Medical News

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• Prior psychiatric hospitalization increases risk for CV mortality
• Diabetes patients vulnerable to medication errors in care homes
• Algal oil reduces triglycerides, increases HDL, LDL cholesterol
• Socioeconomic status explains racial disparities in diet, exercise, weight
• HIV infection linked to increased cancer risk
• Medical comorbidities common in BD patients
• Prior psychiatric hospitalization increases risk for CV mortality
• Outcomes mostly favorable for ‘too good to treat’ stroke patients
• NICE Fast-tracks Apixaban for postsurgery VTE prevention
• Real-time glucose monitoring offers long-term benefits
• Graphic, numeric tools equal in communicating HbA1c results

Prior psychiatric hospitalization increases risk for CV mortality Posted: 30 Nov 2011 04:00 PM PST Patients with noncardiac chest pain who have previously been hospitalized for a psychiatric condition have an increased risk for cardiovascular mortality, researchers suggest.

Diabetes patients vulnerable to medication errors in care homes Posted: 30 Nov 2011 04:00 PM PST Care home residents who have diabetes are at risk for adverse events resulting from mismanagement of their medication, show study findings.

Algal oil reduces triglycerides, increases HDL, LDL cholesterol Posted: 30 Nov 2011 04:00 PM PST Docosahexaenoic acid supplementation from algal oil reduces serum triglycerides and increases high-density lipoprotein and low-density lipoprotein cholesterol in individuals free from coronary heart disease, US research shows.

Socioeconomic status explains racial disparities in diet, exercise, weight Posted: 30 Nov 2011 04:00 PM PST Few of the racial/ethnic differences observed in diet, exercise, and weight status among US adults are explained by nutrition- and health-related psychosocial factors, report researchers.

HIV infection linked to increased cancer risk Posted: 30 Nov 2011 04:00 PM PST People infected with HIV have an increased risk for several cancers compared with those without the infection, report researchers.

Medical comorbidities common in BD patients Posted: 30 Nov 2011 04:00 PM PST Medical comorbidities affect more than half of patients with bipolar disorder and are significantly associated with an increased number of previous mood episodes, early age at onset, smoking, anxiety, and substance use disorders, researchers report.

Prior psychiatric hospitalization increases risk for CV mortality Posted: 30 Nov 2011 04:00 PM PST Patients with noncardiac chest pain who have previously been hospitalized for a psychiatric condition have an increased risk for cardiovascular mortality, research suggests.

Outcomes mostly favorable for ‘too good to treat’ stroke patients Posted: 30 Nov 2011 04:00 PM PST Most stroke patients considered "too good to treat" with tissue plasminogen activator have good outcomes, say researchers.

NICE Fast-tracks Apixaban for postsurgery VTE prevention Posted: 30 Nov 2011 04:00 PM PST The UK National Institute for Health and Clinical Excellence has published final draft guidance recommending apixaban for the prevention of venous thromboembolism in adults who have undergone planned total hip or knee replacement surgery.

Real-time glucose monitoring offers long-term benefits Posted: 29 Nov 2011 04:00 PM PST Real-time continuous glucose monitoring has long-term glycemic-lowering effects in patients with Type 2 diabetes who are not on prandial insulin, report researchers.

Graphic, numeric tools equal in communicating HbA1c results Posted: 29 Nov 2011 04:00 PM PST Using a color-coded recording tool to communicate glycated hemoglobin results to patients with diabetes is no more effective at improving HbA1c levels than using a numeric tool, report researchers.

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Medical News

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• Nurse/health worker-led intervention improves CVD risk profile
• ‘DIDO’ time rarely meets recommended limit
• Fatty acid supplementation reduces ventricular arrhythmia-related events
• Fatty acid supplementation reduces ventricular arrhythmia-related events
• Elevated adiponectin decreases PAD risk in women
• BD, schizophrenia patients show altered neurotransmitter transporter expression
• Six rare CNVs strongly linked to schizophrenia
• Full prescription coverage improves adherence, reduces adverse outcomes, spending
• One in ten PCI patients readmitted within 30 days
• Dalcetrapib raises HDL cholesterol in diabetes, the metabolic syndrome
• Urinary F₂-isoprostanes may predict diabetes risk
• Ezetimibe reduces atherogenic small, dense LDL cholesterol
• Dietary fiber link to diverticulosis risk refuted
• sVAP-1 identified as a cardiovascular risk factor
• Ezetimibe reduces atherogenic small, dense LDL cholesterol
• Comorbid migraine linked to poorer outcomes in BD patients
• Regional thalamic volume deficits identified in early-onset psychosis
• Urgent-access TIA clinics beat hospitalization for cost effectiveness
• IV iron may reduce thromboembolism risk in chemotherapy patients

Nurse/health worker-led intervention improves CVD risk profile Posted: 29 Nov 2011 04:00 PM PST An intervention delivered by a nurse practitioner/community health worker team improves the risk profile of cardiovascular disease patients more than an enhanced usual care program does, researchers say.

