Friday, December 31, 2010

iPhone Medical News

iPhone Medical News


The Best of Medgadget 2010

Posted: 31 Dec 2010 12:23 AM PST

With the year 2010 coming to a close, we've composed a list of the 10 best new medical technologies and devices of the past twelve months. As part of our job as Medgadget editors, we look at thousands of new products, news stories and press releases and from these we distill the most noteworthy for your reading pleasure. This year our efforts resulted in a total of approximately 1800 posts, so there was no lack of material to choose from for this best of list. Many new devices and technologies were creative, innovative, expected to make a long-lasting impact, and some others were plain silly. Here, in no particular order, are those that clearly stood out this year in a positive way:


GE V-scan Portable Ultrasound
In February, GE introduced its Vscan, a pocket-sized ultrasound device. It changed the definition of portable ultrasound, which previously referred to rather large laptop-sized devices. Despite its small dimensions, the Vscan includes features such as power-doppler, and the device is powerful enough for most applications, including emergency medicine, cardiac and obstetric ultrasounds. Although it is still far too expensive to give out to every doctor in those specialties, it is not hard to envision it becoming a tool as indispensable as the stethoscope one day.


The iPad
The hype around the iPad has not gone unnoticed in the medical world. Previous (medical grade) tablets did not make a significant impact. However, the iPad has sparked a rich ecosystem of medical apps and even some add-on medical devices. We had over 50 posts referring to the iPad one way or another. Highlights include the introduction, the first clinical tests, the first appearance in an operating theater and several great apps including reference apps, radiology viewers and electronic health records. With the iPad 2 expected in 2011 we expect no end to to the stream of news about this wonderful device. Also tablets from competing manufacturers are starting to mature and might stiffen up the competition in the next year.

Artificial life
In May, the J. Craig Venter Institute announced it had for the first time replaced the DNA of a bacterium with a complete set of synthetic DNA. This was the result of 15 years of work, with the aim of creating a living, replicating cell. The process currently still means recreating an existing genome rather than designing one from scratch, and still needs existing cells to put the DNA into. Meanwhile, some living tissues were connected to chips in order to better study them. In June, a living and breathing lung on a chip was announced, with the researchers working on getting other organs connected as well. Other scientists managed to grow individual neurons on microchips and neurons within neural networks got pinned down for study.


Retinal Implant
In March, the company Retina Implant AG from Reutlingen, Germany reported the first results of human trials with the firm's subretinal electronic chips in blind volunteers. Implantation was successful in 11 patients without any adverse events. In November actual results of the performance of the implant itself in the first three volunteers were published. The previously blind persons could locate bright objects on a dark table and one of them could name objects like a fork or knife and differentiate between various kinds of fruit. After the pacemaker and the cochlear implant, this may well be the next electronic device to be widely implanted in patients.

Hemolung Respiratory Dialysis

Mechanical ventilation is often a life-saving intervention in critically-ill patients. However, it has some serious drawbacks, including the need for sedation, the risk of ventilator associated pneumonia, and intubation or tracheostomy related complications. ALung Technologies' Hemolung overcomes many of these drawbacks by using dialysis to perform respiratory gas exchange in a process similar to extracorporeal membrane oxygenation. During therapy, the patient can stay awake, allowing him to eat and communicate. In February, the first patient was successfully treated with the device, and clinical trials are currently underway. If successful, this could revolutionize the practice of medicine in the ICU.


Ardian Symplicity
The best innovations are simple and effective, and these criteria both seem to apply to the Symplicity catheter system. In addition, it targets one of the most common chronic conditions affecting the western population: hypertension. By reducing or eliminating the sympathetic innervation of the renal arteries, it reduces both the pathologic central sympathetic drive to the kidney and the renal contribution to central sympathetic hyperactivity. In an initial clinical trial, the procedure reduced blood pressure by 30/10 mmHg without causing any serious complications. A one time catheter treatment versus lifetime-long treatment with antihypertensive drugs might be a realistic choice soon.


Telemedicine
Telemedicine has been a promise for many years, slowly coming to fruition. This year some significant leaps were made. Airstrip technologies, which previously released a remote obstetric monitoring app, in August released remote critical care and cardiology monitoring solutions for the iPhone. Basically, it gives you a vital signs monitor for any connected ICU or cardiac patient right in your pocket. Meanwhile, Littmann keeps improving its teleauscultation offering, adding scope-to-scope teleauscultation. On the treatment front, we saw the first remote cardiac catheterization, transcontinental anesthesia and all-robotic surgery and anesthesia.


