Medical News

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• Brain regions linked to poor insight in first-onset psychosis confirmed
• Risk factors predicting subthreshold expression of bipolar psychopathology identified
• Endoscopic imaging identifies most BE patients with early neoplasia
• Highly sensitive TnT assays improve pulmonary embolism risk stratification
• Many stroke patients fail to adhere to secondary prevention regimen
• Post-prostatectomy pelvic floor training improves continence recovery
• Surgeon skill predicts PSMs at prostatectomy, influencing likelihood of recurrence
• Post-prostatectomy pelvic floor training improves continence recovery
• Surgeon skill predicts PSMs at prostatectomy, influencing likelihood of recurrence
• SLNB not recommended for multiple synchronous breast tumors
• Cholesterol balance linked with aortic arch atherosclerosis
• Low-carb diet causes profound increase in HDL cholesterol
• Metabolic syndrome only predicts severe atherosclerosis in nondiabetics
• Retinopathy prevalence high in US adults with diabetes
• Early therapeutic cooling may not improve out-of-hospital cardiac arrest outcomes
• Early transnasal cooling aids attainment of therapeutic temperatures
• SLNB not recommended for multiple synchronous breast tumors
• CDC reporting tool reveals acceptable prostatectomy complication rates
• Oral contraceptives increase breast cancer risk in African-American women
• Mechanism of curcumin prostate cancer suppression revealed
• Chromogranin A expression linked to prostate cancer biochemical failure
• <i>POLQ</i> overexpression linked to breast cancer relapse
• Men opt-out of prostate cancer screening for practical reasons
• Genetic mutations can dictate breast tumor subtype

Brain regions linked to poor insight in first-onset psychosis confirmed Posted: 12 Aug 2010 05:00 PM PDT Results from a UK study indicate that the cingulate gyrus and the right precuneus/cuneus areas of the brain are involved in poor insight among patients with a first-onset psychosis.

Risk factors predicting subthreshold expression of bipolar psychopathology identified Posted: 12 Aug 2010 05:00 PM PDT Different risk factors are associated with the onset and persistence of subthreshold mania and depression symptoms in young people, researchers have found.

Endoscopic imaging identifies most BE patients with early neoplasia Posted: 12 Aug 2010 05:00 PM PDT Stepwise four-quadrant biopsies are unnecessary for detection of early neoplasias in Barrett's esophagus patients attending specialized high-volume centers with permanent quality control, say researchers.

Highly sensitive TnT assays improve pulmonary embolism risk stratification Posted: 11 Aug 2010 05:00 PM PDT Highly sensitive troponin T assays improve the risk stratification of patients with acute pulmonary embolism by ruling out an adverse early outcome, German researchers report.

Many stroke patients fail to adhere to secondary prevention regimen Posted: 11 Aug 2010 05:00 PM PDT A quarter of stroke patients stop taking at least one of their secondary prevention therapies within 3 months of starting, show findings from the AVAIL registry.

Post-prostatectomy pelvic floor training improves continence recovery Posted: 11 Aug 2010 05:00 PM PDT Research shows that early postoperative pelvic floor muscle training speeds up the recovery of urinary incontinence in the 12 months after radical prostatectomy.

Surgeon skill predicts PSMs at prostatectomy, influencing likelihood of recurrence Posted: 11 Aug 2010 05:00 PM PDT The risk for a positive surgical margin at radical prostatectomy is significantly influenced by surgeon volume, report researchers who found lower rates among high- versus low-volume surgeons.

Post-prostatectomy pelvic floor training improves continence recovery Posted: 11 Aug 2010 05:00 PM PDT Research shows that early postoperative pelvic floor muscle training speeds up the recovery of urinary incontinence in the 12 months after radical prostatectomy.

Surgeon skill predicts PSMs at prostatectomy, influencing likelihood of recurrence Posted: 11 Aug 2010 05:00 PM PDT The risk for a positive surgical margin at radical prostatectomy is significantly influenced by surgeon volume, report researchers who found lower rates among high- versus low-volume surgeons.