‘DIDO’ time rarely meets recommended limit Posted: 29 Nov 2011 04:00 PM PST The door-in to door-out time for patients being transferred to another hospital for percutaneous coronary intervention in the USA rarely meets the recommended 30 minutes, researchers say.

Fatty acid supplementation reduces ventricular arrhythmia-related events Posted: 29 Nov 2011 04:00 PM PST Low doses of n-3 fatty acids reduce the risk for ventricular arrhythmia-related events in post-myocardial infarction patients with diabetes, research shows.

Fatty acid supplementation reduces ventricular arrhythmia-related events Posted: 29 Nov 2011 04:00 PM PST Low doses of n-3 fatty acids reduce the risk for ventricular arrhythmia-related events in post-myocardial infarction patients with diabetes, research shows.

Elevated adiponectin decreases PAD risk in women Posted: 29 Nov 2011 04:00 PM PST Women with elevated adiponectin levels may be at a decreased risk for peripheral artery disease, study findings indicate.

BD, schizophrenia patients show altered neurotransmitter transporter expression Posted: 29 Nov 2011 04:00 PM PST Results from a postmortem study show that individuals with bipolar disorder and schizophrenia have significantly altered expression of glutamate and dopamine transporters in the frontal cortex compared with mentally healthy individuals.

Six rare CNVs strongly linked to schizophrenia Posted: 29 Nov 2011 04:00 PM PST Results from a UK study provide strong support for an association between schizophrenia and six rare copy number variants.

Full prescription coverage improves adherence, reduces adverse outcomes, spending Posted: 28 Nov 2011 04:00 PM PST A full prescription coverage medical insurance plan after myocardial infarction improves medication adherence, decreases risk for vascular events, and reduces patient spending without increasing overall health costs, an analysis suggests.

One in ten PCI patients readmitted within 30 days Posted: 28 Nov 2011 04:00 PM PST Nearly one in ten patients who undergo percutaneous coronary intervention are readmitted within 30 days, a study has found.

Dalcetrapib raises HDL cholesterol in diabetes, the metabolic syndrome Posted: 28 Nov 2011 04:00 PM PST Dalcetrapib is effective at raising high-density lipoprotein cholesterol among patients with Type 2 diabetes and/or the metabolic syndrome who are at significant risk for cardiovascular events, report researchers.

Urinary F<sub>2</sub>-isoprostanes may predict diabetes risk Posted: 28 Nov 2011 04:00 PM PST Urinary F2-isoprostanes may be useful for identifying individuals at high risk for Type 2 diabetes, suggest study findings.

Ezetimibe reduces atherogenic small, dense LDL cholesterol Posted: 28 Nov 2011 04:00 PM PST Treatment with ezetimibe alone or in combination with simvastatin lowers the concentration of small, dense low-density lipoprotein cholesterol particles in patients with Type 2 diabetes, research shows.

Dietary fiber link to diverticulosis risk refuted Posted: 28 Nov 2011 04:00 PM PST Research published in the journal Gastroenterology challenges the belief that a high-fiber diet protects against the development of diverticulosis.

sVAP-1 identified as a cardiovascular risk factor Posted: 28 Nov 2011 04:00 PM PST Soluble vascular adhesion protein-1 activity correlates with cardiovascular risk factors and early atherosclerotic manifestations, report researchers.

Ezetimibe reduces atherogenic small, dense LDL cholesterol Posted: 28 Nov 2011 04:00 PM PST Treatment with ezetimibe alone or in combination with simvastatin lowers the concentration of small, dense low-density lipoprotein cholesterol particles in patients with Type 2 diabetes, research shows.

Comorbid migraine linked to poorer outcomes in BD patients Posted: 28 Nov 2011 04:00 PM PST Patients with bipolar disorder who also suffer from migraine have poorer outcomes than those who do not experience such headaches, results from a Brazilian study suggest.

