Medical News

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• Granulocytes from sputum help identify severe asthma
• Airway smooth muscle remodeling is dynamic in severe asthma
• PI3Kδ expression, signaling increased in lung macrophages of COPD patients
• Cerebrospinal fluid particles linked to bipolar disorder disease processes
• CBT improves depression in psychosis patients
• GERD scoring system developed for diagnosis in resource-poor settings
• Fatal PE symptoms may last weeks in the young
• PUFA ethyl ester supplements alter carotid plaque composition
• Surge in stroke in middle-aged women fuelled by obesity epidemic
• Nanotechnology assay more accurately detects PSA levels after prostate surgery
• Refusal of prostate surgery and alternative treatment reduces long-term survival
• Nanotechnology assay more accurately detects PSA levels after prostate surgery
• Aromatase inhibitors active in men with breast cancer
• Refusal of prostate surgery and alternative treatment reduces long-term survival
• Statins show potent anti-ischemic effect in stable angina
• PUFA ethyl ester supplements alter carotid plaque composition
• Surge in stroke in middle-aged women fuelled by obesity epidemic
• Antipsychotic use increases risk for Type 2 diabetes
• Treating OSA may improve macrovascular outcomes for Type 2 diabetics
• Score predicts non-CABG related bleeding and subsequent mortality in ACS
• Impact of changes in HF management mixed
• Aromatase inhibitors active in men with breast cancer
• Body mass index linked to prostate tumor volume
• Lifestyle factors do not influence genetic risk for breast cancer
• Calcium intake linked to prostate cancer risk among Chinese men
• HIFU for localized prostate cancer has high rate of minor complications
• APBI plus IMRT feasible for breast cancer treatment

Granulocytes from sputum help identify severe asthma Posted: 03 Jun 2010 05:00 PM PDT Inflammatory granulocytes from sputum identify asthma patients with different pathologies and clinical characteristics, US research shows.

Airway smooth muscle remodeling is dynamic in severe asthma Posted: 03 Jun 2010 05:00 PM PDT A sensitive marker of proliferating cells suggests that airway remodeling is a dynamic process in patients with severe asthma, results from a Canadian study show.

PI3Kδ expression, signaling increased in lung macrophages of COPD patients Posted: 03 Jun 2010 05:00 PM PDT Research suggests that impaired glucocorticoid function in the lungs of patients with chronic obstructive pulmonary disease might be caused by increased phosphoinositol 3–kinase δ expression and signaling.

Cerebrospinal fluid particles linked to bipolar disorder disease processes Posted: 03 Jun 2010 05:00 PM PDT Novel particles identified in the first fraction of cerebrospinal fluid (CSF) from bipolar disorder patients may correlate with the degree of underlying disease processes in the central nervous system, suggests a team of Swedish scientists.

CBT improves depression in psychosis patients Posted: 03 Jun 2010 05:00 PM PDT Cognitive behavior therapy delivered in routine clinical practice significantly improves depression in psychosis patients, with smaller improvements for emotional and cognitive variables, the results of a UK study indicate.

GERD scoring system developed for diagnosis in resource-poor settings Posted: 03 Jun 2010 05:00 PM PDT A simple scoring system that assesses both symptom frequency and severity may be effective for diagnosing gastroesophageal reflux disease in resource-poor settings, suggest study findings.

Fatal PE symptoms may last weeks in the young Posted: 02 Jun 2010 05:00 PM PDT Young patients with fatal pulmonary embolism may experience symptoms for weeks or months, but the majority of cases are not identified before death, suggest study findings published in the Journal of Thrombosis and Haemostasis.

PUFA ethyl ester supplements alter carotid plaque composition Posted: 02 Jun 2010 05:00 PM PDT Advanced atherosclerotic plaques appear to readily incorporate eicosapentaenoic acid from supplements containing n-3 polyunsaturated fatty acid ethyl esters, a trial of patients undergoing carotid endarterectomy indicates.

Surge in stroke in middle-aged women fuelled by obesity epidemic Posted: 02 Jun 2010 05:00 PM PDT The recent rise in stroke prevalence among middle-aged US women may be down to the obesity epidemic, say researchers.

Nanotechnology assay more accurately detects PSA levels after prostate surgery Posted: 02 Jun 2010 05:00 PM PDT US researchers have used a nanotechnology-enabled assay to successfully measure otherwise undetectably low prostate-specific antigen levels in post-radical prostatectomy patients.

