Medical News

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• Combined visual analog scale validated in allergic rhinitis
• Abnormal SERCA2 pump contributes to asthmatic phenotype
• Oseltamivir poses little risk in pregnant women treated for influenza H1N1
• ECT response quicker in bipolar versus unipolar depression
• Lithium serum levels and mood state affect ADRs in bipolar disorder
• Women with bowel disease at increased risk of heart attacks and strokes
• Lung disease patients may benefit from expert-led education programmes
• Green tea compound may slow prostate cancer growth
• Poor flu vaccination rates among adult asthmatics
• FV Leiden does not affect D-dimer concentration, thrombin generation
• ‘Greater efforts needed’ to minimize stroke surgery delays
• Age influences axillary lymph node involvemen in breast cancer patients
• Pure ductal prostate cancer ‘distinct clinical entity’
• Sarcoma watch recommended for breast cancer patients
• Tubal sterilization through electrocoagulation adversely affects ovarian reserve
• Sperm plays a bigger role in embryo development than previously thought
• Progesterone treatment fails to reduce early preterm birth in twin pregnancies
• Pregnant women who snore have increased risk for gestational diabetes
• High incidence of climacteric symptoms, osteoporosis following surgical menopause
• Twice-weekly conjugated estrogen cream effective for atrophic vaginitis
• uVIN-related vulvar SCC increases risk for cervical (pre)malignancies
• Ethnic inequalities exist in the uptake of cervical cancer screening
• Letrozole plus progesterone increases clinical pregnancy rates in PCOS
• Simple physician advice, follow-up sufficient for obese PCOS women to lose weight
• Proteomic analysis of HDL subpopulations reveals particle-specific protein clusters
• <i>APOA5</i> variant influences benefit obtained from statin therapy
• Leadless pacing ‘feasible’ in heart failure
• CRP may not be independent risk factor for Type 2 diabetes
• Carotid IMT predicts cardiovascular risk in patients with Type 2 diabetes
• Leadless pacing ‘feasible’ in heart failure
• Coronary stenoses absent calcification linked to unstable symptoms

Combined visual analog scale validated in allergic rhinitis Posted: 22 Jun 2009 05:00 PM PDT Researchers have shown that a single combined visual analog scale (VAS) can simply and accurately measure treatment efficacy in patients with allergic rhinitis.

Abnormal SERCA2 pump contributes to asthmatic phenotype Posted: 22 Jun 2009 05:00 PM PDT Deficiencies in the sarcoplasmic/endoplasmic reticulum calcium pump contribute to the enhanced proliferation and secretion of proinflammatory cytokines in asthma, research shows.

Oseltamivir poses little risk in pregnant women treated for influenza H1N1 Posted: 22 Jun 2009 05:00 PM PDT It is acceptable for pregnant women requiring treatment for the novel influenza A H1N1 virus to be treated treated with oseltamivir, research shows.

ECT response quicker in bipolar versus unipolar depression Posted: 22 Jun 2009 05:00 PM PDT There are no outcome differences from ultra-brief pulse electroconvulsive therapy (ECT) between bipolar disorder and unipolar depression patients, but the former have a faster response, Belgian study findings suggest.

Lithium serum levels and mood state affect ADRs in bipolar disorder Posted: 22 Jun 2009 05:00 PM PDT Patient reporting and severity of adverse drug reactions (ADRs) during long-term lithium treatment for bipolar disorder are affected by both serum lithium concentration and mood state, say Dutch researchers

Women with bowel disease at increased risk of heart attacks and strokes Posted: 21 Jun 2009 05:00 PM PDT Women with inflammatory bowel disease may be at increased risk of heart attacks and stokes caused by blood clots in arteries, results of a US study suggest.

Lung disease patients may benefit from expert-led education programmes Posted: 21 Jun 2009 05:00 PM PDT Many patients with chronic obstructive pulmonary disease lack knowledge about their condition and would benefit from education programmes led by lung specialists, say researchers.

Green tea compound may slow prostate cancer growth Posted: 21 Jun 2009 05:00 PM PDT A substance found in green tea may help slow the growth of prostate cancer, results of a US study suggest.

Poor flu vaccination rates among adult asthmatics Posted: 21 Jun 2009 05:00 PM PDT Greater efforts are needed to ensure that more adults with asthma receive flu shots, say researchers who found that flu vaccination rates are low among this high-risk group.

FV Leiden does not affect D-dimer concentration, thrombin generation Posted: 21 Jun 2009 05:00 PM PDT A study of patients with suspected venous thromboembolism has revealed that neither D-dimer concentration nor thrombin generation depend on the factor V Leiden mutation.

‘Greater efforts needed’ to minimize stroke surgery delays Posted: 21 Jun 2009 05:00 PM PDT Carotid endarterectomy is not being performed as urgently as guidelines recommend in the majority of patients with stroke or transient ischemic attack, a study of designated stroke centers in Ontario, Canada has shown.

Age influences axillary lymph node involvemen in breast cancer patients Posted: 21 Jun 2009 05:00 PM PDT The chances of axillary lymph node involvement in women with breast cancer decrease with increasing age up to around 70 years, after which the risk increases, a Belgian analysis shows.