Magnetic Resonance Imaging
MRI is one of the most advanced diagnostic techniques in clinical use. It is still undergoing rapid development giving rise to new applications, better image quality and shorter acquisition times. A few of the highlights this year were real-time MRI of moving organs, further digitalization of the hardware, combined PET/MRI devices and, as the most curious of all, a live birth within an MRI scanner.


Skin Bioprinting for Burn Wounds
Burn wounds are something that modern medicine has not yet found many effective treatments for yet. However, this year we saw a device that could print skin grafts to cover the burn wounds, accelerating recovery and minimizing scar tissue. The prototype device was tested on artificially created full-thickness skin wounds in nude mice, resulting in much faster wound recovery.


General Purpose Pathogen Detector
Identifying the causative organism of an infection often takes several days, while broad spectrum antibiotics are given in the meantime. The Lawrence Livermore Microbial Detection Array might change all that. It promises to detect about 2,000 viruses and 900 bacteria within 24 hours. Current methods are limited to detecting any from about 50 organisms in one test. And the next-generation of the device is already in development, with 2.1 million probes, able to detect thousands of bacteria and viruses and in addition thousands of fungi and about 75 protozoa.

That's it! If we missed anything, the comments section is open for your additions. With this list, we wrap up the year 2010. In 2011 we will be back with more news and some major improvements to our website. We wish you all a happy new year!



Thursday, December 30, 2010

Medical News

Medical News


Psoriasis ‘not independent CVD risk factor’

Posted: 30 Dec 2010 04:00 PM PST

Patients with moderate-to-severe psoriasis without cardiovascular disease or its traditional risk factors have normal endothelial function, a UK study shows.

Dermoscopy useful for distinguishing psoriasis from seborrheic dermatitis

Posted: 30 Dec 2010 04:00 PM PST

Scalp psoriasis and seborrheic dermatitis can be differentiated by looking at vascular patterns using dermoscopy, report researchers.

GERD prevalence does not increase with age

Posted: 30 Dec 2010 04:00 PM PST

Results from a systematic review suggest that the prevalence of gastroesophageal reflux disease does not increase with age, but that esophageal symptoms of sufferers become more severe as they get older.

Wednesday, December 29, 2010

Medical News

Medical News


Minimal important difference identified for endurance shuttle walking test

Posted: 29 Dec 2010 04:00 PM PST

Endurance shuttle walking performance appears to be a valid form of exercise testing in patients with chronic obstructive pulmonary disease, research suggests.

Tuesday, December 28, 2010

Medical News

Medical News


Racial bias in contribution of biologic factors to asthma severity

Posted: 28 Dec 2010 04:00 PM PST

Asthma severity in Black patients is tightly linked to family history and presence of atopy unlike that in White patients, a study has shown.

Infection with Helicobacter pylori increases insulin resistance

Posted: 28 Dec 2010 04:00 PM PST

Study results show that Helicobacter pylori infection increases insulin resistance through elevation of fetuin A, which could indicate a link with diabetes.

Sunday, December 26, 2010

Medical News

Medical News


ABO blood group linked to pancreatic cancer risk

Posted: 26 Dec 2010 04:00 PM PST

Patients with pancreatic cancer are significantly more likely to be blood group A than O, show results from a US study.

ABO blood group linked to pancreatic cancer risk

Posted: 26 Dec 2010 04:00 PM PST

Patients with pancreatic cancer are significantly more likely to be blood group A than O, show results from a US study.

‘Real world’ executive function test proposed for schizophrenia

Posted: 23 Dec 2010 04:00 PM PST

A test that assesses schizophrenia patients' ability to do grocery shopping is a good measure of executive function in a natural environment, say researchers.

Clinicians show heuristic bias in bipolar disorder diagnosis

Posted: 23 Dec 2010 04:00 PM PST

Only 40% of clinicians make a correct diagnosis of bipolar disorder when presented with a definitive case and are subject to heuristic bias, a survey shows.

Empathy deteriorates with illness progression in schizophrenia

Posted: 22 Dec 2010 04:00 PM PST

Patients with first-episode psychosis show relatively preserved empathy, which appears to deteriorate with progression to more chronic schizophrenia, perhaps as a consequence of cognitive decline, study results show.

