Medical News

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• Long-term LABA monotherapy may increase asthma patients’ hospitalization risk
• Montelukast may reduce efficacy of immunotherapy in children
• Patients with COPD exacerbations at high risk for VTE
• Functional recovery in bipolar disorder linked to marriage, education
• Stress-reactivity is intermediary phenotype for psychosis
• GERD symptoms predict long but not short segment BE
• Global assay predicts recurrent VTE risk
• Low-dose transdermal HRT may avoid stroke risk
• D-dimer may predict outcome in hormone receptor-negative breast cancer
• SNPs identified which could help identify early-onset prostate cancer
• Resistin shows inverse correlation with HDL cholesterol
• Traditional vascular risk factors predict heart-valve calcification
• Vildagliptin effective and well-tolerated add-on to glimepiride
• Markers of fatty liver disease predict incident diabetes
• Allopurinol ‘useful, well-tolerated’ in angina
• Low fitness, physical activity in young adulthood portends hypertension

Long-term LABA monotherapy may increase asthma patients’ hospitalization risk Posted: 08 Jun 2010 05:00 PM PDT Long-term monotherapy with the long-acting beta-2 agonist salmeterol is associated with an increased risk for hospitalization in patients with asthma, whereas its long term use in combination with an inhaled corticosteroid is not, results from a US study suggest.

Montelukast may reduce efficacy of immunotherapy in children Posted: 08 Jun 2010 05:00 PM PDT Treatment with the oral leukotriene receptor antagonist montelukast may reduce the effectiveness of allergen-specific immunotherapy in children with asthma, contrary to expectations, study findings suggest.

Patients with COPD exacerbations at high risk for VTE Posted: 08 Jun 2010 05:00 PM PDT Chronic obstructive pulmonary disease patients who have been hospitalized for an exacerbation are at high risk for venous thromboembolism, results from a Turkish study show.

Functional recovery in bipolar disorder linked to marriage, education Posted: 08 Jun 2010 05:00 PM PDT Less than half of patients with bipolar disorder achieve functional recovery, report researchers who note that married patients, those with greater education, and those with fewer years of illness are more likely to recover.

Stress-reactivity is intermediary phenotype for psychosis Posted: 08 Jun 2010 05:00 PM PDT The siblings of patients with psychosis and severe positive symptoms tend to show increased reactivity to stress compared with the siblings of psychosis patients with mild positive symptoms, study results show.

GERD symptoms predict long but not short segment BE Posted: 08 Jun 2010 05:00 PM PDT Gastroesophageal reflux disease symptoms significantly predict long, but not short, segment Barrett's esophagus, show results from a systematic review and meta-analysis.

Global assay predicts recurrent VTE risk Posted: 07 Jun 2010 05:00 PM PDT A snake venom-based global assay for the protein C anticoagulant pathway may help identify patients at risk for recurrent venous thromboembolism, scientists say.

Low-dose transdermal HRT may avoid stroke risk Posted: 07 Jun 2010 05:00 PM PDT Women taking postmenopausal estrogen may reduce the associated stroke risk by taking the hormone as a low-dose transdermal patch rather than orally, research suggests.

D-dimer may predict outcome in hormone receptor-negative breast cancer Posted: 07 Jun 2010 05:00 PM PDT Brazilian researchers have shown that plasma D-dimer levels are raised in women with hormone receptor-negative breast cancer, particularly in those with a poor short-term outcome.

SNPs identified which could help identify early-onset prostate cancer Posted: 07 Jun 2010 05:00 PM PDT US researchers have found that men diagnosed with early-onset prostate cancer carry more genetic risk alleles for the disease compared with men without the disease, and those diagnosed later in life.

Resistin shows inverse correlation with HDL cholesterol Posted: 07 Jun 2010 05:00 PM PDT Levels of the adipocytokine resistin inversely correlate with high-density lipoprotein cholesterol levels in women, Japanese research shows.

Traditional vascular risk factors predict heart-valve calcification Posted: 07 Jun 2010 05:00 PM PDT Exposure to cardiovascular risk factors in mid-adulthood is associated with heart-valve calcification 30 years later, a new analysis of the Framingham Offspring Study indicates.

Vildagliptin effective and well-tolerated add-on to glimepiride Posted: 07 Jun 2010 05:00 PM PDT Vildagliptin is an effective and well-tolerated add-on therapy to glimepiride for the treatment of patients with Type 2 diabetes, report Japanese researchers.

Markers of fatty liver disease predict incident diabetes Posted: 07 Jun 2010 05:00 PM PDT Study results show that two markers of fatty liver disease, the Fatty Liver Index and the non alcoholic fatty liver disease score, both significantly predict incident Type 2 diabetes.

Allopurinol ‘useful, well-tolerated’ in angina Posted: 07 Jun 2010 05:00 PM PDT Researchers report that the xanthine oxidase inhibitor allopurinol seems to be a useful and well tolerated anti-ischemic treatment for patients with angina.

Low fitness, physical activity in young adulthood portends hypertension Posted: 07 Jun 2010 05:00 PM PDT Low levels of fitness in young adults may account for a substantial proportion of hypertension incidence, researchers report in the journal Hypertension.

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