Medical News

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• Airway hydration linked to neutrophilic inflammation in stable asthma
• Increased air pollution linked to uncontrolled asthma
• Diabetes patients at increased risk for pulmonary disorders
• Antidepressant, antipsychotic polypharmacy on the rise
• Frontline care staff training effective for BD relapse prevention
• Familial aggregation and antimicrobial response have cumulative effect on CD
• PESI best predictor for PE outpatient mortality risk
• Stroke rates in Iran ‘twice as high as in Western countries’
• Researchers link genetic variant to aggressive prostate cancer
• Familial breast cancer occurs earlier than non-familial cancer
• Retraining eating behavior is effective for weight loss in obese adolescents
• Obesity increases adverse cardiovascular markers in children
• Dutogliptin shows preliminary efficacy in Type 2 diabetes
• Roux-en-Y gastric bypass surgery reduces Type 2 diabetes symptoms in severely obese
• Genetic variants influencing heart rate, ECG measures identified
• Physical activity blunts risk from elevated heart rate in women

Airway hydration linked to neutrophilic inflammation in stable asthma Posted: 12 Jan 2010 04:00 PM PST There is a significant association between airway hydration and neutrophilic, but not allergic, inflammation in patients with stable asthma, US researchers have found.

Increased air pollution linked to uncontrolled asthma Posted: 12 Jan 2010 04:00 PM PST Asthma patients who live in areas with high levels of air pollution are more likely to have uncontrolled asthma than those who live in less polluted areas, US research shows.

Diabetes patients at increased risk for pulmonary disorders Posted: 12 Jan 2010 04:00 PM PST Patients with diabetes are at increased risk for asthma, chronic obstructive pulmonary disease, and other lung conditions compared with nondiabetics, research shows.

Antidepressant, antipsychotic polypharmacy on the rise Posted: 12 Jan 2010 04:00 PM PST Polypharmacy involving antidepressant and antipsychotic medications has increased significantly since the mid-1990s, with many of these combinations not supported by data from clinical trials, say US researchers.

Frontline care staff training effective for BD relapse prevention Posted: 12 Jan 2010 04:00 PM PST Training community mental health teams to offer enhanced relapse prevention for bipolar disorder increases the time to recurrence of an episode and improves occupational functioning, suggest UK study findings.

Familial aggregation and antimicrobial response have cumulative effect on CD Posted: 12 Jan 2010 04:00 PM PST Familial aggregation and antimicrobial response dose-dependently affect the risk for Crohn's disease in multicase families, study findings show.

PESI best predictor for PE outpatient mortality risk Posted: 11 Jan 2010 04:00 PM PST The Pulmonary Embolism Severity Index is more accurate at identifying patients suitable for outpatient treatment than levels of troponin I, research suggests.

Stroke rates in Iran ‘twice as high as in Western countries’ Posted: 11 Jan 2010 04:00 PM PST Stroke incidence in Iran is twice as high, and the average age at first stroke 10 years lower, than in many other regions of the world, study findings show.

Researchers link genetic variant to aggressive prostate cancer Posted: 11 Jan 2010 04:00 PM PST Genetic variants predisposing men to aggressive rather than indolent prostate cancer exist in the genome, report researchers.

Familial breast cancer occurs earlier than non-familial cancer Posted: 11 Jan 2010 04:00 PM PST Women with a mother or sister affected by breast cancer are diagnosed with, and die from, breast cancer at an earlier age than women without a family history of breast cancer, a study of Swedish women shows.

Retraining eating behavior is effective for weight loss in obese adolescents Posted: 11 Jan 2010 04:00 PM PST Reducing the speed of eating and amount eaten at meals may help to significantly reduce weight in obese adolescents, show results from a study that trialed a portable computerized device called a Mandometer.

Obesity increases adverse cardiovascular markers in children Posted: 11 Jan 2010 04:00 PM PST Childhood obesity is associated with a proinflammatory and prothrombotic state in the absence of other metabolic syndrome factors and before puberty, report US researchers.

Dutogliptin shows preliminary efficacy in Type 2 diabetes Posted: 11 Jan 2010 04:00 PM PST Dutogliptin treatment improves glycemic control in patients with Type 2 diabetes who are poorly controlled on metformin and/or a thiazolidinedione, a randomized, placebo-controlled trial has shown.

Roux-en-Y gastric bypass surgery reduces Type 2 diabetes symptoms in severely obese Posted: 11 Jan 2010 04:00 PM PST Severely obese patients who undergo Roux-en-Y gastric bypass surgery have significantly improved insulin sensitivity and beta cell responsiveness to glucose compared with those who have gastric restrictive surgery, show study results.

Genetic variants influencing heart rate, ECG measures identified Posted: 11 Jan 2010 04:00 PM PST Three independent studies published in the journal Nature Genetics report on genetic factors influencing heart rate and electrocardiographic measurements.

Physical activity blunts risk from elevated heart rate in women Posted: 11 Jan 2010 04:00 PM PST A higher resting heart rate is particularly strongly associated with increased risk for ischemic heart disease death in women under the age of 70 years, shows a large study.

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