Medical News

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• Smoking may delay full onset of schizophrenia
• <i>GST</i> polymorphisms linked to early-onset bipolar disorder
• Reversible FIXa inhibition a promising anticoagulant approach in PCI
• Early presentation creates thrombolysis delays
• Men opt-out of prostate cancer screening for practical reasons
• Genetic mutations can dictate breast tumor subtype
• <i>BRCA</i>ness profile indicates improved outcome for ovarian cancer patients
• Number of contraceptive packs given affects continuation rate
• Oral contraception improves ART success in women with endometriosis
• Diabetes in menopause influences bone loss and fracture risk
• <i>BRCA</i>ness profile indicates improved outcome for ovarian cancer patients
• Women should achieve a healthy weight before getting pregnant
• Metabolically healthy obesity prevalence varies markedly with criteria
• LDL cholesterol screening low in young US adults, regardless of CHD risk
• Diabetes increases SCD risk post-MI
• β-cell function declines quickly after hyperglycemic pregnancy
• Complete revascularization may increase survival after PCI
• Reversible anticoagulation system shows promise for PCI patients
• Biologics may be cost effective long term in high-need psoriasis patients

Smoking may delay full onset of schizophrenia Posted: 09 Aug 2010 05:00 PM PDT Individuals with schizophrenia who are current or ex-cigarette smokers may be older at the onset of symptoms than their peers who have never smoked, study results show.

<i>GST</i> polymorphisms linked to early-onset bipolar disorder Posted: 09 Aug 2010 05:00 PM PDT Polymorphisms in genes encoding glutathione S-transferase detoxification enzymes modify risk for developing early-onset bipolar disorder, study results show.

Reversible FIXa inhibition a promising anticoagulant approach in PCI Posted: 08 Aug 2010 05:00 PM PDT A novel system reversibly targeting factor IXa allows controlled anticoagulation in patients undergoing percutaneous coronary intervention, a phase IIa study shows.

Early presentation creates thrombolysis delays Posted: 08 Aug 2010 05:00 PM PDT Patients who present at hospital within an hour of stroke symptom onset wait longer to receive thrombolysis than those who present later in the 3-hour treatment window, study results show.

Men opt-out of prostate cancer screening for practical reasons Posted: 08 Aug 2010 05:00 PM PDT The reasons men do not attend prostate cancer screening are mostly practical, and include forgetting their invitation, and having already had previous prostate-specific antigen testing, show Finnish study results.

Genetic mutations can dictate breast tumor subtype Posted: 08 Aug 2010 05:00 PM PDT Deletion of the retinoblastoma gene in mouse mammary progenitor cells induces luminal-B or triple-negative tumor subtypes depending on mutations of the tumor-suppressor protein p53, study findings indicate.

<i>BRCA</i>ness profile indicates improved outcome for ovarian cancer patients Posted: 08 Aug 2010 05:00 PM PDT The breast cancer, early onset gene status of women with epithelial ovarian cancer correlates with their response to chemotherapy and their survival outcome probabilities, according to US researchers.

Number of contraceptive packs given affects continuation rate Posted: 08 Aug 2010 05:00 PM PDT An enhanced supply of oral contraceptives at method initiation increases continuation rates, show US study results.

Oral contraception improves ART success in women with endometriosis Posted: 08 Aug 2010 05:00 PM PDT Short-term oral contraceptive use by women with severe endometriosis results in similar success rates after assisted reproduction treatment as in women without the condition, study findings show.

Diabetes in menopause influences bone loss and fracture risk Posted: 08 Aug 2010 05:00 PM PDT Women with diabetes mellitus experience a higher rate of bone fracture than women without the condition, possibly as a result of experiencing menopause earlier, indicate US study results.

<i>BRCA</i>ness profile indicates improved outcome for ovarian cancer patients Posted: 08 Aug 2010 05:00 PM PDT The breast cancer, early onset gene status of women with epithelial ovarian cancer correlates with their response to chemotherapy and their survival outcome probabilities, according to US researchers.

Women should achieve a healthy weight before getting pregnant Posted: 08 Aug 2010 05:00 PM PDT UK guidelines have outlined the health risks associated with obesity in pregnancy, dispelling the myth that women should 'eat for two,' and urging them to achieve and maintain a healthy weight before, during, and after pregnancy.

Metabolically healthy obesity prevalence varies markedly with criteria Posted: 08 Aug 2010 05:00 PM PDT The prevalence of metabolically healthy obesity varies considerably according to the criteria used, European researchers have warned.

LDL cholesterol screening low in young US adults, regardless of CHD risk Posted: 08 Aug 2010 05:00 PM PDT US research suggests that less than half of young adults may be screened for high levels of low-density lipoprotein cholesterol, regardless of the number of risk factors they have for coronary heart disease.

Diabetes increases SCD risk post-MI Posted: 08 Aug 2010 05:00 PM PDT Patients with diabetes have a higher risk for sudden cardiac death after myocardial infarction than those without diabetes, researchers suggest.

β-cell function declines quickly after hyperglycemic pregnancy Posted: 08 Aug 2010 05:00 PM PDT Study results indicate that women who have gestational diabetes mellitus or gestational impaired glucose tolerance during pregnancy exhibit rapid decline in pancreatic β-cell function during the first year postpartum compared with women with normoglycemic pregnancy.

Complete revascularization may increase survival after PCI Posted: 08 Aug 2010 05:00 PM PDT Complete revascularization of all coronary segments during percutaneous coronary intervention is associated with improved overall survival in patients with multivessel coronary artery disease, a German study reports.

Reversible anticoagulation system shows promise for PCI patients Posted: 08 Aug 2010 05:00 PM PDT Results from a phase IIa study demonstrate that reversible anticoagulation can be carried out successfully in percutaneous coronary intervention patients using the direct factor IXa inhibitor RB006 and its active control agent RB007.

Biologics may be cost effective long term in high-need psoriasis patients Posted: 20 May 2010 05:00 PM PDT The high costs of biologic therapies may be off-set by reducing long hospitalizations in high-need psoriasis patients, shows a study comparing direct costs before and after biologics were introduced.

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