Medical News

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• Eotaxin linked to eosinophil degranulation in asthmatic children
• Infant wheeze risk factors similar in affluent and non-affluent countries
• Severe childhood asthma is distinct airway molecular phenotype
• Soft form bipolar disorder often misdiagnosed as MDD in elderly
• Behavior contributes to relapse in schizophrenia patients with long DUI
• Blood biomarkers could dramatically reduce prostate biopsy rates
• Low-dose tamoxifen ‘promising’ for highly endocrine-responsive DIN
• Circulating BDNF linked with metabolic and cardiovascular health
• PAD patients taking statins may be at decreased risk for death
• Ranibizumab plus laser treatment effective for diabetic macular edema
• Vitamin B therapy can worsen diabetic nephropathy symptoms
• Adding CACS improves risk classification for coronary heart disease
• CT angiography after positive stress tests is cost-effective

Eotaxin linked to eosinophil degranulation in asthmatic children Posted: 28 Apr 2010 05:00 PM PDT The CC chemokine eotaxin, but not the T helper type 2 cytokine interleukin-5, may play an important role in eosinophil degranulation in children with stable asthma, research suggests.

Infant wheeze risk factors similar in affluent and non-affluent countries Posted: 28 Apr 2010 05:00 PM PDT The most important early-life risk factors for recurrent wheeze among infants in both affluent and non-affluent countries are common cold infections and nursery school attendance, research shows.

Severe childhood asthma is distinct airway molecular phenotype Posted: 28 Apr 2010 05:00 PM PDT Severe asthma in children is characterized by distinct molecular patterns of airway inflammation, which may account for ongoing symptoms despite corticosteroid treatment, say US researchers.

Soft form bipolar disorder often misdiagnosed as MDD in elderly Posted: 28 Apr 2010 05:00 PM PDT A considerable number of older patients with bipolar II disorder or bipolar disorder not otherwise specified are initially misdiagnosed as having major depressive disorder, study findings show.

Behavior contributes to relapse in schizophrenia patients with long DUI Posted: 28 Apr 2010 05:00 PM PDT The increased risk for relapse in patients with schizophrenia who have a long duration of untreated illness may be due to them having aspects inherent to the disease that predispose them both to a high risk for relapse and to a delay in admission, say UK researchers.

Blood biomarkers could dramatically reduce prostate biopsy rates Posted: 27 Apr 2010 05:00 PM PDT Research results show that testing levels of free and intact prostate-specific antigen and kallikrein-related peptidase 2 in addition to total PSA, can successfully predict the result of prostate biopsy in men with raised PSA levels.

Low-dose tamoxifen ‘promising’ for highly endocrine-responsive DIN Posted: 27 Apr 2010 05:00 PM PDT Women diagnosed with a highly hormone-responsive breast ductal intraepithelial neoplasia have a reduced risk for relapse with tamoxifen treatment, , Italian research shows.

Circulating BDNF linked with metabolic and cardiovascular health Posted: 27 Apr 2010 05:00 PM PDT Plasma levels of brain-derived neurotrophic factor are associated with several risk factors for the metabolic syndrome and cardiovascular dysfunction, researchers report.

PAD patients taking statins may be at decreased risk for death Posted: 27 Apr 2010 05:00 PM PDT Statins may be associated with a decreased risk for death from all causes and cardiovascular disease in patients with peripheral arterial disease, US research suggests.

Ranibizumab plus laser treatment effective for diabetic macular edema Posted: 27 Apr 2010 05:00 PM PDT Intravitreal ranibizumab plus prompt or deferred laser is more effective than a combination of triamcinolone and laser or laser alone for treating diabetic macular edema, research shows.

Vitamin B therapy can worsen diabetic nephropathy symptoms Posted: 27 Apr 2010 05:00 PM PDT High doses of vitamin B, prescribed to reduce levels of homocysteine, accelerate the progression of diabetic nephropathy, report researchers.

Adding CACS improves risk classification for coronary heart disease Posted: 27 Apr 2010 05:00 PM PDT Patients can be more accurately risk-stratified for the prediction of coronary heart disease events if the amount of calcium in their coronary arteries is taken into account alongside traditional risk factors, research suggests.

CT angiography after positive stress tests is cost-effective Posted: 27 Apr 2010 05:00 PM PDT Non-invasive computed tomography angiography is a cost-effective alternative to invasive cardiac catheterization in patients who have a positive stress test result, no other symptoms, and a less than 50% chance of having significant coronary artery disease, report researchers.

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