Saturday, November 7, 2009

Medical News

Medical News

Coagulation markers predict acute MI outcome

Posted: 05 Nov 2009 04:00 PM PST

Patients with myocardial infarction have higher levels of key coagulation markers at time of hospital admission than healthy individuals, with the highest levels found in patients with a poor outcome, researchers say.

Silent PAD predicts adverse outcome in stroke/TIA patients

Posted: 05 Nov 2009 04:00 PM PST

The presence of asymptomatic peripheral arterial disease in patients with stroke or transient ischemic attack is a major risk factor for recurrent vascular events, a study indicates.

Increased cancer risk may be modified by statins in COPD patients

Posted: 05 Nov 2009 04:00 PM PST

Patients with chronic obstructive pulmonary disease face an increased risk for death from lung cancer and other non-pulmonary malignancies, say researchers who also found that statin therapy may reduce cancer-related mortality among such patients.

Antibiotic use linked to asthma in childhood

Posted: 05 Nov 2009 04:00 PM PST

Antibiotic use in early life is associated with an increased risk for asthma, rhinoconjunctivitis, and eczema in later childhood, study results suggest.

Risk score predicts asthma in preschool children

Posted: 05 Nov 2009 04:00 PM PST

A scoring system based on eight clinical parameters predicts future asthma risk in preschool children, say its developers.

Altered impact of dopamine transporter gene variants in schizophrenia

Posted: 05 Nov 2009 04:00 PM PST

Variations in the dopamine transporter gene ordinarily affect insular, cingulate, and striatal function during an executive task, but the impact on activation is altered in patients with schizophrenia, UK scientists have discovered.

Bipolar offspring show highest risk during adolescence

Posted: 05 Nov 2009 04:00 PM PST

The children of bipolar disorder parents face the highest risk for mood episodes during adolescence, with depression almost always the index episode, the results of a Canadian and Czech study indicate.

Psoriasis not independently linked to ischemic heart disease

Posted: 05 Nov 2009 04:00 PM PST

Psoriasis may not be a clinical risk factor for ischemic heart disease hospitalization, Dutch study findings suggest.

Extra hormone therapy improves survival in radiation-treated prostate cancer patients

Posted: 05 Nov 2009 04:00 PM PST

Adding 4 months of hormone therapy to standard radiotherapy for prostate cancer increases overall patient survival rates, suggest results from the largest phase III randomized trial of its kind.

Lack of knowledge, medical mistrust linked to chemotherapy underuse

Posted: 05 Nov 2009 04:00 PM PST

Knowledge and beliefs about treatment, mistrust of the medical system, older age, and comorbidity are all associated with underuse of adjuvant breast cancer treatment, a US survey has revealed.

Extra hormone therapy improves survival in radiation-treated prostate cancer patients

Posted: 05 Nov 2009 04:00 PM PST

Adding 4 months of hormone therapy to standard radiotherapy for prostate cancer increases overall patient survival rates, suggest results from the largest phase III randomized trial of its kind.

High systemic PFOA and PFOS linked to elevated total cholesterol

Posted: 05 Nov 2009 04:00 PM PST

Individuals with high systemic levels of the man-made chemicals perfluorooctanoic acid and perfluorooctane sulfonate have high total cholesterol levels compared with unexposed individuals, report researchers.

Rotator cuff injury linked to dyslipidemia

Posted: 05 Nov 2009 04:00 PM PST

Patients with rotator cuff tendon tears are more likely to have an adverse lipid profile than controls, report researchers.

Silent PAD predicts adverse outcome in stroke/TIA patients

Posted: 05 Nov 2009 04:00 PM PST

The presence of asymptomatic peripheral arterial disease in patients with stroke or transient ischemic attack is a major risk factor for recurrent vascular events, a study indicates.

Laparoscopic Nissen fundoplication superior for short-segment BE

Posted: 05 Nov 2009 04:00 PM PST

Laparoscopic Nissen fundoplication may be the treatment of choice for patients undergoing surgery for short-segment Barrett's esophagus, says a team of scientists.

