Tuesday, April 23, 2013

Medical News

Medical News


Bipolar disorder questionnaires limited for patients with SUD

Posted: 23 Apr 2013 05:00 PM PDT

Researchers advise caution when using the Mood Disorder Questionnaire and the Hypomania Checklist-32 to diagnose bipolar disorder in patients treated for substance use disorders.

Bipolar disorder questionnaires limited for patients with SUD

Posted: 23 Apr 2013 05:00 PM PDT

Researchers advise caution when using the Mood Disorder Questionnaire and the Hypomania Checklist-32 to diagnose bipolar disorder in patients treated for substance use disorders.

Research supports polygenic phenotype in schizophrenia

Posted: 23 Apr 2013 05:00 PM PDT

Cumulative genetic risk for schizophrenia has been linked to impaired prefrontal brain activity, in findings that support an additive genetic risk model for a polygenic phenotype.

Research supports polygenic phenotype in schizophrenia

Posted: 23 Apr 2013 05:00 PM PDT

Cumulative genetic risk for schizophrenia has been linked to impaired prefrontal brain activity, in findings that support an additive genetic risk model for a polygenic phenotype.

Pain common in depressed bipolar patients

Posted: 22 Apr 2013 05:00 PM PDT

Results from a Spanish study suggest that chronic pain is common among patients with bipolar disorder who are experiencing an episode of depression.

Tamoxifen breast changes predict survival

Posted: 22 Apr 2013 05:00 PM PDT

Women with breast cancer who experience a tamoxifen-related decrease in mammographic density have significantly better survival than patients whose breast density is unaffected by the agent, suggest study findings.

HAART to heart for children with HIV

Posted: 22 Apr 2013 05:00 PM PDT

Long-term highly active antiretroviral therapy appears to protect children with HIV from associated cardiac problems, suggest study findings.

HAART to heart for children with HIV

Posted: 22 Apr 2013 05:00 PM PDT

Long-term highly active antiretroviral therapy appears to protect children with HIV from associated cardiac problems, suggest study findings.

Tamoxifen breast changes predict survival

Posted: 22 Apr 2013 05:00 PM PDT

Women with breast cancer who experience a tamoxifen-related decrease in mammographic density have significantly better survival than patients whose breast density is unaffected by the agent, suggest study findings.

Radiotherapy improves QoL among elderly with bone metastases

Posted: 22 Apr 2013 05:00 PM PDT

Radiotherapy can significantly improve the quality of life of elderly individuals with cancer that has metastasized to the bone, show study results presented at the 2nd European Society for Radiotherapy and Oncology Forum in Geneva, Switzerland.

Tamoxifen breast changes predict survival

Posted: 22 Apr 2013 05:00 PM PDT

Women with breast cancer who experience a tamoxifen-related decrease in mammographic density have significantly better survival than patients whose breast density is unaffected by the agent, suggest study findings.

Paranoia impacts facial emotion recognition in schizophrenia

Posted: 22 Apr 2013 05:00 PM PDT

Researchers report that patients with schizophrenia differ in their ability to recognize facial emotions depending on whether they have the paranoid or non-paranoid subtype.

Pain common in depressed bipolar patients

Posted: 22 Apr 2013 05:00 PM PDT

Results from a Spanish study suggest that chronic pain is common among patients with bipolar disorder who are experiencing an episode of depression.

Nutritional supplementation boosts COPD rehabilitation

Posted: 22 Apr 2013 05:00 PM PDT

Combining high-carbohydrate nutritional supplementation with pulmonary rehabilitation may help reverse weight loss and muscle wasting in patients with chronic obstructive pulmonary disease, research suggests.

Single allergen sensitization tests may miss cases in children

Posted: 22 Apr 2013 05:00 PM PDT

There is significant discordance between the results of allergen-specific skin prick tests and allergen-specific serum immunoglobulin E levels for identifying aeroallergen sensitization in children under the age of 4 years, a study finds.

Paranoia impacts facial emotion recognition in schizophrenia

Posted: 22 Apr 2013 05:00 PM PDT

Researchers report that patients with schizophrenia differ in their ability to recognize facial emotions depending on whether they have the paranoid or non-paranoid subtype.