Regional thalamic volume deficits identified in early-onset psychosis Posted: 28 Nov 2011 04:00 PM PST Results from a Spanish study of adolescents with early-onset psychosis show that thalamic volume deficits are most pronounced in the right anterior mediodorsal and posterior pulvinar regions.

Urgent-access TIA clinics beat hospitalization for cost effectiveness Posted: 28 Nov 2011 04:00 PM PST Widespread availability of urgent-access transient ischemic attack clinics avoids the need for hospitalization, which benefits only a very small proportion of patients, show the findings of a decision analysis.

IV iron may reduce thromboembolism risk in chemotherapy patients Posted: 28 Nov 2011 04:00 PM PST Administering intravenous iron may reduce the risk for venous thromboembolism in patients with chemotherapy induced anemia, US study findings suggest.

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Medical News

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• Diabetes underreported in hospital admission data
• VerifyNow P2Y12 assay influenced by <i>CYP2C9</i> variants
• High CHADS₂ also predicts bleeding, mortality

Diabetes underreported in hospital admission data Posted: 27 Nov 2011 04:00 PM PST Hospital admission data do not accurately estimate the number of admissions, bed stays, and length of stay for individuals with diabetes, report UK researchers.

VerifyNow P2Y12 assay influenced by <i>CYP2C9</i> variants Posted: 14 Nov 2011 04:00 PM PST Loss-of-function variants in cytochrome P450 2C9 are associated with decreased clopidogrel-mediated platelet inhibition and an increased rate of high on-treatment residual platelet reactivity by the VerifyNow P2Y12 assay, Austrian researchers report.

High CHADS<sub>2</sub> also predicts bleeding, mortality Posted: 14 Nov 2011 04:00 PM PST The CHADS2 score predicts the risk for bleeding, intracranial bleeding, and mortality, as well as stroke, in patients with atrial fibrillation, shows an analysis of the RE-LY trial.

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Medical News

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• Medical history, physical examination identify HF in primary care
• BP control ‘inadequate’ in most Japanese chronic kidney disease patients
• Burden of treatment inadequately addressed for diabetes care
• Burden of treatment not adequately addressed during diabetes care visits
• Medical history, physical examination identify HF in primary care
• BP control ‘inadequate’ in most Japanese chronic kidney disease patients
• Osteoprotegerin better marker of atherosclerosis than hsCRP, traditional risk factors
• Two weight-loss interventions ‘effective’ in clinical practice
• NICE releases updated guidelines on cesarean section
• FDA revokes approval for bevacizumab in breast cancer
• Inhaler technique training by pharmacists improved asthma control
• Recent TIA may not influence thrombolysis outcomes
• Autoimmune disease linked to increased pulmonary embolism risk
• Teens with BD show distinct patterns of poor sleep quality
• Olfactory bulb volume reduced in schizophrenia patients
• Bipolar disorder not linked to increased age-related declines in cognition
• Review supports infection link to schizophrenia
• Harm avoidance and self-directedness traits linked to BD vulnerability
• CDSS ‘most effective tool’ for assessing depressive symptoms in schizophrenia
• Lithium therapy may lower suicide risk in bipolar depression
• Extra screening beneficial if alcohol dependency co-occurs with schizophrenia
• Apixaban no more effective than enoxaparin in preventing VTE

Medical history, physical examination identify HF in primary care Posted: 27 Nov 2011 04:00 PM PST Medical history and physical examination are major sources of diagnostic information when identifying primary care patients at risk for HF, researchers suggest.

BP control ‘inadequate’ in most Japanese chronic kidney disease patients Posted: 27 Nov 2011 04:00 PM PST Blood pressure control is inadequate in the majority of Japanese chronic kidney disease patients, an analysis shows.

Burden of treatment inadequately addressed for diabetes care Posted: 27 Nov 2011 04:00 PM PST Study findings show that although patients with diabetes routinely discuss burden of treatment during clinic visits, many do not have their concerns addressed at the time.

Burden of treatment not adequately addressed during diabetes care visits Posted: 27 Nov 2011 04:00 PM PST Study findings show that although patients with diabetes routinely discuss burden of treatment during clinic visits, many do not have their concerns addressed at the time.

