Thursday, November 17, 2011

Medical News

Medical News

Quitting smoking for 3 years improves heart disease prognosis

Posted: 17 Nov 2011 04:00 PM PST

Quitting cigarette smoking for at least 3 years is associated with important improvements in exercise parameters that predict cardiovascular disease risk, US research shows.

Triple-dose clopidogrel overcomes resistance in some patients

Posted: 17 Nov 2011 04:00 PM PST

Using a triple dose of clopidogrel may overcome the blunted response to the drug seen in some patients with genetic variants in CYP2C19, a study suggests.

Colchicine reduces complications of cardiac surgery

Posted: 17 Nov 2011 04:00 PM PST

Treatment with colchicine following cardiac surgery reduces the incidence of postoperative atrial fibrillation, results of a COPPS substudy show.

Type 2 diabetes patients at risk for overactive bladder

Posted: 17 Nov 2011 04:00 PM PST

Overactive bladder is common in patients with Type 2 diabetes, affecting almost a quarter of patients, half of whom suffer from active urinary incontinence, report researchers.

Sulodexide fails to prevent renal function decline in Type 2 diabetes

Posted: 17 Nov 2011 04:00 PM PST

Sulodexide is no more effective than placebo for preventing progression to kidney failure in patients with Type 2 diabetes and nephropathy, research shows.

Smoking cessation recommended for BE patients

Posted: 17 Nov 2011 04:00 PM PST

Patients with Barrett's esophagus should be encouraged to give up smoking, recommend researchers who found that tobacco use doubles the risk for progression to esophageal adenocarcinoma.

Evacetrapib raises HDL, lowers LDL cholesterol

Posted: 17 Nov 2011 04:00 PM PST

Treatment with evacetrapib, a cholesteryl ester transfer protein inhibitor, administered as monotherapy or in combination with statins, increases high-density lipoprotein cholesterol levels and decreases low-density lipoprotein cholesterol levels after 12 weeks, US researchers report.

Elevated CRP, HSV-1 exposure linked to reduced cognitive function schizophrenia patients

Posted: 17 Nov 2011 04:00 PM PST

Elevated C-reactive protein levels and exposure to herpes simplex virus type 1 are associated with significantly reduced cognitive function in patients with schizophrenia, research shows.

Denial or blame coping strategies common in prodromal BD patients with psychosis

Posted: 17 Nov 2011 04:00 PM PST

Results from a Korean study show that bipolar disorder patients with psychosis tend to use denial or blame coping strategies and experience attenuated psychotic symptoms more often during the prodromal period than their counterparts without psychosis.

J-shaped curve found for SBP and recurrent stroke

Posted: 17 Nov 2011 04:00 PM PST

Patients with recent stroke may not tolerate low–normal systolic blood pressure levels, indicate results from PRoFESS.

Triple-dose clopidogrel overcomes resistance in some patients

Posted: 17 Nov 2011 04:00 PM PST

Using a triple dose of clopidogrel may overcome the blunted response to the drug seen in some patients with genetic variants in CYP2C19, a study suggests.

Tamoxifen discontinuation rate high in men with breast cancer

Posted: 16 Nov 2011 04:00 PM PST

Approximately one in five men with breast cancer will discontinue treatment with tamoxifen because of intolerable side effects such as venous thromboembolism and loss of libido, US researchers report in the Annals of Oncology.

Dronedarone increases risk for death in permanent AF

Posted: 16 Nov 2011 04:00 PM PST

The Permanent Atrial Fibrillation Outcomes Study Using Dronedarone on Top of Standard Therapy study shows that dronedarone increases rates of heart failure, stroke, and death from cardiovascular causes in patients with permanent atrial fibrillation.

MANTRA-PAF: RF ablation superior to drugs in paroxysmal AF

Posted: 16 Nov 2011 04:00 PM PST

Patients with paroxysmal atrial fibrillation who receive radiofrequency ablation have significantly lower AF burden – but not cumulative AF burden – at 24 months, compared with patients treated with anti-arrhythmic drugs, research shows.

High-dose atorvastatin, rosuvastatin regress plaque to similar degree

Posted: 16 Nov 2011 04:00 PM PST

A head-to-head comparison of the highest doses of atorvastatin and rosuvastatin in the Study of Coronary Atheroma by Intravascular Ultrasound: Effect of Rosuvastatin Versus Atorvastatin showed that the two treatments resulted in significant but similar regression of coronary atherosclerosis.

‘No justification’ for diabetes, previous stroke thrombolysis exclusions

Posted: 16 Nov 2011 04:00 PM PST

Patients with diabetes or a history of stroke benefit from thrombolysis in the event of an acute stroke, shows a collaboration between SITS and VISTA researchers.

High-dose atorvastatin, rosuvastatin regress plaque to similar degree

Posted: 16 Nov 2011 04:00 PM PST

A head-to-head comparison of the highest doses of atorvastatin and rosuvastatin in the Study of Coronary Atheroma by Intravascular Ultrasound: Effect of Rosuvastatin Versus Atorvastatin showed that the two treatments resulted in significant but similar regression of coronary atherosclerosis.

‘No justification’ for diabetes, previous stroke thrombolysis exclusions

Posted: 16 Nov 2011 04:00 PM PST

Patients with diabetes or a history of stroke benefit from thrombolysis in the event of an acute stroke, shows a collaboration between SITS and VISTA researchers.

Decline in breast cancer mortality slowest in elderly women

Posted: 13 Nov 2011 04:00 PM PST

The rate of breast cancer death in the general population and the risk for breast cancer death in newly diagnosed patients is decreasing two to three times faster for younger women than for those aged 75 years and older, US researchers report.
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