Thursday, November 18, 2010

Medical News

Medical News


Microsmia linked to poor outcomes in first-episode psychosis patients

Posted: 18 Nov 2010 04:00 PM PST

The presence of olfactory identification deficits in patients with first-episode psychosis is associated with poorer outcomes after treatment, research shows.

Bipolar patients show age-related differences in Axis I comorbidity

Posted: 18 Nov 2010 04:00 PM PST

Results from an Italian study suggest that patterns of Axis I comorbidity differ by age among patients with bipolar disorder.

Predictors of pharyngeal acid reflux discovered

Posted: 18 Nov 2010 04:00 PM PST

Being overweight, having symptoms of classic reflux, and hiatus hernia are all independent predictors of pharyngeal acid reflux in patients with possible reflux laryngitis, report researchers.

Pharmacists’ participation in warfarin management may reduce bleeding

Posted: 17 Nov 2010 04:00 PM PST

Pharmacist-participated warfarin therapy management may halve the total bleeding risk among anticoagulated patients, results of a systematic review show.

Comorbidities may worsen long-term HRQoL after prostate treatment

Posted: 17 Nov 2010 04:00 PM PST

Low-risk prostate cancer patients with severe pretreatment comorbidities are more likely to have a worse baseline and long-term future health-related quality of life compared with men whose pretreatment comorbidities are less severe, say researchers.

Annual mammogram may reduce mortality in women with family breast cancer history

Posted: 17 Nov 2010 04:00 PM PST

Yearly mammography screening in women younger than 50 years with an intermediate familial breast cancer risk is likely to increase cancer detection, reduce the risk for advanced stage disease, and decrease mortality, UK study data show.

Genetic variants of <i>TRIB1</i> and <i>GCKR</i> associated with dyslipidemia

Posted: 17 Nov 2010 04:00 PM PST

A cross-sectional population study shows that polymorphisms in the tribbles homolog 1 and glucokinase regulatory protein genes are associated with lipid levels in the general population.

Anacetrapib lowers LDL, raises HDL

Posted: 17 Nov 2010 04:00 PM PST

The investigational cholesterylester transfer protein inhibitor anacetrapib has lowered low-density lipoprotein by 40%, and more than doubled high-density lipoprotein in a randomized trial for safety and efficacy.

Elevated fasting glucose may cause subclinical atherosclerosis

Posted: 17 Nov 2010 04:00 PM PST

Results from a genetic study indicate that elevated fasting glucose levels may be causally associated with increased carotid intima-media thickness – an indicator of subclinical atherosclerosis.

Atorvastatin, metformin more hepato-protective in combination than alone

Posted: 17 Nov 2010 04:00 PM PST

Combining the use of atorvastatin and metformin in rats with Type 2 diabetes and hyperlipidemia produces greater liver protection than each drug in isolation, Portuguese researchers report.

Anacetrapib lowers LDL, raises HDL

Posted: 17 Nov 2010 04:00 PM PST

The investigational cholesterylester transfer protein inhibitor anacetrapib has lowered low-density lipoprotein by 40%, and more than doubled high-density lipoprotein in a randomized trial for safety and efficacy.

GRAVITAS casts serious doubt on high-dose clopidogrel for poor responders

Posted: 17 Nov 2010 04:00 PM PST

Giving high-dose clopidogrel to patients with high on-treatment residual platelet reactivity after percutaneous coronary intervention does not reduce their risk for cardiovascular death or events, compared with standard clopidogrel dosing, research suggests.

Gene therapy does not reduce deaths or amputations from severe CLI patients

Posted: 17 Nov 2010 04:00 PM PST

Research shows that patients with critical limb ischemia who received an angiogenic growth factor in a Phase III trial do not have significantly lower time to death or amputation over 1 year compared with patients who received placebo.

Annual mammogram may reduce mortality in women with family breast cancer history

Posted: 17 Nov 2010 04:00 PM PST

Yearly mammography screening in women younger than 50 years with an intermediate familial breast cancer risk is likely to increase cancer detection, reduce the risk for advanced stage disease, and decrease mortality, UK study data show.

Salvage versus adjuvant prostate RT may not increase risk for all-cause mortality

Posted: 16 Nov 2010 04:00 PM PST

Delaying radiotherapy until prostate-specific antigen failure after radical prostatectomy does not increase the risk for all-cause mortality among men with a slow PSA doubling time compared with undertaking radiation at the time of surgery, say US researchers.

Tumor volume may be outdated as criteria for insignificant prostate cancer

Posted: 16 Nov 2010 04:00 PM PST

Study results confirm that an index tumor volume threshold of 0.5 ml can indicate clinically insignificant prostate cancer, but the researchers call into question its use in future risk classification systems.

High or low E-cadherin expression may predict poor breast cancer outcome

Posted: 16 Nov 2010 04:00 PM PST

Both high and low levels of E-cadherin expression are associated with an unfavorable breast cancer prognosis compared with intermediate levels, Italian researchers report.

PSA still correlates with prostate tumor volume in contemporary patients

Posted: 15 Nov 2010 04:00 PM PST

Prostate-specific antigen correlates significantly with prostate size only in the largest prostate glands, but it is strongly associated with tumor volume in small, medium, or large prostates, show US study results.

Educated women are less likely to die from breast cancer

Posted: 15 Nov 2010 04:00 PM PST

Women are more likely to die after a breast cancer diagnosis if they have low individual socio-economic status or live in a community with low socio-economic status, study findings indicate.

Low prostate weight linked to PSMs in low-risk prostatectomy patients

Posted: 14 Nov 2010 04:00 PM PST

Men with low-risk prostate cancer are more likely to have positive surgical margins after treatment with nerve-sparing robotic-assisted radical prostatectomy if they have a light rather than heavy prostate, researchers report.

Prostate cancer becomes more aggressive with age, could impact screening

Posted: 14 Nov 2010 04:00 PM PST

Study findings show that as men with prostate cancer age, more aggressive disease characteristics emerge, lessening their chances of survival compared with younger men with the disease.

Lasofoxifene is attractive option for breast cancer prevention

Posted: 14 Nov 2010 04:00 PM PST

The selective estrogen-receptor modulator lasofoxifene appears to reduce the risks for both total, and ER-positive invasive breast cancer in postmenopausal women with osteoporosis, the results of a randomized-controlled trial show.

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