Medical News

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• Bipolar disorder ‘significantly underdiagnosed’ in primary care
• mfVEPs abnormal in schizophrenia patients
• Thrombosis recurrence risk greater in men than women
• Inequalities highlighted in English stroke care
• Bevacizumab linked to fatal outcome in cancer patients
• Paclitaxel plus bevacizumab extends PFS in ovarian cancer
• DMPA reduces bone mineral density, but is reversible
• Discrimination could affect contraception choice
• Paclitaxel plus bevacizumab extends PFS in ovarian cancer
• Biomarkers identified for macrosomia at birth after diabetic pregnancy
• Concentration and mood most affect work and relationships during menopause
• Absolute benefits of statins greater for older patients
• Mediterranean dietary pattern may reduce obesity
• Use of handheld device during CPR improves 1-year survival
• High prorenin may predict pre-eclampsia in Type 1 diabetic women
• Slow HR recovery predicts silent myocardial ischemia in Type 2 diabetics
• Use of handheld device during CPR improves 1-year survival

Bipolar disorder ‘significantly underdiagnosed’ in primary care Posted: 28 Feb 2011 04:00 PM PST Results from a UK study suggest that a significant proportion of patients treated for depression in primary care may have undiagnosed bipolar disorder.

mfVEPs abnormal in schizophrenia patients Posted: 28 Feb 2011 04:00 PM PST The latency of multifocal visual-evoked potentials is prolonged and amplitude reduced in patients with schizophrenia relative to mentally healthy individuals, research shows.

Thrombosis recurrence risk greater in men than women Posted: 27 Feb 2011 04:00 PM PST Men have approximately twice the risk of women for recurrent venous thromboembolism after an initial unprovoked event, results of a systematic review and meta-analysis show.

Inequalities highlighted in English stroke care Posted: 27 Feb 2011 04:00 PM PST An analysis of the South London Stroke Register has revealed improving acute stroke treatment over a 14-year period, but persisting inequalities in care.

Bevacizumab linked to fatal outcome in cancer patients Posted: 27 Feb 2011 04:00 PM PST The addition of bevacizumab to concurrent chemo- or biological therapy is associated with an increased risk for fatal adverse events in cancer patients, a meta-analysis of randomized controlled trials shows.

Paclitaxel plus bevacizumab extends PFS in ovarian cancer Posted: 27 Feb 2011 04:00 PM PST Adding a bi-weekly dose of bevacizumab—an angiogenesis inhibitor—to weekly paclitaxel treatment for recurrent epithelial ovarian cancer significantly improves progression-free survival compared with paclitaxel treatment alone, report US researchers.

DMPA reduces bone mineral density, but is reversible Posted: 27 Feb 2011 04:00 PM PST Women's bone mineral density drops during depot medroxyprogesterone contraception use, but the effect is reversible, report Chinese researchers.

Discrimination could affect contraception choice Posted: 27 Feb 2011 04:00 PM PST Perceived racial, economic, and gender discrimination could negatively impact a woman's use of contraception, shows analysis of the Contraceptive CHOICE Project results.

Paclitaxel plus bevacizumab extends PFS in ovarian cancer Posted: 27 Feb 2011 04:00 PM PST Adding a bi-weekly dose of bevacizumab—an angiogenesis inhibitor—to weekly paclitaxel treatment for recurrent epithelial ovarian cancer significantly improves progression-free survival compared with paclitaxel treatment alone, report US researchers.

Biomarkers identified for macrosomia at birth after diabetic pregnancy Posted: 27 Feb 2011 04:00 PM PST Birthweight above the 90th centile can be predicted by first trimester levels of the placental protein biomarkers PAPP-A, ADAM12, PP13, and PIGF in women with pregestational Type-1 and Type-2 diabetes, report researchers.

