Medical News

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• Titrated better than high-flow oxygen in COPD exacerbations
• Antidepressants ‘ineffective’ for bipolar depression
• Research confirms reduced fertility in schizophrenia patients
• Serum S100A12 helps distinguish IBD from IBS patients
• Current rates of pregnancy-related VTE reported
• Carotid, brain imaging data add weight to ABCD²
• CIP2A protein expression could indicate aggressive prostate cancer
• Elevated PCA3 score can predict prostate cancer after negative biopsy
• Benefit of mammography screening is “modest”
• Benefits of lipid-lowering therapy for the very elderly uncertain
• Intravenous apoA-V may have therapeutic value in hypertriglyceridemia
• Low serum potassium levels linked to increased risk for Type 2 diabetes
• Electronic feedback to clinicians improves quality of Type 2 diabetes care
• Novel SERM reduces CHD events in postmenopausal women
• Genetic model predicts 10-year CHD event risk
• Older paternal age does not hinder ART success
• Infertile men rely on partners and clinics for support
• Endometriosis fertility index predicts likelihood of natural conception
• Polytherapy for epilepsy linked with infertility

Titrated better than high-flow oxygen in COPD exacerbations Posted: 26 Oct 2010 05:00 PM PDT Titrated oxygen treatment is associated with lower mortality rates than high-flow oxygen treatment in patients suffering an acute exacerbation of chronic obstructive pulmonary disease, Australian research shows.

Antidepressants ‘ineffective’ for bipolar depression Posted: 26 Oct 2010 05:00 PM PDT Antidepressant medications are no more effective than placebo or other standard treatments for bipolar depression, results from a systematic review and meta-analysis show.

Research confirms reduced fertility in schizophrenia patients Posted: 26 Oct 2010 05:00 PM PDT Results from a systematic review and meta-analysis confirm that individuals with schizophrenia have reduced fertility compared with the general population.

Serum S100A12 helps distinguish IBD from IBS patients Posted: 26 Oct 2010 05:00 PM PDT The calcium binding, pro-inflammatory protein S100A12 is present at higher levels in patients with inflammatory bowel disease than in those with irritable bowel syndrome, say researchers who believe it may serve as an inflammatory marker.

Current rates of pregnancy-related VTE reported Posted: 25 Oct 2010 05:00 PM PDT The incidence of deep vein thrombosis during pregnancy has not changed significantly in recent years, whereas pulmonary embolism appears to have increased, say researchers.

Carotid, brain imaging data add weight to ABCD<sup>2</sup> Posted: 25 Oct 2010 05:00 PM PDT Adding findings from brain and carotid imaging to the ABCD2 score improves the risk stratification of patients with transient ischemic attack, shows a study in The Lancet Neurology.

CIP2A protein expression could indicate aggressive prostate cancer Posted: 25 Oct 2010 05:00 PM PDT Study results show that CIP2A protein expression is not only increased in prostate cancer specimens compared with benign samples, but is linked with more aggressive forms of the disease.

Elevated PCA3 score can predict prostate cancer after negative biopsy Posted: 25 Oct 2010 05:00 PM PDT An elevated Prostate Cancer Antigen 3 score can predict the presence of prostate cancer in men with single or multiple previous negative prostate biopsies, study results show.

Benefit of mammography screening is “modest” Posted: 25 Oct 2010 05:00 PM PDT A study investigating the benefits of mammography screening in Norway has revealed that screening is associated with only a modest reduction in breast cancer mortality.

Benefits of lipid-lowering therapy for the very elderly uncertain Posted: 25 Oct 2010 05:00 PM PDT More data are needed on the optimal level of cholesterol for the very elderly and the associated risks and benefits of lipid-lowering therapy in this age group, says a team of Danish researchers.

Intravenous apoA-V may have therapeutic value in hypertriglyceridemia Posted: 25 Oct 2010 05:00 PM PDT Parenteral administration of apolipoprotein A-V together with reconstituted high-density lipoprotein significantly lowers plasma triglycerides in mice lacking apoA-V, US researchers report.

Low serum potassium levels linked to increased risk for Type 2 diabetes Posted: 25 Oct 2010 05:00 PM PDT Low levels of serum potassium are significantly predictive for incident Type 2 diabetes, show results from the ARIC Study cohort.

Electronic feedback to clinicians improves quality of Type 2 diabetes care Posted: 25 Oct 2010 05:00 PM PDT Giving primary healthcare physicians access to an electronic feedback system with information on all their patients with Type 2 diabetes leads to significantly improved quality of care, say researchers.

Novel SERM reduces CHD events in postmenopausal women Posted: 25 Oct 2010 05:00 PM PDT Daily lasofoxifene 0.5 mg reduces the risk for major coronary heart disease events and stroke in postmenopausal women with osteoporosis, but increases the incidence of venous thromboembolic events, a substudy of the PEARL trial shows.

Genetic model predicts 10-year CHD event risk Posted: 25 Oct 2010 05:00 PM PDT Individuals with an elevated risk for first coronary heart disease event can be identified using a genetic risk score based on 13 single nucleotide polymorphisms, study results show.

Older paternal age does not hinder ART success Posted: 24 Oct 2010 05:00 PM PDT Systematic review results indicate that advanced paternal age does not negatively affect the outcome of assisted reproductive technologies such as IVF.

Infertile men rely on partners and clinics for support Posted: 24 Oct 2010 05:00 PM PDT Infertile men are most likely to rely on their intimate partner and medical providers for support and information, and not on wider sources such as friends and support groups, show Australian study results.

Endometriosis fertility index predicts likelihood of natural conception Posted: 24 Oct 2010 05:00 PM PDT US researchers have developed an endometriosis fertility index using the functional status of women's fallopian tubes, ovaries, and fimbria, to predict their chances of conceiving naturally.

Polytherapy for epilepsy linked with infertility Posted: 24 Oct 2010 05:00 PM PDT Women with epilepsy taking three or more antiepileptic drugs are 18 times more likely to be infertile than those not taking any, show study results using Indian data.

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