Medical News

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• Asthma control in pregnancy linked to asthma risk in offspring
• Asthma education reduces repeat ED visits for children
• ATS, ERS issue joint asthma assessment guidelines
• Shortened integrated bipolar substance use therapy ‘still effective’
• External locus of control linked to psychosis diagnosis and recovery
• Autoimmune reaction causes false positive HIT results in APS
• Severe white matter changes linked to poor long-term stroke survival
• Genomic grade index predicts chemotherapy response in breast cancer patients
• High-intensity ultrasound shows prostate cancer treatment promise
• PCOS diagnosis related to parental history of vascular dysfunction
• Vitrified ovarian tissue transplants result in high pregnancy rates
• Endometrial cancer risk increased by obesity in young adulthood
• Breast cancer risk from family history unaffected by oral contraceptives
• Age at first birth inversely linked to metabolic syndrome
• Bleeding risk with copper intrauterine device ‘explained’
• 3-day hot flash diary sufficient for postmenopausal assessment
• Environment may contribute to change in male-female birth weight difference
• Survival of PSTT associated with time since antecedent pregnancy
• Mutant <i>FOXL2</i> may be involved in pathogenesis of ovarian granulosa-cell tumors
• Cholesterol metabolism gene variants linked to increased carotid IMT
• Visceral fat more strongly linked to metabolic risk factors than subcutaneous fat
• Small HbA1c benefit from pioglitazone addition to insulin regimens
• Diabetes signals high risk in NSTE ACS
• Breastfed babies have lower BMI in adulthood
• Barriers to termination of resuscitation identified

Asthma control in pregnancy linked to asthma risk in offspring Posted: 06 Jul 2009 05:00 PM PDT Uncontrolled, moderate-to-severe asthma in pregnancy is associated with an increased risk for asthma in offspring, researchers have found.

Asthma education reduces repeat ED visits for children Posted: 06 Jul 2009 05:00 PM PDT Educating young children and their parents about asthma management can significantly reduce repeat emergency department visits and hospital admissions among children with the respiratory disease, results of a review show.

ATS, ERS issue joint asthma assessment guidelines Posted: 06 Jul 2009 05:00 PM PDT The American Thoracic Society and the European Respiratory Society have released official defining standards for clinical trials and practice regarding the assessment of asthma.

Shortened integrated bipolar substance use therapy ‘still effective’ Posted: 06 Jul 2009 05:00 PM PDT A shortened version of integrated group therapy is an effective treatment for bipolar disorder patients with substance dependence, with better outcomes than group drug counseling, US study findings indicate.

External locus of control linked to psychosis diagnosis and recovery Posted: 06 Jul 2009 05:00 PM PDT A perception that events in one's life are primarily influenced by external forces is significantly associated with psychosis and fewer periods of recovery, but it is not specific to schizophrenia, say US researchers.

Autoimmune reaction causes false positive HIT results in APS Posted: 05 Jul 2009 05:00 PM PDT A large proportion of patients with antiphospholipid syndrome and/or systemic lupus erythematosus have false-positive heparin-induced thrombocytopenia test results, say researchers.

Severe white matter changes linked to poor long-term stroke survival Posted: 05 Jul 2009 05:00 PM PDT Patients with severe age related white matter changes do not survive as long after acute stroke as patients with moderate or mild ARWMCs, Finnish research suggests.

Genomic grade index predicts chemotherapy response in breast cancer patients Posted: 05 Jul 2009 05:00 PM PDT Genomic grade index is associated with increased response to neoadjuvant chemotherapy in breast cancer patients irrespective of estrogen receptor (ER) status, study results show.

High-intensity ultrasound shows prostate cancer treatment promise Posted: 05 Jul 2009 05:00 PM PDT High-intensity-focused ultrasound offers good short-term biochemical outcomes with few adverse effects in the treatment of localized prostate cancer, the results of a UK study indicate.

PCOS diagnosis related to parental history of vascular dysfunction Posted: 05 Jul 2009 05:00 PM PDT Study results show that a pre-existing diagnosis of polycystic ovary syndrome is related to a parental history of hypertension, heart disease, and stroke in either the mother or father, suggesting a possible genetic contribution to the etiology of this common endocrine disorder.