Concentration and mood most affect work and relationships during menopause Posted: 27 Feb 2011 04:00 PM PST The factors that commonly interfere in working life and relationships during the menopausal transition are perceived health, stress, depressed mood, and difficulty concentrating, shows an analysis of the Seattle Midlife Women's Health Study.

Absolute benefits of statins greater for older patients Posted: 27 Feb 2011 04:00 PM PST Study findings suggest that statin therapy is more effective in reducing the risk for major cardiovascular events in older than younger patients at moderate risk for cardiovascular disease.

Mediterranean dietary pattern may reduce obesity Posted: 27 Feb 2011 04:00 PM PST Adherence to a traditional Mediterranean diet is associated with reduced obesity and abdominal adiposity, research shows.

Use of handheld device during CPR improves 1-year survival Posted: 27 Feb 2011 04:00 PM PST Using active compression-decompression cardiopulmonary resuscitation with augmented negative intrathoracic pressure may increase the 1-year survival of patients who experience out-of-hospital cardiac arrest, US study findings suggest.

High prorenin may predict pre-eclampsia in Type 1 diabetic women Posted: 27 Feb 2011 04:00 PM PST Pregnant women with Type 1 diabetes who have high levels of prorenin, a component of the renin angiotensin system, are more likely to develop pre-eclampsia than women with lower prorenin levels, study findings suggest.

Slow HR recovery predicts silent myocardial ischemia in Type 2 diabetics Posted: 27 Feb 2011 04:00 PM PST A slow heart rate recovery after exercise is associated with silent myocardial ischemia in patients with Type 2 diabetes, report researchers.

Use of handheld device during CPR improves 1-year survival Posted: 27 Feb 2011 04:00 PM PST Using active compression-decompression cardiopulmonary resuscitation with augmented negative intrathoracic pressure may increase the 1-year survival of patients who experience out-of-hospital cardiac arrest, US study findings suggest.

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Medical News

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• Acetaminophen link to asthma supported
• Adolescent diastolic BP influences subsequent mortality risk more than systolic BP
• Esophageal eosinophilia frequency underestimated in Barrett’s esophagus
• Adolescent diastolic BP influences subsequent mortality risk more than systolic BP
• DHA levels in pregnancy linked to schizophrenia risk in offspring
• One in five mood disorder patients suffer self-stigma
• Gender-specific risks for psychosis inheritance identified
• Systolic BP below 140 mmHg benefits uncomplicated hypertensives
• Seasonality linked to premenstrual symptoms in bipolar disorder
• Cortisol awakening response linked to cognition in first-episode psychosis
• Adherence therapy improves BP control in hypertensives
• Cardiac resynchronization therapy beneficial in heart failure
• <i>FKBP5</i> gene variant linked to mood disorders
• Deep TMS may reduce auditory hallucinations in schizophrenia
• Bipolar patients at high risk for the metabolic syndrome

Acetaminophen link to asthma supported Posted: 27 Feb 2011 04:00 PM PST Results from a US study support an association between acetaminophen use and an increased risk for asthma symptoms.

Adolescent diastolic BP influences subsequent mortality risk more than systolic BP Posted: 27 Feb 2011 04:00 PM PST Swedish researchers report that diastolic blood pressure during late adolescence correlates more strongly with subsequent long-term all-cause mortality risk than systolic blood pressure.

Esophageal eosinophilia frequency underestimated in Barrett’s esophagus Posted: 27 Feb 2011 04:00 PM PST Esophageal eosinophilic infiltration extensive enough to constitute esophageal eosinophilia occurs more commonly in Barrett's esophagus than previously believed, study findings suggest.

Adolescent diastolic BP influences subsequent mortality risk more than systolic BP Posted: 27 Feb 2011 04:00 PM PST Swedish researchers report that diastolic blood pressure during late adolescence correlates more strongly with subsequent long-term all-cause mortality risk than systolic blood pressure.

