Medical News

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• Comorbid anxiety problematic for adolescents with bipolar disorder
• Comorbid anxiety problematic for adolescents with bipolar disorder
• Metacognitive training complements antipsychotic therapy
• Weight loss reduces pediatric exercise-induced bronchoconstriction
• Metacognitive training complements antipsychotic therapy
• Toxicity limits benefits of bevacizumab–erlotinib NSCLC maintenance therapy
• DNA methylation signature marks recurrence in early stage lung cancer
• FDG-PET parameter predicts locally advanced lung cancer survival
• Toxicity limits benefits of bevacizumab–erlotinib NSCLC maintenance therapy
• DNA methylation signature marks recurrence in early stage lung cancer
• FDG-PET parameter predicts locally advanced lung cancer survival

Comorbid anxiety problematic for adolescents with bipolar disorder Posted: 31 Oct 2013 05:00 PM PDT Anxiety disorders are common in children and adolescents with bipolar disorder and adversely affect their outcomes, suggest study findings.

Comorbid anxiety problematic for adolescents with bipolar disorder Posted: 31 Oct 2013 05:00 PM PDT Anxiety disorders are common in children and adolescents with bipolar disorder and adversely affect their outcomes, suggest study findings.

Metacognitive training complements antipsychotic therapy Posted: 31 Oct 2013 05:00 PM PDT Metacognitive training may benefit patients with schizophrenia who only partially respond to antipsychotic treatment, study findings show.

Weight loss reduces pediatric exercise-induced bronchoconstriction Posted: 31 Oct 2013 05:00 PM PDT A study has found that weight loss in overweight and obese children with exercise-induced bronchoconstriction leads to a significant reduction in symptom severity and improved quality of life.

Metacognitive training complements antipsychotic therapy Posted: 31 Oct 2013 05:00 PM PDT Metacognitive training may benefit patients with schizophrenia who only partially respond to antipsychotic treatment, study findings show.

Toxicity limits benefits of bevacizumab–erlotinib NSCLC maintenance therapy Posted: 30 Oct 2013 05:00 PM PDT Two targeted anticancer drugs used together after first-line chemotherapy for advanced stage non-small-cell lung cancer improve progression-free survival, the results of a large, prospective study show.

DNA methylation signature marks recurrence in early stage lung cancer Posted: 30 Oct 2013 05:00 PM PDT An international research team has identified a DNA methylation signature that identifies patients with stage I non-small-cell lung cancer who are at high risk for relapse.

FDG-PET parameter predicts locally advanced lung cancer survival Posted: 30 Oct 2013 05:00 PM PDT High post-treatment concentrations of a radioactive imaging marker are predictive of worse overall survival from inoperable, locally advanced non-small-cell lung cancer, prospective study findings suggest.

Toxicity limits benefits of bevacizumab–erlotinib NSCLC maintenance therapy Posted: 30 Oct 2013 05:00 PM PDT Two targeted anticancer drugs used together after first-line chemotherapy for advanced stage non-small-cell lung cancer improve progression-free survival, the results of a large, prospective study show.

DNA methylation signature marks recurrence in early stage lung cancer Posted: 30 Oct 2013 05:00 PM PDT An international research team has identified a DNA methylation signature that identifies patients with stage I non-small-cell lung cancer who are at high risk for relapse.

FDG-PET parameter predicts locally advanced lung cancer survival Posted: 30 Oct 2013 05:00 PM PDT High post-treatment concentrations of a radioactive imaging marker are predictive of worse overall survival from inoperable, locally advanced non-small-cell lung cancer, prospective study findings suggest.

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• Large, rare CNV burden reduced in bipolar disorder
• Large, rare CNV burden reduced in bipolar disorder
• Self-harm warns of repeated suicide attempt risk in schizophrenia
• Pediatric asthma hospitalizations alert to poor disease management
• Self-harm warns of repeated suicide attempt risk in schizophrenia

Large, rare CNV burden reduced in bipolar disorder Posted: 30 Oct 2013 05:00 PM PDT Large and rare chromosomal copy number variants are uncommon in patients with bipolar disorder, even those with early-onset disease, study findings confirm.

