Medical News

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• Quality of life scale devised specifically for bipolar disorder
• Neurologic soft signs in schizophrenia show strong clinical correlates
• CEUS shows high diagnostic accuracy for assessing acute pancreatitis
• Breathomics may aid pulmonary embolism diagnosis
• Depressive symptoms independently predict incident stroke
• Tumor-specific characteristics at surgery predict recurrence-free survival
• Tumor-specific characteristics at surgery predict recurrence-free survival
• Research confirms obesity is poor prognostic indicator for breast cancer
• <i>FTO</i> gene may increase risk for CVD in White women
• High activity levels reduce weight gain during transition to middle age
• <i>TCF7L2</i> variants have adverse effect on pancreatic β-cell function
• Low peripheral nerve conduction linked to diabetic complications
• [¹²³I]MIBG imaging predicts adverse outcomes after STEMI
• Small changes in troponin I levels indicate poor HF outcome
• Research confirms obesity is poor prognostic indicator for breast cancer
• PSA doubling time confirmed as predictor of mortality after prostatectomy
• Cancer-inhibiting qualities of pomegranate revealed
• TNXL2 key regulator of breast cancer cell growth
• PCA3 predicts prostate tumor volume and could indicate AS suitability
• Circulating tumor cells have prognostic value in early breast cancer
• PSA nadir, doubling time predict prognosis after prostate cancer ADMT
• Trial results have no impact on postprostatectomy radiation recommendations
• Pregnant breast cancer patients should receive standard treatment

Quality of life scale devised specifically for bipolar disorder Posted: 16 Dec 2010 04:00 PM PST Researchers have developed a specific scale for measuring Quality of Life in Bipolar Disorder, following a 4-year program of research involving patients in the process.

Neurologic soft signs in schizophrenia show strong clinical correlates Posted: 16 Dec 2010 04:00 PM PST Patients with schizophrenia show subtle neurologic deficits, known as soft signs, which comprise four factors that have distinct clinical correlations, study results demonstrate.

CEUS shows high diagnostic accuracy for assessing acute pancreatitis Posted: 16 Dec 2010 04:00 PM PST Study findings suggest that contrast-enhanced ultrasound has a high diagnostic accuracy for evaluating the severity of pancreatitis, and can aid the assessment of pancreatic necrosis and pancreatic complications of acute pancreatitis.

Breathomics may aid pulmonary embolism diagnosis Posted: 15 Dec 2010 04:00 PM PST Exhaled breath molecular profiling allows non-invasive discrimination between patients with and without pulmonary embolism, Dutch researchers report.

Depressive symptoms independently predict incident stroke Posted: 15 Dec 2010 04:00 PM PST Both memory deficits and depressive symptoms are independently associated with an increased risk for stroke, US researchers have shown.

Tumor-specific characteristics at surgery predict recurrence-free survival Posted: 15 Dec 2010 04:00 PM PST A high Gleason score and pathological stage, tumor volume, and the presence of lymph node invasion are all predictive of biochemical recurrence after treatment with robot-assisted radical prostatectomy for prostate cancer, show study results.

Tumor-specific characteristics at surgery predict recurrence-free survival Posted: 15 Dec 2010 04:00 PM PST A high Gleason score and pathological stage, tumor volume, and the presence of lymph node invasion are all predictive of biochemical recurrence after treatment with robot-assisted radical prostatectomy for prostate cancer, show study results.

Research confirms obesity is poor prognostic indicator for breast cancer Posted: 15 Dec 2010 04:00 PM PST Obesity is independently associated with an increased risk for developing distant metastases and death, but not locoregional recurrence, among patients treated for breast cancer, Danish research shows.

<i>FTO</i> gene may increase risk for CVD in White women Posted: 15 Dec 2010 04:00 PM PST US researchers show that carriers of a high-risk variant of the Fat-Mass and Obesity-Associated gene have an increased risk for developing cardiovascular disease, compared with non-carriers.