DHA levels in pregnancy linked to schizophrenia risk in offspring Posted: 24 Feb 2011 04:00 PM PST Individuals born to mothers with elevated docosahexaenoic acid levels during pregnancy are at increased risk for developing schizophrenia spectrum disorders, research suggests.

One in five mood disorder patients suffer self-stigma Posted: 24 Feb 2011 04:00 PM PST Results from a European study suggest that around a fifth of patients with bipolar disorder or depression suffer from self-stigma.

Gender-specific risks for psychosis inheritance identified Posted: 23 Feb 2011 04:00 PM PST The daughters of fathers with psychosis are more likely to develop the condition than sons, while the sons of affected mothers are at greater risk than daughters, research suggests.

Systolic BP below 140 mmHg benefits uncomplicated hypertensives Posted: 23 Feb 2011 04:00 PM PST Results from the FEVER study indicate that a target systolic blood pressure of less than 140 mmHg, as recommended by the European Society of Cardiology, improves the outcomes of all hypertensive patients, including those with a very low risk for adverse cardiovascular events.

Seasonality linked to premenstrual symptoms in bipolar disorder Posted: 23 Feb 2011 04:00 PM PST Seasonality is significantly associated with premenstrual syndrome in women with bipolar disorder, particularly those with bipolar II disorder, researchers report.

Cortisol awakening response linked to cognition in first-episode psychosis Posted: 22 Feb 2011 04:00 PM PST Blunted cortisol awakening response is associated with impaired verbal memory and processing speed in patients with first-episode psychosis, researchers have found.

Adherence therapy improves BP control in hypertensives Posted: 22 Feb 2011 04:00 PM PST A course of adherence therapy may improve blood pressure control in hypertensive patients who are noncompliant with antihypertensive medication, findings from a UK study indicate.

Cardiac resynchronization therapy beneficial in heart failure Posted: 22 Feb 2011 04:00 PM PST Cardiac resynchronization therapy improves symptoms, exercise capacity, and quality of life when added to optimal pharmacological therapy in patients with moderate-to-severe heart failure and a normal QRS complex, study results suggest.

<i>FKBP5</i> gene variant linked to mood disorders Posted: 22 Feb 2011 04:00 PM PST A single nucleotide polymorphism in the FK506 binding protein 5 gene is significantly associated with an increased risk for mood disorders, results from a review and meta-analysis of published studies show.

Deep TMS may reduce auditory hallucinations in schizophrenia Posted: 21 Feb 2011 04:00 PM PST Results from a small, preliminary Israeli study suggest that deep transcranial magnetic stimulation may help reduce chronic auditory hallucinations in patients with schizophrenia.

Bipolar patients at high risk for the metabolic syndrome Posted: 21 Feb 2011 04:00 PM PST Bipolar disorder patients have a high prevalence of the metabolic syndrome, say Italian researchers who suggest that such patients should undergo regular risk factor assessments.

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Medical News

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• Novel HIT treatment approach proposed
• Long-term prognosis poor after SVD stroke
• Start dose for UV-B psoriasis treatment important for tolerance, not efficacy
• Educational intervention improves SCC detection in kidney transplant recipients
• Cannabis ingredient could help cancer patients eat again
• Patients with high CV risk need ‘more aggressive treatment’
• Novel variable aids CVD risk identification
• Long-term prognosis poor after SVD stroke
• ESRD risk in Type 1 diabetes remains high despite increased treatment
• High blood glucose predicts in-hospital mortality in elderly nondiabetics
• Air pollution may raise MI risk
• A drink a day may keep the cardiologist away

Novel HIT treatment approach proposed Posted: 24 Feb 2011 04:00 PM PST US researchers have developed a novel selective tyrosine kinase inhibitor that prevents both heparin-induced thrombocytopenia antibody-mediated platelet activation in vitro, and thrombocytopenia and thrombosis in vivo.

