Medical News

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• Excessive supraventricular ectopic activity predicts AF, stroke
• Parental reports overestimate wheezing in children
• Pregnant women at increased mortality risk from swine flu
• Long-term azithromycin treatment may benefit COPD patients with a tracheostomy
• Speech misattribution bias in schizophrenia offers clue to hallucinations
• Hippocampal function distinguishes bipolar disorder from schizophrenia
• <i>NOD2</i> variants not associated with Crohn’s disease
• Clopidogrel discontinuation leads to CV event cluster in ACS patients
• Cerebrovascular reactivity linked to ischemia risk after SAH
• Inhibition of Bmi-1 protein could halt prostate tumor growth
• Inhibition of Bmi-1 protein could halt prostate tumor growth
• Critical role for protein in the development of aggressive breast cancer
• Variants in <i>ACAD10</i> linked to insulin resistance and lipid oxidation
• Low baseline LDL predicts LDL rise with omega-3 acid ethyl ester
• Mipomersen treatment linked with potential to cause fatty liver
• Variants in <i>ACAD10</i> linked to insulin resistance and lipid oxidation
• Hypertension more prevalent in youth with Type 2 than Type 1 diabetes
• Gene profiling improves rejection surveillance of cardiac transplant patients
• Meta-analysis refutes increase in CV risk from clopidogrel-PPI interaction
• Critical role for protein in the development of aggressive breast cancer
• A man’s estrogen level could predict his prostate cancer risk
• Weight gain at time of prostate cancer surgery increases recurrence risk
• Breast cancer risk may be linked to grandmother's diet
• Prostate biomarkers indicate which surveillance patients will need treatment
• Fibrin glue does not reduce post-breast surgery seroma formation
• Radiation dose outside of the prostate indicates likelihood of treatment failure
• PSA doubling time not a reliable predictor of progression after RP
• Chemotherapy-induced amenorrhea common among premenopausal breast cancer patients

Excessive supraventricular ectopic activity predicts AF, stroke Posted: 22 Apr 2010 05:00 PM PDT The appearance of excessive supraventricular ectopic activity in healthy people predicts stroke, death, and onset of atrial fibrillation, show study results.

Parental reports overestimate wheezing in children Posted: 22 Apr 2010 05:00 PM PDT Parental reports of asthma-like symptoms in preschool children should be confirmed by doctors wherever possible, say researchers who found that parents generally overestimate the prevalence of such symptoms.

Pregnant women at increased mortality risk from swine flu Posted: 22 Apr 2010 05:00 PM PDT Mortality rates due to swine flu (influenza A H1N1) are significantly higher among pregnant women than the general population, US study results show.

Long-term azithromycin treatment may benefit COPD patients with a tracheostomy Posted: 22 Apr 2010 05:00 PM PDT Long-term treatment with the macrolide antibiotic azithromycin reduces exacerbations and hospitalization rates and improves quality of life in chronic obstructive pulmonary disease patients with a tracheostomy, results from a preliminary study suggest.

Speech misattribution bias in schizophrenia offers clue to hallucinations Posted: 22 Apr 2010 05:00 PM PDT Misattribution of self-generated speech to others may underlie auditory verbal hallucinations in patients with schizophrenia, research suggests.

Hippocampal function distinguishes bipolar disorder from schizophrenia Posted: 22 Apr 2010 05:00 PM PDT Activation of the hippocampus and prefrontal cortex during memory encoding and retrieval can help distinguish between schizophrenia and bipolar disorder patients, say researchers.

<i>NOD2</i> variants not associated with Crohn’s disease Posted: 22 Apr 2010 05:00 PM PDT A large Danish study has argued against screening for Crohn's disease in the general population using three genetic variants, despite positive findings in earlier case–control investigations.

Clopidogrel discontinuation leads to CV event cluster in ACS patients Posted: 21 Apr 2010 05:00 PM PDT Patients with acute coronary syndromes are twice as likely to die or experience myocardial infarction if they discontinue clopidogrel treatment within 90 days than those who continue antiplatelet therapy, study findings indicate.

Cerebrovascular reactivity linked to ischemia risk after SAH Posted: 21 Apr 2010 05:00 PM PDT Patients who have progressive loss of cerebrovascular reactivity to carbon dioxide challenge after suffering subarachnoid hemorrhage are at high risk for delayed cerebral ischemia, say researchers.

Inhibition of Bmi-1 protein could halt prostate tumor growth Posted: 21 Apr 2010 05:00 PM PDT Researchers have induced prostate cancer cell death in a zebrafish xenograft model, by targeting a stem cell protein critical to the growth of prostate cancer.

Inhibition of Bmi-1 protein could halt prostate tumor growth Posted: 21 Apr 2010 05:00 PM PDT Researchers have induced prostate cancer cell death in a zebrafish xenograft model, by targeting a stem cell protein critical to the growth of prostate cancer.

