Medical News

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• Mortality risk similar for White vs Black diabetics
• Factors linked to occupational disability in BD identified
• DUP may differentiate schizoaffective disorder from BD
• LCZ696 findings of PARAMOUNT importance
• Non-invasive fractional flow reserve still out of reach
• PROTECT: Still no clear winner in the battle of the stent generations
• Obese adolescents have high incidence gallstones
• Gold-standard antibiotic suboptimal for end-stage renal disease
• Obese adolescents have high incidence gallstones
• Model predicts lung cancer risk
• Reduced synaptic-function explains neuronal atrophy in major depressive disorder
• Informed consent process lacks information about adverse events, treatment alternatives
• Knocking some sense into cystic fibrosis assessment
• Model predicts lung cancer risk
• TREVO 2 adds momentum to mechanical intervention for stroke

Mortality risk similar for White vs Black diabetics Posted: 28 Aug 2012 05:00 PM PDT Diabetes does not lead to an intrinsically poorer survival in African Americans than it does in White Americans, report US researchers.

Factors linked to occupational disability in BD identified Posted: 28 Aug 2012 05:00 PM PDT Occupational disability in patients with bipolar disorder is associated with the presence of axis II disorders, a greater number of previous manic episodes, older age, and not being in a stable relationship, researchers report.

DUP may differentiate schizoaffective disorder from BD Posted: 28 Aug 2012 05:00 PM PDT Among individuals with a first episode of psychotic mania (FEPM), a longer duration of untreated psychosis may differentiate patients with schizoaffective disorder from those with bipolar I disorder, study results suggest.

LCZ696 findings of PARAMOUNT importance Posted: 27 Aug 2012 05:00 PM PDT A phase II trial of the first-in-class angiotensin receptor neprilysin inhibitor, LCZ696, has shown that the compound may improve treatment of heart failure patients.

Non-invasive fractional flow reserve still out of reach Posted: 27 Aug 2012 05:00 PM PDT A novel, non-invasive approach to determining fractional flow reserve failed to show sufficient diagnostic accuracy to meet the primary endpoint of the DeFACTO trial, but was more accurate for diagnosing coronary artery ischemia than computed tomography, reported the trial's lead investigator.

PROTECT: Still no clear winner in the battle of the stent generations Posted: 27 Aug 2012 05:00 PM PDT Three-year rates of stent thrombosis with zotarolimus- and sirolimus-eluting stents are low and comparable, show results of the PROTECT trial.

Obese adolescents have high incidence gallstones Posted: 27 Aug 2012 05:00 PM PDT The recent rise in childhood obesity has led to a dramatic increase in the number of older children and adolescents with gallstones, say researchers.

Gold-standard antibiotic suboptimal for end-stage renal disease Posted: 27 Aug 2012 05:00 PM PDT Only one-fifth of patients with end-stage renal disease and methicillin-susceptible Staphylococcus aureus bacteremia are treated with cefazolin, research suggests.

Obese adolescents have high incidence gallstones Posted: 27 Aug 2012 05:00 PM PDT The recent rise in childhood obesity has led to a dramatic increase in the number of older children and adolescents with gallstones, say researchers.

Model predicts lung cancer risk Posted: 27 Aug 2012 05:00 PM PDT Researchers have shown that The Liverpool Lung Project Risk Model is effective in identifying those at the highest risk for lung cancer within 5 years, and who are therefore suitable for computed tomography screening.

Reduced synaptic-function explains neuronal atrophy in major depressive disorder Posted: 27 Aug 2012 05:00 PM PDT Patients with major depressive disorder have lower expression of synaptic-function-related genes in the dorsolateral prefrontal cortex than their counterparts without the condition, indicate findings from a gene profiling study.

Informed consent process lacks information about adverse events, treatment alternatives Posted: 27 Aug 2012 05:00 PM PDT There is a lack of information about adverse events and treatment options during the informed consent process, show the results of a video simulation-based study of patients with schizophrenia, family members of patients with schizophrenia, and healthcare providers.

Knocking some sense into cystic fibrosis assessment Posted: 27 Aug 2012 05:00 PM PDT A deficient sense of smell is significantly more common among individuals with cystic fibrosis than it is in healthy people, report researchers.

Model predicts lung cancer risk Posted: 27 Aug 2012 05:00 PM PDT Researchers have shown that The Liverpool Lung Project Risk Model is effective in identifying those at the highest risk for lung cancer within 5 years, and who are therefore suitable for computed tomography screening.

TREVO 2 adds momentum to mechanical intervention for stroke Posted: 27 Aug 2012 05:00 PM PDT Patients with large vessel occlusion stroke are more likely to achieve reperfusion if treated with the Trevo retriever than with the Merci retriever, say the TREVO 2 investigators.

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