Medical News

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• High folate levels during pregnancy linked to increased asthma risk in children
• Combined ICS/LABA treatment cost-effective for COPD
• Obesity increases asthma risk in atopic, non-atopic adults
• Abnormal facial emotion processing linked to negative symptoms and deficit schizophrenia
• BD depression linked to abnormal amygdala functional connectivity to emotional stimuli
• Acidic perfusion provokes DIS without heartburn in healthy individuals
• Proteinuria linked to elevated VTE risk
• REGARDS highlights lack of AF awareness in Blacks
• Prognostic factor estimates unaffected by biochemical recurrence definition
• RARP ‘safe option’ for clinically localized prostate cancer
• Fewer adverse effects reported with hypofractionated radiotherapy regimen
• High Lp-PLA₂ levels increase risk for CHD in Type 2 diabetics
• Pulmonary embolism patients have low HDL cholesterol
• <i>CETP</i> variant associated with variable cholesterol response to statin therapy
• High Lp-PLA₂ levels increase risk for CHD in Type 2 diabetics
• Fasting blood glucose better than HbA1c for diagnosing diabetes
• Frail patients have worse prognosis after cardiac surgery
• US NHLBI outlines initiative to study Asian Americans’ CVD risk

High folate levels during pregnancy linked to increased asthma risk in children Posted: 02 Mar 2010 04:00 PM PST Children born to mothers with high plasma folate levels during pregnancy may be at increased risk for asthma, study results suggest.

Combined ICS/LABA treatment cost-effective for COPD Posted: 02 Mar 2010 04:00 PM PST Combined treatment with a fixed-dose inhaled corticosteroid and a long-acting beta-2 agonist is more cost-effective for the treatment of chronic obstructive pulmonary disease than either treatment alone or placebo, researchers have found.

Obesity increases asthma risk in atopic, non-atopic adults Posted: 02 Mar 2010 04:00 PM PST Obesity is associated with an increased risk for asthma in atopic and non-atopic men and women, research shows.

Abnormal facial emotion processing linked to negative symptoms and deficit schizophrenia Posted: 02 Mar 2010 04:00 PM PST Researchers have found that abnormalities in processing facial emotion are associated with the negative symptoms and deficit subtype of schizophrenia.

BD depression linked to abnormal amygdala functional connectivity to emotional stimuli Posted: 02 Mar 2010 04:00 PM PST US researchers suggest that abnormally elevated right amygdala-orbitofrontal cortical functional connectivity to sad stimuli reflects a predisposition to depression in individuals with bipolar disorder.

Acidic perfusion provokes DIS without heartburn in healthy individuals Posted: 02 Mar 2010 04:00 PM PST Researchers have found that, although weakly acidic solutions can provoke dilated intercellular spaces in healthy individuals after esophageal perfusion, most of these individuals do not experience heartburn or pain, suggesting that non-erosive reflux disease patients have other critical factors underlying their symptoms.

Proteinuria linked to elevated VTE risk Posted: 01 Mar 2010 04:00 PM PST In-hospital patients with proteinuria are more than three times as likely to develop venous thromboembolism as those without, US researchers have found.

REGARDS highlights lack of AF awareness in Blacks Posted: 01 Mar 2010 04:00 PM PST Black people are less likely than White people to be aware if they have atrial fibrillation and to receive treatment for the condition, show data from the REGARDS study.

Prognostic factor estimates unaffected by biochemical recurrence definition Posted: 01 Mar 2010 04:00 PM PST Prognostic factors for biochemical recurrence in men who have undergone radical prostatectomy should give similar results irrespective of the definition of biochemical recurrence used, research suggests.

RARP ‘safe option’ for clinically localized prostate cancer Posted: 01 Mar 2010 04:00 PM PST Robotic-assisted radical prostatectomy is a "safe option" for the treatment of clinically localized prostate cancer, say researchers who found low complication rates in a single-surgeon series of the procedures.

Fewer adverse effects reported with hypofractionated radiotherapy regimen Posted: 01 Mar 2010 04:00 PM PST Patients with breast cancer report fewer radiotherapy-associated adverse effects when treated with a hypofractionated regimen compared with the international standard regimen of 50 Gy in 25 fractions, UK research shows.

High Lp-PLA<sub>2</sub> levels increase risk for CHD in Type 2 diabetics Posted: 01 Mar 2010 04:00 PM PST People with Type 2 diabetes who have high levels of lipoprotein-associated phospholipase A2 have increased risk for incident coronary heart disease, report researchers.

Pulmonary embolism patients have low HDL cholesterol Posted: 01 Mar 2010 04:00 PM PST Patients with pulmonary embolism in the arterial trunk have significantly lower levels of high-density lipoprotein cholesterol than patients with pulmonary arterial non-trunk embolism, report researchers.

<i>CETP</i> variant associated with variable cholesterol response to statin therapy Posted: 01 Mar 2010 04:00 PM PST Variants in the cholesteryl ester transfer protein gene and in the apolipoprotein A-I gene are associated with poor cholesterol-lowering response to statins in an elderly population, report researchers.

High Lp-PLA<sub>2</sub> levels increase risk for CHD in Type 2 diabetics Posted: 01 Mar 2010 04:00 PM PST People with Type 2 diabetes who have high levels of lipoprotein-associated phospholipase A2 have increased risk for incident coronary heart disease, report researchers.

Fasting blood glucose better than HbA1c for diagnosing diabetes Posted: 01 Mar 2010 04:00 PM PST Results from a Chinese study suggest that fasting capillary blood glucose testing is more accurate for diagnosing Type 2 diabetes than glycated hemoglobin.

Frail patients have worse prognosis after cardiac surgery Posted: 01 Mar 2010 04:00 PM PST Frail patients undergoing cardiac surgery are less likely to survive and more likely to be discharged to institutional care than are nonfrail cardiac surgery patients, irrespective of age, a Canadian team reports in the journal Circulation.

US NHLBI outlines initiative to study Asian Americans’ CVD risk Posted: 01 Mar 2010 04:00 PM PST A working group from the US National Heart, Lung, and Blood Institute has developed an initiative to study cardiovascular disease in Asian Americans, a population that has grown dramatically over recent decades and for which data are scarce.

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