Medical News

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• Acadesine may be useful for treatment of thrombotic disorders
• Descending aortic plaques exposed as embolic stroke mechanism
• Psoriasis linked to hepatitis C
• Positive surgical margins worsen men’s fear of prostate cancer recurrence
• Positive surgical margins worsen men’s fear of prostate cancer recurrence
• Toremifene potential alternative to tamoxifen for HR-positive breast cancer
• Triglyceride-to-HDL cholesterol ratio predicts mortality in Type 2 diabetics
• Lipid-lowering therapy tied to better outcomes in AF patients
• Genetic variations underlie racial differences in statin response
• No link between <i>INSIG1</i> polymorphisms and Type 2 diabetes
• Triglyceride-to-HDL cholesterol ratio predicts mortality in Type 2 diabetics
• EUROASPIRE III data reveal lifestyle prevention being missed out
• Early follow-up linked to reduced HF readmissions
• Toremifene potential alternative to tamoxifen for HR-positive breast cancer

Acadesine may be useful for treatment of thrombotic disorders Posted: 06 May 2010 05:00 PM PDT Research indicates that the adenosine-regulating agent acadesine inhibits tissue factor expression and thrombus formation by activating the phosphoinositide 3-kinase/Akt pathway.

Descending aortic plaques exposed as embolic stroke mechanism Posted: 06 May 2010 05:00 PM PDT Retrograde blood flow arising from complex plaques in the proximal descending aorta could be an important embolic stroke mechanism, claim researchers.

Psoriasis linked to hepatitis C Posted: 06 May 2010 05:00 PM PDT Patients with psoriasis are at increased risk for hepatitis C, study findings show.

Positive surgical margins worsen men’s fear of prostate cancer recurrence Posted: 06 May 2010 05:00 PM PDT Men treated with surgery after being diagnosed with localized prostate cancer experience greater fear of cancer recurrence if they have positive rather than negative surgical margins, say US researchers.

Positive surgical margins worsen men’s fear of prostate cancer recurrence Posted: 06 May 2010 05:00 PM PDT Men treated with surgery after being diagnosed with localized prostate cancer experience greater fear of cancer recurrence if they have positive rather than negative surgical margins, say US researchers.

Toremifene potential alternative to tamoxifen for HR-positive breast cancer Posted: 06 May 2010 05:00 PM PDT US researchers report that tamoxifen and toremifene are equivalent, in terms of therapeutic efficacy, for the treatment of hormone receptor-positive breast cancer.

Triglyceride-to-HDL cholesterol ratio predicts mortality in Type 2 diabetics Posted: 06 May 2010 05:00 PM PDT Study results show that an elevated ratio of triglyceride to high-density lipoprotein cholesterol is associated with increased all-cause and cardiovascular mortality in people with Type 2 diabetes.

Lipid-lowering therapy tied to better outcomes in AF patients Posted: 06 May 2010 05:00 PM PDT Lipid-lowering therapy in patients with atrial fibrillation is associated with a reduction in cardiovascular events and mortality, a post-hoc analysis of the AFFIRM study suggests.

Genetic variations underlie racial differences in statin response Posted: 06 May 2010 05:00 PM PDT Common variants in the genes encoding low-density lipoprotein receptor and 3-hydroxy-3-methylglutaryl-coenzyme A reductase attenuate the lipid-lowering response to simvastatin therapy, US researchers report.

No link between <i>INSIG1</i> polymorphisms and Type 2 diabetes Posted: 06 May 2010 05:00 PM PDT Polymorphisms in the insulin-induced gene 1 do not significantly influence risk for Type 2 diabetes or obesity, report researchers.

Triglyceride-to-HDL cholesterol ratio predicts mortality in Type 2 diabetics Posted: 06 May 2010 05:00 PM PDT Study results show that an elevated ratio of triglyceride to high-density lipoprotein cholesterol is associated with increased all-cause and cardiovascular mortality in people with Type 2 diabetes.

EUROASPIRE III data reveal lifestyle prevention being missed out Posted: 06 May 2010 05:00 PM PDT Data from the EUROASPIRE III survey reveal that primary and secondary cardiovascular prevention treatment goals are not being met in the majority of patients, despite increased use of preventive cardiovascular medications.

Early follow-up linked to reduced HF readmissions Posted: 06 May 2010 05:00 PM PDT Patients who receive early follow-up from a physician after being admitted to hospital for heart failure (HF) have a reduced chance of being readmitted within 30 days, research shows.

Toremifene potential alternative to tamoxifen for HR-positive breast cancer Posted: 06 May 2010 05:00 PM PDT US researchers report that tamoxifen and toremifene are equivalent, in terms of therapeutic efficacy, for the treatment of hormone receptor-positive breast cancer.

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