Medical News

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• Platelet size may predict response to antiplatelet therapy
• Novel CHADS-based score improves LAAT prediction in AF
• BMI not associated with biochemical failure after prostate cancer treatment
• BMI not associated with biochemical failure after prostate cancer treatment
• Several factors influence breast cancer brain metastasis survival
• Inflammation compromises HDL protective ability
• Key step in early atherogenesis revealed
• Rural-to-urban migration increases risk for diabetes and overweight in India
• High pulse pressure predicts new-onset diabetes in hypertensive patients
• Magnetic nanoparticles could improve stent drug delivery
• Personalized medicine a step closer?
• Several factors influence breast cancer brain metastasis survival

Platelet size may predict response to antiplatelet therapy Posted: 29 Apr 2010 05:00 PM PDT PPre-procedural platelet size is increased in patients with acute coronary syndromes developing early stent thrombosis and correlates positively with future residual platelet reactivity under aspirin and clopidogrel therapy, Polish researchers report.

Novel CHADS-based score improves LAAT prediction in AF Posted: 29 Apr 2010 05:00 PM PDT A modified CHADS2 score combined with echocardiographic measures is a good predictor of left atrial appendage thrombus in patients with atrial fibrillation, report US researchers.

BMI not associated with biochemical failure after prostate cancer treatment Posted: 29 Apr 2010 05:00 PM PDT Researchers have found that body mass index does not indicate whether a prostate cancer patient is likely to experience biochemical failure after radiotherapy or surgery, once potential confounding factors are taken into account.

BMI not associated with biochemical failure after prostate cancer treatment Posted: 29 Apr 2010 05:00 PM PDT Researchers have found that body mass index does not indicate whether a prostate cancer patient is likely to experience biochemical failure after radiotherapy or surgery, once potential confounding factors are taken into account.

Several factors influence breast cancer brain metastasis survival Posted: 29 Apr 2010 05:00 PM PDT Prognostic class, the occurrence of visceral metastasis and the use of systemic treatment after whole brain radiotherapy are the most important factors influencing survival in patients with breast cancer brain metastasis, Polish research shows.

Inflammation compromises HDL protective ability Posted: 29 Apr 2010 05:00 PM PDT High levels of high-density lipoprotein cholesterol are unable to protect men with elevated C-reactive protein levels against cardiovascular events, shows research.

Key step in early atherogenesis revealed Posted: 29 Apr 2010 05:00 PM PDT The deposition of tiny crystals of cholesterol in the arterial wall is one of the earliest events in atherosclerosis, and directly initiates inflammation, indicates a study in Nature.

Rural-to-urban migration increases risk for diabetes and overweight in India Posted: 29 Apr 2010 05:00 PM PDT Migration from a rural to an urban environment in India is associated with increased prevalence of overweight and diabetes, report researchers.

High pulse pressure predicts new-onset diabetes in hypertensive patients Posted: 29 Apr 2010 05:00 PM PDT High pulse pressure increases the risk for new-onset diabetes in Japanese patients with hypertension, show results from the CASE-J trial.

Magnetic nanoparticles could improve stent drug delivery Posted: 29 Apr 2010 05:00 PM PDT Stent-targeted magnetic nanoparticles loaded with paclitaxel resulted in significant inhibition of in-stent restenosis at a relatively low dose of the drug, preliminary research shows.

Personalized medicine a step closer? Posted: 29 Apr 2010 05:00 PM PDT Whole-genome sequencing can provide useful and clinically relevant information for individual patients, suggests a study of a patient with a family history of vascular disease and early sudden death.

Several factors influence breast cancer brain metastasis survival Posted: 29 Apr 2010 05:00 PM PDT Prognostic class, the occurrence of visceral metastasis and the use of systemic treatment after whole brain radiotherapy are the most important factors influencing survival in patients with breast cancer brain metastasis, Polish research shows.

