Medical News

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• Unreported, untreated COPD exacerbations linked to reduced HRQoL
• Evidence for CV benefits of inhaled corticosteroids in COPD ‘lacking’
• Plethysmography overestimates lung volume in patients with airflow obstruction
• Community study clarifies rapid-cycling bipolar disorder characteristics
• National legislation differences affect patients’ views on involuntary admission
• PSA kinetics unreliable for determining treatment in prostate surveillance patients
• Poor QoL linked to poor chemotherapy response in advanced breast cancer
• Metabolic syndrome linked with impaired LV geometry and myocardial function
• Strong association between Lp-PL₂ and CHD confirmed
• Increased HR variability during sleep increases CVD risk in Type 2 diabetics
• Racial disparity in HbA1c exists in children with diabetes
• Biomarker panel ‘moderately improves’ CHD risk prediction
• Beta blockers beneficial after cardiac surgery

Unreported, untreated COPD exacerbations linked to reduced HRQoL Posted: 05 May 2010 05:00 PM PDT Two or more unreported exacerbations are associated with reduced health-related quality of life in patients with chronic obstructive pulmonary disease, study results show.

Evidence for CV benefits of inhaled corticosteroids in COPD ‘lacking’ Posted: 05 May 2010 05:00 PM PDT A systematic review and meta-analysis of published studies has failed to find strong evidence to suggest that treatment with inhaled corticosteroids reduces risk for myocardial infarction, cardiovascular death, or overall mortality in patients with chronic obstructive pulmonary disease .

Plethysmography overestimates lung volume in patients with airflow obstruction Posted: 05 May 2010 05:00 PM PDT Plethysmography overestimates lung volume compared with the helium dilution method and computed tomography scans in patients with airflow obstruction, research shows.

Community study clarifies rapid-cycling bipolar disorder characteristics Posted: 05 May 2010 05:00 PM PDT A community epidemiological profile based on surveys in 10 diverse countries confirms most but not all current clinically based knowledge on rapid-cycling bipolar disorder.

National legislation differences affect patients’ views on involuntary admission Posted: 05 May 2010 05:00 PM PDT Psychiatric patients' retrospective views on involuntary hospital admission vary significantly between different European countries, research indicates.

PSA kinetics unreliable for determining treatment in prostate surveillance patients Posted: 04 May 2010 05:00 PM PDT US researchers have found that prostate-specific antigen kinetics are not a reliable indicator for therapeutic intervention in men with low-risk prostate cancer on active surveillance programs.

Poor QoL linked to poor chemotherapy response in advanced breast cancer Posted: 04 May 2010 05:00 PM PDT Self-reported health-related quality of life independently predicts chemotherapy treatment benefit and toxicity in women with advanced breast cancer, study findings indicate.

Metabolic syndrome linked with impaired LV geometry and myocardial function Posted: 04 May 2010 05:00 PM PDT The metabolic syndrome is associated with impaired left ventricle geometry and function in patients with calcific aortic stenosis, Canadian research has revealed.

Strong association between Lp-PL<sub>2</sub> and CHD confirmed Posted: 04 May 2010 05:00 PM PDT Lipoprotein-associated phospholipase A2 activity and mass are strongly associated with coronary heart disease, research published in The Lancet suggests.

Increased HR variability during sleep increases CVD risk in Type 2 diabetics Posted: 04 May 2010 05:00 PM PDT Increased heart rate variability during sleep, measured using 24-hour ambulatory blood pressure monitoring, increases the risk for incident cardiovascular disease in Type 2 diabetics, report researchers.

Racial disparity in HbA1c exists in children with diabetes Posted: 04 May 2010 05:00 PM PDT Study results show that African–American children with Type 1 diabetes have significantly higher average levels of glycated hemoglobin, independent of mean blood glucose, than Caucasian children with the condition.

Biomarker panel ‘moderately improves’ CHD risk prediction Posted: 04 May 2010 05:00 PM PDT Adding biomarkers to predictive models based on traditional risk factors led to only moderate improvement in coronary heart disease risk prediction in post-menopausal women, report researchers in the Journal of the American College of Cardiology.

Beta blockers beneficial after cardiac surgery Posted: 04 May 2010 05:00 PM PDT Patients discharged with beta blockers after cardiac surgery have significantly reduced long-term mortality, extending the evidence base for use of beta blockers in this setting, report researchers who analyzed registry data.

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