Medical News

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• COPD linked to increased carotid wall IMT
• Omalizumab benefits Asian asthma patients
• Prevalence of poorly controlled asthma high in USA
• Psychotic features in bipolar disorder point to worse prognosis
• Benefits of cannabis prevention to avoid schizophrenia ‘unclear’
• Complete endoscopic mucosal resection effective for HGD and BE mucosal cancer
• Novel stroke susceptibility locus identified on chromosome 9q
• Physical activity may reduce prostate cancer incidence
• Physical activity may reduce prostate cancer incidence
• Phosphorylated estrogen receptor-α expression predicts tamoxifen response
• Faxed reminders to physicians do not improve quality of CAD care
• Systemic oxidative stress linked to diabetes, obesity risk factors
• Cystatin C linked to more severe CAD
• Diabetes status affects regulation of cardiac valvular calcification
• Systemic oxidative stress linked to diabetes, obesity risk factors
• Biventricular pacing ‘prevents adverse LV effects of RV apical pacing’
• In-hospital mortality not linked to angioplasty volume in contemporary registry
• Circulating tumor cells linked to increased risk for VTE
• Phosphorylated estrogen receptor-α expression predicts tamoxifen response
• RP feasible for high-risk prostate cancer patients, but they may need additional therapy
• Syndecan-2 protein linked to unfavorable prostate cancer prognosis
• Pregnancy-induced protein may prevent breast cancer
• Outcome favorable for low-risk prostate cancer patients with PSMs after surgery
• Anastrozole plus trastuzumab better than anastrozole alone for certain breast cancers
• Risk for death increased for nonattendees of prostate screening programs
• EBRT plus HDR brachytherapy offers good prostate cancer control and survival rates
• Axillary reverse mapping unsuitable for patients with extensive nodal disease

COPD linked to increased carotid wall IMT Posted: 26 Nov 2009 04:00 PM PST Results from a study in vascular surgery patients show that the presence of chronic obstructive pulmonary disease is associated with increased carotid wall intima-media thickness (IMT), a marker of subclinical atherosclerosis.

Omalizumab benefits Asian asthma patients Posted: 26 Nov 2009 04:00 PM PST Omalizumab improves disease control in Asian patients with moderate-to-severe asthma without causing any significant adverse events, researchers report in findings that are consistent with those from studies conducted in other ethnic groups.

Prevalence of poorly controlled asthma high in USA Posted: 26 Nov 2009 04:00 PM PST More than 40% of US adults with asthma do not have their disease under good control, survey results suggest.

Psychotic features in bipolar disorder point to worse prognosis Posted: 26 Nov 2009 04:00 PM PST Bipolar disorder patients who have psychotic features have a worse prognosis and response to lithium monotherapy than patients without such features, the results of a Turkish study indicate.

Benefits of cannabis prevention to avoid schizophrenia ‘unclear’ Posted: 26 Nov 2009 04:00 PM PST The importance of preventing cannabis use in order to prevent schizophrenia or psychosis cases remains unclear after a UK team found that thousands of heavy users would need to be prevented just to avoid one case.

Complete endoscopic mucosal resection effective for HGD and BE mucosal cancer Posted: 26 Nov 2009 04:00 PM PST Complete Barrett's eradication endoscopic mucosal resection with close endoscopic surveillance is an effective treatment option for patients with Barrett's esophagus with high-grade dysplasia and intramucosal carcinoma, study findings show.

Novel stroke susceptibility locus identified on chromosome 9q Posted: 25 Nov 2009 04:00 PM PST A novel susceptibility locus for stroke has been identified on chromosome 9q, Danish researchers report in the journal Neurology.

Physical activity may reduce prostate cancer incidence Posted: 25 Nov 2009 04:00 PM PST Men who engage in more than 30 minutes of walking or cycling per day during their adult lives may have a reduced risk for developing prostate cancer, say researchers.

Physical activity may reduce prostate cancer incidence Posted: 25 Nov 2009 04:00 PM PST Men who engage in more than 30 minutes of walking or cycling per day during their adult lives may have a reduced risk for developing prostate cancer, say researchers.

Phosphorylated estrogen receptor-α expression predicts tamoxifen response Posted: 25 Nov 2009 04:00 PM PST High expression of a phosphorylated form of estrogen receptor-α is associated with improved recurrence-free survival among tamoxifen-treated, premenopausal women with breast cancer, research shows.

Faxed reminders to physicians do not improve quality of CAD care Posted: 25 Nov 2009 04:00 PM PST Receipt of faxed evidence reminders by primary care physicians does not lead to significant improvements in the quality of care, in particular the use of cholesterol lowering medication, of coronary artery disease patients, show results from a Canadian study.

