Medical News

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• Risk for newer OAC drug–drug interactions highlighted
• Warfarin helps prevent stroke during catheter ablation of AF
• Adalimumab may reduce depressive symptoms in patients with psoriasis
• Additional radiotherapy extends survival of hormone-treated prostate patients
• Usefulness of PSA test to identify prostate cancer may be diminishing
• Aromatase inhibitor resistance mechanism identified in breast cancer
• Additional radiotherapy extends survival of hormone-treated prostate patients
• Usefulness of PSA test to identify prostate cancer may be diminishing
• Cognitive performance not linked with statin use
• Novel small molecule increases HDL cholesterol and apoA-1 levels
• <i>IGF2BP2</i> variants influence repaglinide efficacy for treating Type 2 diabetes
• Type 2 diabetes linked to increased risk for genital, digestive cancer in women
• MI admissions in England fell after smoking ban
• Fatal and nonfatal MI rates fell in past decade
• Aromatase inhibitor resistance mechanism identified in breast cancer

Risk for newer OAC drug–drug interactions highlighted Posted: 10 Jun 2010 05:00 PM PDT The risk for interactions between new oral anticoagulant agents and foods, drugs, and dietary supplements has been flagged in a review published in the International Journal of Clinical Practice.

Warfarin helps prevent stroke during catheter ablation of AF Posted: 10 Jun 2010 05:00 PM PDT Continuing warfarin during catheter ablation for atrial fibrillation may help to reduce patients' risk for periprocedural stroke, researchers have found.

Adalimumab may reduce depressive symptoms in patients with psoriasis Posted: 10 Jun 2010 05:00 PM PDT Adalimumab treatment may reduce depression as well as skin symptoms in patients with psoriasis, thereby improving health-related quality of life, say researchers.

Additional radiotherapy extends survival of hormone-treated prostate patients Posted: 10 Jun 2010 05:00 PM PDT Study results show a significant survival benefit for men with locally advanced prostate cancer who receive radiotherapy and androgen deprivation therapy, as opposed to hormone therapy alone.

Usefulness of PSA test to identify prostate cancer may be diminishing Posted: 10 Jun 2010 05:00 PM PDT US study results show that the usefulness of the prostate-specific antigen test as a screening tool for prostate cancer may be diminishing over time.

Aromatase inhibitor resistance mechanism identified in breast cancer Posted: 10 Jun 2010 05:00 PM PDT Phosphatidylinositol-3 kinase plays a key role in the emergence and maintenance of resistance to aromatase inhibitors in breast cancer, US research shows.

Additional radiotherapy extends survival of hormone-treated prostate patients Posted: 10 Jun 2010 05:00 PM PDT Study results show a significant survival benefit for men with locally advanced prostate cancer who receive radiotherapy and androgen deprivation therapy, as opposed to hormone therapy alone.

Usefulness of PSA test to identify prostate cancer may be diminishing Posted: 10 Jun 2010 05:00 PM PDT US study results show that the usefulness of the prostate-specific antigen test as a screening tool for prostate cancer may be diminishing over time.

Cognitive performance not linked with statin use Posted: 10 Jun 2010 05:00 PM PDT A large, cross-sectional study has found no evidence to support an association between statins and cognitive performance.

Novel small molecule increases HDL cholesterol and apoA-1 levels Posted: 10 Jun 2010 05:00 PM PDT A novel small molecule, RVX-208, increases levels of high-density lipoprotein cholesterol and apolipoprotein A-1 in vivo and in vitro, researchers report.

<i>IGF2BP2</i> variants influence repaglinide efficacy for treating Type 2 diabetes Posted: 10 Jun 2010 05:00 PM PDT Study results show that risk alleles of two variants of the insulin-like growth factor 2 mRNA-binding protein 2 gene are present at a higher frequency and reduce the efficacy of repaglinide therapy in Chinese patients with Type 2 diabetes.

Type 2 diabetes linked to increased risk for genital, digestive cancer in women Posted: 10 Jun 2010 05:00 PM PDT Women with Type 2 diabetes have significantly increased risk for genital and digestive cancers compared with their nondiabetic peers, show study results.

MI admissions in England fell after smoking ban Posted: 10 Jun 2010 05:00 PM PDT Myocardial infarction admissions in England, UK, fell by 1200 in the year following the introduction of smoke-free laws, researchers report.

Fatal and nonfatal MI rates fell in past decade Posted: 10 Jun 2010 05:00 PM PDT Researchers have documented reductions in fatal and nonfatal myocardial infarction since 1999 in a large, community-based population in the USA.

Aromatase inhibitor resistance mechanism identified in breast cancer Posted: 10 Jun 2010 05:00 PM PDT Phosphatidylinositol-3 kinase plays a key role in the emergence and maintenance of resistance to aromatase inhibitors in breast cancer, US research shows.

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