Medical News

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• Highly sensitive troponin assay does not improve PE diagnosis
• NSQIP database reveals post-CEA stroke risk factors
• Adalimumab shows superior benefit-risk profile for psoriasis
• Mitochondrial DNA mutations associated with prostate cancer, elevated PSA
• Gene fusion markers in urine could mean novel non-invasive prostate cancer test
• Mitochondrial DNA mutations associated with prostate cancer, elevated PSA
• Gene fusion markers in urine could mean novel non-invasive prostate cancer test
• Weight change during chemotherapy affects breast cancer prognosis
• High BMI linked to all-cause mortality
• LDL subclass patterns may be misleading
• Preterm birth increases risk for Type 2 diabetes in later life
• Type 1 diabetes risk in children increased by enteroviral infection
• FFR-guided PCI has clinical and economic benefits
• PCI as successful with left, right radial artery approach
• Weight change during chemotherapy affects breast cancer prognosis
• Joint replacement higher risk for pulmonary hypertension patients
• Etomidate does not increase hospital stays for sepsis patients
• Post-trauma fatal pulmonary embolism rare, but often preventable
• Tube depth best guide to rule out endobronchial intubation

Highly sensitive troponin assay does not improve PE diagnosis Posted: 02 Dec 2010 04:00 PM PST Using a high-sensitivity troponin T assay does not improve discrimination between patients with and without pulmonary embolism compared with conventional D-dimer testing plus pretest probability assessment, UK researchers report.

NSQIP database reveals post-CEA stroke risk factors Posted: 02 Dec 2010 04:00 PM PST Factors including kidney disease and declining functional status predict which patients are likely to suffer stroke or die after carotid endarterectomy, shows an analysis of the NSQIP database.

Adalimumab shows superior benefit-risk profile for psoriasis Posted: 02 Dec 2010 04:00 PM PST Adalimumab has a superior benefit-risk profile to that of methotrexate, analysis of data from the CHAMPION trial shows.

Mitochondrial DNA mutations associated with prostate cancer, elevated PSA Posted: 02 Dec 2010 04:00 PM PST Somatic mutations in the mitochondrial genome are frequent in prostate cancer patients, show study results from Austrian researchers.

Gene fusion markers in urine could mean novel non-invasive prostate cancer test Posted: 02 Dec 2010 04:00 PM PST Detecting urine-specific markers of TMPRSS2 and ERG gene fusion may reliably identify men with prostate cancer, report Canadian researchers.

Mitochondrial DNA mutations associated with prostate cancer, elevated PSA Posted: 02 Dec 2010 04:00 PM PST Somatic mutations in the mitochondrial genome are frequent in prostate cancer patients, show study results from Austrian researchers.

Gene fusion markers in urine could mean novel non-invasive prostate cancer test Posted: 02 Dec 2010 04:00 PM PST Detecting urine-specific markers of TMPRSS2 and ERG gene fusion may reliably identify men with prostate cancer, report Canadian researchers.

Weight change during chemotherapy affects breast cancer prognosis Posted: 02 Dec 2010 04:00 PM PST Women whose weight changes by more than 5% during breast cancer chemotherapy are twice as likely to suffer recurrence of or die from the disease than women who maintain a stable weight, French researchers report.

High BMI linked to all-cause mortality Posted: 02 Dec 2010 04:00 PM PST Overweight and obesity are associated with increased risk for all-cause mortality, a US study has found.

LDL subclass patterns may be misleading Posted: 02 Dec 2010 04:00 PM PST Using increases in the proportions of smaller, more dense, low-density lipoprotein cholesterol to assess risk for coronary heart disease may be misleading if interpreted without considering other lipid effects.

Preterm birth increases risk for Type 2 diabetes in later life Posted: 02 Dec 2010 04:00 PM PST Being born before 35 weeks of gestation increases the risk for developing Type 2 diabetes in later life, report researchers.

Type 1 diabetes risk in children increased by enteroviral infection Posted: 02 Dec 2010 04:00 PM PST Enterovirus infection may increase the risk for progression from islet autoimmunity to Type 1 diabetes, suggest results from the DAISY study.

FFR-guided PCI has clinical and economic benefits Posted: 02 Dec 2010 04:00 PM PST Results from the FAME study suggest that percutaneous coronary intervention guided by fractional flow reserve costs less and produces better outcomes at 1 year than guidance by angiography.

PCI as successful with left, right radial artery approach Posted: 02 Dec 2010 04:00 PM PST Percutaneous coronary intervention can be performed with similar ease and efficacy via the right or left radial artery, study results indicate.

Weight change during chemotherapy affects breast cancer prognosis Posted: 02 Dec 2010 04:00 PM PST Women whose weight changes by more than 5% during breast cancer chemotherapy are twice as likely to suffer recurrence of or die from the disease than women who maintain a stable weight, French researchers report.

Joint replacement higher risk for pulmonary hypertension patients Posted: 02 Dec 2010 04:00 PM PST Patients who have pulmonary hypertension are at an increased risk for dying in hospital after undergoing primary total hip or knee arthroplasty, report researchers.

Etomidate does not increase hospital stays for sepsis patients Posted: 02 Dec 2010 04:00 PM PST Using etomidate for rapid sequence intubation induction in patients with suspected sepsis does not appear to increase their length of hospital stay, shows a randomized trial.

Post-trauma fatal pulmonary embolism rare, but often preventable Posted: 02 Dec 2010 04:00 PM PST Researchers say that pulmonary embolism after major trauma accounts for more than one in 10 fatalities, with half of these potentially preventable.

Tube depth best guide to rule out endobronchial intubation Posted: 02 Dec 2010 04:00 PM PST Endotracheal tube insertion depth, to 20 cm in women and 22 cm in men, is more reliable than auscultation for excluding inadvertent endobronchial intubation, especially if the clinician is inexperienced, research shows.

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