Vitrified ovarian tissue transplants result in high pregnancy rates Posted: 05 Jul 2009 05:00 PM PDT Auto-transplantation of vitrified ovarian tissue using the cortical grafting technique in women who have lost their fertility as a result of cancer treatment results in a similar success rate as fresh tissue and is highly effective, a study shows.

Endometrial cancer risk increased by obesity in young adulthood Posted: 05 Jul 2009 05:00 PM PDT Young very obese women have an increased risk for endometrial cancer, particularly if they have early menopause, US researchers have discovered.

Breast cancer risk from family history unaffected by oral contraceptives Posted: 05 Jul 2009 05:00 PM PDT The risk for breast cancer is not increased among women with a family history of the disease by the use of oral contraceptives, the results of a systematic review indicate.

Age at first birth inversely linked to metabolic syndrome Posted: 05 Jul 2009 05:00 PM PDT The risk of metabolic syndrome among postmenopausal women decreases with increasing age at first birth, Korean researchers have found in a study that did not reveal associations with other reproductive factors.

Bleeding risk with copper intrauterine device ‘explained’ Posted: 05 Jul 2009 05:00 PM PDT The copper intrauterine device increases cyclooxygenase-2 expression in the endometrium, which may cause the prostaglandin over-production and bleeding experienced by some women, Chinese study findings suggest.

3-day hot flash diary sufficient for postmenopausal assessment Posted: 05 Jul 2009 05:00 PM PDT The optimum duration of a diary assessing menopausal hot flashes is 3 days, conclude US researchers, who say a shorter diary may ease the burden on patients and research staff and be less expensive than a 7-day diary.

Environment may contribute to change in male-female birth weight difference Posted: 05 Jul 2009 05:00 PM PDT The difference in birth weight between male and female neonates has declined in recent years, potentially due to environmental toxicants disrupting androgen action in male fetuses, argue Canadian scientists.

Survival of PSTT associated with time since antecedent pregnancy Posted: 05 Jul 2009 05:00 PM PDT UK researchers have found that 48 months or more since antecedent pregnancy is a good predictor of poor prognosis in patients with placental-site trophoblastic tumors.

Mutant <i>FOXL2</i> may be involved in pathogenesis of ovarian granulosa-cell tumors Posted: 05 Jul 2009 05:00 PM PDT Study results show that recurrent somatic mutations in the winged helix/forkhead transcription factor gene are present in 97 percent of adult-type granulosa-cell tumors.

Cholesterol metabolism gene variants linked to increased carotid IMT Posted: 05 Jul 2009 05:00 PM PDT A common variant of a gene encoding a cholesterol metabolism enzyme is associated with increased intima-media thickness of the common carotid artery, study results suggest.

Visceral fat more strongly linked to metabolic risk factors than subcutaneous fat Posted: 05 Jul 2009 05:00 PM PDT Relative to subcutaneous adipose tissue, visceral adipose tissue significantly impacts on triglyceride concentrations in both men and women and on high-density lipoprotein-cholesterol levels in women, a Japanese study has found.

Small HbA1c benefit from pioglitazone addition to insulin regimens Posted: 05 Jul 2009 05:00 PM PDT Pioglitazone treatment leads to a slightly greater reduction in glycated hemoglobin when added to insulin regimens in patients with inadequately-controlled Type 2 diabetes, but at the expense of increased hypoglycemia and weight gain, according to the results of a meta-analysis published in the journal Plos ONE.

Diabetes signals high risk in NSTE ACS Posted: 05 Jul 2009 05:00 PM PDT Diabetes is associated with increased short-term risk for major adverse cardiovascular and cerebrovascular events and heart failure and long-term risk for mortality in patients with non-ST elevation acute coronary syndrome.

Breastfed babies have lower BMI in adulthood Posted: 05 Jul 2009 05:00 PM PDT Breastfeeding in infancy is associated with lower body mass index and higher levels of high-density lipoprotein cholesterol in adulthood, an analysis of the Framingham Offspring Study cohort has found.

Barriers to termination of resuscitation identified Posted: 05 Jul 2009 05:00 PM PDT The ability to keep to national guidelines for the termination of resuscitation after out-of-hospital cardiac arrest may be affected by local laws, insurer policies, and public expectations, research suggests.

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