Large, rare CNV burden reduced in bipolar disorder Posted: 30 Oct 2013 05:00 PM PDT Large and rare chromosomal copy number variants are uncommon in patients with bipolar disorder, even those with early-onset disease, study findings confirm.

Self-harm warns of repeated suicide attempt risk in schizophrenia Posted: 30 Oct 2013 05:00 PM PDT Individuals who have attempted suicide and also have a history of self-harm should be thoroughly assessed for psychotic symptoms in order to prevent delayed treatment and the risk for repeated suicide attempts, say researchers.

Pediatric asthma hospitalizations alert to poor disease management Posted: 30 Oct 2013 05:00 PM PDT Researchers from Italy say that the majority of hospitalizations for pediatric asthma reflect inadequate disease management rather than disease severity.

Self-harm warns of repeated suicide attempt risk in schizophrenia Posted: 30 Oct 2013 05:00 PM PDT Individuals who have attempted suicide and also have a history of self-harm should be thoroughly assessed for psychotic symptoms in order to prevent delayed treatment and the risk for repeated suicide attempts, say researchers.

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• Parental bipolar history common in US bipolar patients
• Mood instability shapes psychotic experiences
• Parental bipolar history common in US bipolar patients
• Mood instability shapes psychotic experiences
• Farmyard proximity benefit to respiratory health
• Mood instability shapes psychotic experiences
• Active management boosts patient satisfaction with COPD care

Parental bipolar history common in US bipolar patients Posted: 29 Oct 2013 05:00 PM PDT Research findings suggest that patients with bipolar disorder who reside in the United States have a higher parental incidence of bipolar disorder and depression than those who live in Europe.

Mood instability shapes psychotic experiences Posted: 29 Oct 2013 05:00 PM PDT Mood instability is a prominent feature of psychosis, say researchers who found it was associated with and predicted the presence of psychotic experiences such as paranoid ideation and auditory hallucinations.

Parental bipolar history common in US bipolar patients Posted: 29 Oct 2013 05:00 PM PDT Research findings suggest that patients with bipolar disorder who reside in the United States have a higher parental incidence of bipolar disorder and depression than those who live in Europe.

Mood instability shapes psychotic experiences Posted: 29 Oct 2013 05:00 PM PDT Mood instability is a prominent feature of psychosis, say researchers who found it was associated with and predicted the presence of psychotic experiences such as paranoid ideation and auditory hallucinations.

Farmyard proximity benefit to respiratory health Posted: 29 Oct 2013 05:00 PM PDT Data from the Netherlands indicate that living in close proximity to livestock farms is associated with decreased respiratory morbidity, including asthma, allergic rhinitis, and chronic obstructive pulmonary disease.

Mood instability shapes psychotic experiences Posted: 29 Oct 2013 05:00 PM PDT Mood instability is a prominent feature of psychosis, say researchers who found it was associated with and predicted the presence of psychotic experiences such as paranoid ideation and auditory hallucinations.

Active management boosts patient satisfaction with COPD care Posted: 28 Oct 2013 05:00 PM PDT A disease management program for chronic obstructive pulmonary disease based on the Chronic Care Model leads to greater patient satisfaction with care than standard disease management, a randomized trial suggests.

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• Extra input pays bipolar treatment dividends
• EZH2 protein may aid prognostication in resected NSCLC
• Extra input pays bipolar treatment dividends
• Brain aging extends beyond schizophrenia
• Brain aging extends beyond schizophrenia

Extra input pays bipolar treatment dividends Posted: 28 Oct 2013 05:00 PM PDT Customizing an implementation program to individual practices and providing proactive support improves the adherence of patients with bipolar disorder to Life Goals Collaborative Care, shows a randomized trial.