Shock waves improve intracoronary cell therapy in heart failure

Posted: 21 Apr 2013 05:00 PM PDT

Pretreatment with targeted shock wave therapy improves recovery of left ventricular ejection fraction in patients with heart failure receiving intracoronary administration of bone-marrow-derived mononuclear cells, a German study shows.

Hypertensive pregnancy disorders linked to diabetes

Posted: 21 Apr 2013 05:00 PM PDT

Women who are diagnosed with pre-eclampsia or hypertension during pregnancy are at increased risk for developing diabetes, particularly if they experience these conditions alongside gestational diabetes, research shows.

Hypertensive pregnancy disorders linked to diabetes

Posted: 21 Apr 2013 05:00 PM PDT

Women who are diagnosed with pre-eclampsia or hypertension during pregnancy are at increased risk for developing diabetes, particularly if they experience these conditions alongside gestational diabetes, research shows.

Orlistat liver injury link questioned

Posted: 21 Apr 2013 05:00 PM PDT

Researchers have found that users of the obesity drug, orlistat, have an increased risk for acute liver injury compared with non-users in the time period prior to taking the drug.

Kidney disease screening needs rethink in hypertension

Posted: 21 Apr 2013 05:00 PM PDT

The standard approach to detecting chronic kidney disease fails to spot the condition in about a quarter of patients with hypertension, a study suggests.

Experience key for radiologic diagnosis of pediatric respiratory infection

Posted: 21 Apr 2013 05:00 PM PDT

Research suggests that there is little agreement between physicians when reading chest X-rays for diagnosing pediatric respiratory diseases such as pneumonia.

Orlistat liver injury link questioned

Posted: 21 Apr 2013 05:00 PM PDT

Researchers have found that users of the obesity drug, orlistat, have an increased risk for acute liver injury compared with non-users in the time period prior to taking the drug.

Hypertensive pregnancy disorders linked to diabetes

Posted: 21 Apr 2013 05:00 PM PDT

Women who are diagnosed with pre-eclampsia or hypertension during pregnancy are at increased risk for developing diabetes, particularly if they experience these conditions alongside gestational diabetes, research shows.

Exercise-related breast pain affects third of female runners

Posted: 21 Apr 2013 05:00 PM PDT

Research suggests that around a third of women who run regularly experience breast pain or mastalgia as a result.

Tea and coffee may protect against oral cancer

Posted: 21 Apr 2013 05:00 PM PDT

Consumption of tea and coffee is inversely correlated with the risk for cancer of the oral cavity, a large population-based study suggests.

Multiphasic multidetector CT aids renal cell carcinoma differentiation

Posted: 21 Apr 2013 05:00 PM PDT

Multiphasic multidetector computed tomography may help clinicians discriminate clear cell renal cell carcinoma from oncocytoma, papillary RCC, and chromophobe RCC, study findings suggest.

Sjögren’s syndrome found in one-fifth of lupus patients

Posted: 21 Apr 2013 05:00 PM PDT

Researchers have identified key characteristics that predict the development of Sjögren's syndrome in patients with systemic lupus erythematosus, finding that up to a fifth of patients are affected.

Bolus iron fights hemodialysis patient anemia

Posted: 21 Apr 2013 05:00 PM PDT

Research suggests that bolus intravenous iron could be the optimal treatment for anemia in patients undergoing hemodialysis, subject to further investigation.

Surgery for renal cancer not always needed in elderly individuals

Posted: 21 Apr 2013 05:00 PM PDT

Physicians may want to consider nonsurgical management of patients with localized renal cell carcinoma if they are aged 75 years or more, say researchers.

Study refutes poor antidepressant response in bipolar disorder

Posted: 18 Apr 2013 05:00 PM PDT

Research findings oppose the view that patients with bipolar disorder have a worse response to antidepressants than patients with unipolar depression.

Further effort to reduce CV risk factors in diabetes needed in Korea

Posted: 18 Apr 2013 05:00 PM PDT

Significant progress has been made since 2005 in reducing cardiovascular risk factors among Korean adults diagnosed with diabetes, report researchers.

