Medical News

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• Obesity high in children presenting to ED for asthma
• International antibiotic guidelines for acute cough needed
• Understanding nasal cell rhinovirus resistance may lead to new asthma therapy
• Cigarette smoking normalizes deficits in sensorimotor gating in schizophrenia
• Differential muscarinic receptor expression in bipolar disorder and MDD
• Age does not influence recurrence risk in early breast cancer patients
• Midlife migraine with aura linked to brain lesions in elderly women
• Inactivity increases hospitalisation risk in asthma patients
• Breastfeeding may lower risk of symptoms in mothers with bowel disease
• SVG occlusion not linked to anti-heparin/PF4 antibodies
• CPAP may reduce death risk in patients with stroke and sleep apnea
• ED care suboptimal among many prostate cancer screened men
• Laser therapies ‘effective for BPH in small prostate’
• ER-positive/PR-negative breast cancer linked to carbohydrate intake
• Progestin-containing OC effectiveness not dependent on BMI
• Flu in pregnancy may boost schizophrenia risk in offspring
• Acupuncture shows promise for heartburn in pregnancy
• Assessing extreme drug resistance in EOC fails to alter patient outcomes
• Bazedoxifene, conjugated estrogens effective for postmenopausal vasomotor symptoms
• NO donors ineffective in preventing postmenopausal bone loss
• Addition of HPV test to cervical screening does not improve cervical cancer detection
• Hormonal contraceptives not linked to CIN, but DMPA increases risk for HPV infection
• Atorvastatin redistributes adiponectin to high molecular weight forms in Type 2 diabetes
• Glycated LDL important for determining CVD risk in Type 2 diabetics
• Waist-to-height ratio predicts adverse CV risk profile in young adults
• Atorvastatin redistributes adiponectin to high molecular weight forms in Type 2 diabetes
• Genetic risk score helps assess Type 2 diabetes risk
• Glycated LDL important for determining CVD risk in Type 2 diabetics
• Quality of life after pacemaker implantation unaffected by AF
• PCI centers with off-site surgery may not jeopardize survival

Obesity high in children presenting to ED for asthma Posted: 29 Jun 2009 05:00 PM PDT Asthmatic children presenting to the emergency department are more likely to be obese than children in the general population, research shows.

International antibiotic guidelines for acute cough needed Posted: 29 Jun 2009 05:00 PM PDT Researchers are calling for standardized antibiotic prescribing for acute cough after showing that variations in prescribing rates across Europe do not significantly alter recovery time.

Understanding nasal cell rhinovirus resistance may lead to new asthma therapy Posted: 29 Jun 2009 05:00 PM PDT Nasal epithelial cells are more resistant to rhinovirus infection than bronchial epithelial cells, say researchers who also report that susceptibility to infection is similar in nasal epithelial cells from those with and without asthma.

Cigarette smoking normalizes deficits in sensorimotor gating in schizophrenia Posted: 29 Jun 2009 05:00 PM PDT Study results show that cigarette smoking has a positive effect on sensorimotor gating in patients with schizophrenia, improving the prepulse inhibition deficit of the startle response to levels comparable to those seen in healthy individuals.

Differential muscarinic receptor expression in bipolar disorder and MDD Posted: 29 Jun 2009 05:00 PM PDT While muscarinic 2 receptor dysfunction is seen in both bipolar disorder and major depressive disorder, decreased CHRM3 expression occurs only in bipolar disorder, Australian scientists have found.

Age does not influence recurrence risk in early breast cancer patients Posted: 28 Jun 2009 05:00 PM PDT Young women with an early type of breast cancer called ductal carcinoma in situ do not have a greater risk of cancer recurrence after undergoing breast-conserving treatment than their older counterparts, study results show.

Midlife migraine with aura linked to brain lesions in elderly women Posted: 28 Jun 2009 05:00 PM PDT Women who suffer from migraines with aura are more likely to show evidence of brain lesions in old age than other women, researchers have found.

Inactivity increases hospitalisation risk in asthma patients Posted: 28 Jun 2009 05:00 PM PDT Asthma patients with low levels of physical activity are significantly more likely to be admitted to hospital for at least one overnight stay than their active counterparts, research shows.

Breastfeeding may lower risk of symptoms in mothers with bowel disease Posted: 28 Jun 2009 05:00 PM PDT In mothers with inflammatory bowel disease, breastfeeding is not associated with an increased risk of disease flares and may actually protect against an exacerbation of symptoms, researchers have found.

SVG occlusion not linked to anti-heparin/PF4 antibodies Posted: 28 Jun 2009 05:00 PM PDT Antibodies to heparin and platelet factor 4 complexes are not independently associated with early saphenous vein graft occlusion or adverse clinical outcomes after coronary artery bypass graft surgery, US researchers report.

CPAP may reduce death risk in patients with stroke and sleep apnea Posted: 28 Jun 2009 05:00 PM PDT Patients with ischemic stroke and moderate to severe obstructive sleep apnea may substantially reduce their risk for death by undergoing treatment with continuous positive airway pressure, results from prospective Spanish study show.

ED care suboptimal among many prostate cancer screened men Posted: 28 Jun 2009 05:00 PM PDT A significant proportion of individuals screened for prostate cancer who have erectile dysfunction do not have a primary care physician, despite the known links with cardiovascular disease, say US scientists.

