Medical News

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• COPD often not confirmed with spirometry
• Shared decision making benefits patients with poorly controlled asthma
• Study supports pollution link to asthma in childhood
• WBC linked to metabolic syndrome risk, severe psychiatric symptoms in schizophrenia
• Study replicates <i>BRD1</i> gene link to schizophrenia, BD susceptibility
• Acidic perfusion provokes DIS without heartburn in healthy individuals
• Fixed-dose enoxaparin thromboprophylaxis feasible for morbidly obese
• Alarm raised over INR threshold in stroke thrombolysis
• Sarcosine fails as marker for prostate cancer detection
• Fall in breast cancer incidence reflects decreased HRT use
• Adiponectin downregulation implicated in heart failure
• Metabolic syndrome components increase CV risk, but not syndrome itself
• Diabetics with a more interactive relationship style have reduced mortality
• Insulin glargine effective for treating nonobese and obese Type 2 diabetics
• Black, Hispanics with HF less likely to receive hospice treatment than Whites
• Benefit of PCI-center directed AMI care depends on referral region

COPD often not confirmed with spirometry Posted: 09 Mar 2010 04:00 PM PST Many patients with chronic obstructive pulmonary disease do not have their diagnosis confirmed with spirometry, results from a Swedish study suggest.

Shared decision making benefits patients with poorly controlled asthma Posted: 09 Mar 2010 04:00 PM PST Involving asthma patients in decisions about therapy can help improve treatment adherence and outcomes in those with poorly controlled disease, US research shows.

Study supports pollution link to asthma in childhood Posted: 09 Mar 2010 04:00 PM PST Exposure to increased levels of air pollution in early childhood is associated with an increased risk for asthma and related symptoms at the age of 8 years, research shows.

WBC linked to metabolic syndrome risk, severe psychiatric symptoms in schizophrenia Posted: 09 Mar 2010 04:00 PM PST White blood cell count may be useful for predicting the metabolic syndrome and more severe psychiatric symptoms in non-diabetic patients with schizophrenia, say US researchers.

Study replicates <i>BRD1</i> gene link to schizophrenia, BD susceptibility Posted: 09 Mar 2010 04:00 PM PST The bromo-domain containing protein 1 gene is implicated in the susceptibility to schizophrenia and bipolar disorder, confirm findings of an association study.

Acidic perfusion provokes DIS without heartburn in healthy individuals Posted: 09 Mar 2010 04:00 PM PST Researchers have found that, although weakly acidic solutions can provoke dilated intercellular spaces in healthy individuals after esophageal perfusion, most of these individuals do not experience heartburn or pain, suggesting that non-erosive reflux disease patients have other critical factors underlying their symptoms.

Fixed-dose enoxaparin thromboprophylaxis feasible for morbidly obese Posted: 08 Mar 2010 04:00 PM PST US researchers say that enoxaparin administered at a 0.5-mg/kg dose may be effective at preventing thrombosis in morbidly obese patients without increasing the risk for bleeding.

Alarm raised over INR threshold in stroke thrombolysis Posted: 08 Mar 2010 04:00 PM PST Stroke patients undergoing thrombolysis are at increased risk for symptomatic intracerebral hemorrhage if they are taking warfarin, even if their international normalized ratio is within recommended limits, research suggests.

Sarcosine fails as marker for prostate cancer detection Posted: 08 Mar 2010 04:00 PM PST Patients with and without prostate cancer cannot be differentiated by the levels of sarcosine in their urine following rectal digital examination, researchers report.

Fall in breast cancer incidence reflects decreased HRT use Posted: 08 Mar 2010 04:00 PM PST The incidence of invasive breast cancer in peri- and postmenopausal women fell in Scotland following a striking decrease in the use of hormone replacement therapy, research shows.

Adiponectin downregulation implicated in heart failure Posted: 08 Mar 2010 04:00 PM PST Levels of adiponectin are reduced in patients with both dilated cardiomyopathy and impaired coronary function, study findings show.

Metabolic syndrome components increase CV risk, but not syndrome itself Posted: 08 Mar 2010 04:00 PM PST Patients with the metabolic syndrome have greater progression of atherosclerosis than those without, but this is largely explained by high triglycerides and obesity, say researchers.

Diabetics with a more interactive relationship style have reduced mortality Posted: 08 Mar 2010 04:00 PM PST Patients with diabetes who have a "more interactive" relationship style and who are more inclined to seek social support when needed have lower 5-year mortality than those who do not, show study results.

Insulin glargine effective for treating nonobese and obese Type 2 diabetics Posted: 08 Mar 2010 04:00 PM PST Results from a subgroup analysis of the ATLANTUS trial show that treatment with insulin glargine is effective for lowering glycated hemoglobin, without substantial weight gain, in obese and nonobese individuals with Type 2 diabetes.

Black, Hispanics with HF less likely to receive hospice treatment than Whites Posted: 08 Mar 2010 04:00 PM PST Black and Hispanic patients with heart failure are less likely to use hospice care than are White patients, a study of a US national sample of Medicare beneficiaries indicates.

Benefit of PCI-center directed AMI care depends on referral region Posted: 08 Mar 2010 04:00 PM PST The benefit of regionalizing care of acute myocardial infarction patients to hospitals capable of performing percutaneous coronary intervention depends on the hospital referral region.

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