Further effort to reduce CV risk factors in diabetes needed in Korea

Posted: 18 Apr 2013 05:00 PM PDT

Significant progress has been made since 2005 in reducing cardiovascular risk factors among Korean adults diagnosed with diabetes, report researchers.

mTOT modulator shows proof-of-concept in diabetes

Posted: 18 Apr 2013 05:00 PM PDT

A proof-of-concept study indicates that treatment with a mitochondrial target of thiazolidinediones modulator effectively lowers glucose levels in patients with Type 2 diabetes.

Climate change linked to US Lyme disease spread

Posted: 18 Apr 2013 05:00 PM PDT

Researchers have found that over the past 20 years, the incidence of Lyme disease has increased in the northern-most states of the USA, while declining in more southerly states.

HPV infection plays major role in oropharyngeal cancer

Posted: 18 Apr 2013 05:00 PM PDT

Infection with human papillomavirus type 16 has an important role in the etiology of oropharyngeal cancers, results from a large case–control study indicate.

HPV infection plays major role in oropharyngeal cancer

Posted: 18 Apr 2013 05:00 PM PDT

Infection with human papillomavirus type 16 has an important role in the etiology of oropharyngeal cancers, results from a large case–control study indicate.

Birth weight linked to neurocognition in schizophrenia

Posted: 18 Apr 2013 05:00 PM PDT

Lower birth weight is associated with greater impairments in specific areas of neurocognition among patients with schizophrenia spectrum disorders, report US researchers.

Study refutes poor antidepressant response in bipolar disorder

Posted: 18 Apr 2013 05:00 PM PDT

Research findings oppose the view that patients with bipolar disorder have a worse response to antidepressants than patients with unipolar depression.

Burden of COPD-related ED care ‘significant’

Posted: 18 Apr 2013 05:00 PM PDT

Results from a US study reveal the high population-based burden of chronic obstructive pulmonary disease-related care in emergency departments.

Asthma linked to less severe outcomes after H1N1 infection

Posted: 18 Apr 2013 05:00 PM PDT

Patients with asthma who were admitted to hospital with influenza A H1N1 were significantly less likely to experience a severe outcome than those without asthma, UK study results show.

Maternal asthma-controller use not linked to perinatal outcomes

Posted: 18 Apr 2013 05:00 PM PDT

The maternal use of asthma-controller therapy during pregnancy is not significantly associated with adverse perinatal outcomes, study findings show.

Birth weight linked to neurocognition in schizophrenia

Posted: 18 Apr 2013 05:00 PM PDT

Lower birth weight is associated with greater impairments in specific areas of neurocognition among patients with schizophrenia spectrum disorders, report US researchers.

‘Adaptive coping’ key to successful home dialysis

Posted: 18 Apr 2013 05:00 PM PDT

The odds for patients with end-stage renal disease successfully sustaining their home hemodialysis therapy seems to depend on the coping mechanisms they employ, report Australian researchers.

Simple assessment predicts need for reintubation

Posted: 17 Apr 2013 05:00 PM PDT

A simple scoring system allows anesthesiologists to reliably predict severe postoperative respiratory complications, researchers report in Anesthesiology.

Cognitive deficits in elderly bipolar patients may herald dementia

Posted: 17 Apr 2013 05:00 PM PDT

Elderly patients with bipolar disorder have persistent cognitive dysfunction, prospective study findings suggest.

PPIs alone not linked to gastrointestinal infection

Posted: 17 Apr 2013 05:00 PM PDT

Researchers have shown that a previously suggested link between the use of proton pump inhibitors and gastrointestinal infections with Campylobacter and Salmonella is due to the characteristics of the patients and not the drugs themselves.

Infant colic implicated in childhood migraines

Posted: 17 Apr 2013 05:00 PM PDT

Infants who suffer from colic are more likely to experience migraine, but not tension headaches, in later childhood and adolescence than those who do not, show study results published in JAMA.

PPIs alone not linked to gastrointestinal infection

Posted: 17 Apr 2013 05:00 PM PDT

Researchers have shown that a previously suggested link between the use of proton pump inhibitors and gastrointestinal infections with Campylobacter and Salmonella is due to the characteristics of the patients and not the drugs themselves.

Triple antiseptic strategy wipes out preoperative bacteria

Posted: 17 Apr 2013 05:00 PM PDT

Meta-analysis results point to a triple-chemical skin cleansing strategy to help reduce the risk for surgical site infection after foot and ankle operations.