Long-term prognosis poor after SVD stroke Posted: 24 Feb 2011 04:00 PM PST Stroke patients with small-vessel disease have worse survival rates than those with other stroke etiologies, shows a long-term study.

Start dose for UV-B psoriasis treatment important for tolerance, not efficacy Posted: 24 Feb 2011 04:00 PM PST Determining the appropriate dose of narrowband ultraviolet-B treatment for psoriasis patients by first working out their minimal erythemal dose does not affect treatment efficacy, but is important for identifying adverse effects, say researchers.

Educational intervention improves SCC detection in kidney transplant recipients Posted: 24 Feb 2011 04:00 PM PST An educational intervention to increase awareness about squamous cell carcinoma (SCC) effectively increases skin self-examination and dermatologist follow-up of suspect lesions in kidney transplant recipients, say researchers.

Cannabis ingredient could help cancer patients eat again Posted: 24 Feb 2011 04:00 PM PST Advanced cancer patients with a poor appetite and chemosensory alterations could have their symptoms improved by treatment with delta-9-tetrahydrocannabinol, an ingredient of cannabis, show study findings.

Patients with high CV risk need ‘more aggressive treatment’ Posted: 24 Feb 2011 04:00 PM PST National Cholesterol Education Program Adult Treatment Panel-III guidelines for non high-density lipoprotein cholesterol may fail to optimize cardiovascular risk reduction among high- and intermediate-risk patients, say researchers.

Novel variable aids CVD risk identification Posted: 24 Feb 2011 04:00 PM PST Spanish researchers have proposed an alternative to the metabolic syndrome for detecting individuals at risk for cardiovascular disease and Type 2 diabetes.

Long-term prognosis poor after SVD stroke Posted: 24 Feb 2011 04:00 PM PST Stroke patients with small-vessel disease have worse survival rates than those with other stroke etiologies, shows a long-term study.

ESRD risk in Type 1 diabetes remains high despite increased treatment Posted: 24 Feb 2011 04:00 PM PST Patients with Type 1 diabetes and macroalbuminuria remain at high risk for end stage renal disease despite significant improvements in treatment and renoprotection over the last 2 decades, say US researchers.

High blood glucose predicts in-hospital mortality in elderly nondiabetics Posted: 24 Feb 2011 04:00 PM PST Having a high serum glucose level on admission to hospital is a significant predictor of in-hospital mortality in nondiabetic elderly patients, suggest study results.

Air pollution may raise MI risk Posted: 24 Feb 2011 04:00 PM PST Researchers report that exposure to air pollution may raise an individual's risk for myocardial infarction by a size similar to that associated with established risk factors, such as physical exertion and coffee consumption.

A drink a day may keep the cardiologist away Posted: 24 Feb 2011 04:00 PM PST Findings from two meta-analyses suggest that individuals who consume one alcoholic drink a day may have a lower risk for heart disease than teetotallers.

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iPhone Medical News

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PracticeFusion Now Available on iPad, Android Tablets Posted: 24 Feb 2011 11:04 AM PST Practice Fusion is now offering iPad and Android tablet access to its free online EMR via the popular LogMeIn Ignition app. The $30 app is designed to allow remote access to other computers and Practice Fusion teamed with LogMeIn to make it available for their EMR. With a free Practice Fusion EMR account and a $29.95 LogMeIn Ignition for iPhone/iPad app, medical providers can use an iPad to chart anywhere they have cell or WiFi reception. Practice Fusion's iPad solution is available at a fraction of the cost of other systems. LogMeIn can also be used to connect Android tablets and smartphones to Practice Fusion using the LogmeIn Ignition for Android app. iPad availability has been a top-requested feature from the Practice Fusion community. Practice Fusion currently has 70,000 users serving 8 million patients. Over 100 million devices worldwide have connected to a LogMeIn service. Both LogMeIn and Practice Fusion provide free support to users. Announcement: Practice Fusion Launches iPad Access at HIMSS ... Link: LogMeIn...

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