Medical history, physical examination identify HF in primary care Posted: 27 Nov 2011 04:00 PM PST Medical history and physical examination are major sources of diagnostic information when identifying primary care patients at risk for HF, researchers suggest.

BP control ‘inadequate’ in most Japanese chronic kidney disease patients Posted: 27 Nov 2011 04:00 PM PST Blood pressure control is inadequate in the majority of Japanese chronic kidney disease patients, an analysis shows.

Osteoprotegerin better marker of atherosclerosis than hsCRP, traditional risk factors Posted: 27 Nov 2011 04:00 PM PST Danish researchers say that osteoprotegerin, a glycoprotein that binds to the receptor activator for nuclear factor κB ligand, may be a promising biomarker of atherosclerosis.

Two weight-loss interventions ‘effective’ in clinical practice Posted: 27 Nov 2011 04:00 PM PST Results of a study published in The New England Journal of Medicine show that clinically significant weight loss can be achieved and sustained in obese individuals over 24 months by two separate behavioral interventions.

NICE releases updated guidelines on cesarean section Posted: 27 Nov 2011 04:00 PM PST The UK's National Institute for Health and Clinical Excellence has released updated guidelines on cesarean section.

FDA revokes approval for bevacizumab in breast cancer Posted: 27 Nov 2011 04:00 PM PST The US Food and Drug Administration has announced that it is revoking its approval for the use of bevacizumab in women with breast cancer.

Inhaler technique training by pharmacists improved asthma control Posted: 27 Nov 2011 04:00 PM PST Results from a French study show that inhaler technique training by pharmacists is feasible and improves asthma control in patients with the respiratory condition.

Recent TIA may not influence thrombolysis outcomes Posted: 27 Nov 2011 04:00 PM PST Having had a recent transient ischemic attack is unlikely to affect the outcomes of patients undergoing thrombolysis for acute stroke, a study suggests.

Autoimmune disease linked to increased pulmonary embolism risk Posted: 27 Nov 2011 04:00 PM PST People admitted to hospital with an autoimmune disorder have a high risk for pulmonary embolism in the year after admission, Swedish study data show.

Teens with BD show distinct patterns of poor sleep quality Posted: 24 Nov 2011 04:00 PM PST Adolescents with bipolar disorder have distinct patterns of poor sleep quality, with longer sleep onset latency and an increased number of nighttime awakenings compared with their mentally healthy counterparts, study results show.

Olfactory bulb volume reduced in schizophrenia patients Posted: 24 Nov 2011 04:00 PM PST Results from a US study show that olfactory bulb volume is reduced in patients with schizophrenia, supporting previous reports of abnormal olfactory function in patients with the mental health disorder.

Bipolar disorder not linked to increased age-related declines in cognition Posted: 23 Nov 2011 04:00 PM PST Results from a Swiss study of elderly patients with bipolar disorder suggest that they do not have greater age-related declines in cognition compared with their mentally healthy counterparts.

Review supports infection link to schizophrenia Posted: 23 Nov 2011 04:00 PM PST Results from a systematic review and meta-analysis of published studies support an association between certain infections and schizophrenia.

Harm avoidance and self-directedness traits linked to BD vulnerability Posted: 22 Nov 2011 04:00 PM PST Results from a Brazilian study suggest that harm avoidance temperament trait and the self-directedness character trait are associated with increased vulnerability to bipolar disorder.

CDSS ‘most effective tool’ for assessing depressive symptoms in schizophrenia Posted: 22 Nov 2011 04:00 PM PST The Calgary Depression Scale for Schizophrenia is the most reliable and valid tool for assessing depressive symptoms in patients with schizophrenia, researchers report.

Lithium therapy may lower suicide risk in bipolar depression Posted: 21 Nov 2011 04:00 PM PST Study findings indicate that lithium therapy may reduce suicide risk in patients with bipolar depression by increasing cortical gray matter volumes.

Extra screening beneficial if alcohol dependency co-occurs with schizophrenia Posted: 21 Nov 2011 04:00 PM PST US researchers say that individuals with schizophrenia and co-occurring alcohol dependency may report their medical problems less accurately than people with alcohol dependency alone.

Apixaban no more effective than enoxaparin in preventing VTE Posted: 14 Nov 2011 04:00 PM PST An extended course of thromboprophylaxis with apixaban is no more effective in preventing venous thromboembolism in medically ill patients than a shorter course of enoxaparin, suggest the results of the ADOPT trial.

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