Medical News

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• No fall in ICH rate over past 2 decades
• ‘Non-usual’ pathogens linked to frequent hospitalization in COPD patients
• Heliox does not benefit patients with acute asthma attacks
• Poorly-controlled childhood asthma common despite consistent ICS use
• Fibroblasts from schizophrenia patients show cell cycle abnormalities
• Bipolar II disorder patients at ‘marked’ risk for suicide attempt
• H. pylori infection linked to autoimmune gastritis
• Warfarin use in post-ACS AF reduces 6-month mortality, MI
• Positive surgical margins after RP do not predict prostate cancer-specific mortality
• <i>BRCA</i> screening should be offered to Jewish women
• Positive surgical margins after RP do not predict prostate cancer-specific mortality
• Italian scientists offer explanation for statin antioxidant effects
• Moderate fatty fish intake reduces ACS risk
• Early invasive strategy beneficial in diabetes patients with AMI
• Very low HbA1c values may be as harmful as very high values
• TIMI score predicts outcome in emergency-setting ACS
• Serial NT-proBNP measures give dynamic HF risk prediction in elderly
• <i>BRCA</i> screening should be offered to Jewish women
• Red and processed meat may increase prostate cancer risk
• PSA-targeted vaccine lengthens survival of advanced prostate cancer patients
• DCIS size underestimated in third of cases
• Type of prostate cancer treatment depends on treatment center
• <i>BRCA1</i> carriers may gain most benefit from platinum-based neoadjuvant chemotherapy
• Continence after LRP recovered more slowly in diabetic prostate cancer patients
• Prostate cancer diagnosis and management equal for Black and White men in UK
• Platinum-based neoadjuvant chemotherapy may be best for <i>BRCA1</i> carriers

No fall in ICH rate over past 2 decades Posted: 28 Jan 2010 04:00 PM PST The incidence of intracerebral hemorrhage has not fallen over the past 20 years, show results of a meta-analysis published in The Lancet Neurology.

‘Non-usual’ pathogens linked to frequent hospitalization in COPD patients Posted: 28 Jan 2010 04:00 PM PST Airway infection with "non-usual" pathogens is the main factor associated with frequent hospitalization in patients with chronic obstructive pulmonary disease, research shows.

Heliox does not benefit patients with acute asthma attacks Posted: 28 Jan 2010 04:00 PM PST Results of a systematic review do not support the routine use of heliox in the treatment of patients suffering from acute asthma attacks.

Poorly-controlled childhood asthma common despite consistent ICS use Posted: 28 Jan 2010 04:00 PM PST Many children with mild-to-moderate asthma do not achieve good control of their disease despite consistent use of inhaled corticosteroids, researchers have found.

Fibroblasts from schizophrenia patients show cell cycle abnormalities Posted: 28 Jan 2010 04:00 PM PST Researchers have identified alterations in cellular proliferation and growth pathways in the fibroblasts of schizophrenia patients.

Bipolar II disorder patients at ‘marked’ risk for suicide attempt Posted: 28 Jan 2010 04:00 PM PST Patients with bipolar II disorder are as likely as those with bipolar I disorder to attempt suicide, study findings show.

H. pylori infection linked to autoimmune gastritis Posted: 28 Jan 2010 04:00 PM PST Study findings suggest that atrophic corpus gastritis, including autoimmune type severe atrophy with vitamin B12 malabsorption, is associated with longstanding Helicobacter pylori infection.

Warfarin use in post-ACS AF reduces 6-month mortality, MI Posted: 27 Jan 2010 04:00 PM PST Warfarin use at discharge from hospital improves short-term outcomes in patients with atrial fibrillation complicated by acute coronary syndromes, suggest study findings.

Positive surgical margins after RP do not predict prostate cancer-specific mortality Posted: 27 Jan 2010 04:00 PM PST The presence of positive surgical margins after radical prostatectomy does not indicate an increased risk for cancer-specific mortality, systemic disease progression, or overall mortality in prostate cancer patients, report researchers.

<i>BRCA</i> screening should be offered to Jewish women Posted: 27 Jan 2010 04:00 PM PST More than half of Jewish women carrying a BRCA1 or BRCA2 mutation would be ineligible for screening under current guidelines, a study in Ontario, Canada has shown.

