011 05:00 PM PDT Bipolar disorder patients who are experiencing an episode of mania, or a mixed episode, score significantly higher on measures of creativity than those who are experiencing a depressive episode, research shows.

IQ link to schizophrenia confirmed Posted: 26 Jul 2011 05:00 PM PDT Results from a systematic review and meta-analysis of published studies confirm that a low IQ is associated with an increased risk for schizophrenia.

Intensive glucose lowering unlikely to be effective for preventing CV events Posted: 26 Jul 2011 05:00 PM PDT Results from a meta-analysis published in the BMJ suggest that intensive glucose lowering in patients with Type 2 diabetes has limited cardiovascular benefits and may actually increase the risk for congestive heart failure.

Cerebellar volumes reduced in bipolar I disorder patients Posted: 26 Jul 2011 05:00 PM PDT Patients with bipolar I disorder have reduced left and right cerebellum volumes compared with mentally healthy individuals, suggest results from a Brazilian study.

Harm avoidance increases with genetic loading for schizophrenia Posted: 25 Jul 2011 05:00 PM PDT Patients with schizophrenia and their unaffected relatives score higher on measures of harm avoidance than mentally healthy individuals without a family history of schizophrenia, research shows.

BMI, fasting glucose influence Type 2 diabetes risk from hypertension Posted: 25 Jul 2011 05:00 PM PDT Clinicians should focus on treating metabolic risk factors for Type 2 diabetes as well as blood pressure in patients with hypertension, report Korean researchers.

Bipolar patients show poor decision-making in all illness phases Posted: 25 Jul 2011 05:00 PM PDT Researchers have found that patients with bipolar disorder show equally poor decision-making ability across all three phases of the illness compared with mentally healthy individuals.

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Medical News

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New performance measures issued for CAD, hypertension care Posted: 26 Jun 2011 05:00 PM PDT Updated performance measures for coronary artery disease and hypertension care have been issued by the Physician Consortium for Performance Improvement committee.

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• N-terminal of ADAMTS13 essential for arterial thrombosis inhibition
• Young people should increase dairy intake to improve CVD risk factors
• Adiposity explains associations between sedentary behavior and CV risk factors
• Variants in <i>PPARγ</i> may increase risk for gestational diabetes
• Survival after first MI remains poor among diabetics
• Survival rates improved in centers combining high-quality AMI, HF care
• Bleeding risk terminates apixaban trial

N-terminal of ADAMTS13 essential for arterial thrombosis inhibition Posted: 28 Jul 2011 05:00 PM PDT The amino terminus of the metalloprotease ADAMTS13 has a crucial role in the modulation of arterial thromboses, study findings indicate.

Young people should increase dairy intake to improve CVD risk factors Posted: 28 Jul 2011 05:00 PM PDT Researchers say that dairy fatty acid intake early in life should be increased, after finding that dairy-specific saturated fats were beneficially associated with a reduction in cardiovascular disease risk factors among adolescents, especially those who were overweight.

Adiposity explains associations between sedentary behavior and CV risk factors Posted: 28 Jul 2011 05:00 PM PDT Markers of adiposity largely explain the association between sedentary behavior and cardiometabolic risk factors, study findings suggest.

Variants in <i>PPARγ</i> may increase risk for gestational diabetes Posted: 28 Jul 2011 05:00 PM PDT Two variants in the peroxisome proliferator-activated receptor-γ gene are associated with increased risk for gestational diabetes mellitus, report French researchers.

Survival after first MI remains poor among diabetics Posted: 28 Jul 2011 05:00 PM PDT Long-term survival after a first myocardial infarction is significantly lower among patients with diabetes than those without the condition, researchers report.

Survival rates improved in centers combining high-quality AMI, HF care Posted: 28 Jul 2011 05:00 PM PDT Hospitals that provide superior care for both acute myocardial infarction and heart failure patients have better survival rates than those that provide superior care for only one of these conditions, say researchers.

Bleeding risk terminates apixaban trial Posted: 28 Jul 2011 05:00 PM PDT Addition of apixaban to antiplatelet therapy for acute coronary syndrome patients increases major bleeding without significantly reducing recurrent ischemic events, results from the prematurely terminated APPRAISE-2 trial show.

