Medical News

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• Novel susceptibility gene for asthma discovered
• Rituximab treatment for RA reduces influenza vaccine response
• Pediatric deaths raised ten-fold by 2009 H1N1 influenza pandemic
• Low cholesterol levels linked to manic symptomatology in BD
• Food preference judgments intact in schizophrenia
• Smoking and NSAIDs modify risk for esophageal cancers in GER patients
• Intrathecal fentanyl or sufentanil enhance low-dose bupivacaine spinal block
• High peri-operative oxygen fraction does not reduce surgical site infections
• Endoscopist-directed administration of propofol shows good safety profile
• Cuffed TTs do not increase post-extubation stridor risk in small children
• Postoperative VTE risk in women defined
• Rosuvastatin demonstrates efficacy in primary stroke prevention
• Diabetics have increased risk for pulmonary conditions, but not lung cancer
• Subjective emotions linked to function in schizophrenia patients
• 5-HT2 receptor density reduced during manic episodes
• Brachytherapy – feasible for young prostate cancer patients
• Eggs, skin-on poultry increase prostate cancer progression risk
• Brachytherapy – feasible for young prostate cancer patients
• Tumor-associated lymphocytes predict neoadjuvant chemotherapy response
• Eggs, skin-on poultry increase prostate cancer progression risk
• LDL homogenous assays differ in ability to reflect CHD database measurements
• Chylomicrons ‘proatherogenic in mice’
• Rosuvastatin demonstrates efficacy in primary stroke prevention
• HbA1c in diabetes patients fluctuates with seasons
• Diabetics have increased risk for pulmonary conditions, but not lung cancer
• Prasugrel ‘economically attractive’ versus clopidogrel in ACS
• Orthostatic hypotension independent predictor of coronary events
• Rosuvastatin demonstrates efficacy in primary stroke prevention
• Tumor-associated lymphocytes predict neoadjuvant chemotherapy response
• Patient characteristics determine most accurate prostate biopsy protocol
• Bilateral oophorectomy recommended for breast cancer ovarian metastases
• BMI, age, and comorbidity predict non-prostate cancer-specific death after treatment
• Late rectal toxicity after prostate radiation- a ‘dynamic process’
• Adjuvant therapy may not be justified for tubular carcinoma
• PSA screening may be unnecessary in certain men over 75 years
• Pegylated liposomal doxorubicin effective after prior anthracycline exposure

Novel susceptibility gene for asthma discovered Posted: 07 Jan 2010 04:00 PM PST Susceptibility to asthma appears to be associated with a locus on chromosome 1q31.3 that contains a gene expressed by natural killer cells and dendritic cells, results of an international study suggest.

Rituximab treatment for RA reduces influenza vaccine response Posted: 07 Jan 2010 04:00 PM PST Rheumatoid arthritis patients treated with rituximab have reduced humoral responses to the influenza vaccine in the first 6–10 months following administration, conclude Dutch researchers.

Pediatric deaths raised ten-fold by 2009 H1N1 influenza pandemic Posted: 07 Jan 2010 04:00 PM PST The 2009 H1N1 influenza pandemic caused 10 times the number of pediatric deaths than would have been expected from seasonal influenza in previous years, US investigators have discovered.

Low cholesterol levels linked to manic symptomatology in BD Posted: 07 Jan 2010 04:00 PM PST Individuals with bipolar disorder who have low cholesterol levels may be predisposed to a greater burden of manic symptomatology than those with normal or high cholesterol levels, show study findings.

Food preference judgments intact in schizophrenia Posted: 07 Jan 2010 04:00 PM PST US researchers believe that schizophrenia patients have intact food preference judgments but show an alteration in the hedonic values attached to food, which may be related to particular facets of anhedonia.

Smoking and NSAIDs modify risk for esophageal cancers in GER patients Posted: 07 Jan 2010 04:00 PM PST The increased risk for esophageal cancers in patients with frequent gastroesophageal reflux may be exacerbated among smokers, say researchers.

