Medical News

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• Frontal-amygdala connectivity alterations in BDI patients
• Four predictors for relapse in FEP patients identified
• Neutrophils help kick off insulin resistance in obesity
• Researchers call for digital rectal exam revival
• Immigration influences HIV diagnosis demographics
• ‘Green’ disinfectant shows promise against hospital-acquired infections
• Neutrophils help kick off insulin resistance in obesity
• Folate, excision biomarkers not predictive for small-cell lung cancer response
• Elderly NSC lung cancer patients benefit from concurrent chemoradiation
• Lung cancer patients can be screened for ALK-inhibitor suitability
• Increases in NSCLC survival 'an artefact of PET assessment'
• Progression-free NSCLC survival boosted by dacomitinib
• VEGF inhibitor fails to improve nonsquamous NSCLC overall survival
• Vulvodynia confers risk for other chronic pain syndromes
• Work solvent-related brain tumor concerns allayed
• Hospice cancer patients adhere well to pain meds
• Study highlights uncertain value of tachypnea at triage

Frontal-amygdala connectivity alterations in BDI patients Posted: 08 Aug 2012 05:00 PM PDT Results from a US study suggest there is dysfunction in the neural networks responsible for emotion regulation among patients with bipolar I disorder, even during periods of euthymia.

Four predictors for relapse in FEP patients identified Posted: 08 Aug 2012 05:00 PM PDT Medication non-adherence, persistent substance use disorder, carers' critical comments, and poorer premorbid adjustment are significant predictors for relapse in patients treated for a first episode of psychosis, a review and meta-analysis of published studies shows.

Neutrophils help kick off insulin resistance in obesity Posted: 07 Aug 2012 05:00 PM PDT Experts have found that neutrophils play an important role in initiating the chronic inflammation that characterizes obesity-induced insulin resistance.

Researchers call for digital rectal exam revival Posted: 07 Aug 2012 05:00 PM PDT Rates of digital rectal examination are low in clinical practice and levels of sufficient training in the technique may be in decline, the results of a US study suggest.

Immigration influences HIV diagnosis demographics Posted: 07 Aug 2012 05:00 PM PDT HIV-positive individuals born outside the USA are a heterogenous population but have significant demographic differences to infected patients born within in the USA, research reveals.

‘Green’ disinfectant shows promise against hospital-acquired infections Posted: 07 Aug 2012 05:00 PM PDT Research shows that the polyhexamethylene-guanidine hydrochloride-based disinfectant Akwaton effectively destroys Bacillus subtilis spores even at low concentrations.

Neutrophils help kick off insulin resistance in obesity Posted: 07 Aug 2012 05:00 PM PDT Experts have found that neutrophils play an important role in initiating the chronic inflammation that characterizes obesity-induced insulin resistance.

Folate, excision biomarkers not predictive for small-cell lung cancer response Posted: 07 Aug 2012 05:00 PM PDT Biomarkers associated with the folate metabolism and excision repair pathways are not sufficiently prognostic to aid chemotherapy decisions for patients with extensive-stage disease small-cell lung cancer, results of a phase III trial show.

Elderly NSC lung cancer patients benefit from concurrent chemoradiation Posted: 07 Aug 2012 05:00 PM PDT Fit older adults with locally advanced non-small-cell lung cancer reap similar benefit from concurrent chemoradiation with etoposide and cisplatin as younger patients, but experience higher rates of hospitalization and toxicity, research shows.

Lung cancer patients can be screened for ALK-inhibitor suitability Posted: 07 Aug 2012 05:00 PM PDT Anaplastic lymphoma kinase gene status in patients with lung adenocarcinoma can be determined non-invasively using circulating tumor cells, research shows.

Increases in NSCLC survival 'an artefact of PET assessment' Posted: 07 Aug 2012 05:00 PM PDT There has been no increase in survival among non-small-cell lung cancer patients in recent years, with evidence suggesting otherwise likely due to positron emission tomography-induced stage migration and selection bias, say US scientists.

Progression-free NSCLC survival boosted by dacomitinib Posted: 07 Aug 2012 05:00 PM PDT In patients with non-small-cell lunch cancer, dacomitinib confers a significant progression-free survival benefit over erlotinib across a range of clinical and molecular subgroups, the results of an international study indicate.

VEGF inhibitor fails to improve nonsquamous NSCLC overall survival Posted: 07 Aug 2012 05:00 PM PDT Adding motesanib to carboplatin–paclitaxel does not boost overall survival in patients with advanced nonsquamous non-small-cell lung cancer, including those with adenocarcinoma, say MONET1 investigators.

Vulvodynia confers risk for other chronic pain syndromes Posted: 07 Aug 2012 05:00 PM PDT Women who experience vulvodynia are more likely than those without the pain syndrome to have fibromyalgia, interstitial cystitis, and irritable bowel syndrome, research suggests.

Work solvent-related brain tumor concerns allayed Posted: 07 Aug 2012 05:00 PM PDT There is no consistent evidence for increased risk for glioma or meningioma following occupational exposure to chlorinated solvents, say researchers.

Hospice cancer patients adhere well to pain meds Posted: 07 Aug 2012 05:00 PM PDT Study results from the midwest USA indicate that hospice-treated older individuals with cancer are highly adherent to pain medication, but that as they become more comfortable, adherence wanes.

Study highlights uncertain value of tachypnea at triage Posted: 07 Aug 2012 05:00 PM PDT The usual method of assessing respiratory rate at triage in the emergency department is highly insensitive for the presence of tachypnea, say researchers.

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