Pure ductal prostate cancer ‘distinct clinical entity’ Posted: 21 Jun 2009 05:00 PM PDT Pure ductal prostate adenocarcinoma typically has an indolent clinical course and increased risk for local recurrence, although better post-surgery outcomes, compared with mixed disease, conclude US researchers.

Sarcoma watch recommended for breast cancer patients Posted: 21 Jun 2009 05:00 PM PDT Women with breast cancer who receive radiotherapy or partial mastectomy should receive check-ups for at least 20 years, recommend US researchers on finding these patients have an increased risk for soft tissue sarcomas.

Tubal sterilization through electrocoagulation adversely affects ovarian reserve Posted: 21 Jun 2009 05:00 PM PDT Tubal sterilization by electrocoagulation is likely to have an adverse effect on ovarian reserve in the postoperative period, study results suggest.

Sperm plays a bigger role in embryo development than previously thought Posted: 21 Jun 2009 05:00 PM PDT Research shows that certain chromatin features in sperm may contribute to totipotency and imprinting patterns during development of the fetus.

Progesterone treatment fails to reduce early preterm birth in twin pregnancies Posted: 21 Jun 2009 05:00 PM PDT Progesterone treatment does not prevent early preterm birth in women with a twin pregnancy, despite showing promise in high-risk singleton pregnancies, study results suggest.

Pregnant women who snore have increased risk for gestational diabetes Posted: 21 Jun 2009 05:00 PM PDT Frequent snoring during pregnancy is associated with an increased risk for gestational diabetes, suggest US study results presented at the SLEEP 2009 23rd Annual Meeting in Seattle, Washington.

High incidence of climacteric symptoms, osteoporosis following surgical menopause Posted: 21 Jun 2009 05:00 PM PDT Surgical menopause is associated with higher rates of climacteric symptoms and osteoporosis, but not the metabolic syndrome, in women, particularly those with a menopausal duration of 5 years or less, suggest study results.

Twice-weekly conjugated estrogen cream effective for atrophic vaginitis Posted: 21 Jun 2009 05:00 PM PDT The commonly prescribed twice-weekly use of low-dose conjugate estrogens cream is as effective as the once-daily regimen in relieving symptoms of atrophic vaginitis in postmenopausal women, reveal study findings.

uVIN-related vulvar SCC increases risk for cervical (pre)malignancies Posted: 21 Jun 2009 05:00 PM PDT Women with a usual vulvar intraepithelial neoplasia-related vulvar squamous cell carcinoma have an increased incidence of cervical malignancies than women with differentiated VIN, show study results.

Ethnic inequalities exist in the uptake of cervical cancer screening Posted: 21 Jun 2009 05:00 PM PDT White British women are more likely to have a cervical smear than women of other ethnicity, while high socioeconomic status increases the likelihood for having a mammogram, show UK study results.

Letrozole plus progesterone increases clinical pregnancy rates in PCOS Posted: 21 Jun 2009 05:00 PM PDT Women with polycystic ovary syndrome who use letrozole for ovulation induction have higher clinical pregnancy rates when using intravaginal progesterone support than those who do not, suggest US study results.

Simple physician advice, follow-up sufficient for obese PCOS women to lose weight Posted: 21 Jun 2009 05:00 PM PDT Study results show that it is possible for obese women with polycystic ovary syndrome to achieve clinically significant and sustained weight loss with only simple advice given in a regular clinical care setting.

Proteomic analysis of HDL subpopulations reveals particle-specific protein clusters Posted: 21 Jun 2009 05:00 PM PDT High-density lipoprotein is composed of distinct particles containing unique apolipoprotein (apo) complements, researchers report.

<i>APOA5</i> variant influences benefit obtained from statin therapy Posted: 21 Jun 2009 05:00 PM PDT Apolipoprotein A5 gene variant influences individual response to statin therapy for dyslipidemia, report researchers.

Leadless pacing ‘feasible’ in heart failure Posted: 21 Jun 2009 05:00 PM PDT Researchers say they have demonstrated the feasibility of leadless pacing in heart failure patients, using ultrasound-mediated left ventricular stimulation.

CRP may not be independent risk factor for Type 2 diabetes Posted: 21 Jun 2009 05:00 PM PDT Evidence of association between serum C-reactive protein and risk for diabetes is confounded by central adiposity and other factors, study findings suggest.

Carotid IMT predicts cardiovascular risk in patients with Type 2 diabetes Posted: 21 Jun 2009 05:00 PM PDT Carotid intima-media thickness and urinary albumin excretion are independent predictors of cardiovascular events in patients with Type 2 diabetes, a Turkish study has found.

Leadless pacing ‘feasible’ in heart failure Posted: 21 Jun 2009 05:00 PM PDT Researchers say they have demonstrated the feasibility of leadless pacing in heart failure patients, using ultrasound-mediated left ventricular stimulation.

Coronary stenoses absent calcification linked to unstable symptoms Posted: 21 Jun 2009 05:00 PM PDT Patients with significant coronary stenoses but no coronary calcification are younger and more frequently have unstable symptoms than those with detectable coronary calcium, researchers have found.

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