Medical News

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• High clopidogrel loading dose reduces infarct size
• Kidney donors not at increased cardiovascular risk
• FPG predicts glycemic outcome with insulin glargine therapy
• Pericardial fat predicts high-risk coronary lesions
• Computer tool aids women in contraceptive choice
• Ingenol mebutate gel effective for treatment of actinic keratosis
• Thrombolysis ‘not supported’ in PE
• CLOSURE I shows no benefits of PFO closure in cryptogenic stroke
• CLOSURE I shows no benefits of PFO closure in cryptogenic stroke

High clopidogrel loading dose reduces infarct size Posted: 15 Mar 2012 05:00 PM PDT A 600 mg loading dose of clopidogrel before percutaneous coronary intervention reduces myocardial infarct size and improves myocardial salvage compared with a 300 mg loading dose, say researchers.

Kidney donors not at increased cardiovascular risk Posted: 15 Mar 2012 05:00 PM PDT Kidney donors do not have an increased risk for adverse cardiovascular outcomes in the first decade after donation, a British Medical Journal study shows.

FPG predicts glycemic outcome with insulin glargine therapy Posted: 15 Mar 2012 05:00 PM PDT Fasting plasma glucose measured early in the course of treatment can identify patients who are unlikely to achieve glycated hemoglobin goals with insulin glargine therapy and who may therefore benefit from a re-evaluation of their treatment options, report researchers.

Pericardial fat predicts high-risk coronary lesions Posted: 15 Mar 2012 05:00 PM PDT Patients with high-risk coronary lesions have significantly higher amounts of pericardial fat compared with those without high-risk lesions and those without any coronary artery disease, report US researchers.

Computer tool aids women in contraceptive choice Posted: 15 Mar 2012 05:00 PM PDT Women who use a computer-based contraceptive assessment module choose more effective contraception methods than those who do not, a study has found.

Ingenol mebutate gel effective for treatment of actinic keratosis Posted: 15 Mar 2012 05:00 PM PDT Results show that topically applied ingenol mebutate gel is an effective therapy for actinic keratosis, reducing lesion treatment time from several months to a few days.

Thrombolysis ‘not supported’ in PE Posted: 15 Mar 2012 05:00 PM PDT Thrombolysis does not significantly decrease the risk for death among hypotensive patients with pulmonary embolism and may increase mortality in those with normal blood pressure, shows an analysis of RIETE registry data.

CLOSURE I shows no benefits of PFO closure in cryptogenic stroke Posted: 14 Mar 2012 05:00 PM PDT Closing a patent foramen ovale in patients with cryptogenic stroke does not reduce the rate of recurrent stroke or transient ischemic attack, the CLOSURE I team reports in the New England Journal of Medicine.

CLOSURE I shows no benefits of PFO closure in cryptogenic stroke Posted: 14 Mar 2012 05:00 PM PDT Closing a patent foramen ovale in patients with cryptogenic stroke does not reduce the rate of recurrent stroke or transient ischemic attack, the CLOSURE I team reports in the New England Journal of Medicine.

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