High activity levels reduce weight gain during transition to middle age Posted: 15 Dec 2010 04:00 PM PST Weight gain during the transition from young adulthood to middle age may be reduced by maintaining high activity levels through young adulthood, say US researchers who found the effect was particularly marked in women.

<i>TCF7L2</i> variants have adverse effect on pancreatic β-cell function Posted: 15 Dec 2010 04:00 PM PST Type 2 diabetic carriers of the risk alleles of two variants of the transcription factor 7-like 2 gene have reduced pancreatic β-cell function, report researchers.

Low peripheral nerve conduction linked to diabetic complications Posted: 15 Dec 2010 04:00 PM PST Patients with Type 1 diabetes who have low peripheral nerve conduction have increased risk for microvascular complications and are more likely to have high glycated hemoglobin and long duration of diabetes, say researchers.

[<sup>123</sup>I]MIBG imaging predicts adverse outcomes after STEMI Posted: 15 Dec 2010 04:00 PM PST ST-elevation myocardial infarction patients with a high washout rate – determined by [123I]m-iodobenzylguanidine scintigraphy – are at increased risk for major adverse cardiac events, Japanese researchers report.

Small changes in troponin I levels indicate poor HF outcome Posted: 15 Dec 2010 04:00 PM PST Even a small rise in troponin I levels may increase the 90-day death and readmission risk among patients with decompensated heart failure, US study findings indicate.

Research confirms obesity is poor prognostic indicator for breast cancer Posted: 15 Dec 2010 04:00 PM PST Obesity is independently associated with an increased risk for developing distant metastases and death, but not locoregional recurrence, among patients treated for breast cancer, Danish research shows.

PSA doubling time confirmed as predictor of mortality after prostatectomy Posted: 14 Dec 2010 04:00 PM PST The time it takes for a man's prostate-specific antigen level to double after radical prostatectomy can be an early indication of whether he is at increased risk for overall or prostate cancer-specific mortality, say researchers.

Cancer-inhibiting qualities of pomegranate revealed Posted: 14 Dec 2010 04:00 PM PST US researchers have identified which elements of pomegranate juice inhibit prostate cancer cell migration, and could therefore offer potential in developing new treatments for the disease.

TNXL2 key regulator of breast cancer cell growth Posted: 14 Dec 2010 04:00 PM PST The redox protein thioredoxin-like 2 controls the growth and metastasis of human breast cancer cells by regulating levels of reactive oxygen species and nuclear factor kappa B activity, study findings indicate.

PCA3 predicts prostate tumor volume and could indicate AS suitability Posted: 13 Dec 2010 04:00 PM PST Prostate cancer patients' urinary prostate cancer antigen 3 scores are strongly indicative of tumor volume, and could be a useful marker of suitability for treatment with active surveillance, study findings show.

Circulating tumor cells have prognostic value in early breast cancer Posted: 13 Dec 2010 04:00 PM PST Just one circulating tumor cell in the blood before chemotherapy may double the risk for disease recurrence and death after treatment among women with early stage breast cancer, study findings indicate.

PSA nadir, doubling time predict prognosis after prostate cancer ADMT Posted: 12 Dec 2010 04:00 PM PST Reaching a prostate-specific antigen nadir of 4 ng/ml or above and experiencing a doubling time of less than 10 months both raise the risk for death from prostate cancer after treatment with androgen deprivation monotherapy, report researchers.

Trial results have no impact on postprostatectomy radiation recommendations Posted: 12 Dec 2010 04:00 PM PST The publication of trial results showing improved biochemical disease-free survival in men treated with radiotherapy after prostatectomy for prostate cancer has not increased recommendations for this therapy combination, report researchers.

Pregnant breast cancer patients should receive standard treatment Posted: 12 Dec 2010 04:00 PM PST Pregnant women with breast cancer should be treated as closely as possible to standard recommendations, said researchers at the 33rd Annual Cancer Therapy and Research Center–American Association for Cancer Research San Antonio Breast Cancer Symposium, held in Texas, USA.

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