FDA to revise prescribing information for exenatide, sitagliptin

Posted: 05 Nov 2009 04:00 PM PST

The US Food and Drug Administration has approved drug label revisions for the GLP-1 agonist exenatide to incorporate information obtained from post-marketing reports of acute renal failure and insufficiency experienced by some patients taking the drug.

Albumin excretion linked with BP in normoalbuminuric diabetic patients

Posted: 05 Nov 2009 04:00 PM PST

Urinary albumin excretion is correlated with blood pressure (BP) and glycemic control in normoalbuminuric patients with Type 2 diabetes, a large study has demonstrated.

Raised alkaline phosphatase linked to increased mortality

Posted: 05 Nov 2009 04:00 PM PST

Raised serum alkaline phosphatase (AlkP) levels are associated with adverse clinical outcomes among survivors of myocardial infarction (MI) and the general US population, study data shows.

On-call duty may increase physicians’ cardiovascular disease risk

Posted: 05 Nov 2009 04:00 PM PST

Physicians have a worsened cardiovascular disease risk profile during 24-hour on-call duty, compared with a normal day shift, study findings indicate.

Silent PAD predicts adverse outcome in stroke/TIA patients

Posted: 05 Nov 2009 04:00 PM PST

The presence of asymptomatic peripheral arterial disease in patients with stroke or transient ischemic attack is a major risk factor for recurrent vascular events, a study indicates.

Lack of knowledge, medical mistrust linked to chemotherapy underuse

Posted: 05 Nov 2009 04:00 PM PST

Knowledge and beliefs about treatment, mistrust of the medical system, older age, and comorbidity are all associated with underuse of adjuvant breast cancer treatment, a US survey has revealed.

rFVIIa lessens bleeding after cardiac surgery

Posted: 05 Nov 2009 04:00 PM PST

Recombinant activated factor VII may be beneficial for treating bleeding after cardiac surgery, preliminary research suggests.

PPIs can be used with thienopyridines

Posted: 05 Nov 2009 04:00 PM PST

Clinicians do not need to avoid concomitant use of proton pump inhibitors during percutaneous coronary intervention surgery in acute coronary syndrome patients receiving clopidogrel or prasugrel, study findings indicate.

Stroke volume variation fails to predict fluid responsiveness in abdominal surgery

Posted: 05 Nov 2009 04:00 PM PST

Measuring stroke volume variation using the FloTrac/Vigileo system does not reliably predict fluid responsiveness in patients undergoing major abdominal surgery, researchers report.

Sugmmadex reverses vecuronium-induced NMB faster than neostigmine

Posted: 05 Nov 2009 04:00 PM PST

Sugammadex provides significantly faster reversal of vecuronium-induced neuromuscular blockade than neostigmine, research results show.

D-dimer levels allow short-term PE risk stratification

Posted: 04 Nov 2009 04:00 PM PST

D-dimer levels can help stratify the short-term risk for mortality in patients with pulmonary embolism, Spanish researchers have found.

Cerebral microbleeds are risk factor for first-ever stroke

Posted: 04 Nov 2009 04:00 PM PST

Cerebral microbleeds are an independent risk factor for the development of symptomatic cerebrovascular disease, Japanese researchers have shown.

Lethal prostate cancer predicted using time of PSA rise

Posted: 04 Nov 2009 04:00 PM PST

Men who experience biochemical failure less than 18 months after treatment for prostate cancer are more likely to develop metastases or die from the disease than men who experience BF after 18 months, study findings suggest.

Socioeconomic status does not impact on negative prostate cancer outcome

Posted: 04 Nov 2009 04:00 PM PST

Age, race, marital status and average household income do not influence prostate cancer outcomes, say researchers whose results conflict with previous studies.

Tamoxifen and raloxifene effect cognitive function equally

Posted: 04 Nov 2009 04:00 PM PST

Tamoxifen and raloxifene are associated with similar patterns of cognitive function in postmenopausal women at increased risk for breast cancer, indicate data from a multicenter study.

Lethal prostate cancer predicted using time of PSA rise

Posted: 04 Nov 2009 04:00 PM PST

Men who experience biochemical failure less than 18 months after treatment for prostate cancer are more likely to develop metastases or die from the disease than men who experience BF after 18 months, study findings suggest.

