Medical News

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• <i>CYP2C19</i> variants do not influence clopidogrel efficacy
• Poor outcomes after dissection unrelated to thrombolysis
• Gray matter loss due to substance use ‘not increased in ARMS patients’
• ‘Mixicity should be extended beyond bipolar I disorder’
• Possible link between psoriasis and CVD risk factors
• Growth hormone linked to CVD risk in obese individuals
• Genetic study indicates ‘unsuspected’ mechanisms, therapeutic targets for CHD
• Screening strategy ‘cost-effective’ for the Lynch syndrome
• Genetic study indicates ‘unsuspected’ mechanisms, therapeutic targets for CHD
• Obesity predicts gastroparesis in patients with diabetic neuropathy
• Elevated resistin in diabetes linked to renal complications
• Smoking increases CHD risk more in women than in men
• CAD detection by angiography ‘varies considerably’ across hospitals
• <i>CYP2C19</i> variants do not influence clopidogrel efficacy
• Tamoxifen benefit is long lasting
• Mind/body psychological skills intervention could improve IVF outcomes

<i>CYP2C19</i> variants do not influence clopidogrel efficacy Posted: 11 Aug 2011 05:00 PM PDT Polymorphisms in the cytochrome P450 2C19 gene do not influence the clinical efficacy of clopidogrel, results of a systematic review and meta-analysis show.

Poor outcomes after dissection unrelated to thrombolysis Posted: 11 Aug 2011 05:00 PM PDT A large study shows that the poor outcomes seen after thrombolysis in patients with stroke caused by arterial dissection are not a treatment effect.

Gray matter loss due to substance use ‘not increased in ARMS patients’ Posted: 11 Aug 2011 05:00 PM PDT Individuals in an at-risk mental state for psychosis do not show greater levels of gray matter loss associated with substance use than mentally healthy individuals, show UK study results.

‘Mixicity should be extended beyond bipolar I disorder’ Posted: 11 Aug 2011 05:00 PM PDT Bipolar I disorder patients with a lifetime history of exclusively mixed, but not manic, episodes are at increased risk for suicide and have higher comorbidity rates than other patients with the condition, study results show.

Possible link between psoriasis and CVD risk factors Posted: 11 Aug 2011 05:00 PM PDT Patients with psoriasis are more likely than those with dermatitis to develop risk factors for cardiovascular disease, report researchers.

Growth hormone linked to CVD risk in obese individuals Posted: 11 Aug 2011 05:00 PM PDT Growth hormone secretion in obese individuals may be associated with cardiovascular disease risk, study findings suggest.

Genetic study indicates ‘unsuspected’ mechanisms, therapeutic targets for CHD Posted: 11 Aug 2011 05:00 PM PDT Study results show that there are several overlapping associations between coronary heart disease -associated single nucleotide polymorphisms and established and emerging cardiovascular risk factors.

Screening strategy ‘cost-effective’ for the Lynch syndrome Posted: 11 Aug 2011 05:00 PM PDT All patients newly diagnosed with colon cancer should be screened for the Lynch syndrome, an inherited defect that underlies around 3–5% of such cancers, US researchers believe.

Genetic study indicates ‘unsuspected’ mechanisms, therapeutic targets for CHD Posted: 11 Aug 2011 05:00 PM PDT Study results show that there are several overlapping associations between coronary heart disease -associated single nucleotide polymorphisms and established and emerging cardiovascular risk factors.

Obesity predicts gastroparesis in patients with diabetic neuropathy Posted: 11 Aug 2011 05:00 PM PDT Obesity is an independent predictor of gastroparesis in patients with Type 2 diabetes and neuropathy, a nested case–control study shows.

Elevated resistin in diabetes linked to renal complications Posted: 11 Aug 2011 05:00 PM PDT Patients with Type 2 diabetes who develop the common complications of renal dysfunction, hypertension, and gout exhibit elevated levels of the adipose protein resistin, study results show.

Smoking increases CHD risk more in women than in men Posted: 11 Aug 2011 05:00 PM PDT Women who smoke have a 25% higher risk for developing coronary heart disease than men who smoke, report US researchers.

CAD detection by angiography ‘varies considerably’ across hospitals Posted: 11 Aug 2011 05:00 PM PDT The detection rate of obstructive coronary artery disease at elective coronary angiography varies widely among hospitals, report US researchers.

<i>CYP2C19</i> variants do not influence clopidogrel efficacy Posted: 11 Aug 2011 05:00 PM PDT Polymorphisms in the cytochrome P450 2C19 gene do not influence the clinical efficacy of clopidogrel, results of a systematic review and meta-analysis show.

Tamoxifen benefit is long lasting Posted: 07 Aug 2011 05:00 PM PDT The survival benefit from 5 years of treatment with tamoxifen lasts at least 15 years in women treated for early breast cancer, US researchers report.

Mind/body psychological skills intervention could improve IVF outcomes Posted: 01 May 2011 05:00 PM PDT US study results suggest that psychological distress may be detrimental to IVF outcomes.

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