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Health Informatics News

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• Doctor blocks bill on medicating kids
• Patient or fetus -- whose rights prevail?
• As records go digital, cultures clash
• Doctor wrote 1,000 scripts/week
• Medics overwhelmed by injured
• Insurers, state reach pact on cancer
• Latest outrage: home-care scams
• Medicaid to launch huge data project
• Insurer rethinking rules after chat

Doctor blocks bill on medicating kids Posted: 4/30/2010 © Miami Herald Rep. Paige Kreegel, a physician and chair of the Health Care Services Policy Committee, said he didn't know much about the bill, aimed at preventing overmedicating of children in foster care. But he said doctors are already regulated enough.

Patient or fetus -- whose rights prevail? Posted: 1/26/2010 © Associated Press The case of Samantha Burton, who was forced to remain in the hospital for the welfare of her fetus, is drawing attention to the question of whether pregnancy deprives patients of their rights.

As records go digital, cultures clash Posted: By Sammy Mack 1/21/2010 © Health News Florida The switch to electronic medical records has been rocky for doctors in Broward who refused to pay what they called unwarranted charges and were turned over to collections. More disputes are arising as midcareer physicians bump up against the world of high-tech software sales.

Doctor wrote 1,000 scripts/week Posted: By Carol Gentry 1/15/2010 © Health News Florida Since 2004, a Miami psychiatrist has prescribed almost 14 million pills to Medicaid patients at a cost to taxpayers of $43 million, a feverish pace of 1,000 prescriptions a week. A state senator says the doctor should be the "poster boy for tougher enforcement actions."

Medics overwhelmed by injured Posted:  1/14/2010 © New York Times First aid responders and doctors tried to triage the massive number of injured in Haiti as the death toll estimate rose to 45,000. They didn't even have aspirin, much less anesthesia.

Insurers, state reach pact on cancer Posted: By Christine Jordan Sexton 1/13/2010 © Health News Florida The state’s largest insurance companies on Wednesday said they have signed a voluntary pact committing them to cover routine medical treatments for cancer patients who enroll in clinical trials.

Latest outrage: home-care scams Posted: 12/7/2009 © Associated Press A new report says scams in Miami- Dade brought half a billion dollars in Medicare payments for home health-care into the county last year, more than the entire rest of the nation combined. Many "patients" got big-screen TVs or free maid service.

Medicaid to launch huge data project Posted: By Christine Jordan Sexton 11/13/2009 © Health News Florida  Florida is preparing to make the health histories of more than 1 million Medicaid patients accessible to 80,000 doctors, clinics and hospitals in the state on a secured-access system, the project director said Thursday. The aims: improve patient care, avoid duplication.

Insurer rethinking rules after chat Posted: By Christine Jordan Sexton 11/4/2009 © Health News Florida Following a meeting with Sen. Don Gaetz, the state’s largest health insurer is examining its policies for providing health insurance to cancer patients who undergo clinical trials.

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Medical News

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• Gender differences in COPD expression identified
• CCR8 expression increased in asthma
• Low blood folate levels linked to asthma
• Verbal fluency task reveals inherited neural abnormalities in bipolar disorder
• rTMS shows benefits for negative symptoms in schizophrenia
• Antireflux surgery does not prevent esophageal adenocarcinoma
• Proactive PE follow-up does not increase CTEPH detection
• Early dual antiplatelet therapy cuts microemboli risk after cerebral stenosis
• Plaque hemorrhage, vessel density predict vascular outcomes
• PSA doubling time does not predict recurrence in high-grade disease
• <i>EGFR</i> polymorphism predicts recurrence after radical prostatectomy
• PSA doubling time does not predict recurrence in high-grade disease
• <i>EGFR</i> polymorphism predicts recurrence after radical prostatectomy
• Breast cancer risk assessment tools could be improved
• Discounting obesity identifies ‘high-risk’ metabolic syndrome patients
• Plaque hemorrhage, vessel density predict vascular outcomes
• Levels of hydrogen sulfide reduced in Type 2 diabetes
• Hyperbaric oxygen therapy helps heal diabetic foot ulcers
• OPCAB inferior to conventional CABG in the long term
• rhNRG-1 improves cardiac function of CHF patients
• Breast cancer risk assessment tools could be improved
• Blood biomarkers could dramatically reduce prostate biopsy rates
• Low-dose tamoxifen ‘promising’ for highly endocrine-responsive DIN
• Statin use may lower prostate cancer risk recurrence in RT-treated patients
• Early diagnosis might mean overdiagnosis for prostate cancer
• Breast cancer risk factors differ by ethnicity
• Men of low socioeconomic status less likely to receive radical prostate treatment
• MIS level does not predict breast cancerpost-chemotherapy menstrual status