EZH2 protein may aid prognostication in resected NSCLC Posted: 28 Oct 2013 05:00 PM PDT A protein called "enhancer of zeste homolog-2" is frequently expressed in non-small-cell lung cancer and may have prognostic value following surgical resection, US researchers believe.

Extra input pays bipolar treatment dividends Posted: 28 Oct 2013 05:00 PM PDT Customizing an implementation program to individual practices and providing proactive support improves the adherence of patients with bipolar disorder to Life Goals Collaborative Care, shows a randomized trial.

Brain aging extends beyond schizophrenia Posted: 28 Oct 2013 05:00 PM PDT Accelerated brain aging may be a common feature of psychiatric disorders, say researchers.

Brain aging extends beyond schizophrenia Posted: 28 Oct 2013 05:00 PM PDT Accelerated brain aging may be a common feature of psychiatric disorders, say researchers.

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• Early morning SBP signals silent brain stenosis
• Sore throat clinical score boosts effective antibiotic use
• Current drugs may harbor small-cell lung cancer promise
• Complement protein holds diagnostic, prognostic promise in lung cancer
• Current drugs may harbor small-cell lung cancer promise
• Complement protein holds diagnostic, prognostic promise in lung cancer
• Sore throat clinical score boosts effective antibiotic use
• COPD–asthma overlap heightens exacerbation risk
• Early morning SBP signals silent brain stenosis
• Sexual dysfunction ‘ignored in COPD’
• Nerve-sparing quality boosts urinary recovery after radical prostatectomy

Early morning SBP signals silent brain stenosis Posted: 27 Oct 2013 05:00 PM PDT Ambulatory systolic blood pressure in the early hours of the morning is predictive of asymptomatic intracranial arterial stenosis, the results of a cross-sectional study in China suggest.

Sore throat clinical score boosts effective antibiotic use Posted: 27 Oct 2013 05:00 PM PDT Research published in the BMJ shows that clinical score is as good a guide for antibiotic prescribing as rapid streptococcal antigen detection tests in patients presenting to primary care with sore throat.

Current drugs may harbor small-cell lung cancer promise Posted: 27 Oct 2013 05:00 PM PDT Scientists have identified several existing non-oncology drug classes that may have potential as a treatment for small-cell lung cancer, especially for patients with chemoresistant and metastatic disease.

Complement protein holds diagnostic, prognostic promise in lung cancer Posted: 27 Oct 2013 05:00 PM PDT A complement activation product known as "C4d" may have value as a diagnostic and prognostic biomarker for lung cancer, research suggests.

Current drugs may harbor small-cell lung cancer promise Posted: 27 Oct 2013 05:00 PM PDT Scientists have identified several existing non-oncology drug classes that may have potential as a treatment for small-cell lung cancer, especially for patients with chemoresistant and metastatic disease.

Complement protein holds diagnostic, prognostic promise in lung cancer Posted: 27 Oct 2013 05:00 PM PDT A complement activation product known as "C4d" may have value as a diagnostic and prognostic biomarker for lung cancer, research suggests.

Sore throat clinical score boosts effective antibiotic use Posted: 27 Oct 2013 05:00 PM PDT Research published in the BMJ shows that clinical score is as good a guide for antibiotic prescribing as rapid streptococcal antigen detection tests in patients presenting to primary care with sore throat.

COPD–asthma overlap heightens exacerbation risk Posted: 27 Oct 2013 05:00 PM PDT Patients with chronic obstructive pulmonary disease and concomitant asthma have significantly more exacerbations and hospitalizations than patients with COPD alone, research shows.

Early morning SBP signals silent brain stenosis Posted: 27 Oct 2013 05:00 PM PDT Ambulatory systolic blood pressure in the early hours of the morning is predictive of asymptomatic intracranial arterial stenosis, the results of a cross-sectional study in China suggest.

Sexual dysfunction ‘ignored in COPD’ Posted: 27 Oct 2013 05:00 PM PDT Researchers say that physicians should address sexual issues in patients with chronic obstructive pulmonary disease as a matter of course, after finding that over three-quarters of men with the condition have some level of erectile dysfunction.