SLNB not recommended for multiple synchronous breast tumors Posted: 11 Aug 2010 05:00 PM PDT A high rate of false negative results has caused French researchers to suggest that sentinal lymph node biopsy should not be recommended to diagnose patients with multiple unilateral synchronous invasive breast cancers.

Cholesterol balance linked with aortic arch atherosclerosis Posted: 11 Aug 2010 05:00 PM PDT High-density lipoprotein cholesterol and the ratio of apolipoprotein B to apolipoprotein A-1 are strong predictors of aortic atherosclerosis, study findings suggest.

Low-carb diet causes profound increase in HDL cholesterol Posted: 11 Aug 2010 05:00 PM PDT Long-term adherence to a low-carbohydrate diet is associated with marked improvements in lipid levels, in particular a large increase in levels of high-density lipoprotein cholesterol, US researchers report.

Metabolic syndrome only predicts severe atherosclerosis in nondiabetics Posted: 11 Aug 2010 05:00 PM PDT The metabolic syndrome is only linked to an increased risk for severe coronary atherosclerotic lesions in non-diabetic Turkish patients with an indication for coronary angiography, a study suggests.

Retinopathy prevalence high in US adults with diabetes Posted: 11 Aug 2010 05:00 PM PDT Over a quarter of US diabetics aged 40 years or older have retinopath, with a particularly high prevalence seen in non-Hispanic Black individuals, show study results published in the Journal of the American Medical Association.

Early therapeutic cooling may not improve out-of-hospital cardiac arrest outcomes Posted: 11 Aug 2010 05:00 PM PDT Patients with an out-of-hospital cardiac arrest who receive therapeutic hypothermia from paramedics prior to hospital arrival do not have better patient discharge outcomes than those receiving therapeutic hypothermia on arrival at hospital, Australian researchers suggest.

Early transnasal cooling aids attainment of therapeutic temperatures Posted: 11 Aug 2010 05:00 PM PDT Pre-hospital transnasal cooling can be performed safely in out-of-hospital cardiac arrest patients and may cool patients to target temperature more quickly than intravascular cooling, a study suggests.

SLNB not recommended for multiple synchronous breast tumors Posted: 11 Aug 2010 05:00 PM PDT A high rate of false negative results has caused French researchers to suggest that sentinal lymph node biopsy should not be recommended to diagnose patients with multiple unilateral synchronous invasive breast cancers.

CDC reporting tool reveals acceptable prostatectomy complication rates Posted: 10 Aug 2010 05:00 PM PDT The overall complication rate following open radical retropubic prostatectomy is acceptable, German researchers have found using the Clavein-Dindo classification.

Oral contraceptives increase breast cancer risk in African-American women Posted: 10 Aug 2010 05:00 PM PDT Oral contraceptive formulations used in recent decades increase the risk for breast cancer in African-American women, with a greater effect for estrogen receptor-negative than positive cancer, US study data show.

Mechanism of curcumin prostate cancer suppression revealed Posted: 09 Aug 2010 05:00 PM PDT Curcumin may play a role in inhibiting androgen expression in prostate cancer cells by downregulating the Wnt/beta-catenin signaling pathway, the results of a preliminary study indicate.

Chromogranin A expression linked to prostate cancer biochemical failure Posted: 09 Aug 2010 05:00 PM PDT Chromogranin A polymorphisms and expression and endothelin-1 expression are both linked to prostate cancer risk, with expression of chromogranin A also predicting biochemical failure, say Japanese researchers.

<i>POLQ</i> overexpression linked to breast cancer relapse Posted: 09 Aug 2010 05:00 PM PDT UK researchers have discovered that overexpression of the DNA polymerase theta gene is associated with a substantially increased risk for breast cancer relapse.

Men opt-out of prostate cancer screening for practical reasons Posted: 08 Aug 2010 05:00 PM PDT The reasons men do not attend prostate cancer screening are mostly practical, and include forgetting their invitation, and having already had previous prostate-specific antigen testing, show Finnish study results.

Genetic mutations can dictate breast tumor subtype Posted: 08 Aug 2010 05:00 PM PDT Deletion of the retinoblastoma gene in mouse mammary progenitor cells induces luminal-B or triple-negative tumor subtypes depending on mutations of the tumor-suppressor protein p53, study findings indicate.

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