Gender differences in COPD expression identified Posted: 29 Apr 2010 05:00 PM PDT Results from a study conducted in Latin America show significant gender differences in perception of dyspnea and health status among individuals with and without chronic obstructive pulmonary disease.

CCR8 expression increased in asthma Posted: 29 Apr 2010 05:00 PM PDT Expression of the chemokine receptor 8 protein is increased in blood and airway cells from patients with asthma, research shows.

Low blood folate levels linked to asthma Posted: 29 Apr 2010 05:00 PM PDT Low blood levels of folate are associated with an increased prevalence of asthma in adults, researchers have found.

Verbal fluency task reveals inherited neural abnormalities in bipolar disorder Posted: 29 Apr 2010 05:00 PM PDT Bipolar disorder may be associated with an inherited abnormality of a neural network that incorporates the left prefrontal cortex and bilateral retrosplenial cortex, study findings suggest.

rTMS shows benefits for negative symptoms in schizophrenia Posted: 29 Apr 2010 05:00 PM PDT Prefrontal repetitive transcranial magnetic stimulation may be a beneficial treatment for negative symptoms in patients with schizophrenia, meta-analysis findings suggest.

Antireflux surgery does not prevent esophageal adenocarcinoma Posted: 29 Apr 2010 05:00 PM PDT Antireflux surgery does not prevent development of esophageal or cardia adenocarcinoma in patients with reflux, show study results.

Proactive PE follow-up does not increase CTEPH detection Posted: 28 Apr 2010 05:00 PM PDT Proactive follow-up after pulmonary embolism does not increase the number of patients diagnosed with chronic thromboembolic pulmonary hypertension, Dutch researchers have found.

Early dual antiplatelet therapy cuts microemboli risk after cerebral stenosis Posted: 28 Apr 2010 05:00 PM PDT Early combination antiplatelet therapy results in fewer microemboli relative to aspirin monotherapy in patients with symptomatic cerebral or carotid artery stenosis, show results of the CLAIR study.

Plaque hemorrhage, vessel density predict vascular outcomes Posted: 28 Apr 2010 05:00 PM PDT Patients with hemorrhage or notable vessel formation in excised carotid artery plaques are at increased risk for vascular events or death, research shows.

PSA doubling time does not predict recurrence in high-grade disease Posted: 28 Apr 2010 05:00 PM PDT The predictive value of prostate-specific antigen doubling time decreases in advanced stage prostate cancer, report US researchers.

<i>EGFR</i> polymorphism predicts recurrence after radical prostatectomy Posted: 28 Apr 2010 05:00 PM PDT Researchers have identified a single nucleotide polymorphism flanking the epidermal growth factor gene which independently predicts biochemical recurrence after radical prostatectomy for prostate cancer.

PSA doubling time does not predict recurrence in high-grade disease Posted: 28 Apr 2010 05:00 PM PDT The predictive value of prostate-specific antigen doubling time decreases in advanced stage prostate cancer, report US researchers.

<i>EGFR</i> polymorphism predicts recurrence after radical prostatectomy Posted: 28 Apr 2010 05:00 PM PDT Researchers have identified a single nucleotide polymorphism flanking the epidermal growth factor gene which independently predicts biochemical recurrence after radical prostatectomy for prostate cancer.