Bipolar disorder with BPD marked by high aggression and impulsivity

Posted: 22 Dec 2010 04:00 PM PST

Bipolar disorder patients with comorbid borderline personality disorder show a heightened level of impulsivity and aggression as well as a markedly elevated rate of suicide attempts relative to those with bipolar disorder alone, study results show.

Stigma, empowerment, social network influence QoL in schizophrenia

Posted: 21 Dec 2010 04:00 PM PST

Schizophrenia patients with a poor social network experience stigma and a lack of empowerment that results in depression and, in turn, in poor quality of life, study results show.

Exercise improves HF survival by reducing depression

Posted: 21 Dec 2010 04:00 PM PST

Structured exercise training may reduce long-term mortality risk among heart failure patients by alleviating depressive symptoms, US researchers report.

Psychological disability presents early in affective disorders

Posted: 21 Dec 2010 04:00 PM PST

Functional disability is already pronounced in young people in the early stages of affective and anxiety disorders, and deteriorates with advancing clinical stage, study results show.

Social anxiety an ‘independent domain’ in psychotic disorders

Posted: 20 Dec 2010 04:00 PM PST

Social anxiety is strongly correlated with self-esteem and active withdrawal in patients with psychotic disorders and is not simply a by-product of positive and negative symptoms, study results show.

Invasive therapy benefits elderly AMI patients

Posted: 20 Dec 2010 04:00 PM PST

Results from a large Polish study indicate that invasive treatment of acute myocardial infarction complicated by cardiogenic shock in patients aged 75 years or older reduces 6-month mortality risk compared with noninvasive treatment.

White matter integrity affects functional outcome in bipolar disorder

Posted: 20 Dec 2010 04:00 PM PST

The functional outcome of patients with bipolar disorder is influenced by cognitive performance, clinical course, and white matter volume, research shows.

Thursday, December 23, 2010

Medical News

Medical News


Centrally adjudicated ultrasound not always suitable for DVT screening

Posted: 23 Dec 2010 04:00 PM PST

Centrally adjudicated complete compression ultrasound may not be suitable to screen for asymptomatic deep vein thrombosis early after major orthopedic surgery, according to German researchers.

Fried fish adds to Stroke Belt woes

Posted: 23 Dec 2010 04:00 PM PST

Residents of the "Stroke Belt" eat more fried fish than people in the rest of the USA and have lower than recommended intake of nonfried fish, shows an analysis of the REGARDS study.

Cerebrovascular disease highly prevalent in Type 2 diabetics

Posted: 23 Dec 2010 04:00 PM PST

Atherosclerotic plaques are present in the vast majority of patients with Type 2 diabetes mellitus, a state-of-the-art imaging study has found.

Clinicians show heuristic bias in bipolar disorder diagnosis

Posted: 23 Dec 2010 04:00 PM PST

Only 40% of clinicians make a correct diagnosis of bipolar disorder when presented with a definitive case and are subject to heuristic bias, a survey shows.

‘Real world’ executive function test proposed for schizophrenia

Posted: 23 Dec 2010 04:00 PM PST

A test that assesses schizophrenia patients' ability to do grocery shopping is a good measure of executive function in a natural environment, say researchers.

Sarcosine cannot predict prostate cancer aggression or recurrence

Posted: 23 Dec 2010 04:00 PM PST

Levels of the metabolite sarcosine cannot reliably predict the aggressiveness of prostate cancer, nor recurrence-free survival after surgical treatment, study results show.

Breast cancer brachytherapy on the increase

Posted: 23 Dec 2010 04:00 PM PST

The use of brachytherapy alone after breast conserving surgery for breast cancer has increased significantly in recent years, US study results show.

Sarcosine cannot predict prostate cancer aggression or recurrence

Posted: 23 Dec 2010 04:00 PM PST

Levels of the metabolite sarcosine cannot reliably predict the aggressiveness of prostate cancer, nor recurrence-free survival after surgical treatment, study results show.

Estradiol implicated in link between fiber intake and lipoproteins

Posted: 23 Dec 2010 04:00 PM PST

The beneficial impact of dietary fiber intake on lipid levels may be partly mediated by estradiol, a study of healthy premenopausal women has found.

Statins ‘may improve prognosis’ in renovascular disease

Posted: 23 Dec 2010 04:00 PM PST

The use of statins is associated with a reduced risk for vascular events among elderly patients with renovascular disease, a cohort study has found.

