Medical News

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• Fibroblast proteoglycan production altered in COPD
• Subcutaneous and sublingual immunotherapy bests drugs alone in asthma/rhinitis patients
• Sensitivity to grass pollen linked with asthma epidemics
• Gender differences in brain size and shape altered in bipolar disorder
• Facial expressions of schizophrenia patients ‘poorly understood’
• Body mass index linked to prostate tumor volume
• Lifestyle factors do not influence genetic risk for breast cancer
• Therapeutic rationale for CETP inhibition in doubt
• LDL apheresis lowers apoE4, HDL cholesterol levels
• Lymphocytic esophagitis linked to CD in pediatric patients
• Cardiometabolic risk factors ‘highly prevalent’ in children with Type 1 diabetes
• CCTA imaging useful for predicting future CV events in diabetics
• Timeliness of STEMI reperfusion strongly predicts mortality
• Vascular closure devices, bivalirudin reduce bleeding in PCI

Fibroblast proteoglycan production altered in COPD Posted: 02 Jun 2010 05:00 PM PDT Fibroblasts from individuals with chronic obstructive pulmonary disease have altered proteoglycan production that appears to contribute to disease development, research shows.

Subcutaneous and sublingual immunotherapy bests drugs alone in asthma/rhinitis patients Posted: 02 Jun 2010 05:00 PM PDT Treating house dust mite-sensitized children with asthma or rhinitis with sublingual or subcutaneous immunotherapy is clinically superior to pharmacotherapy alone, research shows.

Sensitivity to grass pollen linked with asthma epidemics Posted: 02 Jun 2010 05:00 PM PDT Exposure to grass pollen is associated with an epidemic increase in asthma episodes during the late spring, a Spanish study suggests.

Gender differences in brain size and shape altered in bipolar disorder Posted: 02 Jun 2010 05:00 PM PDT Normal gender differences in brain volume are increased, while gender differences in asymmetry are decreased, in bipolar disorder patients, indicating an interaction between brain growth and gender in these patients, conclude researchers.

Facial expressions of schizophrenia patients ‘poorly understood’ Posted: 02 Jun 2010 05:00 PM PDT The facial expressions of emotions by patients with schizophrenia are poorly understood by untrained observers, report US investigators in findings that may partly explain impaired social functioning in schizophrenia.

Body mass index linked to prostate tumor volume Posted: 01 Jun 2010 05:00 PM PDT A prostate cancer patient's body mass index is correlated with the size of his tumor, show the results of a US study.

Lifestyle factors do not influence genetic risk for breast cancer Posted: 01 Jun 2010 05:00 PM PDT Lifestyle risk factors such as the use of hormone replacement therapy, and age at birth of first child, do not alter the risk for breast cancer associated with low-penetrance susceptibility polymorphisms, study findings indicate.

Therapeutic rationale for CETP inhibition in doubt Posted: 01 Jun 2010 05:00 PM PDT Low levels of cholesteryl ester transfer protein are associated with an increased risk for death and cardiovascular events in nondiabetic patients with coronary artery disease, an analysis of clinical trial data suggests.

LDL apheresis lowers apoE4, HDL cholesterol levels Posted: 01 Jun 2010 05:00 PM PDT Low-density lipoprotein apheresis reduces plasma levels of apolipoprotein E4, possibly via a selective reduction in high-density lipoprotein cholesterol, US researchers believe.

Lymphocytic esophagitis linked to CD in pediatric patients Posted: 01 Jun 2010 05:00 PM PDT Pediatric lymphocytic esophagitis is a manifestation of pediatric Crohn's disease rather than ulcerative colitis or non-inflammatory bowel disease, suggest study results.

Cardiometabolic risk factors ‘highly prevalent’ in children with Type 1 diabetes Posted: 01 Jun 2010 05:00 PM PDT Results from a Dutch study show that children with Type 1 diabetes have a high prevalence of various cardiometabolic risk factors and the metabolic syndrome.

CCTA imaging useful for predicting future CV events in diabetics Posted: 01 Jun 2010 05:00 PM PDT Coronary computed tomography angiography imaging helps predict cardiovascular event risk in patients with diabetes, but no known coronary artery disease.

Timeliness of STEMI reperfusion strongly predicts mortality Posted: 01 Jun 2010 05:00 PM PDT The timeliness of reperfusion in patients with ST-segment elevation myocardial infarction strongly predicts mortality, irrespective of the reperfusion strategy used, analysis of registry data from Quebec, Canada, shows.

Vascular closure devices, bivalirudin reduce bleeding in PCI Posted: 01 Jun 2010 05:00 PM PDT Use of vascular closure devices and treatment with bivalirudin are associated with reduced bleeding rates among patients undergoing percutaneous coronary intervention, according to an analysis of registry data.

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