Socioeconomic status does not impact on negative prostate cancer outcome

Posted: 04 Nov 2009 04:00 PM PST

Age, race, marital status and average household income do not influence prostate cancer outcomes, say researchers whose results conflict with previous studies.

Smoking intensity measurements differ in lipoprotein effect

Posted: 04 Nov 2009 04:00 PM PST

Different measures of smoking intensity appear to have differing impacts on lipoprotein levels, US research suggests.

Nicotinic acid shows potential as atherosclerosis therapeutic agent

Posted: 04 Nov 2009 04:00 PM PST

High-dose, modified-release nicotinic acid can reduce carotid atherosclerosis in statin-treated patients with low levels of high-density lipoprotein cholesterol and evidence of atherosclerosis, trial findings indicate.

Diabetics without dementia have normal age-related cognitive decline

Posted: 04 Nov 2009 04:00 PM PST

Results from a Dutch study show no evidence for accelerated cognitive decline in older patients with Type 2 diabetes who do not have dementia, compared with their nondiabetic contemporaries.

Obesity predicts atherothrombotic risk in patients with diabetes, CAD

Posted: 04 Nov 2009 04:00 PM PST

Body mass index and waist circumference are each independently associated with an increased risk for atherothrombosis in patients with Type 2 diabetes mellitus and coronary artery disease, research suggests.

ROOBY trial finds poorer 1-year outcomes with off- versus on-pump CABG

Posted: 04 Nov 2009 04:00 PM PST

Results of the ROOBY trial show patients undergoing coronary artery bypass graft surgery without cardiopulmonary bypass had worse composite clinical outcomes and poorer graft patency at 1 year than patients who underwent conventional on-pump surgery.

Post-traumatic stress disorder independently linked to poor CV health status

Posted: 04 Nov 2009 04:00 PM PST

US researchers report that post-traumatic stress disorder was associated with significantly worse cardiovascular health status, independently of objective measures of cardiac function and comorbid depression, in a well-characterized cohort of adults with stable CV disease.

Tamoxifen and raloxifene effect cognitive function equally

Posted: 04 Nov 2009 04:00 PM PST

Tamoxifen and raloxifene are associated with similar patterns of cognitive function in postmenopausal women at increased risk for breast cancer, indicate data from a multicenter study.

Accelerated, high-dose radiotherapy as effective as standard prostate cancer treatment

Posted: 03 Nov 2009 04:00 PM PST

A short course of high-dose radiotherapy for prostate cancer is as effective as standard treatment and does not increase the rate of side effects, US researchers report.

pRb loss predicts good outcome in triple negative breast cancer

Posted: 03 Nov 2009 04:00 PM PST

Loss of expression of the retinoblastoma protein is more common in triple-negative breast cancers than in othersubtypes, and is associated with a better outcome after chemotherapy compared with cancers expressing pRb, Italian researchers report.

Prostate cancer recurrence reduced by proton boost to radiation therapy

Posted: 02 Nov 2009 04:00 PM PST

Adding a round of proton therapy to photon radiotherapy reduces cancer recurrence rates in low-risk prostate cancer patients, according to the results of a randomized trial.

AS means long periods without treatment and no worsening of prostate cancer

Posted: 02 Nov 2009 04:00 PM PST

Active surveillance for early prostate cancer could prevent the need for active treatment for up to 2 years with no worsening of the condition, study findings suggest.

Early menopausal hormone therapy may increase breast cancer risk

Posted: 02 Nov 2009 04:00 PM PST

The timing of estrogen-progestagen menopausal hormone therapy initiation transiently modulates the risk for breast cancer, study findings indicate.

FDG-PET/CT useful for initial staging of inflammatory breast cancer patients

Posted: 01 Nov 2009 04:00 PM PST

Eighteen-fluorodeoxyglucose positron emission tomography/computed tomography imaging provides invaluable information regarding nodal status or distant metastases in inflammatory breast cancer patients and should be considered for initial staging, say researchers.
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