Systemic oxidative stress linked to diabetes, obesity risk factors Posted: 25 Nov 2009 04:00 PM PST Oxidized low-density lipoprotein is associated with both Type 2 diabetes- and obesity-related traits in Black and White individuals, results from a large prospective study show.

Cystatin C linked to more severe CAD Posted: 25 Nov 2009 04:00 PM PST Study results show that patients with more severe forms of coronary artery disease, such as unstable angina and acute myocardial infarction, have elevated levels of cystatin C.

Diabetes status affects regulation of cardiac valvular calcification Posted: 25 Nov 2009 04:00 PM PST Researchers investigating mechanisms of valvular calcification in patients with stable cardiovascular disease have found that inhibitors of calcification, such as serum uncarboxylated matrix Gla protein, function differently depending on whether or not patients have a diagnosis of diabetes.

Systemic oxidative stress linked to diabetes, obesity risk factors Posted: 25 Nov 2009 04:00 PM PST Oxidized low-density lipoprotein is associated with both Type 2 diabetes- and obesity-related traits in Black and White individuals, results from a large prospective study show.

Biventricular pacing ‘prevents adverse LV effects of RV apical pacing’ Posted: 25 Nov 2009 04:00 PM PST Biventricular pacing can prevent the adverse left ventricular remodeling and reduction in left ventricular ejection fraction observed with conventional right ventricular apical pacing in patients with bradycardia and normal systolic function, researchers report.

In-hospital mortality not linked to angioplasty volume in contemporary registry Posted: 25 Nov 2009 04:00 PM PST An analysis of a registry of patients with ST-segment elevation myocardial infarction shows that treatment at high-volume compared with low-volume angioplasty centers is associated with better door-to-balloon times and greater use of evidence-base medicines.

Circulating tumor cells linked to increased risk for VTE Posted: 25 Nov 2009 04:00 PM PST Patients with metastatic breast cancer and circulating tumor cells should be closely monitored because they have an increased risk for venous thromboembolism, say researchers.

Phosphorylated estrogen receptor-α expression predicts tamoxifen response Posted: 25 Nov 2009 04:00 PM PST High expression of a phosphorylated form of estrogen receptor-α is associated with improved recurrence-free survival among tamoxifen-treated, premenopausal women with breast cancer, research shows.

RP feasible for high-risk prostate cancer patients, but they may need additional therapy Posted: 24 Nov 2009 04:00 PM PST Men who have high-risk prostate cancer, with a Gleason score of 8 or above, can feasibly be treated with radical prostatectomy, however, adjuvant therapy may be necessary, say researchers.

Syndecan-2 protein linked to unfavorable prostate cancer prognosis Posted: 24 Nov 2009 04:00 PM PST Prostate cancer patients who have overexpression of syndecan-2 in their tumor cells have a worse prognosis than patients whose tumor cells have limited or no expression of the protein, study findings show.

Pregnancy-induced protein may prevent breast cancer Posted: 24 Nov 2009 04:00 PM PST A protein induced by pregnancy hormones has shown the ability to inhibit breast cancer growth in experimental models, US researchers report.

Outcome favorable for low-risk prostate cancer patients with PSMs after surgery Posted: 23 Nov 2009 04:00 PM PST Prostate cancer patients with low-risk disease can expect a favorable long-term outcome, even if they have positive surgical margins after radical prostatectomy, say researchers.

Anastrozole plus trastuzumab better than anastrozole alone for certain breast cancers Posted: 23 Nov 2009 04:00 PM PST The addition of trastuzumab to anastrozole significantly improves outcomes for patients with combined human epidermal growth factor receptor 2-positive and hormone receptor-positive metastatic breast cancer compared with anastrozole alone, study results show.

Risk for death increased for nonattendees of prostate screening programs Posted: 22 Nov 2009 04:00 PM PST Men who are part of a prostate cancer screening program but who do not attend appointments are more likely to die from the disease or from other causes, than men who do attend, report researchers.

EBRT plus HDR brachytherapy offers good prostate cancer control and survival rates Posted: 22 Nov 2009 04:00 PM PST Prostate cancer patients experience longer biochemical disease free and overall survival if they receive external beam radiotherapy combined with high-dose rate brachytherapy, according to a systematic review.

Axillary reverse mapping unsuitable for patients with extensive nodal disease Posted: 22 Nov 2009 04:00 PM PST Extensive nodal disease may impair axillary reverse mapping in patients with breast cancer, Italian researchers report.

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