Medical News

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• LV thrombus common in patients with anterior wall STEMI
• Rapid thrombolysis response predicts good stroke outcome
• Optimum duration of dust mite SLIT proposed
• Increased cognitive impairments in psychotic bipolar patients
• Gray matter deficits linked to insight, negative symptoms in early psychosis
• ApoB/apoA-1 ratio independently predicts CAD risk in African Americans
• <i>APOB</i> mutation associated with increased LDL cholesterol and CVD risk
• Gene polymorphism linked with diabetic CRP levels
• GAD antibodies linked with progression to insulin deficiency
• Expert consensus document clarifies PPI-clopidogrel stance
• Gene targeted by statins found in prostate cancer patients with high BMI
• Researchers identify numerous side effects of AIs for breast cancer
• Vegetable fat linked to reduced atherosclerotic plaques
• Obese adolescents at high risk for severe obesity in adulthood
• Miglitol shows promise for inadequately controlled Type 2 diabetes
• Supervised exercise training could benefit patients with Type 2 diabetes
• Expert consensus document clarifies PPI-clopidogrel stance
• NSTEMI patients often delay going to hospital

LV thrombus common in patients with anterior wall STEMI Posted: 10 Nov 2010 04:00 PM PST Left ventricular thrombus remains a frequent finding in patients with acute anterior wall ST-elevation myocardial infarction treated with percutaneous coronary intervention and antiplatelet therapy, Norwegian researchers report.

Rapid thrombolysis response predicts good stroke outcome Posted: 10 Nov 2010 04:00 PM PST Patients who show marked neurologic improvement within an hour of undergoing intravenous thrombolysis for ischemic stroke are likely to have good functional outcomes 3 months later, research published in the Archives of Neurology shows.

Optimum duration of dust mite SLIT proposed Posted: 10 Nov 2010 04:00 PM PST A 4-year course of sublingual immunotherapy is the optimum duration for allergic rhinitis patients sensitized to dust mite allergens, researchers suggest.

Increased cognitive impairments in psychotic bipolar patients Posted: 10 Nov 2010 04:00 PM PST Results from a systematic review and meta-analysis show that bipolar disorder patients with a history of psychosis have poorer cognitive functioning than such patients without such a history.

Gray matter deficits linked to insight, negative symptoms in early psychosis Posted: 10 Nov 2010 04:00 PM PST Results from a Spanish study suggest that gray matter volume deficits are associated with levels of insight and negative symptoms in patients with first-episode psychosis.

ApoB/apoA-1 ratio independently predicts CAD risk in African Americans Posted: 10 Nov 2010 04:00 PM PST A US study shows that the ratio of apolipoprotein B to A-1 may be useful for predicting coronary artery disease among African Americans, independent of the metabolic syndrome.

<i>APOB</i> mutation associated with increased LDL cholesterol and CVD risk Posted: 10 Nov 2010 04:00 PM PST A US study suggests that a mutation in the apolipoprotein B gene is an important determinant of low-density lipoprotein cholesterol levels in the Old Order Amish, possibly increasing their risk for cardiovascular disease.

Gene polymorphism linked with diabetic CRP levels Posted: 10 Nov 2010 04:00 PM PST Italian researchers have identified a new gene polymorphism associated with the inflammatory marker high-sensitivity C-reactive protein in patients with Type 2 diabetes.

GAD antibodies linked with progression to insulin deficiency Posted: 10 Nov 2010 04:00 PM PST Anti-glutamic acid decarboxylase antibodies predict progression to insulin deficiency in Korean patients with Type 2 diabetes, researchers have revealed.

Expert consensus document clarifies PPI-clopidogrel stance Posted: 09 Nov 2010 04:00 PM PST The use of concomitant proton pump inhibitors and antiplatelet drugs, namely clopidogrel, should follow an individualized approach based on each patient's risk–benefit balance, according to an Expert Consensus Document.

Gene targeted by statins found in prostate cancer patients with high BMI Posted: 09 Nov 2010 04:00 PM PST Study findings show a reduced expression of the lipid metabolism gene stearoyl-CoA desaturase 1 – a known target of statins – in tumor samples from prostate cancer patients with a high body mass index.

Researchers identify numerous side effects of AIs for breast cancer Posted: 09 Nov 2010 04:00 PM PST US researchers have identified several side effects in women receiving aromatase inhibitor therapy for breast cancer that are likely to be related to the extreme estrogen deficiency that the treatment causes.

Vegetable fat linked to reduced atherosclerotic plaques Posted: 09 Nov 2010 04:00 PM PST Spanish researchers say that serum proportions of the vegetable n-3 fatty acid α-linolenic acid are inversely associated with plaque burden in the carotid and femoral arteries of patients with primary dyslipidemia.

Obese adolescents at high risk for severe obesity in adulthood Posted: 09 Nov 2010 04:00 PM PST Obese adolescents are 16 times more likely to develop severe obesity in adulthood than those who are normal weight or overweight, research shows.

Miglitol shows promise for inadequately controlled Type 2 diabetes Posted: 09 Nov 2010 04:00 PM PST Trial findings suggest that miglitol could be a useful adjuvant therapy for Chinese patients with Type 2 diabetes that is inadequately controlled by diet and sulfonylurea treatment.

Supervised exercise training could benefit patients with Type 2 diabetes Posted: 09 Nov 2010 04:00 PM PST Adding supervised physical activity sessions to exercise counseling can improve glycated hemoglobin levels and cardiovascular risk factors in patients with Type 2 diabetes and the metabolic syndrome, trial findings suggest.

Expert consensus document clarifies PPI-clopidogrel stance Posted: 09 Nov 2010 04:00 PM PST The use of concomitant proton pump inhibitors and antiplatelet drugs, namely clopidogrel, should follow an individualized approach based on each patient's risk–benefit balance, according to an Expert Consensus Document.

NSTEMI patients often delay going to hospital Posted: 09 Nov 2010 04:00 PM PST Over 50% of patients with non-ST-elevation myocardial infarction delay going to hospital for more than 2 hours after the onset of symptoms, a US study indicates.

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