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• Vascular risk factors spark rise in pregnancy-related stroke
• Simple test confirms chronic thromboembolic pulmonary hypertension
• Sleep spindle impairments linked to cognitive deficits in early psychosis
• Caudate choline levels reduced in medicated BD patients
• Vascular risk factors spark rise in pregnancy-related stroke
• Triple therapy best for H. pylori eradication in Latin America
• Thrombin generation increased in hormone therapy users
• Genetics play minimal role in stroke risk
• Poor physical fitness increases CVD risk among metabolic syndrome patients
• NICE issues draft guidance on genetic testing for FH
• OGTT more reliable than HbA1c for detecting ‘silent’ diabetes
• Menopause does not increase diabetes risk
• Good pre-PCI adherence to daily meds indicates continued clopidogrel use after
• Polymer-free stents ‘noninferior’ to polymer-based stents in CAD
• Poor physical fitness increases CVD risk among metabolic syndrome patients
• Genetics play minimal role in stroke risk
• Central BP determines hypertension risk from ISH at young age

Vascular risk factors spark rise in pregnancy-related stroke Posted: 28 Jul 2011 05:00 PM PDT US researchers have identified a large increase in the proportion of pregnant women who are hospitalized with stroke.

Simple test confirms chronic thromboembolic pulmonary hypertension Posted: 28 Jul 2011 05:00 PM PDT Researchers have constructed an algorithm that simply and accurately rules out chronic thromboembolic pulmonary hypertension, without the need for invasive testing, in acute pulmonary embolism patients.

Sleep spindle impairments linked to cognitive deficits in early psychosis Posted: 28 Jul 2011 05:00 PM PDT Impairments in sleep spindles are associated with cognitive deficits in patients with early psychosis, show study findings.

Caudate choline levels reduced in medicated BD patients Posted: 28 Jul 2011 05:00 PM PDT Results from a US study suggest that medicated patients with bipolar disorder have reduced choline levels in the caudate nucleus of the basal ganglia, which is involved in mood expression and regulation.

Vascular risk factors spark rise in pregnancy-related stroke Posted: 28 Jul 2011 05:00 PM PDT US researchers have identified a large increase in the proportion of pregnant women who are hospitalized with stroke.

Triple therapy best for H. pylori eradication in Latin America Posted: 28 Jul 2011 05:00 PM PDT A standard 14-day, three-drug eradication regimen for Helicobacter pylori is superior to more intensive four-drug regimens, a large clinical trial conducted across Latin America has found.

Thrombin generation increased in hormone therapy users Posted: 27 Jul 2011 05:00 PM PDT Women using hormone therapy have increased thrombin generation, which varies according to both the route of estrogen administration and the type of progestogen used, French researchers report.

Genetics play minimal role in stroke risk Posted: 27 Jul 2011 05:00 PM PDT Myocardial infarction, but not stroke, clusters in families, show data from a population-based study.

Poor physical fitness increases CVD risk among metabolic syndrome patients Posted: 27 Jul 2011 05:00 PM PDT Physical fitness levels should be included in cardiovascular disease risk assessment, especially among individuals with the metabolic syndrome, according to UK researchers.

NICE issues draft guidance on genetic testing for FH Posted: 27 Jul 2011 05:00 PM PDT The UK's National Institute for Health and Clinical Excellence has issued draft guidance that does not support the use of two genetic tests for the diagnosis of familial hypercholesterolemia.

OGTT more reliable than HbA1c for detecting ‘silent’ diabetes Posted: 27 Jul 2011 05:00 PM PDT Clinicians should routinely perform an oral glucose tolerance test on coronary artery disease patients with no previous history of diabetes who are admitted for coronary angiography, researchers report.

Menopause does not increase diabetes risk Posted: 27 Jul 2011 05:00 PM PDT Study findings suggest that a woman's risk for Type 2 diabetes is not increased while going through natural or non-natural menopause.

Good pre-PCI adherence to daily meds indicates continued clopidogrel use after Posted: 27 Jul 2011 05:00 PM PDT Study findings suggest that measuring patients' adherence to daily medications before they undergo percutaneous coronary intervention could help cardiologists judge how likely they are to keep taking clopidogrel afterwards – and thereby choose the best intervention approach.

