Medical News

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• Sputum color may indicate bacterial colonization in COPD
• Nasal eosinophilia indicates airway inflammation in asthma
• COPD patients at increased risk for lung cancer, heart failure, but not MI
• Schizophrenia linked to early developmental delays
• Schizophrenia and bipolar affective disorder show antithetical asymmetry
• Higher PPI dose does not benefit peptic ulcer patients
• Reduced fibrinolysis linked to pediatric DVT risk
• Low triglycerides predict death after noncardioembolic ischemic stroke
• PAD is a ‘strong’ indicator of stroke risk
• E17K substitution in <i>AKT1</i> could indicate favorable prostate cancer course
• Positive surgical margins can predict prostate cancer mortality
• E17K substitution in <i>AKT1</i> could indicate favorable prostate cancer course
• Positive surgical margins can predict prostate cancer mortality
• 70-gene signature test is cost-effective breast cancer prognostic tool
• Low triglycerides predict death after noncardioembolic ischemic stroke
• HDL changes may underpin alcohol’s cardioprotective effect
• Limited health literacy increases risk for hypoglycemia in Type 2 diabetics
• Low creatinine linked to Type 2 diabetes in morbidly obese
• No rise in hyperkalemia rate with increased spironolactone use in UK
• Vernakalant bests amiodarone in AF treatment
• 70-gene signature test is cost-effective breast cancer prognostic tool
• Focal therapy an emerging, promising treatment for low-risk prostate cancer
• Tumor characteristics predict mortality in men with breast cancer
• With or without treatment, prostate cancer is a clinical and economic burden
• Selective bone loss treatment cost-effective for prostate ADT patients
• Simplified cell capture method improves CTC yield
• Mild liver disease linked with risk for high-grade prostate cancer
• HER2 overexpression does not affect breast cancer locoregional recurrence

Sputum color may indicate bacterial colonization in COPD Posted: 20 May 2010 05:00 PM PDT Dark yellow or greenish sputum may indicate bacterial colonization of the airways in patients with chronic obstructive pulmonary disease, research suggests.

Nasal eosinophilia indicates airway inflammation in asthma Posted: 20 May 2010 05:00 PM PDT Nasal eosinophilia is a significant predictor of sputum eosinophilia in asthma, suggesting that nasal eosinophilia can be used to assess airway inflammation in patients with the respiratory condition, say Brazilian researchers.

COPD patients at increased risk for lung cancer, heart failure, but not MI Posted: 20 May 2010 05:00 PM PDT Patients with chronic obstructive pulmonary disease are at increased risk for lung cancer and heart failure, but not myocardial infarction, results from a UK study show.

Schizophrenia linked to early developmental delays Posted: 20 May 2010 05:00 PM PDT Study findings support an association between the risk for schizophrenia and developmental delays as early as the first year of life.

Schizophrenia and bipolar affective disorder show antithetical asymmetry Posted: 20 May 2010 05:00 PM PDT Study findings suggest attenuation of normal pseudoneglect in patients with schizophrenia and accentuation of pseudoneglect in patients with bipolar affective disorder.

Higher PPI dose does not benefit peptic ulcer patients Posted: 20 May 2010 05:00 PM PDT Results from a systematic review and meta-analysis show that high-dose proton pump inhibitors do not reduce rates of rebleeding, surgical intervention, or mortality to a greater extent than non–high-dose PPIs in patients who have had endoscopic treatment for bleeding peptic ulcers.

Reduced fibrinolysis linked to pediatric DVT risk Posted: 19 May 2010 05:00 PM PDT Hypofibrinolysis may play a key role in the development of noncatheter-related deep vein thrombosis in children, study findings suggest.

Low triglycerides predict death after noncardioembolic ischemic stroke Posted: 19 May 2010 05:00 PM PDT Low serum levels of triglycerides independently predict the risk for death after ischemic stroke from noncardioembolic causes, a prospective follow-up study suggests.

PAD is a ‘strong’ indicator of stroke risk Posted: 19 May 2010 05:00 PM PDT Having peripheral artery disease doubles people's risk for stroke, shows a large, observational study.

E17K substitution in <i>AKT1</i> could indicate favorable prostate cancer course Posted: 19 May 2010 05:00 PM PDT Dutch researchers have found a possible link between an amino acid mutation in the v-akt murine thymoma viral oncogene homolog 1 signaling pathway and a favorable clinical course in prostate cancer patients.

Positive surgical margins can predict prostate cancer mortality Posted: 19 May 2010 05:00 PM PDT US study results show that the presence of positive surgical margins after radical prostatectomy is an independent predictor for prostate cancer-specific mortality.

