Medical News

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• Transforming growth factor cytokine implicated in COPD development
• Montelukast reduces eosinophil and mast cell numbers in asthma
• Data suggests hookworm infection a possible asthma therapy
• NSAID-induced antral ulcers linked with gene expression changes
• ‘Paradox’ of gastric cardiac acidity demonstrated
• Crohn’s disease behavior may influence early recurrence
• Cancer is major cause of death in schizophrenia patients
• High spring peak in suicide rates among mood disorder patients
• Jumping to conclusions in delusional patients ‘can be improved’
• Canadian CV deaths drop overall but proportion in women rises
• Hippocampal protein levels reduced in MDD and bipolar disorder
• Respiratory and heart rate coupling reduced in schizophrenia
• Impaired configural face processing found in schizophrenia
• Oseltamivir poses little risk in pregnant women treated for influenza H1N1
• ECT response quicker in bipolar versus unipolar depression
• Lithium serum levels and mood state affect ADRs in bipolar disorder

Transforming growth factor cytokine implicated in COPD development Posted: 28 Jun 2009 05:00 PM PDT Scientists who showed that levels of transforming growth factor ß1 are increased in patients with chronic obstructive pulmonary disease believe the cytokine is involved in the pathogenesis of the disease.

Montelukast reduces eosinophil and mast cell numbers in asthma Posted: 28 Jun 2009 05:00 PM PDT Treatment with a potent leukotriene receptor antagonist in mild asthmatic patients reduces the number of eosinophils and mast cells, research shows.

Data suggests hookworm infection a possible asthma therapy Posted: 28 Jun 2009 05:00 PM PDT Hookworm infection does not result in a clinically significant exacerbation of airway responsiveness in allergic individuals, a new feasibility study has shown.

NSAID-induced antral ulcers linked with gene expression changes Posted: 28 Jun 2009 05:00 PM PDT Patients who develop antral ulcers after treatment with nonsteroidal anti-inflammatory drugs may display distinct changes in mucosal gene expression, US research suggests.

‘Paradox’ of gastric cardiac acidity demonstrated Posted: 28 Jun 2009 05:00 PM PDT A custom-made catheter that allows pH recording at multiple sites has shown that the gastric cardia becomes more acidic after meals whereas the converse is true for the rest of the stomach.

Crohn’s disease behavior may influence early recurrence Posted: 28 Jun 2009 05:00 PM PDT The early recurrence of Crohn's disease after first resection may depend on whether its behaviour is penetrating or stricturing, research suggests.

Cancer is major cause of death in schizophrenia patients Posted: 25 Jun 2009 05:00 PM PDT Cancer is the second most common cause of death in schizophrenia patients after suicide, say researchers who call for greater efforts to improve cancer prevention and early detection in patients with the mental health disorder.

High spring peak in suicide rates among mood disorder patients Posted: 25 Jun 2009 05:00 PM PDT The seasonal spring peak in suicide rates is particularly high among patients with a history of mood disorders, research shows.

Jumping to conclusions in delusional patients ‘can be improved’ Posted: 24 Jun 2009 05:00 PM PDT The tendency to jump to conclusions during reasoning tasks among individuals with delusions can be improved, although better training is required for more severe cases, argue UK researchers.

Canadian CV deaths drop overall but proportion in women rises Posted: 24 Jun 2009 05:00 PM PDT Hospital admission and death rates for cardiovascular disease dropped by almost a third in Canada over the course of a decade, research shows, but by the start of this century more women than men were dying from the condition.

Hippocampal protein levels reduced in MDD and bipolar disorder Posted: 24 Jun 2009 05:00 PM PDT Reduced hippocampal brain-derived neurotrophic factor precursor expression is common to both major depressive disorder and bipolar disorder, UK investigators have discovered.

Respiratory and heart rate coupling reduced in schizophrenia Posted: 23 Jun 2009 05:00 PM PDT In schizophrenia patients, respiratory and heart rate coupling is reduced, with regularity of breathing linked to disease severity, potentially due to a lack of inhibitory brainstem control, say researchers.

Impaired configural face processing found in schizophrenia Posted: 23 Jun 2009 05:00 PM PDT Configural processing to integrate visual features into a perceptual whole is impaired in schizophrenia, with patients over-reliant on featural processing, the results of an Australian study indicate.

Oseltamivir poses little risk in pregnant women treated for influenza H1N1 Posted: 22 Jun 2009 05:00 PM PDT It is acceptable for pregnant women requiring treatment for the novel influenza A H1N1 virus to be treated treated with oseltamivir, research shows.

ECT response quicker in bipolar versus unipolar depression Posted: 22 Jun 2009 05:00 PM PDT There are no outcome differences from ultra-brief pulse electroconvulsive therapy between bipolar disorder and unipolar depression patients, but the former have a faster response, Belgian study findings suggest.

Lithium serum levels and mood state affect ADRs in bipolar disorder Posted: 22 Jun 2009 05:00 PM PDT Patient reporting and severity of adverse drug reactions during long-term lithium treatment for bipolar disorder are affected by both serum lithium concentration and mood state, say Dutch researchers

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