Positive surgical margins after RP do not predict prostate cancer-specific mortality Posted: 27 Jan 2010 04:00 PM PST The presence of positive surgical margins after radical prostatectomy does not indicate an increased risk for cancer-specific mortality, systemic disease progression, or overall mortality in prostate cancer patients, report researchers.

Italian scientists offer explanation for statin antioxidant effects Posted: 27 Jan 2010 04:00 PM PST Scientists in Italy suggest that the beneficial effects of statins on atherosclerosis and cardiovascular disease risk are linked to pleiotropic actions beyond lowering of lipid levels.

Moderate fatty fish intake reduces ACS risk Posted: 27 Jan 2010 04:00 PM PST A moderate intake of fatty fish reduces the risk for acute coronary syndromes in middle-aged men, although effects in women are unclear, new study findings show.

Early invasive strategy beneficial in diabetes patients with AMI Posted: 27 Jan 2010 04:00 PM PST Patients with diabetes who suffer acute myocardial infarction benefit from acute revascularization and modern pharmacotherapy, Japanese scientists believe.

Very low HbA1c values may be as harmful as very high values Posted: 27 Jan 2010 04:00 PM PST There is a U-shaped relationship between glycated hemoglobin levels and mortality in people with diabetes, say researchers, meaning that intensive glucose-lowering therapy could be as harmful as uncontrolled hyperglycemia.

TIMI score predicts outcome in emergency-setting ACS Posted: 27 Jan 2010 04:00 PM PST Thrombolysis in Myocardial Infarction score in patients presenting to an emergency department with suspected acute coronary syndrome can predict cardiovascular events at 1-year follow-up, study results show.

Serial NT-proBNP measures give dynamic HF risk prediction in elderly Posted: 27 Jan 2010 04:00 PM PST Assessment of N-terminal pro–B-type natriuretic peptide predicts new-onset heart failure and cardiovascular death, independent of traditional factors, in community-dwelling elderly people, research shows.

<i>BRCA</i> screening should be offered to Jewish women Posted: 27 Jan 2010 04:00 PM PST More than half of Jewish women carrying a BRCA1 or BRCA2 mutation would be ineligible for screening under current guidelines, a study in Ontario, Canada has shown.

Red and processed meat may increase prostate cancer risk Posted: 26 Jan 2010 04:00 PM PST Consumption of red and processed meat is associated with an increased risk for total and advanced prostate cancer, study results indicate.

PSA-targeted vaccine lengthens survival of advanced prostate cancer patients Posted: 26 Jan 2010 04:00 PM PST A prostate-specific antigen-targeted poxviral vaccine for prostate cancer could reduce deaths among men with metastatic castration-resistant prostate cancer by 44%, report researchers.

DCIS size underestimated in third of cases Posted: 26 Jan 2010 04:00 PM PST UK study results show that pre-operative imaging underestimates the extent of disease in a third of patients undergoing breast-conserving surgery for ductal carcinoma in situ, resulting in a need for further surgery in these patients.

Type of prostate cancer treatment depends on treatment center Posted: 25 Jan 2010 04:00 PM PST Prostate cancer patients in the USA treated at county hospitals are significantly more likely to undergo surgery than those treated at private hospitals, study findings show.

<i>BRCA1</i> carriers may gain most benefit from platinum-based neoadjuvant chemotherapy Posted: 25 Jan 2010 04:00 PM PST Neoadjuvant chemotherapy with cisplatin is associated with a high rate of pathologic complete response among BRCA1 mutation carriers, a study of Polish women with breast cancer has shown.

Continence after LRP recovered more slowly in diabetic prostate cancer patients Posted: 24 Jan 2010 04:00 PM PST Men with Type 2 diabetes mellitus need longer to recover continence after laparoscopic radical prostatectomy than their non-diabetic counterparts, report researchers.

Prostate cancer diagnosis and management equal for Black and White men in UK Posted: 24 Jan 2010 04:00 PM PST Results of a UK-based study have shown no evidence of differences in prostate cancer characteristics at diagnosis or disease management between Black men and White men.

Platinum-based neoadjuvant chemotherapy may be best for <i>BRCA1</i> carriers Posted: 24 Jan 2010 04:00 PM PST Neoadjuvant chemotherapy with cisplatin is associated with a high rate of pathologic complete response among BRCA1 mutation carriers, a study of Polish women with breast cancer has shown.

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