CVD risk increased in Chinese patients with schizophrenia

Posted: 17 Apr 2013 05:00 PM PDT

Chinese patients with schizophrenia have an elevated mean 10-year risk for cardiovascular disease, researchers have found.

NDEL1 enzyme activity reduced in schizophrenia

Posted: 17 Apr 2013 05:00 PM PDT

Results from a Brazilian study show that nuclear distribution protein nudE-like 1 enzyme activity is reduced in patients with schizophrenia compared with mentally healthy individuals.

Still no support for primary care intimate partner violence screening

Posted: 17 Apr 2013 05:00 PM PDT

An Australian study has found no evidence of improvement in primary outcomes for women who are screened and counselled for intimate partner violence in primary care.

Cognitive deficits in elderly bipolar patients may herald dementia

Posted: 17 Apr 2013 05:00 PM PDT

Elderly patients with bipolar disorder have persistent cognitive dysfunction, prospective study findings suggest.

Simple assessment predicts need for reintubation

Posted: 17 Apr 2013 05:00 PM PDT

A simple scoring system allows anesthesiologists to reliably predict severe postoperative respiratory complications, researchers report in Anesthesiology.

Moderate- outweighs light-pressure massage for rheumatoid arthritis pain

Posted: 17 Apr 2013 05:00 PM PDT

Moderate-pressure massage benefits people with rheumatoid arthritis in their upper limbs by reducing pain and improving grip strength and range of motion, say researchers.

CVD risk increased in Chinese patients with schizophrenia

Posted: 17 Apr 2013 05:00 PM PDT

Chinese patients with schizophrenia have an elevated mean 10-year risk for cardiovascular disease, researchers have found.

Facial fear recognition responses identified in adolescent bipolar disorder

Posted: 16 Apr 2013 05:00 PM PDT

Patients with adolescent bipolar disorder show increased neural activity and a prolonged response when presented with fearful faces compared with neutral faces, suggest study findings.

Heart rate more than fitness marker

Posted: 16 Apr 2013 05:00 PM PDT

Long-term follow up of men in the Copenhagen Male Study has separated out the effects of resting heart rate and physical fitness on mortality risk

‘Breathprint’ offers efficient diagnosis of heart failure

Posted: 16 Apr 2013 05:00 PM PDT

Analysis of a single exhaled breath of air or "breathprint" can be used to quickly diagnose patients with heart failure, shows research.

Invasive cardiac monitoring revealing in cryptogenic stroke

Posted: 16 Apr 2013 05:00 PM PDT

Long-term observation with an implantable cardiac monitoring device detects paroxysmal atrial fibrillation in about a quarter of patients with cryptogenic ischemic stroke, research shows.

Surgery should not be default for rectoceles

Posted: 16 Apr 2013 05:00 PM PDT

Researchers have found no difference in anorectal physiology or severity of obstructed defecation syndrome between patients with and without rectoceles.

‘Breathprint’ offers efficient diagnosis of heart failure

Posted: 16 Apr 2013 05:00 PM PDT

Analysis of a single exhaled breath of air or "breathprint" can be used to quickly diagnose patients with heart failure, shows research.

Turning up the heat on dengue

Posted: 16 Apr 2013 05:00 PM PDT

Research published in the Proceedings of the National Academy of Sciences shows that dengue virus particles or virions change their shape at human body temperature.

Chronic nerve damage found in post-herpetic neuralgia

Posted: 16 Apr 2013 05:00 PM PDT

Pain and discomfort in people with post-herpetic neuralgia typically resolve within months of infection yet sensory function and innervation can remain abnormal for many years, an observational study indicates.

Surgery should not be default for rectoceles

Posted: 16 Apr 2013 05:00 PM PDT

Researchers have found no difference in anorectal physiology or severity of obstructed defecation syndrome between patients with and without rectoceles.

Lower PSA linked to greater survival with sipuleucel-T in prostate cancer

Posted: 16 Apr 2013 05:00 PM PDT

Sipuleucel-T treatment may be of the most benefit to patients with metastatic castration-resistant prostate cancer who have low prostate specific antigen levels, say US researchers.