Laser therapies ‘effective for BPH in small prostate’ Posted: 28 Jun 2009 05:00 PM PDT Benign prostatic hyperplasia (BPH)s in a small to moderate prostate can be effectively treated with holmium laser ablation or photoselective vaporization, say researchers.

ER-positive/PR-negative breast cancer linked to carbohydrate intake Posted: 28 Jun 2009 05:00 PM PDT Researchers have found evidence of a link between risk for estrogen receptor-positive and progesterone receptor-negative breast cancer and carbohydrate intake.

Progestin-containing OC effectiveness not dependent on BMI Posted: 28 Jun 2009 05:00 PM PDT The effectiveness of progestin-containing oral contraceptives do not decrease with increasing body mass index, show results from a large prospective active cohort surveillance study.

Flu in pregnancy may boost schizophrenia risk in offspring Posted: 28 Jun 2009 05:00 PM PDT Children born to mothers who were infected with the influenza B virus during pregnancy are at increased risk for developing schizophrenia, a case–control study has shown.

Acupuncture shows promise for heartburn in pregnancy Posted: 28 Jun 2009 05:00 PM PDT Acupuncture may alleviate dyspepsia during pregnancy, a randomized clinical trial has found.

Assessing extreme drug resistance in EOC fails to alter patient outcomes Posted: 28 Jun 2009 05:00 PM PDT Routinely assessing extreme drug resistance in women with epithelial ovarian cancer is not recommended as the results do not predict or alter treatment outcomes, US researchers believe.

Bazedoxifene, conjugated estrogens effective for postmenopausal vasomotor symptoms Posted: 28 Jun 2009 05:00 PM PDT The tissue-selective estrogen complex bazedoxifene/conjugated estrogens is tolerable and effective in treating moderate to severe postmenopausal hot flashes, show study results.

NO donors ineffective in preventing postmenopausal bone loss Posted: 28 Jun 2009 05:00 PM PDT The nitric oxide donor nitroglycerin is ineffective for preventing postmenopausal decreases in bone mineral density, according to US researchers.

Addition of HPV test to cervical screening does not improve cervical cancer detection Posted: 28 Jun 2009 05:00 PM PDT Adding human papilloma virus testing to routine liquid-based cytology screening does not increase detection of cervical cancer compared with cytology alone, show UK study results.

Hormonal contraceptives not linked to CIN, but DMPA increases risk for HPV infection Posted: 28 Jun 2009 05:00 PM PDT Study results suggest that hormonal contraceptive use is not associated with a increased risk for cervical intraepithelial neoplasia 1, 2-3, or greater.

Atorvastatin redistributes adiponectin to high molecular weight forms in Type 2 diabetes Posted: 28 Jun 2009 05:00 PM PDT Researchers have revealed a novel pleiotropic effect for atorvastatin in patients with Type 2 diabetes, demonstrating a redistribution of adiponectin from low molecular weight to more atherosclerosis protective, high molecular weight isoforms.

Glycated LDL important for determining CVD risk in Type 2 diabetics Posted: 28 Jun 2009 05:00 PM PDT Glycation of low-density lipoprotein cholesterol is likely to be atherogenic and the concentration of glycated LDL or apolipoprotein B is positively correlated with plasma levels of small dense-LDL particles, but not glycated hemoglobin, report researchers.

Waist-to-height ratio predicts adverse CV risk profile in young adults Posted: 28 Jun 2009 05:00 PM PDT A high waist-to-height ratio is significantly predictive of adverse cardiovascular risk in normal-weight younger adults, report researchers from the Bogalusa Heart Study.

Atorvastatin redistributes adiponectin to high molecular weight forms in Type 2 diabetes Posted: 28 Jun 2009 05:00 PM PDT Researchers have revealed a novel pleiotropic effect for atorvastatin in patients with Type 2 diabetes, demonstrating a redistribution of adiponectin from low molecular weight to more atherosclerosis protective, high molecular weight isoforms.

Genetic risk score helps assess Type 2 diabetes risk Posted: 28 Jun 2009 05:00 PM PDT A combined risk allele score calculated from variants in four genes associated with fasting plasma glucose levels significantly predicts risk for Type 2 diabetes, show results from the Dutch New Hoorn Study.

Glycated LDL important for determining CVD risk in Type 2 diabetics Posted: 28 Jun 2009 05:00 PM PDT Glycation of low-density lipoprotein cholesterol is likely to be atherogenic and the concentration of glycated LDL or apolipoprotein B is positively correlated with plasma levels of small dense-LDL particles, but not glycated hemoglobin, report researchers.

Quality of life after pacemaker implantation unaffected by AF Posted: 28 Jun 2009 05:00 PM PDT Quality of life among elderly patients with sick sinus syndrome who undergo pacemaker implantation is not affected by the presence of atrial fibrillation, US researchers have discovered.

PCI centers with off-site surgery may not jeopardize survival Posted: 28 Jun 2009 05:00 PM PDT Percutaneous coronary intervention centers without cardiac surgery facilities have similar risk-adjusted death rates to facilities with surgical back-up, a US registry suggests.

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