Medical News

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• Bipolar adults have selective erythrocyte DHA deficits
• DUP linked to brain morphology in schizophrenia
• Functional dyspepsia increases risk for disordered sleep
• Bivalirudin linked to reduced bleeding complications after PCI
• ‘Tailored’ risk model developed for stroke
• Binge eating common, influenced by menstrual cycle in bipolar women
• Personality traits linked to self-stigma in schizophrenia patients
• DVH constraints, not dose, impact bowel dysfunction after prostate RT
• PSA density cutoff triggers intervention in prostate surveillance patients
• DVH constraints, not dose, impact bowel dysfunction after prostate RT
• Gold nanoshells sensitize tumors to radiation therapy
• PSA density cutoff triggers intervention in prostate surveillance patients
• Mediterranean diet may slow age-related weight gain
• Genetic copy number variants implicated in childhood obesity
• Inhaled corticosteroids modestly increase risk for Type 2 diabetes
• Ranibizumab effective for improving visual acuity in DME patients
• Same day discharge after low-risk PCI could halve medical costs
• Poor clopidogrel responsiveness linked to adverse PCI outcomes
• Gold nanoshells sensitize tumors to radiation therapy
• Prostate IMRT reduces gastrointestinal problems compared with CRT
• NOS2 potential therapy target for ER-negative breast cancers
• CIP2A protein expression could indicate aggressive prostate cancer
• Elevated PCA3 score can predict prostate cancer after negative biopsy
• Benefit of mammography screening is “modest”
• Extended prostate biopsy predicts improved progression-free survival
• High-dose fulvestrant benefits advanced breast cancer patients

Bipolar adults have selective erythrocyte DHA deficits Posted: 28 Oct 2010 05:00 PM PDT Results from a US study show that adults with bipolar disorder and major depressive disorder have reduced erythrocyte docosahexaenoic acid composition compared with mentally healthy individuals.

DUP linked to brain morphology in schizophrenia Posted: 28 Oct 2010 05:00 PM PDT Increased duration of untreated psychosis is associated with decreased regional density in the right limbic area of the brain in patients with schizophrenia, researchers have found.

Functional dyspepsia increases risk for disordered sleep Posted: 28 Oct 2010 05:00 PM PDT Disordered sleep is significantly more common in patients with functional dyspepsia than healthy individuals, show results presented at the American College of Gastroenterology 75th Annual Scientific meeting in San Antonio, Texas, USA.

Bivalirudin linked to reduced bleeding complications after PCI Posted: 27 Oct 2010 05:00 PM PDT A bivalirudin-based anticoagulation strategy is associated with a significantly reduced risk for acute and long-term bleeding complications compared with an unfractionated heparin strategy among patients undergoing percutaneous coronary intervention, US researchers report.

‘Tailored’ risk model developed for stroke Posted: 27 Oct 2010 05:00 PM PDT Researchers have devised a model to estimate the 10-year risk for developing stroke using data from nine European countries and incorporating competing risks.

Binge eating common, influenced by menstrual cycle in bipolar women Posted: 27 Oct 2010 05:00 PM PDT Binge eating is common in women with bipolar disorder and is influenced by menstrual cycle, researchers have found.

Personality traits linked to self-stigma in schizophrenia patients Posted: 27 Oct 2010 05:00 PM PDT Internalized stigma in patients with schizophrenia is associated with certain temperament and character traits, researchers have found.

DVH constraints, not dose, impact bowel dysfunction after prostate RT Posted: 27 Oct 2010 05:00 PM PDT Rectal dose–volume histogram parameters are associated with long-term patient-reported gastrointestinal quality of life after prostate radiation, whereas actual radiation doses are not, report US researchers.

PSA density cutoff triggers intervention in prostate surveillance patients Posted: 27 Oct 2010 05:00 PM PDT Men with prostate cancer whose prostate-specific antigen density is over 0.15 require definitive therapy rather than active surveillance, suggest study findings showing a high risk for tumor progression in this population.

DVH constraints, not dose, impact bowel dysfunction after prostate RT Posted: 27 Oct 2010 05:00 PM PDT Rectal dose–volume histogram parameters are associated with long-term patient-reported gastrointestinal quality of life after prostate radiation, whereas actual radiation doses are not, report US researchers.