Smoking significant contributor to asbestos-related lung cancer

Posted: 16 Apr 2013 05:00 PM PDT

Quitting smoking significantly reduces a person's chance of getting lung cancer after being exposed to asbestos, suggest study findings.

Cancer patients and physicians support assisted dying program

Posted: 16 Apr 2013 05:00 PM PDT

A Death with Dignity program, in which physicians can assist cancer patients with a prognosis of less than 6 months to end their lives, has been well-accepted by patients and their families, and received growing support from the physicians involved.

Smoking significant contributor to asbestos-related lung cancer

Posted: 16 Apr 2013 05:00 PM PDT

Quitting smoking significantly reduces a person's chance of getting lung cancer after being exposed to asbestos, suggest study findings.

Invasive cardiac monitoring revealing in cryptogenic stroke

Posted: 16 Apr 2013 05:00 PM PDT

Long-term observation with an implantable cardiac monitoring device detects paroxysmal atrial fibrillation in about a quarter of patients with cryptogenic ischemic stroke, research shows.

Schizophrenia may shorten lifespan

Posted: 16 Apr 2013 05:00 PM PDT

Study results suggest that individuals with schizophrenia die at a younger age than the general population.

Lower PSA linked to greater survival with sipuleucel-T in prostate cancer

Posted: 16 Apr 2013 05:00 PM PDT

Sipuleucel-T treatment may be of the most benefit to patients with metastatic castration-resistant prostate cancer who have low prostate specific antigen levels, say US researchers.

Global vascular risk factors for cognitive decline modifiable

Posted: 15 Apr 2013 05:00 PM PDT

Vascular risk factors that are potentially modifiable are associated with cognitive decline in aging populations, show research findings.

Phototherapy plus reflecting curtains effective for neonatal jaundice

Posted: 15 Apr 2013 05:00 PM PDT

Neonatal hyperbilirubinemia requiring intensive phototherapy can be treated equally well with single phototherapy using reflecting curtains as with double phototherapy, the results of a study indicate.

Dose-intense chemotherapy not superior for B-cell lymphoma

Posted: 15 Apr 2013 05:00 PM PDT

Compressing R-CHOP treatment cycles does not improve the outcome of elderly patients with diffuse large B-cell lymphoma, suggests research published in The Lancet Oncology.

Depressive symptoms worsen acute COPD exacerbation outcomes

Posted: 15 Apr 2013 05:00 PM PDT

Patients with acute exacerbations of chronic obstructive pulmonary disease have an increased risk for a poor outcome if they have depressive symptoms, say scientists.

CD8 cell subset count linked to airway obstruction in asthma

Posted: 15 Apr 2013 05:00 PM PDT

The frequency of a subset of CD8 T lymphocytes expressing the high-affinity receptor for LTB4 and producing interleukin-13 is significantly greater in the airways of patients with asthma than healthy people, a study finds.

Obesity linked to reduced cognition in schizophrenia

Posted: 15 Apr 2013 05:00 PM PDT

Patients with schizophrenia who are obese have poorer cognitive function than their normal-weight counterparts, results from a Chinese study show.

Obesity impacts quality of life in Japanese schizophrenia patients

Posted: 15 Apr 2013 05:00 PM PDT

Obesity has a significant and negative impact on the quality of life of Japanese patients with schizophrenia, study findings show.

Heart surgery risk in radiation-treated cancer survivors

Posted: 14 Apr 2013 05:00 PM PDT

Cancer survivors who are treated with chest radiation are nearly twice as likely to die in the years following major heart surgery as patients undergoing similar surgery who are never treated with radiation, a study shows.

HCV infection alone not linked to diabetes risk

Posted: 14 Apr 2013 05:00 PM PDT

Individuals with hepatitis C virus infection are at increased risk for developing Type 2 diabetes only if they have elevated alanine aminotransferase levels, show study findings published in the American Journal of Gastroenterology.

HCV infection alone not linked to diabetes risk

Posted: 14 Apr 2013 05:00 PM PDT

Individuals with hepatitis C virus infection are at increased risk for developing Type 2 diabetes only if they have elevated alanine aminotransferase levels, show study findings published in the American Journal of Gastroenterology.

Push to reduce global salt intake

Posted: 14 Apr 2013 05:00 PM PDT

Countries should aim for even lower adult salt consumption than the current World Health Organization targets, say researchers.