Intrathecal fentanyl or sufentanil enhance low-dose bupivacaine spinal block Posted: 07 Jan 2010 04:00 PM PST The addition of fentanyl or sufentanil to low-dose diluted bupivacaine provides adequate anesthesia without hemodynamic instability for elderly men undergoing transurethral resection of the prostate, research shows.

High peri-operative oxygen fraction does not reduce surgical site infections Posted: 07 Jan 2010 04:00 PM PST Peri-operative administration of 80% oxygen compared with 30% oxygen does not reduce the risk for surgical site infection after abdominal surgery, study results show.

Endoscopist-directed administration of propofol shows good safety profile Posted: 07 Jan 2010 04:00 PM PST Researchers suggest that propofol can be effectively administered by endoscopists for gastrointestinal endoscopy.

Cuffed TTs do not increase post-extubation stridor risk in small children Posted: 07 Jan 2010 04:00 PM PST It is feasible to use cuffed tracheal tubes in small children, say researchers who found their use did not increase the incidence of post-extubation stridor compared with uncuffed TTs.

Postoperative VTE risk in women defined Posted: 06 Jan 2010 04:00 PM PST The risk for postoperative venous thromboembolism in UK middle-aged women has been clarified using data from the Million Women Study.

Rosuvastatin demonstrates efficacy in primary stroke prevention Posted: 06 Jan 2010 04:00 PM PST Rosuvastatin treatment halves the incidence of ischemic stroke in people with normal lipid levels but elevated levels of C-reactive protein, a subanalysis of the JUPITER trial reveals.

Diabetics have increased risk for pulmonary conditions, but not lung cancer Posted: 06 Jan 2010 04:00 PM PST Patients with diabetes are at increased risk for various pulmonary conditions, but not lung cancer, report researchers

Subjective emotions linked to function in schizophrenia patients Posted: 06 Jan 2010 04:00 PM PST Subjective emotional experience can be assessed reliably in patients with schizophrenia and plays a significant part in functional outcomes, the results of a US study indicate.

5-HT2 receptor density reduced during manic episodes Posted: 06 Jan 2010 04:00 PM PST Individuals experiencing a mania episode have reductions in 5-hydroxytryptamine2 receptor density in the brain compared with healthy individuals, conclude researchers.

Brachytherapy – feasible for young prostate cancer patients Posted: 06 Jan 2010 04:00 PM PST Prostate cancer patients aged 55 years or under have excellent biochemical recurrence rates and low toxicity after being treated with 125iodine brachytherapy, study findings demonstrate.

Eggs, skin-on poultry increase prostate cancer progression risk Posted: 06 Jan 2010 04:00 PM PST Consuming a relatively large amount of eggs and poultry with the skin left on may increase prostate cancer patients' chances of experiencing a relapse, study findings indicate.

Brachytherapy – feasible for young prostate cancer patients Posted: 06 Jan 2010 04:00 PM PST Prostate cancer patients aged 55 years or under have excellent biochemical recurrence rates and low toxicity after being treated with 125iodine brachytherapy, study findings demonstrate.

Tumor-associated lymphocytes predict neoadjuvant chemotherapy response Posted: 06 Jan 2010 04:00 PM PST The presence of tumor-associated lymphocytes in breast cancer is independently associated with an improved response to neoadjuvant chemotherapy, German researchers report.

Eggs, skin-on poultry increase prostate cancer progression risk Posted: 06 Jan 2010 04:00 PM PST Consuming a relatively large amount of eggs and poultry with the skin left on may increase prostate cancer patients' chances of experiencing a relapse, study findings indicate.

LDL homogenous assays differ in ability to reflect CHD database measurements Posted: 06 Jan 2010 04:00 PM PST Homogenous assays differ in their ability to reflect low-density lipoprotein cholesterol measurements made in databases for coronary heart disease, research suggests.

Chylomicrons ‘proatherogenic in mice’ Posted: 06 Jan 2010 04:00 PM PST Chylomicronemia causes atherosclerosis in mice, shows a study published this month in the journal Arteriosclerosis, Thrombosis, and Vascular Biology.