E17K substitution in <i>AKT1</i> could indicate favorable prostate cancer course Posted: 19 May 2010 05:00 PM PDT Dutch researchers have found a possible link between an amino acid mutation in the v-akt murine thymoma viral oncogene homolog 1 signaling pathway and a favorable clinical course in prostate cancer patients.

Positive surgical margins can predict prostate cancer mortality Posted: 19 May 2010 05:00 PM PDT US study results show that the presence of positive surgical margins after radical prostatectomy is an independent predictor for prostate cancer-specific mortality.

70-gene signature test is cost-effective breast cancer prognostic tool Posted: 19 May 2010 05:00 PM PDT The 70-gene signature test improves quality-adjusted survival in patients with breast cancer and has the highest probability of being cost-effective when compared with the Sankt Gallen guidelines and the Adjuvant Online Software, according to Dutch researchers.

Low triglycerides predict death after noncardioembolic ischemic stroke Posted: 19 May 2010 05:00 PM PDT Low serum levels of triglycerides independently predict the risk for death after ischemic stroke from noncardioembolic causes, a prospective follow-up study suggests.

HDL changes may underpin alcohol’s cardioprotective effect Posted: 19 May 2010 05:00 PM PDT The putative cardioprotective effect of moderate alcohol consumption may be mediated by a beneficial effect of alcohol on high-density lipoprotein cholesterol concentration and size, research suggests.

Limited health literacy increases risk for hypoglycemia in Type 2 diabetics Posted: 19 May 2010 05:00 PM PDT Limited health literacy significantly increases the risk for hypoglycemia in patients with Type 2 diabetes, report researchers.

Low creatinine linked to Type 2 diabetes in morbidly obese Posted: 19 May 2010 05:00 PM PDT Low serum creatinine levels independently predict the risk for Type 2 diabetes in morbidly obese Caucasian patients, suggest study results.

No rise in hyperkalemia rate with increased spironolactone use in UK Posted: 19 May 2010 05:00 PM PDT Hospital admissions for hyperkalemia did not rise in Tayside, UK, between 1994 and 2007 despite a marked increase in use of spironolactone in patients with and without heart failure, research shows.

Vernakalant bests amiodarone in AF treatment Posted: 19 May 2010 05:00 PM PDT The novel intravenous anti-arrhythmic drug vernakalant is more effective than amiodarone for rapid conversion of atrial fibrillation to sinus rhythm, results of the AVRO randomized clinical trial show

70-gene signature test is cost-effective breast cancer prognostic tool Posted: 19 May 2010 05:00 PM PDT The 70-gene signature test improves quality-adjusted survival in patients with breast cancer and has the highest probability of being cost-effective when compared with the Sankt Gallen guidelines and the Adjuvant Online Software, according to Dutch researchers.

Focal therapy an emerging, promising treatment for low-risk prostate cancer Posted: 18 May 2010 05:00 PM PDT Focal therapy is a promising and emerging therapy for prostate cancer patients with a low risk for cancer progression or metastasis, show the results of a collaborative review.

Tumor characteristics predict mortality in men with breast cancer Posted: 18 May 2010 05:00 PM PDT Tumor characteristics and marital status are the primary predictors of chemotherapy and cancer mortality among men with breast cancer, US researchers report.

With or without treatment, prostate cancer is a clinical and economic burden Posted: 17 May 2010 05:00 PM PDT The clinical and economic cost of prostate cancer is a significant burden to society, regardless of whether men are receiving active treatment or undergoing watchful waiting, show US study findings.

Selective bone loss treatment cost-effective for prostate ADT patients Posted: 17 May 2010 05:00 PM PDT US study results show that a cost-effective way to address potential bone loss in prostate cancer patients treated with androgen deprivation therapy, is to first identify whether men have osteoporosis using bone mineral density analysis, and then initiate antiresorptive therapy.

Simplified cell capture method improves CTC yield Posted: 17 May 2010 05:00 PM PDT US researchers report a simplified method for capturing circulating tumor cells that results in a significantly improved yield and facilitates molecular characterization and recognition of discordant human epidermal growth factor receptor 2 amplification in breast cancer.

Mild liver disease linked with risk for high-grade prostate cancer Posted: 16 May 2010 05:00 PM PDT US study results indicate an association between mild liver dysfunction and the presence of high-grade prostate cancer in men undergoing radical prostatectomy.

HER2 overexpression does not affect breast cancer locoregional recurrence Posted: 16 May 2010 05:00 PM PDT Human epidermal growth factor receptor (HER)2 overexpression is not associated with an increased risk for local or regional recurrence in women with early stage breast cancer, Canadian researchers report.

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