Breast cancer risk assessment tools could be improved Posted: 28 Apr 2010 05:00 PM PDT None of the current breast cancer risk assessment tools fully discriminate between women who will and women who will not develop breast cancer, a review by Canadian researchers has shown.

Discounting obesity identifies ‘high-risk’ metabolic syndrome patients Posted: 28 Apr 2010 05:00 PM PDT Removing obesity from the metabolic syndrome criteria identifies a group of patients at high short-term cardiovascular risk, say researchers.

Plaque hemorrhage, vessel density predict vascular outcomes Posted: 28 Apr 2010 05:00 PM PDT Patients with hemorrhage or notable vessel formation in excised carotid artery plaques are at increased risk for vascular events or death, research shows.

Levels of hydrogen sulfide reduced in Type 2 diabetes Posted: 28 Apr 2010 05:00 PM PDT Individuals with Type 2 diabetes and who are overweight have low plasma levels of hydrogen sulfide, show study results.

Hyperbaric oxygen therapy helps heal diabetic foot ulcers Posted: 28 Apr 2010 05:00 PM PDT Results from the HODFU study show that hyperbaric oxygen therapy significantly improves the healing of diabetic foot ulcers when added to normal treatment.

OPCAB inferior to conventional CABG in the long term Posted: 28 Apr 2010 05:00 PM PDT Patients who undergo off-pump coronary artery bypass are less likely to experience problems in the short term than patients who undergo conventional coronary artery bypass graft, but they face increased risks for repeat revascularization and major vascular events in the long term, researchers report.

rhNRG-1 improves cardiac function of CHF patients Posted: 28 Apr 2010 05:00 PM PDT Short-term administration of recombinant human neuregulin-1 could results in sustained improvement of cardiac pumping and inhibition or reversal of ventricular remodeling in patients with chronic heart failure, researchers report.

Breast cancer risk assessment tools could be improved Posted: 28 Apr 2010 05:00 PM PDT None of the current breast cancer risk assessment tools fully discriminate between women who will and women who will not develop breast cancer, a review by Canadian researchers has shown.

Blood biomarkers could dramatically reduce prostate biopsy rates Posted: 27 Apr 2010 05:00 PM PDT Research results show that testing levels of free and intact prostate-specific antigen and kallikrein-related peptidase 2 in addition to total PSA, can successfully predict the result of prostate biopsy in men with raised PSA levels.

Low-dose tamoxifen ‘promising’ for highly endocrine-responsive DIN Posted: 27 Apr 2010 05:00 PM PDT Women diagnosed with a highly hormone-responsive breast ductal intraepithelial neoplasia have a reduced risk for relapse with tamoxifen treatment, , Italian research shows.

Statin use may lower prostate cancer risk recurrence in RT-treated patients Posted: 26 Apr 2010 05:00 PM PDT Research indicates that men undergoing radiation therapy for prostate cancer are more likely to remain relapse free, and less likely to experience biochemical disease recurrence, if they use statins before or during treatment.

Early diagnosis might mean overdiagnosis for prostate cancer Posted: 26 Apr 2010 05:00 PM PDT Prostate cancer and other oncology patients must be adequately informed of the nature and magnitude of the trade-off involved with early cancer detection, say US researchers investigating the theory that early detection is always better.

Breast cancer risk factors differ by ethnicity Posted: 26 Apr 2010 05:00 PM PDT Breast cancer risk factors established in White women have less influence on breast cancer risk in Hispanic women, US researchers report.

Men of low socioeconomic status less likely to receive radical prostate treatment Posted: 25 Apr 2010 05:00 PM PDT Men who live in deprived areas are less likely to be given radical treatment for prostate cancer than men who live in affluent areas, according to UK research.

MIS level does not predict breast cancerpost-chemotherapy menstrual status Posted: 25 Apr 2010 05:00 PM PDT For premenopausal women undergoing chemotherapy for breast cancer, neither the baseline measurement nor a reduction of serum mullerian inhibitory substance, a marker of ovarian reserve, predict the future return of menses, US researchers report.

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