Rosuvastatin demonstrates efficacy in primary stroke prevention Posted: 06 Jan 2010 04:00 PM PST Rosuvastatin treatment halves the incidence of ischemic stroke in people with normal lipid levels but elevated levels of C-reactive protein, a subanalysis of the JUPITER trial reveals.

HbA1c in diabetes patients fluctuates with seasons Posted: 06 Jan 2010 04:00 PM PST Glycated hemoglobin levels in diabetes patients may vary according to the season, suggest results from a Japanese study

Diabetics have increased risk for pulmonary conditions, but not lung cancer Posted: 06 Jan 2010 04:00 PM PST Patients with diabetes are at increased risk for various pulmonary conditions, but not lung cancer, report researchers

Prasugrel ‘economically attractive’ versus clopidogrel in ACS Posted: 06 Jan 2010 04:00 PM PST Prasugrel is associated with lower costs and greater life expectancy compared with clopidogrel in the management of patients with acute coronary syndrome, according to the findings of a prespecified US economic analysis of the TRITON-TIMI 38 study.

Orthostatic hypotension independent predictor of coronary events Posted: 06 Jan 2010 04:00 PM PST Study findings show that orthostatic hypotension in middle age is associated with an increased risk for coronary events, independently of traditional coronary heart disease risk factors.

Rosuvastatin demonstrates efficacy in primary stroke prevention Posted: 06 Jan 2010 04:00 PM PST Rosuvastatin treatment halves the incidence of ischemic stroke in people with normal lipid levels but elevated levels of C-reactive protein, a subanalysis of the JUPITER trial reveals.

Tumor-associated lymphocytes predict neoadjuvant chemotherapy response Posted: 06 Jan 2010 04:00 PM PST The presence of tumor-associated lymphocytes in breast cancer is independently associated with an improved response to neoadjuvant chemotherapy, German researchers report.

Patient characteristics determine most accurate prostate biopsy protocol Posted: 05 Jan 2010 04:00 PM PST The individual clinical characteristics of men with suspected prostate cancer determine the most advantageous prostate biopsy protocol, according to research.

Bilateral oophorectomy recommended for breast cancer ovarian metastases Posted: 05 Jan 2010 04:00 PM PST A French study of women with breast cancer who had ovarian metastases has revealed that macroscopic optimal resection improves survival compared with other non-optimal surgical techniques.

BMI, age, and comorbidity predict non-prostate cancer-specific death after treatment Posted: 04 Jan 2010 04:00 PM PST Obesity, old age, and having moderate-to-severe comorbidities are all associated with non-prostate cancer-specific death in men who experience a prostate-specific antigen recurrence after radiotherapy, report US researchers.

Late rectal toxicity after prostate radiation- a ‘dynamic process’ Posted: 04 Jan 2010 04:00 PM PST The development of late rectal toxicity after radiotherapy for prostate cancer is a "dynamic process," with different time courses for rectal bleeding and fecal incontinence, study findings show.

Adjuvant therapy may not be justified for tubular carcinoma Posted: 04 Jan 2010 04:00 PM PST Patients with tubular carcinoma of the breast have a better prognosis than those with grade 1 ductal carcinoma and may not require adjuvant chemotherapy, UK research shows.

PSA screening may be unnecessary in certain men over 75 years Posted: 03 Jan 2010 04:00 PM PST Prostate-specific antigen screening may be feasibly discontinued in African–American and Caucasian American men aged between 75 and 80 years whose initial PSA levels are less than 6 ng/ml and 3 ng/ml, respectively, report researchers.

Pegylated liposomal doxorubicin effective after prior anthracycline exposure Posted: 03 Jan 2010 04:00 PM PST Pegylated liposomal doxorubicin plus cyclophosphamide is effective and well-tolerated in patients with metastatic breast cancer who have received prior adjuvant anthracycline-containing chemotherapy, Canadian researchers report.

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