Critical role for protein in the development of aggressive breast cancer Posted: 21 Apr 2010 05:00 PM PDT US researchers have identified a protein that may play a significant role in the development of aggressive, human epidermal growth factor receptor 2-driven breast cancer.

Variants in <i>ACAD10</i> linked to insulin resistance and lipid oxidation Posted: 21 Apr 2010 05:00 PM PDT Variants in the acylcoenzyme A dehydrogenase 10 gene are associated with increased risk for Type 2 diabetes, report researchers who believe the increased risk is caused by impaired insulin sensitivity and abnormal lipid oxidation.

Low baseline LDL predicts LDL rise with omega-3 acid ethyl ester Posted: 21 Apr 2010 05:00 PM PDT The addition of prescription omega-3 acid ethyl ester to statin therapy is associated with an increase in low-density lipoprotein cholesterol in a subgroup of patients with mixed dyslipidemia.

Mipomersen treatment linked with potential to cause fatty liver Posted: 21 Apr 2010 05:00 PM PDT Short-term treatment with mipomersen, an apolipoprotein B-100 synthesis inhibitor, leads to a rise in intrahepatic triglyceride content in people with familial hypercholesterolemia, study findings show.

Variants in <i>ACAD10</i> linked to insulin resistance and lipid oxidation Posted: 21 Apr 2010 05:00 PM PDT Variants in the acylcoenzyme A dehydrogenase 10 gene are associated with increased risk for Type 2 diabetes, report researchers who believe the increased risk is caused by impaired insulin sensitivity and abnormal lipid oxidation.

Hypertension more prevalent in youth with Type 2 than Type 1 diabetes Posted: 21 Apr 2010 05:00 PM PDT Children and adolescents with Type 2 diabetes are more likely to have high blood pressure than those with Type 1 diabetes, report US researchers.

Gene profiling improves rejection surveillance of cardiac transplant patients Posted: 21 Apr 2010 05:00 PM PDT Gene-expression profiling reduces the number of biopsies needed to monitor rejection in low-risk cardiac transplant patients, without any increase in serious adverse outcomes, show results of the IMAGE trial.

Meta-analysis refutes increase in CV risk from clopidogrel-PPI interaction Posted: 21 Apr 2010 05:00 PM PDT Meta-analysis findings cast further doubt on the suggestion that concomitant use of proton-pump inhibitors in patients taking clopidogrel is associated with an increase in cardiovascular risk.

Critical role for protein in the development of aggressive breast cancer Posted: 21 Apr 2010 05:00 PM PDT US researchers have identified a protein that may play a significant role in the development of aggressive, human epidermal growth factor receptor 2-driven breast cancer.

A man’s estrogen level could predict his prostate cancer risk Posted: 20 Apr 2010 05:00 PM PDT Researchers have identified a type of estrogen metabolite that is more prevalent in men with prostate cancer than men without the disease, and believe it could be used as a biomarker to assess prostate cancer risk.

Weight gain at time of prostate cancer surgery increases recurrence risk Posted: 20 Apr 2010 05:00 PM PDT Men whose body mass index increases by as little as 1 kg/m2 in the 5 years before and the year after surgery for prostate cancer are twice as likely to experience disease recurrence than men whose body mass index remains stable, study results show.

Breast cancer risk may be linked to grandmother's diet Posted: 20 Apr 2010 05:00 PM PDT Exposure to a high-fat diet during pregnancy may increase the risk for breast cancer in both daughters and granddaughters, US researchers report

Prostate biomarkers indicate which surveillance patients will need treatment Posted: 19 Apr 2010 05:00 PM PDT Novel application of the Prostate Health Index and measurement of DNA content can predict which prostate cancer patients under active surveillance will ultimately need active treatment, US researchers report.

Fibrin glue does not reduce post-breast surgery seroma formation Posted: 19 Apr 2010 05:00 PM PDT The use of fibrin glue does not prevent seroma formation and does not reduce seroma magnitude and duration following axillary lymphadenectomy, Italian researchers report.

Radiation dose outside of the prostate indicates likelihood of treatment failure Posted: 18 Apr 2010 05:00 PM PDT The likelihood of radiotherapy-treated prostate cancer patients experiencing biological or chemical failure is linked to how much radiation reaches beyond the primary target area, Dutch study results show.

PSA doubling time not a reliable predictor of progression after RP Posted: 18 Apr 2010 05:00 PM PDT A man's prostate-specific antigen doubling time after radical prostatectomy for prostate cancer cannot reliably indicate whether he is likely to experience biochemical progression, say US researchers.

Chemotherapy-induced amenorrhea common among premenopausal breast cancer patients Posted: 18 Apr 2010 05:00 PM PDT A considerable proportion of women treated with chemotherapy will experience periods of chemotherapy-induced amenorrhea, but many will resume bleeding, say US researchers.

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