Nerve-sparing quality boosts urinary recovery after radical prostatectomy Posted: 27 Oct 2013 05:00 PM PDT The quality of nerve sparing during radical prostatectomy has a significant influence on the recovery of urinary function in men with prostate cancer, research shows.

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• ‘Distinct’ bipolar pathways revealed
• ‘Distinct’ bipolar pathways revealed
• Psychosis prediction model could facilitate early intervention
• COPD telemonitoring ‘costly and ineffective’
• Psychosis prediction model could facilitate early intervention

‘Distinct’ bipolar pathways revealed Posted: 24 Oct 2013 05:00 PM PDT A genetic analysis reported in Nature suggests two mechanisms that could lead to bipolar disorder.

‘Distinct’ bipolar pathways revealed Posted: 24 Oct 2013 05:00 PM PDT A genetic analysis reported in Nature suggests two mechanisms that could lead to bipolar disorder.

Psychosis prediction model could facilitate early intervention Posted: 24 Oct 2013 05:00 PM PDT A integrated model has shown "outstanding" ability to predict the transition to psychosis in clinically high-risk patients, report investigators in Schizophrenia Bulletin.

COPD telemonitoring ‘costly and ineffective’ Posted: 24 Oct 2013 05:00 PM PDT Results of a UK-based study indicate that telemonitoring adds little benefit to the self-management of chronic obstructive pulmonary disease.

Psychosis prediction model could facilitate early intervention Posted: 24 Oct 2013 05:00 PM PDT A integrated model has shown "outstanding" ability to predict the transition to psychosis in clinically high-risk patients, report investigators in Schizophrenia Bulletin.

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• Multifactorial approach needed for early bipolar detection
• Autoimmune link to schizophrenia
• Multifactorial approach needed for early bipolar detection
• Autoimmune link to schizophrenia
• Pediatric asthma hospitalizations alert to poor disease management
• Autoimmune link to schizophrenia
• Autoimmune link to schizophrenia
• BCG asthma effects are lost in adolescence

Multifactorial approach needed for early bipolar detection Posted: 23 Oct 2013 05:00 PM PDT At-risk states for bipolar disorder require a multifaceted approach to be identified and appropriately treated, according to preliminary results from the Dresden High-Risk Project.

Autoimmune link to schizophrenia Posted: 23 Oct 2013 05:00 PM PDT Patients with schizophrenia have an increased risk for developing autoimmune diseases, especially if they contract an infection, shows a registry-based study.

Multifactorial approach needed for early bipolar detection Posted: 23 Oct 2013 05:00 PM PDT At-risk states for bipolar disorder require a multifaceted approach to be identified and appropriately treated, according to preliminary results from the Dresden High-Risk Project.

Autoimmune link to schizophrenia Posted: 23 Oct 2013 05:00 PM PDT Patients with schizophrenia have an increased risk for developing autoimmune diseases, especially if they contract an infection, shows a registry-based study.

Pediatric asthma hospitalizations alert to poor disease management Posted: 23 Oct 2013 05:00 PM PDT Researchers from Italy say that the majority of hospitalizations for pediatric asthma reflect inadequate disease management rather than disease severity.

Autoimmune link to schizophrenia Posted: 23 Oct 2013 05:00 PM PDT Patients with schizophrenia have an increased risk for developing autoimmune diseases, especially if they contract an infection, shows a registry-based study.

Autoimmune link to schizophrenia Posted: 23 Oct 2013 05:00 PM PDT Patients with schizophrenia have an increased risk for developing autoimmune diseases, especially if they contract an infection, shows a registry-based study.

BCG asthma effects are lost in adolescence Posted: 22 Oct 2013 05:00 PM PDT Any beneficial effects of the neonatal Bacillus Calmette–Guérin vaccine on childhood asthma symptoms and outcomes are likely to be transient, disappearing by adolescence, show follow-up findings from the Manchester Community Asthma Study.

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