Refusal of prostate surgery and alternative treatment reduces long-term survival Posted: 02 Jun 2010 05:00 PM PDT Patients who refuse radical prostatectomy for low-risk prostate cancer have better long-term survival if they chose to undergo alternative rather than no treatment, show study results presented at the 2010 American Urology Association's annual meeting in San Francisco, USA, this week.

Nanotechnology assay more accurately detects PSA levels after prostate surgery Posted: 02 Jun 2010 05:00 PM PDT US researchers have used a nanotechnology-enabled assay to successfully measure otherwise undetectably low prostate-specific antigen levels in post-radical prostatectomy patients.

Aromatase inhibitors active in men with breast cancer Posted: 02 Jun 2010 05:00 PM PDT Aromatase inhibition leads to a significant decrease in estradiol levels in men with breast cancer, French researchers report.

Refusal of prostate surgery and alternative treatment reduces long-term survival Posted: 02 Jun 2010 05:00 PM PDT Patients who refuse radical prostatectomy for low-risk prostate cancer have better long-term survival if they chose to undergo alternative rather than no treatment, show study results presented at the 2010 American Urology Association's annual meeting in San Francisco, USA, this week.

Statins show potent anti-ischemic effect in stable angina Posted: 02 Jun 2010 05:00 PM PDT Statins could exert anti-ischemic effects in patients with chronic stable angina that are as potent as those of the calcium-channel blocker amlodipine, trial findings suggest.

PUFA ethyl ester supplements alter carotid plaque composition Posted: 02 Jun 2010 05:00 PM PDT Advanced atherosclerotic plaques appear to readily incorporate eicosapentaenoic acid from supplements containing n-3 polyunsaturated fatty acid ethyl esters, a trial of patients undergoing carotid endarterectomy indicates.

Surge in stroke in middle-aged women fuelled by obesity epidemic Posted: 02 Jun 2010 05:00 PM PDT The recent rise in stroke prevalence among middle-aged US women may be down to the obesity epidemic, say researchers.

Antipsychotic use increases risk for Type 2 diabetes Posted: 02 Jun 2010 05:00 PM PDT Current and initial treatment with the antipsychotic medications olanzapine, clozapine, or mid- and low-potency first-generation antipsychotics, increases the risk for Type 2 diabetes in schizophrenia patients, report researchers.

Treating OSA may improve macrovascular outcomes for Type 2 diabetics Posted: 02 Jun 2010 05:00 PM PDT Obstructive sleep apnea impairs brachial artery endothelial function to a similar degree to Type 2 diabetes, show study results.

Score predicts non-CABG related bleeding and subsequent mortality in ACS Posted: 02 Jun 2010 05:00 PM PDT A simple risk score based on six baseline measures plus anticoagulation regimen can identify patients with acute coronary syndrome who are at high risk for bleeding unrelated to coronary artery bypass graft surgery and subsequent 1-year mortality, report US researchers.

Impact of changes in HF management mixed Posted: 02 Jun 2010 05:00 PM PDT A large observational study in the USA has found that marked changes in the way patients hospitalized with heart failure are managed in recent years may not have resulted in improved patient outcomes in all areas.

Aromatase inhibitors active in men with breast cancer Posted: 02 Jun 2010 05:00 PM PDT Aromatase inhibition leads to a significant decrease in estradiol levels in men with breast cancer, French researchers report.

Body mass index linked to prostate tumor volume Posted: 01 Jun 2010 05:00 PM PDT A prostate cancer patient's body mass index is correlated with the size of his tumor, show the results of a US study.

Lifestyle factors do not influence genetic risk for breast cancer Posted: 01 Jun 2010 05:00 PM PDT Lifestyle risk factors such as the use of hormone replacement therapy, and age at birth of first child, do not alter the risk for breast cancer associated with low-penetrance susceptibility polymorphisms, study findings indicate.

Calcium intake linked to prostate cancer risk among Chinese men Posted: 31 May 2010 05:00 PM PDT Calcium consumption, even at low levels and from non-dairy food sources, increases the risk for developing prostate cancer among Chinese men, researchers report.

HIFU for localized prostate cancer has high rate of minor complications Posted: 31 May 2010 05:00 PM PDT Almost half of men treated with high-intensity focused ultrasound for localized prostate cancer experience complications after treatment, show French study results.

APBI plus IMRT feasible for breast cancer treatment Posted: 31 May 2010 05:00 PM PDT Accelerated partial breast irradiation with intensity-modulated radiotherapy is a feasible treatment for breast cancer, with very low acute toxicity, Italian researchers report.

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