Tonsillectomy benefits adults with recurrent pharyngitis

Posted: 14 Apr 2013 05:00 PM PDT

Adults who experience recurrent pharyngitis may benefit from having their tonsils removed, report researchers.

HCV infection alone not linked to diabetes risk

Posted: 14 Apr 2013 05:00 PM PDT

Individuals with hepatitis C virus infection are at increased risk for developing Type 2 diabetes only if they have elevated alanine aminotransferase levels, show study findings published in the American Journal of Gastroenterology.

Complication rates following rotational forceps delivery ‘low’

Posted: 14 Apr 2013 05:00 PM PDT

The short-term rates of neonatal and maternal complications following successful Kielland's rotational forceps delivery are low and comparable with other forms of delivery, and lower than those seen with cesarean delivery, say UK investigators.

Heart surgery risk in radiation-treated cancer survivors

Posted: 14 Apr 2013 05:00 PM PDT

Cancer survivors who are treated with chest radiation are nearly twice as likely to die in the years following major heart surgery as patients undergoing similar surgery who are never treated with radiation, a study shows.

Bisphosphonate therapy may aid osteoarthritis patients

Posted: 14 Apr 2013 05:00 PM PDT

Research adds weight to reports that patients with knee osteoarthritis may experience benefits in pain or progression relief from bisphosphonate treatment.

Stroke score predicts long-term prognosis

Posted: 14 Apr 2013 05:00 PM PDT

The ASTRAL score reliably predicts 5-year functional outcome and mortality in patients with acute ischemic stroke, research shows.

Prostate calcification linked to LUTS

Posted: 14 Apr 2013 05:00 PM PDT

Moderate-to-marked prostatic calcification is an independent risk factor for moderate-to-severe lower urinary tract symptoms, report researchers.

Boosting testosterone does not boost wellbeing, mood in ED patients

Posted: 14 Apr 2013 05:00 PM PDT

Adding testosterone to sildenafil treatment in men who have erectile dysfunction and low testosterone levels provides no additional benefit in terms of improving wellbeing or mood, show study findings.

Bipolar recovery questionnaire is valid measure

Posted: 11 Apr 2013 05:00 PM PDT

Researchers have devised a bipolar recovery questionnaire that appears to be reliable and valid for assessing personal recovery in patients with bipolar disorder.

High rates of cannabis use in people with mental illnesses

Posted: 11 Apr 2013 05:00 PM PDT

People with mental illnesses have a significantly higher prevalence of cannabis use and cannabis use disorders than mentally healthy individuals, researchers report.

Blood pressure targets shaped by outcome considerations

Posted: 11 Apr 2013 05:00 PM PDT

The risk for different vascular outcomes in patients with hypertension may vary according to the systolic blood pressure target they achieve, research suggests.

PSA test harms outweigh prostate cancer benefits in majority

Posted: 11 Apr 2013 05:00 PM PDT

Men should be warned that the chances of harm from screening with the prostate-specific antigen test outweigh the likelihood of benefit for most men, says the American College of Physicians in a guideline statement on prostate cancer screening.

GERD common in Asian lung disease patients

Posted: 11 Apr 2013 05:00 PM PDT

Results from an Indian study suggest that gastro-esophageal reflux disease is prevalent among Asian patients with chronic obstructive pulmonary disease.

PSA test harms outweigh prostate cancer benefits in majority

Posted: 11 Apr 2013 05:00 PM PDT

Men should be warned that the chances of harm from screening with the prostate-specific antigen test outweigh the likelihood of benefit for most men, says the American College of Physicians in a guideline statement on prostate cancer screening.

Genotoxic properties of nitrous oxide revealed yet again

Posted: 10 Apr 2013 05:00 PM PDT

Nitrous oxide administered to adult patients undergoing major elective open colorectal surgery is associated with DNA damage in peripheral leukocytes, a study finds

Ventral striatal activity possible biomarker for bipolar II disorder

Posted: 10 Apr 2013 05:00 PM PDT

Researchers have observed increased activity in the ventral striatum in response to reward anticipation in patients with bipolar II disorder compared with patients with bipolar I disorder and mentally healthy controls, leading them to suggest that it could be a biomarker for the disorder.

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