Medical News

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• <i>MBL2</i> gene variant linked to recurrent infective COPD exacerbations
• Excessive cannabis use linked to early-onset BD
• Neural response to verbal task may help diagnose schizophrenia
• Functional dyspepsia patients have excessive small-bowel-homing T lymphocytes
• VTE prevalence increasing in USA
• CABG-linked stroke in decline
• UROD enzyme could reduce toxic effects of RT for head and neck patients
• Benefit of statins is comparable, irrespective of CRP levels
• Combination therapy effective for treating mixed dyslipidemia in women
• High CRP level linked to prediabetes
• Diagnostic accuracy of HbA1c differs with age
• Trimetazidine shows therapeutic benefits in HF patients
• New data reveal risks, consequences of Fidelis ICD lead failure
• CABG-linked stroke in decline

<i>MBL2</i> gene variant linked to recurrent infective COPD exacerbations Posted: 01 Feb 2011 04:00 PM PST Patients with chronic obstructive pulmonary disease who carry variants of the mannose-binding lectin gene that result in a deficiency of the protein, are at increased risk for recurrent infective exacerbations, study results show.

Excessive cannabis use linked to early-onset BD Posted: 01 Feb 2011 04:00 PM PST Patients with bipolar disorder who have a history of excessive cannabis use are more likely to have developed the mood disorder at a younger age than those without such a history, researchers have found.

Neural response to verbal task may help diagnose schizophrenia Posted: 01 Feb 2011 04:00 PM PST Schizophrenia patients and those with bipolar disorder show differential neural response patterns to a verbal fluency task, with the differences being highly diagnostic for schizophrenia, researchers report.

Functional dyspepsia patients have excessive small-bowel-homing T lymphocytes Posted: 01 Feb 2011 04:00 PM PST Individuals with functional dyspepsia have significantly increased concentrations of small-bowel-homing T lymphocyte cells and cytokines compared with healthy controls, say researchers.

VTE prevalence increasing in USA Posted: 31 Jan 2011 04:00 PM PST The prevalence of venous thromboembolism has increased rapidly in the USA in recent years and will continue to do so for the foreseeable future, placing pressure on the US healthcare system, study findings indicate.

CABG-linked stroke in decline Posted: 31 Jan 2011 04:00 PM PST Patients' risk for suffering stroke during or after coronary artery bypass grafting has fallen over recent years, despite a worsening risk profile among candidates for the operation, shows research published in JAMA.

UROD enzyme could reduce toxic effects of RT for head and neck patients Posted: 31 Jan 2011 04:00 PM PST The "disappointing levels" of toxic effects experienced by head and neck cancer patients treated with radiation therapy could be reduced by targeting the enzyme uroporphyrinogen decarboxylase, report researchers.

Benefit of statins is comparable, irrespective of CRP levels Posted: 31 Jan 2011 04:00 PM PST UK researchers report that baseline levels of C-reactive protein do not alter the beneficial effects of statin therapy.

Combination therapy effective for treating mixed dyslipidemia in women Posted: 31 Jan 2011 04:00 PM PST Study findings suggest that a combination of fibrate and statin therapies should be considered as a treatment option for women with mixed dyslipidemia.

High CRP level linked to prediabetes Posted: 31 Jan 2011 04:00 PM PST Study results show that having an elevated level of high-sensitivity C-reactive protein, a known marker of inflammation, is associated with the presence of prediabetes.

Diagnostic accuracy of HbA1c differs with age Posted: 31 Jan 2011 04:00 PM PST The sensitivity and specificity of glycated hemoglobin cut-points for the diagnosis of diabetes decrease with age, say researchers who point out that this may lead to a reduction in diagnostic accuracy in older individuals.

Trimetazidine shows therapeutic benefits in HF patients Posted: 31 Jan 2011 04:00 PM PST Trimetazidine, a piperazine derivative used as an anti-anginal agent, may be useful in the treatment of patients with heart failure, a meta-analysis suggests.

New data reveal risks, consequences of Fidelis ICD lead failure Posted: 31 Jan 2011 04:00 PM PST The failure of Medtronic Spring Fidelis implantable cardioverter-defibrillator leads is reviewed in depth in the journal Circulation this month, with important implications for the clinical management of patients with the device.

CABG-linked stroke in decline Posted: 31 Jan 2011 04:00 PM PST Patients' risk for suffering stroke during or after coronary artery bypass grafting has fallen over recent years, despite a worsening risk profile among candidates for the operation, shows research published in JAMA.

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