Medical News

---

• Significant symptom variability in patients with stable, severe COPD
• Early treatment reduces risk for second psychotic episode
• Childhood adversity linked to mood disorder chronicity
• Patient barriers to mammogram screening remain
• CAC testing improves CV risk prediction, but there are too few events to justify it
• Inhibition of p38 MAPK improves vasodilation in hypercholesterolemic patients
• Genetic predisposition to obesity increases risk for Type 2 diabetes
• Greater hand-grip strength linked to reduced 10-year diabetes risk
• PPI-clopidogrel safety ‘may be unaffected by <i>CYP2C19</i> genotype’
• Super Bowl impact on mortality varies by age, gender

Significant symptom variability in patients with stable, severe COPD Posted: 02 Feb 2011 04:00 PM PST Patients with severe chronic obstructive pulmonary disease report significant daily and weekly symptom variability even during so-called periods of stability, research shows.

Early treatment reduces risk for second psychotic episode Posted: 02 Feb 2011 04:00 PM PST Early treatment is associated with a significantly reduced risk for further psychotic episodes in first-episode psychosis patients, research shows.

Childhood adversity linked to mood disorder chronicity Posted: 02 Feb 2011 04:00 PM PST Exposure to family problems in childhood is associated with an increased risk for mood disorder chronicity in adulthood, study results show.

Patient barriers to mammogram screening remain Posted: 01 Feb 2011 04:00 PM PST Some groups of women are still avoiding mammograms despite having health insurance and receiving regular reminders, US study data show.

CAC testing improves CV risk prediction, but there are too few events to justify it Posted: 01 Feb 2011 04:00 PM PST Study findings suggest that coronary artery calcium scores improve cardiovascular risk prediction in patients without indication for statin therapy, but that the low numbers of patients ultimately reclassified to a high-risk category, and low overall CV event rates do not justify CAC testing in these individuals.

Inhibition of p38 MAPK improves vasodilation in hypercholesterolemic patients Posted: 01 Feb 2011 04:00 PM PST Inhibition of p38 mitogen-activated protein kinase, a mediator of vascular inflammation, improves nitric oxide-mediated vasodilation and reduces inflammation in hypercholesterolemic patients, say researchers.

Genetic predisposition to obesity increases risk for Type 2 diabetes Posted: 01 Feb 2011 04:00 PM PST Carriers of the obesity–associated allele of 12 single nucleotide polymorphisms previously linked to variation in body mass index are at increased risk for Type 2 diabetes, suggest study findings.

Greater hand-grip strength linked to reduced 10-year diabetes risk Posted: 01 Feb 2011 04:00 PM PST Greater hand-grip strength in middle age is associated with a significantly reduced 10-year risk for Type 2 diabetes in lean individuals, show results from a US study.

PPI-clopidogrel safety ‘may be unaffected by <i>CYP2C19</i> genotype’ Posted: 01 Feb 2011 04:00 PM PST Co-administration of a proton pump inhibitor and clopidogrel does not appear to be associated with an increased risk for cardiovascular events or death, irrespective of the patient's cytochrome P450 C219 genotype, research suggests.

Super Bowl impact on mortality varies by age, gender Posted: 01 Feb 2011 04:00 PM PST The Los Angeles Rams' Super Bowl loss of 1980 triggered increased deaths in both men and women and especially in older patients, a study of the American Football team's supporters has found.

You are subscribed to email updates from MedWire Medical News Combined Feed To stop receiving these emails, you may unsubscribe now.	Email delivery powered by Google
Google Inc., 20 West Kinzie, Chicago IL USA 60610