Polymer-free stents ‘noninferior’ to polymer-based stents in CAD Posted: 27 Jul 2011 05:00 PM PDT Researchers report that polymer-free drug-eluting stents are noninferior in terms of safety and efficacy to polymer-based equivalents in coronary artery disease patients.

Poor physical fitness increases CVD risk among metabolic syndrome patients Posted: 27 Jul 2011 05:00 PM PDT Physical fitness levels should be included in cardiovascular disease risk assessment, especially among individuals with the metabolic syndrome, according to UK researchers.

Genetics play minimal role in stroke risk Posted: 27 Jul 2011 05:00 PM PDT Myocardial infarction, but not stroke, clusters in families, show data from a population-based study.

Central BP determines hypertension risk from ISH at young age Posted: 26 Jun 2011 05:00 PM PDT Research suggests that young-to-middle aged people with isolated systolic hypertension are at increased risk for developing hypertension needing drug therapy, but only if they have high central blood pressure.

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Medical News

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• Heart rate variability linked to psychosis severity in schizophrenia
• Creativity levels increased during bipolar mania
• Elevated liver, abdominal fat in obese indicate high cardiac disease risk
• BMI influences the association between red wine consumption and triglycerides
• Intensive glucose lowering unlikely to be effective for preventing CV events
• Atorvastatin favorably alters adipokine levels in Type 2 diabetics
• Intensive glucose lowering unlikely to be effective for preventing CV events
• Combined model improves sudden cardiac death risk prediction
• Defibrillation, CPR, gender predict survival after out of hospital cardiac arrest

Heart rate variability linked to psychosis severity in schizophrenia Posted: 27 Jul 2011 05:00 PM PDT Heart rate variability in patients with schizophrenia is significantly associated with the severity of their psychosis symptoms, researchers report.

Creativity levels increased during bipolar mania Posted: 27 Jul 2011 05:00 PM PDT Bipolar disorder patients who are experiencing an episode of mania, or a mixed episode, score significantly higher on measures of creativity than those who are experiencing a depressive episode, research shows.

Elevated liver, abdominal fat in obese indicate high cardiac disease risk Posted: 26 Jul 2011 05:00 PM PDT Researchers report that obese individuals with raised levels of liver and subcutaneous abdominal fat may be at increased risk for cardiometabolic disease.

BMI influences the association between red wine consumption and triglycerides Posted: 26 Jul 2011 05:00 PM PDT Short-term red wine consumption increases plasma triglyceride levels, say researchers, who add that this is particularly the case in individuals with a higher body mass index.

Intensive glucose lowering unlikely to be effective for preventing CV events Posted: 26 Jul 2011 05:00 PM PDT Results from a meta-analysis published in the BMJ suggest that intensive glucose lowering in patients with Type 2 diabetes has limited cardiovascular benefits and may actually increase the risk for congestive heart failure.

Atorvastatin favorably alters adipokine levels in Type 2 diabetics Posted: 26 Jul 2011 05:00 PM PDT Atorvastatin alters levels of novel adipokines, suggesting that a link between adiposity, inflammation, and cardiovascular function may underlie the beneficial effects of statins in diabetic patients, say researchers.

Intensive glucose lowering unlikely to be effective for preventing CV events Posted: 26 Jul 2011 05:00 PM PDT Results from a meta-analysis published in the BMJ suggest that intensive glucose lowering in patients with Type 2 diabetes has limited cardiovascular benefits and may actually increase the risk for congestive heart failure.

Combined model improves sudden cardiac death risk prediction Posted: 26 Jul 2011 05:00 PM PDT A risk model combining left ventricular ejection fraction with clinical risk factors is a better predictor of sudden cardiac death in women with coronary artery disease than LVEF alone, researchers suggest.

Defibrillation, CPR, gender predict survival after out of hospital cardiac arrest Posted: 26 Jul 2011 05:00 PM PDT A short delay to defibrillation, bystander cardiopulmonary resuscitation, and female gender are strong predictors of survival after out-of-hospital cardiac arrest, a Swedish team reports.

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