Gold nanoshells sensitize tumors to radiation therapy Posted: 27 Oct 2010 05:00 PM PDT Local high temperature treatment delivered by gold nanoshells can make breast tumor cells more sensitive to radiation treatment, US study findings indicate.

PSA density cutoff triggers intervention in prostate surveillance patients Posted: 27 Oct 2010 05:00 PM PDT Men with prostate cancer whose prostate-specific antigen density is over 0.15 require definitive therapy rather than active surveillance, suggest study findings showing a high risk for tumor progression in this population.

Mediterranean diet may slow age-related weight gain Posted: 27 Oct 2010 05:00 PM PDT Spanish researchers say that a Mediterranean dietary pattern is significantly associated with reduced weight gain.

Genetic copy number variants implicated in childhood obesity Posted: 27 Oct 2010 05:00 PM PDT A US study has identified several genetic variations linked with obesity in children.

Inhaled corticosteroids modestly increase risk for Type 2 diabetes Posted: 27 Oct 2010 05:00 PM PDT Patients with respiratory disease treated with inhaled corticosteroids have a modestly increased risk for Type 2 diabetes or progression of existing diabetes, say researchers.

Ranibizumab effective for improving visual acuity in DME patients Posted: 27 Oct 2010 05:00 PM PDT Ranibizumab is effective for improving best corrected visual acuity and central retinal thickness and is well tolerated in patients with diabetic macular edema, show results from the RESOLVE study.

Same day discharge after low-risk PCI could halve medical costs Posted: 27 Oct 2010 05:00 PM PDT Canadian researchers suggest that same-day patient discharge after uncomplicated transradial percutaneous coronary intervention and a single bolus dose of abciximab could reduce typical procedural costs by 50%.

Poor clopidogrel responsiveness linked to adverse PCI outcomes Posted: 27 Oct 2010 05:00 PM PDT Stable coronary artery disease patients who respond poorly to clopidogrel are at increased risk for adverse clinical outcomes at 1 year, study results suggest.

Gold nanoshells sensitize tumors to radiation therapy Posted: 27 Oct 2010 05:00 PM PDT Local high temperature treatment delivered by gold nanoshells can make breast tumor cells more sensitive to radiation treatment, US study findings indicate.

Prostate IMRT reduces gastrointestinal problems compared with CRT Posted: 26 Oct 2010 05:00 PM PDT Men with non-metastatic prostate cancer can expect fewer serious bowel complications after treatment with intensity-modulated radiation therapy than after three-dimensional conformal radiotherapy, report researchers.

NOS2 potential therapy target for ER-negative breast cancers Posted: 26 Oct 2010 05:00 PM PDT High expression of inducible nitric oxide synthase 2 is associated with an aggressive tumor phenotype and poor survival among women with estrogen receptor α–negative breast cancer, US research shows

CIP2A protein expression could indicate aggressive prostate cancer Posted: 25 Oct 2010 05:00 PM PDT Study results show that CIP2A protein expression is not only increased in prostate cancer specimens compared with benign samples, but is linked with more aggressive forms of the disease.

Elevated PCA3 score can predict prostate cancer after negative biopsy Posted: 25 Oct 2010 05:00 PM PDT An elevated Prostate Cancer Antigen 3 score can predict the presence of prostate cancer in men with single or multiple previous negative prostate biopsies, study results show.

Benefit of mammography screening is “modest” Posted: 25 Oct 2010 05:00 PM PDT A study investigating the benefits of mammography screening in Norway has revealed that screening is associated with only a modest reduction in breast cancer mortality.

Extended prostate biopsy predicts improved progression-free survival Posted: 24 Oct 2010 05:00 PM PDT US study results indicate that prostate biopsy protocols involving a greater number of cores are significantly associated with improved biochemical progression-free survival compared with protocols that remove fewer cores.

High-dose fulvestrant benefits advanced breast cancer patients Posted: 24 Oct 2010 05:00 PM PDT Patients taking high-dose fulvestrant for advanced breast cancer experience a longer period without disease progression than patients taking lower-dose fulvestrant, study findings indicate.

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