LSM detects undiagnosed chronic liver disease

Posted: 23 Dec 2010 04:00 PM PST

Study findings show that liver stiffness measurement can detect undiagnosed chronic liver disease in apparently healthy individuals, with the added benefit of a 100% positive predictive value for cirrhosis screening.

A-FABP4 levels raised in early diabetic nephropathy

Posted: 23 Dec 2010 04:00 PM PST

High blood levels of adipocyte fatty acid binding protein-4 are associated with early nephropathy in patients with Type 2 diabetes, study findings suggest.

Cerebrovascular disease highly prevalent in Type 2 diabetics

Posted: 23 Dec 2010 04:00 PM PST

Atherosclerotic plaques are present in the vast majority of patients with Type 2 diabetes mellitus, a state-of-the-art imaging study has found.

Snow shoveling poses cardiac risk

Posted: 23 Dec 2010 04:00 PM PST

Results from a 17-year US study indicate that snow shoveling may precipitate adverse cardiac events, especially among men aged 55 years or older.

AHA/ACC/ESC update AF guidelines

Posted: 23 Dec 2010 04:00 PM PST

The latest atrial fibrillation guidelines from the American College of Cardiology, American Heart Association, and European Society of Cardiology suggest that strict heart rate control in patients with the arrhythmia provides no benefit over a more lenient approach.

Breast cancer brachytherapy on the increase

Posted: 23 Dec 2010 04:00 PM PST

The use of brachytherapy alone after breast conserving surgery for breast cancer has increased significantly in recent years, US study results show.

PON1 determines clopidogrel responsiveness

Posted: 22 Dec 2010 04:00 PM PST

European researchers have identified the enzyme paraoxonase-1 as a major determinant of the bioactivation, and thus the clinical efficacy, of clopidogrel.

Prostate cancer risk calculator underestimates high-grade disease

Posted: 22 Dec 2010 04:00 PM PST

Caution is required when applying the prostate cancer risk calculator to patients with suspected prostate cancer as it may underestimate their risk for high-grade disease, warn US researchers.

PSA bounce after brachytherapy do not always indicate biochemical failure

Posted: 22 Dec 2010 04:00 PM PST

Prostate cancer patients treated with brachytherapy should be informed of the potential for a prostate-specific antigen "bounce" after treatment, to "allay unnecessary worry" that they are experiencing recurrence of disease, say Australian researchers.

EBV may be linked to more aggressive breast cancers

Posted: 22 Dec 2010 04:00 PM PST

Epstein-Barr virus is detectable in up to one third of breast cancers, and its presence is associated with more aggressive disease, show French study results.

EBV may be linked to more aggressive breast cancers

Posted: 22 Dec 2010 04:00 PM PST

Epstein-Barr virus is detectable in up to one third of breast cancers, and its presence is associated with more aggressive disease, show French study results.

Electronic medical records could help identify patients at risk for prostate cancer

Posted: 21 Dec 2010 04:00 PM PST

Electronic medical records could improve the identification of men at risk for developing prostate cancer by triggering an evaluation in patients with identifiable risk factors, study result show.

Social wellbeing linked to improved breast cancer outcome

Posted: 21 Dec 2010 04:00 PM PST

Social wellbeing in the first 6 months after a breast cancer diagnosis is significantly associated with a decreased risk for recurrence and death from the disease after treatment, research shows.

Risk factor stratification indicates outcome in prostate surveillance patients

Posted: 20 Dec 2010 04:00 PM PST

Risk factor stratification, incorporating clinical factors available at diagnostic and follow-up biopsies, can indicate the likelihood of disease progression in prostate cancer patients treated with active surveillance, say researchers.

High BED prostate brachytherapy yields excellent long-term outcomes

Posted: 20 Dec 2010 04:00 PM PST

Receiving a high biologically effective dose during treatment for prostate cancer with brachytherapy results in excellent long-term survival, show findings of a 12-year study.

Weight lifting does not increase breast cancer-related lymphedema

Posted: 20 Dec 2010 04:00 PM PST

A program of slowly progressive weight lifting does not increase the incidence of lymphedema among breast cancer survivors, US study findings indicate.

Regulatory agencies announce bevacizumab decision

Posted: 19 Dec 2010 04:00 PM PST

The European Medicines Agency has confirmed that bevacizumab, used in combination with the taxane paclitaxel remains a valuable treatment option for patients with metastatic breast cancer.